LOCUS HUMPTPB2 8062 bp mRNA linear HUM 11-FEB-2003
DEFINITION Homo sapiens PTP-BAS mRNA for protein tyrosine phosphatase type 2,
complete cds.
ACCESSION D21210
VERSION D21210.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8062)
AUTHORS Maekawa,K.
TITLE Direct Submission
JOURNAL Submitted (15-OCT-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Kazuhiko Maekawa
Shionogi Institute for Medical Science; 2-5-1 Mishima, Settsu,
Osaka 566, Japan
REFERENCE 2
AUTHORS Maekawa,K., Imagawa,N., Nagamatsu,M. and Harada,S.
TITLE Molecular cloning of a novel protein-tyrosine phosphatase
containing a membrane-binding domain and GLGF repeats
JOURNAL FEBS Lett. 337, 200-206 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..8062
/cell_line="KU812E"
/cell_type="basophilic leukemia cell"
/clone_lib="Lambda Zap II"
/db_xref="H-InvDB:HIT000101091"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="clones BAS-[1-4]"
/organism="Homo sapiens"
CDS 64..7464
/codon_start=1
/gene="PTP-BAS"
/product="protein tyrosine phosphatase type 2"
/protein_id="BAA04751.1"
/translation="MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADP
AALGFIISPWSLLLLPSGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIY
SLGMTLYWGADYEVPQSQPIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNS
NCAPSFSYVKHLVKLVLGNLSGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSD
VLDIQKPPLSHQTFLNKGLSKSMGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQ
FKTSGPEKKPIPGIDVLSKKKIWASSMDLLCTADRDFSSGETATYRRCHPEAVTVRTS
TTPRKKEARYSDGSIALDIFGPQKMDPIYHTRELPTSSAISSALDRIRERQKKLQVLR
EAMNVEEPVRRYKTYHGDVFSTSSESPSIISSESDFRQVRRSEASKRFESSSGLPGVD
ETLSQGQSQRPSRQYETPFEGNLINQEIMLKRQEEELMQLQAKMALRQSRLSLYPGDT
IKASMLDITRDPLREIALETAMTQRKLRNFFGPEFVKMTIEPFISLDLPRSILTKKGK
NEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDNEYF
FVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQ
LRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDL
SYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVC
SKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSDGIKHGFQTDNSKICQY
LLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTGSLAS
STLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHD
LSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASL
NRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQ
IIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ
NAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRG
TLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGS
PSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQ
ESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYV
KAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSP
TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGF
SFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVI
SALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTS
SDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMV
SQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESA
SSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTV
TKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTV
RLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVA
AIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSA
VSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGK
LSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITW
GNDELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLD
QGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASF
IKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN
ILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPS
QPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVR
CMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK"
regulatory 7536..7541
/regulatory_class="polyA_signal_sequence"
regulatory 7610..7615
/regulatory_class="polyA_signal_sequence"
regulatory 7815..7820
/regulatory_class="polyA_signal_sequence"
regulatory 8039..8044
/regulatory_class="polyA_signal_sequence"
polyA_site 8062
BASE COUNT 2576 a 1662 c 1733 g 2091 t
ORIGIN
1 cgtccctgca gccctcgccc ggcgctccag tagcaggacc cggtctcggg accagccggt
61 aatatgcacg tgtcactagc tgaggccctg gaggttcggg gtggaccact tcaggaggaa
121 gaaatatggg ctgtattaaa tcaaagtgct gaaagtctcc aagaattatt cagaaaagta
181 agcctagctg atcctgctgc ccttggcttc atcatttctc catggtctct gctgttgctg
241 ccatctggta gtgtgtcatt tacagatgaa aatatttcca atcaggatct tcgagcattc
301 actgcaccag aggttcttca aaatcagtca ctaacttctc tctcagatgt tgaaaagatc
361 cacatttatt ctcttggaat gacactgtat tggggggctg attatgaagt gcctcagagc
421 caacctatta agcttggaga tcatctcaac agcatactgc ttggaatgtg tgaggatgtt
481 atttacgctc gagtttctgt tcggactgtg ctggatgctt gcagtgccca cattaggaat
541 agcaattgtg caccctcatt ttcctacgtg aaacacttgg taaaactggt tctgggaaat
601 ctttctggga cagatcagct ttcctgtaac agtgaacaaa agcctgatcg aagccaggct
661 attcgagatc gattgcgagg aaaaggatta ccaacaggaa gaagctctac ttctgatgta
721 ctagacatac aaaagcctcc actctctcat cagacctttc ttaacaaagg gcttagtaaa
781 tctatgggat ttctgtccat caaagataca caagatgaga attatttcaa ggacatttta
841 tcagataatt ctggacgtga agattctgaa aatacattct ccccttacca gttcaaaact
901 agtggcccag aaaaaaaacc catccctggc attgatgtgc tttctaagaa gaagatctgg
961 gcttcatcca tggacttgct ttgtacagct gacagagact tctcttcagg agagactgcc
1021 acatatcgtc gttgtcaccc tgaggcagta acagtgcgga cttcaactac tcctagaaaa
1081 aaggaggcaa gatactcaga tggaagtata gccttggata tctttggccc tcagaaaatg
1141 gatccaatat atcacactcg agaattgccc acctcctcag caatatcaag tgctttggac
1201 cgaatccgag agagacaaaa gaaacttcag gttctgaggg aagccatgaa tgtagaagaa
1261 ccagttcgaa gatacaaaac ttatcatggt gatgtcttta gtacctccag tgaaagtcca
1321 tctattattt cctctgaatc agatttcaga caagtgagaa gaagtgaagc ctcaaagagg
1381 tttgaatcca gcagtggtct cccaggggta gatgaaacct taagtcaagg ccagtcacag
1441 agaccgagca gacaatatga aacacccttt gaaggcaact taattaatca agagatcatg
1501 ctaaaacggc aagaggaaga actgatgcag ctacaagcca aaatggccct tagacagtct
1561 cggttgagcc tatatccagg agacacaatc aaagcgtcca tgcttgacat caccagggat
1621 ccgttaagag aaattgccct agaaacagcc atgactcaaa gaaaactgag gaatttcttt
1681 ggccctgagt ttgtgaaaat gacaattgaa ccatttatat ctttggattt gccacggtct
1741 attcttacta agaaagggaa gaatgaggat aaccgaagga aagtaaacat aatgcttctg
1801 aacgggcaaa gactggaact gacctgtgat accaaaacta tatgtaaaga tgtgtttgat
