LOCUS HUMIAS 3588 bp mRNA linear HUM 26-SEP-2008
DEFINITION Homo sapiens mRNA for integrin alpha subunit, complete cds.
ACCESSION D25303
VERSION D25303.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3588)
AUTHORS Takahashi,T.
TITLE Direct Submission
JOURNAL Submitted (18-NOV-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Takashi Takahashi
Aichi Cancer Center Research Institute, Lab of Ultrastructure
Research; 1-1 Kanokoden, Chikusaku, Nagoya, Aichi 464, Japan
REFERENCE 2
AUTHORS Hibi,K., Yamakawa,K., Ueda,R., Horio,Y., Murata,Y., Tamari,M.,
Uchida,K., Takahashi,T., Nakamura,Y. and Takahashi,T.
TITLE Aberrant upregulation of a novel integrin alpha subunit gene at
3p21.3 in small cell lung cancer
JOURNAL Oncogene 9, 611-619 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..3588
/chromosome="3"
/clone="FL1, L5F1, F1F4"
/db_xref="H-InvDB:HIT000101125"
/db_xref="taxon:9606"
/dev_stage="fetus and adult"
/map="3p21.3"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="lung"
CDS 52..3159
/codon_start=1
/note="integrin alpha-RLC"
/product="integrin alpha subunit"
/protein_id="BAA04984.1"
/translation="MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPA
DSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDM
ARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHG
FCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWA
GTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGK
VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE
GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDF
AGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFM
SDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPEE
IGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRV
QDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED
CAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELF
FINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFI
VTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDD
LECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCS
FQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESR
TIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNL
EPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDW
VQKNQ"
BASE COUNT 871 a 915 c 964 g 838 t
ORIGIN
1 ccgcgctcgg cgccctgctc gccgggcaga ggggaaggcg gccggctggg gatgggcggc
61 ccggctgcgc cgaggggcgc cgggaggctc cgcgcgctgc tgctggcgct ggtggtcgcg
121 gggatccccg cgggcgccta caacctcgac ccgcagcgcc ccgtgcactt ccagggcccc
181 gctgactcgt tcttcggcta cgcagttctg gagcatttcc acgacaacac gcgctgggtc
241 cttgtgggcg caccaaaggc agattccaaa tacagccctt cagtgaagtc tcctggggct
301 gtgtttaagt gccgtgttca caccaaccct gaccggagat gcaccgaact ggacatggct
361 cgagggaaga atcggggcac gtcctgcgga aagacctgcc gggaagaccg cgatgatgag
421 tggatggggg tgagcctggc ccgacagccc aaggctgatg gccgtgtgtt ggcctgtgct
481 catcgctgga agaacatcta ctatgaagcc gaccacatcc taccccatgg cttctgctac
541 atcatcccct ccaacctcca ggccaaaggc aggacactga tcccttgcta tgaagagtat
601 aagaagaagt acggagagga acacggctcc tgccaggctg ggatagcggg cttcttcact
661 gaggagctgg tggtgatggg tgctccaggg tcattttatt gggctggaac catcaaagtg
721 ctgaacctta cggacaacac ctatttaaaa ctgaacgacg aagtgatcat gaacaggcgg
781 tacacctacc tgggctacgc agtgaccgct ggccacttct ctcacccgtc caccattgat
