LOCUS HUMDD4 1155 bp mRNA linear HUM 11-FEB-2003
DEFINITION Homo sapiens mRNA for 3 alpha-hydroxysteroid/dihydrodiol
dehydrogenase DD4, partial cds.
ACCESSION D26125
VERSION D26125.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1155)
AUTHORS Hara,A.
TITLE Direct Submission
JOURNAL Submitted (09-DEC-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Akira Hara
Gifu Pharmaceutical University, Laboratory of Biochemistry;
Mitahora-higashi, Gifu, Gifu 502, Japan
REFERENCE 2
AUTHORS Winters,C.J., Molowa,D.T. and Guzelian,P.S.
TITLE Isolation and characterization of cloned cDNAs encoding human
liver chlordecone reductase
JOURNAL J. Biochem. 29, 1080-1087 (1990)
REFERENCE 3
AUTHORS Deyashiki,Y., Ogasawara,A., Nakayama,T., Nakanishi,M., Miyabe,Y.,
Sato,K. and Hara,A.
TITLE Molecular cloning of two human liver 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are
identical with chlordecone reductase and bile-acid binder
JOURNAL Biochem. J. 299, 545-552 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..1155
/clone="11"
/clone_lib="lambda gt11"
/db_xref="H-InvDB:HIT000101140"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="Caucasian"
/organism="Homo sapiens"
/tissue_type="liver"
CDS <1..968
/codon_start=3
/EC_number="1.3.1.20"
/note="dihydrodiol dehydrogenase isozyme DD4"
/product="3 alpha-hydroxysteroid/dihydrodiol
dehydrogenase DD4"
/protein_id="BAA05122.1"
/translation="PKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGF
RHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLK
KLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKS
IGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG
TQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIR
ENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY"
regulatory 1135..1140
/regulatory_class="polyA_signal_sequence"
polyA_site 1155
BASE COUNT 330 a 265 c 269 g 291 t
ORIGIN
1 atcccaaata tcagcgtgta gagctaaatg atggtcactt catgcccgta ttgggatttg
61 gcacctatgc acctccagag gttccgagga acagagctgt agaggtcacc aaattagcaa
121 tagaagctgg cttccgccat attgattctg cttatttata caataatgag gagcaggttg
181 gactggccat ccgaagcaag attgcagatg gcagtgtgaa gagagaagac atattctaca
241 cttcaaagct ttggtgcact ttctttcaac cacagatggt ccaaccagcc ttggaaagct
301 cactgaaaaa acttcaactg gactatgttg acctctatct tcttcatttc ccaatggctc
361 tcaagccagg tgagacgcca ctaccaaaag atgaaaatgg aaaagtaata ttcgacacag
421 tggatctctc tgccacatgg gaggtcatgg agaagtgtaa ggatgcagga ttggccaagt
481 ccatcggggt gtcaaacttc aactgcaggc agctggagat gatcctcaac aagccaggac
541 tcaagtacaa gcctgtctgc aaccaggtag aatgtcatcc ttacctcaac cagagcaaac
601 tgctggattt ctgcaagtca aaagacattg ttctggttgc ccacagtgct ctgggaaccc
661 aacgacataa actatgggtg gacccaaact ccccagttct tttggaggac ccagttcttt
721 gtgccttagc aaagaaacac aaacgaaccc cagccctgat tgccctgcgc taccagctgc
781 agcgtggggt tgtggtcctg gccaagagct acaatgagca gcggatcaga gagaacatcc
841 aggtttttga attccagttg acatcagagg atatgaaagt tctagatggt ctaaacagaa
901 attatcgata tgttgtcatg gattttctta tggaccatcc tgattatcca ttttcagatg
961 aatattagca tagagggtgt tgcacgacat ctagcagaag gccctgtgtg tggatggtga
1021 tgcagaggat gtctctatgc tggtgactgg acacacggcc tctggttaaa tccctcccct
1081 cctgcttggc aacttcagct agctagatat atccatggtc cagaaagcaa acataataaa
1141 tttttatctt gaagt
//