1861 atggttgtgg cacatattgg cttagtagag catcatttgt ttgctttagc taccctcaaa
1921 gataatgaat atttctttgt tgatcctgac ttaaaattaa ccaaagtggc cccagaggga
1981 tggaaagaag aaccaaagaa aaagaccaaa gccactgtta attttacttt gtttttcaga
2041 attaaatttt ttatggatga tgttagtcta atacaacata ctctgacgtg tcatcagtat
2101 taccttcagc ttcgaaaaga tattttggag gaaaggatgc actgtgatga tgagacttcc
2161 ttattgctgg catccttggc tctccaggct gagtatggag attatcaacc agaggttcat
2221 ggtgtgtctt actttagaat ggagcactat ttgcccgcca gagtgatgga gaaacttgat
2281 ttatcctata tcaaagaaga gttacccaaa ttgcataata cctatgtggg agcttctgaa
2341 aaagagacag agttagaatt tttaaaggtc tgccaaagac tgacagaata tggagttcat
2401 tttcaccgag tgcaccctga gaagaagtca caaacaggaa tattgcttgg agtctgttct
2461 aaaggtgtcc ttgtgtttga agttcacaat ggagtgcgca cattggtcct tcgctttcca
2521 tggagggaaa ccaagaaaat atctttttct aaaaagaaaa tcacattgca aaatacatca
2581 gatggaataa aacatggctt ccagacagac aacagtaaga tatgccagta cctgctgcac
2641 ctctgctctt accagcataa gttccagcta cagatgagag caagacagag caaccaagat
2701 gcccaagata ttgagagagc ttcgtttagg agcctgaatc tccaagcaga gtctgttaga
2761 ggatttaata tgggacgagc aatcagcact ggcagtctgg ccagcagcac cctcaacaaa
2821 cttgctgttc gacctttatc agttcaagct gagattctga agaggctatc ctgctcagag
2881 ctgtcgcttt accagccatt gcaaaacagt tcaaaagaga agaatgacaa agcttcatgg
2941 gaggaaaagc ctagagagat gagtaaatca taccatgatc tcagtcaggc ctctctctat
3001 ccacatcgga aaaatgtcat tgttaacatg gaacccccac cacaaaccgt tgcagagttg
3061 gtgggaaaac cttctcacca gatgtcaaga tctgatgcag aatctttggc aggagtgaca
3121 aaacttaata attcaaagtc tgttgcgagt ttaaatagaa gtcctgaaag gaggaaacat
3181 gaatcagact cctcatccat tgaagaccct gggcaagcat atgttctaga tgtgctacac
3241 aaaagatgga gcatagtatc ttcaccagaa agggagatca ccttagtgaa cctgaaaaaa
3301 gatgcaaagt atggcttggg atttcaaatt attggtgggg agaagatggg aagactggac
3361 ctaggcatat ttatcagttc agttgcccct ggaggaccag ctgacttgga tggatgcttg
3421 aagccaggag accgtttgat atctgtgaat agtgtgagtc tggagggagt cagccaccat
3481 gctgcaattg aaattttgca aaatgcacct gaagatgtga cacttgttat ctctcagcca
3541 aaagaaaaga tatccaaagt gccttctact cctgtgcatc tcaccaatga gatgaaaaac
3601 tacatgaaga aatcttccta catgcaagac agtgctatag attcttcttc caaggatcac
3661 cactggtcac gtggtaccct gaggcacatc tcggagaact cctttgggcc atctgggggc
3721 ctgcgggaag gaagcctgag ttctcaagat tccaggactg agagtgccag cttgtctcaa
3781 agccaggtca atggtttctt tgccagccat ttaggtgacc aaacctggca ggaatcacag
3841 catggcagcc cttccccatc tgtaatatcc aaagccaccg agaaagagac tttcactgat
3901 agtaaccaaa gcaaaactaa aaagccaggc atttctgatg taactgatta ctcagaccgt
3961 ggagattcag acatggatga agccacttac tccagcagtc aggatcatca aacaccaaaa
4021 caggaatctt cctcttcagt gaatacatcc aacaagatga attttaaaac tttttcttca
4081 tcacctccta agcctggaga tatctttgag gttgaactgg ctaaaaatga taacagcttg
4141 gggataagtg tcacgggagg tgtgaatacg agtgtcagac atggtggcat ttatgtgaaa
4201 gctgttattc cccagggagc agcagagtct gatggtagaa ttcacaaagg tgatcgcgtc
4261 ctagctgtca atggagttag tctagaagga gccacccata agcaagctgt ggaaacactg
4321 agaaatacag gacaggtggt tcatctgtta ttagaaaagg gacaatctcc aacatctaaa