841 gtggtaggag gtgccccaca ggacaaaggc atcggcaagg tttatatttt cagagctgac
901 cgaagatcag gcaccttaat taagatcttt caagcatcag gtaaaaagat gggctcttac
961 ttcggctcct ccttgtgcgc agttgacctg aatggggacg gcctctctga cctgctggtg
1021 ggggccccca tgttttctga gatcagggat gagggacagg tcactgtcta catcaacaga
1081 ggaaatggag ccctcgagga gcagctggct ctgactgggg atggtgccta caatgcgcac
1141 tttggagaga gcattgccag cctggacgat ctggacaatg atgggttccc agatgtggcc
1201 attggtgcac ccaaggagga tgacttcgca ggggcggtct atatctatca tggtgatgcc
1261 ggtgggatag tccctcagta ctcaatgaaa ctgtctgggc agaagataaa tccagtgctc
1321 cggatgtttg gtcagtccat atcgggaggc attgatatgg atggaaatgg ctatcctgat
1381 gtcactgttg gagccttcat gtccgacagc gtggttcttc tcagagcaag gcctgtcatt
1441 acggtggatg tctccatctt cctcccgggc tccatcaaca tcacagcgcc tcagtgtcac
1501 gacggacagc agcctgtgaa ctgcctgaac gtcaccacct gcttcagctt ccatggcaaa
1561 cacgttccag aagagattgg cctgaattat gttctgatgg ctgacgtggc caaaaaggag
1621 aagggccaga tgcccagggt ctactttgtg ctgctgggag agaccatggg tcaggtcaca
1681 gagaagctgc agctgactta catggaggag acgtgtcgtc actatgtggc ccatgtgaag
1741 cggagggtgc aggacgtcat cagcccgatc gtgtttgaag cagcctacag cctcagtgag
1801 catgtgactg gagaggagga gagggaactg ccgcctctga caccagttct ccgctggaaa
1861 aagggacaaa agattgccca aaagaatcag actgtttttg aaaggaattg ccgttcagag
1921 gactgtgccg cagacctgca gcttcagggt aaactgctgc tctccagtat ggatgagaaa
1981 accctgtatc tagctttggg ggctgtgaag aacatctccc taaacatctc tatctccaac
2041 ctcggagatg atgcctatga tgccaacgtg tccttcaatg tttcccggga gctcttcttc
2101 atcaacatgt ggcagaagga ggagatgggc atctcctgtg agctgctgga atcggacttc
2161 ctcaaatgca gcgtgggatt tcctttcatg aggtcaaagt caaagtatga attcagcgtg
2221 atctttgata caagccacct gtctggggaa gaggaagttc tcagcttcat tgttactgct
2281 cagagtggca acacggagcg ctctgaatcc ctgcatgaca acaccctcgt gctgatggtg
2341 ccactgatgc acgaggtgga cacgtccatc accggaatca tgtctccaac ctcctttgta
2401 tatggcgagt ccgtggacgc agccaacttc attcagctgg atgacctgga gtgtcacttt
2461 cagcccatca atatcaccct tcaggtctac aacactggcc caagcaccct tccagggtca
2521 tctgtcagca tctctttccc taatcgactc tcatctggtg gtgcagagat gtttcatgtc
2581 caggaaatgg tggtgggcca agagaaggga aactgctctt tccagaaaaa cccaactccc
2641 tgcatcatcc ctcaagaaca agaaaatatc ttccacacaa tatttgcttt tttcacaaag
2701 tctggaagaa aagtcttgga ctgtgaaaaa ccaggaattt cttgcctaac agcacactgt
2761 aactttagtg ctcttgctaa agaagaaagt cgtactatag acatttacat gctgctgaac
2821 acagaaatac tgaaaaagga cagttcgtct gtcatccagt tcatgtcccg cgccaaggtg
2881 aaggtggatc ctgccctaag ggtggtggaa atagctcatg ggaacccaga agaggtgacg
2941 gtggtcttcg aggccctgca caatctggag ccccgtggct acgtcgtggg gtggatcatc
3001 gccatcagtt tgttggtggg aatcctcatc ttcctgctgc tggccgtgct gctctggaag
3061 atgggcttct ttcgccgaag gtacaaagaa attatcgaag ctgagaagaa ccggaaagag
3121 aatgaagaca gttgggactg ggtccagaaa aaccagtgag ctgccacacc agtcacatga
3181 cctgatcact agcctgtcat ccttggtctt tgtatcttcc atatttggaa aaaaaaaatc
3241 ttctccagat ttttcggagg ccccactgat gctgttctct tcttcattct atcaagccca
3301 ggtgccagcc tgaggcagcc acttcggcca ggtcacacga ccgggggcag caccacttcg
3361 ctttaaagac tctgaacttt ggagagtgac agagccgagc aatatttagg atgcaacacg
3421 catggtcacc ctcaggggaa aactgttaaa gtatttttat aaatataagc cttttatact
3481 gattattctt ttatatttgt atcgatatta tttctattaa atagttataa ttcactcaag
3541 cactgattct ggcctaaaat cttggaagtc catgaataca aattttaa
//