LOCUS HUMPTPFK 2591 bp mRNA linear HUM 13-SEP-2008
DEFINITION Homo sapiens mRNA for platelet-type phosphofructokinase, complete
cds.
ACCESSION D25328
VERSION D25328.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2591)
AUTHORS Eto,K.
TITLE Direct Submission
JOURNAL Submitted (22-NOV-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Kazuhiro Eto
Faculty of Medicine, University of Tokyo, The Third Dept. of
Internal Medicine; 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan
REFERENCE 2
AUTHORS Simpson,C.J. and Fothergill-Gilmore,L.A.
TITLE Isolation and sequence of a cDNA encoding human platelet
phosphofructokinase
JOURNAL Biochem. Biophys. Res. Commun. 180, 197-203 (1991)
REFERENCE 3
AUTHORS Eto,K., Sakura,H., Yasuda,K., Hayakawa,T., Kawasaki,E.,
Moriuchi,R., Nagataki,S., Yazaki,Y. and Kadowaki,T.
TITLE Cloning of a complete protein-coding sequence of human
platelet-type phosphofructokinase isozyme from pancreatic islet
JOURNAL Cell. Mol. Biol. Res. 198, 990-998 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..2591
/chromosome="10"
/clone="F7"
/clone_lib="lambda gt11"
/db_xref="H-InvDB:HIT000101126"
/db_xref="taxon:9606"
/map="10p15.3-p15.2"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="pancreatic islets"
CDS 34..2388
/codon_start=1
/EC_number="2.7.1.11"
/product="platelet-type phosphofructokinase"
/protein_id="BAA04998.1"
/translation="MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQGMNAAVR
AVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFR
TREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQ
KYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMG
RHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAI
DTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALL
EATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN
TYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGF
DGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGG
FEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRI
KQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTE
KMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFD
RNFGTKISARAMEWITAKLKEARGRGKKFTTDDSICVLGISKRNVIFQPVAELKKQTD
FEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWSV"
variation 1314
/replace="a"
variation 1392
/replace="t"
misc_difference 1524..1526
/citation=[2]
/replace=""
variation 1827
/replace="t"
misc_difference 2129
/citation=[2]
/replace="a"
variation 2432
/replace="c"
variation 2525
/replace="c"
regulatory 2586..2591
/regulatory_class="polyA_signal_sequence"
BASE COUNT 592 a 713 c 790 g 496 t
ORIGIN
1 cccggacgtg cggctcccct cggcctcctc gccatggacg cggacgactc ccgggccccc
61 aagggctcct tgcggaagtt cctggagcac ctctccgggg ccggcaaggc catcggcgtg
121 ctgaccagcg gcggggatgc tcaaggtatg aacgctgccg tccgtgccgt ggtgcgcatg
181 ggtatctacg tgggggccaa ggtgtacttc atctacgagg gctaccaggg catggtggac
241 ggaggctcaa acatcgcaga ggccgactgg gagagtgtct ccagcatcct gcaagtgggc
301 gggacgatca ttggcagtgc gcggtgccag gccttccgca cgcgggaagg ccgcctgaag
361 gctgcttgca acctgctgca gcgcggcatc accaacctgt gtgtgatcgg cggggacggg
421 agcctcaccg gggccaacct cttccggaag gagtggagtg ggctgctgga ggagctggcc
481 aggaacggcc agatcgataa ggaggccgtg cagaagtacg cctacctcaa cgtggtgggc
541 atggtgggct ccatcgacaa tgatttctgc ggcaccgaca tgaccatcgg cacggactcc
601 gccctgcaca ggatcatcga ggtcgtcgac gccatcatga ccacggccca gagccaccag
661 aggaccttcg ttctggaggt gatgggacga cactgtgggt acctggccct ggtgagtgcc
721 ttggcctgcg gtgcggactg ggtgttcctt ccagaatctc caccagagga aggctgggag
781 gagcagatgt gtgtcaaact ctcggagaac cgtgcccgga aaaaaaggct gaatattatt
841 attgtggctg aaggagcaat tgatacccaa aataaaccca tcacctctga gaaaatcaaa
901 gagcttgtcg tcacgcagct gggctatgac acacgtgtga ccatcctcgg gcacgtgcag
961 agaggaggga ccccttcggc attcgacagg atcttggcca gccgcatggg agtggaggca
1021 gtcatcgcct tgctagaggc caccccggac accccagctt gcgtcgtgtc actgaacggg
1081 aaccacgccg tgcgcctgcc gctgatggag tgcgtgcaga tgactcagga tgtgcagaag
1141 gcgatggacg agaggagatt tcaagatgcg gttcgactcc gagggaggag ctttgcgggc
1201 aacctgaaca cctacaagcg acttgccatc aagctgccgg atgatcagat cccaaagacc
1261 aattgcaacg tagctgtcat caacgtgggg gcacccgcgg ctgggatgaa cgcggccgta
1321 cgctcagctg tgcgcgtggg cattgccgac ggccacagga tgctcgccat ctatgatggc
1381 tttgacggct tcgccaaggg ccagatcaaa gaaatcggct ggacagatgt cgggggctgg
1441 accggccaag gaggctccat tcttgggaca aaacgcgttc tcccggggaa gtacttggaa
1501 gagatcgcca cacagatgcg cacgcacagc atcaacgcgc tgctgatcat cggtggattc
1561 gaggcctacc tgggactcct ggagctgtca gccgcccggg agaagcacga ggagttctgt
1621 gtccccatgg tcatggttcc cgctactgtg tccaacaatg tgccgggttc cgatttcagc
1681 atcggggcag acaccgccct gaacactatc accgacacct gcgaccgcat caagcagtcc
1741 gccagcggaa ccaagcggcg cgtgttcatc atcgagacca tgggcggcta ctgtggctac
1801 ctggccaaca tgggggggct cgcggccgga gctgatgccg catacatttt cgaagagccc
1861 ttcgacatca gggatctgca gtccaacgtg gagcacctga cggagaaaat gaagaccacc
1921 atccagagag gccttgtgct cagaaatgag agctgcagtg aaaactacac caccgacttc
1981 atttaccagc tgtattcaga agagggcaaa ggcgtgtttg actgcaggaa gaacgtgctg
2041 ggtcacatgc agcagggtgg ggcaccctct ccatttgata gaaactttgg aaccaaaatc
2101 tctgccagag ctatggagtg gatcactgca aaactcaagg aggcccgggg cagaggaaaa
2161 aaatttacca ccgatgattc catttgtgtg ctgggaataa gcaaaagaaa cgttattttt
2221 caacctgtgg cagagctgaa gaagcaaacg gattttgagc acaggattcc caaagaacag
2281 tggtggctca agctacggcc cctcatgaaa atcctggcca agtacaaggc cagctatgac
2341 gtgtcggact caggccagct ggaacatgtg cagccctgga gtgtctgacc cagtcccgcc
2401 tgcatgtgcc tgcagccacc gtggactgtc tgtttttgta acacttaagt tattttatca
2461 gcactttatg cacgtattat tgacattaat acctaatcgg cgagtgccca tctgccccac
2521 cagctccagt gcgtgctgtc tgtggagtgt gtctcatgct ttcagatgtg catatgagca
2581 gaattaatta a
//