4381 gaacatgtcc cggtaacccc acagtgtacc ctttcagatc agaatgccca aggtcaaggc
4441 ccagaaaaag tgaagaaaac aactcaggtc aaagactaca gctttgtcac tgaagaaaat
4501 acatttgagg taaaattatt taaaaatagc tcaggtctag gattcagttt ttctcgagaa
4561 gataatctta taccggagca aattaatgcc agcatagtaa gggttaaaaa gctctttcct
4621 ggacagccag cagcagaaag tggaaaaatt gatgtaggag atgttatctt gaaagtgaat
4681 ggagcctctt tgaaaggact atctcagcag gaagtcatat ctgctctcag gggaactgct
4741 ccagaagtat tcttgcttct ctgcagacct ccacctggtg tgctaccgga aattgatact
4801 gcgcttttga ccccacttca gtctccagca caagtacttc caaacagcag taaagactct
4861 tctcagccat catgtgtgga gcaaagcacc agctcagatg aaaatgaaat gtcagacaaa
4921 agcaaaaaac agtgcaagtc cccatccaga agagacagtt acagtgacag cagtgggagt
4981 ggagaagatg acttagtgac agctccagca aacatatcaa attcgacctg gagttcagct
5041 ttgcatcaga ctctaagcaa catggtatca caggcacaga gtcatcatga agcacccaag
5101 agtcaagaag ataccatttg taccatgttt tactatcctc agaaaattcc caataaacca
5161 gagtttgagg acagtaatcc ttcccctcta ccaccggata tggctcctgg gcagagttat
5221 caaccccaat cagaatctgc ttcctctagt tcgatggata agtatcatat acatcacatt
5281 tctgaaccaa ctagacaaga aaactggaca cctttgaaaa atgacttgga aaatcacctt
5341 gaagactttg aactggaagt agaactcctc attaccctaa ttaaatcaga aaaaggaagc
5401 ctgggtttta cagtaaccaa aggcaatcag agaattggtt gttatgttca tgatgtcata
5461 caggatccag ccaaaagtga tggaaggcta aaacctgggg accggctcat aaaggttaat
5521 gatacagatg ttactaatat gactcataca gatgcagtta atctgctccg ggctgcatcc
5581 aaaacagtca gattagttat tggacgagtt ctagaattac ccagaatacc aatgttgcct
5641 catttgctac cggacataac actaacgtgc aacaaagagg agttgggttt ttccttatgt
5701 ggaggtcatg acagccttta tcaagtggta tatattagtg atattaatcc aaggtccgtc
5761 gcagccattg agggtaatct ccagctatta gatgtcatcc attatgtgaa cggagtcagc
5821 acacaaggaa tgaccttgga ggaagttaac agagcattag acatgtcact tccttcattg
5881 gtattgaaag caacaagaaa tgatcttcca gtggtcccca gctcaaagag gtctgctgtt
5941 tcagctccaa agtcaaccaa aggcaatggt tcctacagtg tggggtcttg cagccagcct
6001 gccctcactc ctaatgattc attctccacg gttgctgggg aagaaataaa tgaaatatcg
6061 taccccaaag gaaaatgttc tacttatcag ataaagggat caccaaactt gactctgccc
6121 aaagaatctt atatacaaga agatgacatt tatgatgatt cccaagaagc tgaagttatc
6181 cagtctctgc tggatgttgt ggatgaggaa gcccagaatc ttttaaacga aaataatgca
6241 gcaggatact cctgtggtcc aggtacatta aagatgaatg ggaagttatc agaagagaga
6301 acagaagata cagactgcga tggttcacct ttacctgagt attttactga ggccaccaaa
6361 atgaatggct gtgaagaata ttgtgaagaa aaagtaaaaa gtgaaagctt aattcagaag
6421 ccacaagaaa agaagactga tgatgatgaa ataacatggg gaaatgatga gttgccaata
6481 gagagaacaa accatgaaga ttctgataaa gatcattcct ttctgacaaa cgatgagctc
6541 gctgtactcc ctgtcgtcaa agtgcttccc tctggtaaat acacgggtgc caacttaaaa
6601 tcagtcattc gagtcctgcg gggtttgcta gatcaaggaa ttccttctaa ggagctggag
6661 aatcttcaag aattaaaacc tttggatcag tgtctaattg ggcaaactaa ggaaaacaga
6721 aggaagaaca gatataaaaa tatacttccc tatgatgcta caagagtgcc tcttggagat
6781 gaaggtggct atatcaatgc cagcttcatt aagataccag ttgggaaaga agagttcgtt
6841 tacattgcct gccaaggacc actgcctaca actgttggag acttctggca gatgatttgg
6901 gagcaaaaat ccacagtgat agccatgatg actcaagaag tagaaggaga aaaaatcaaa
6961 tgccagcgct attggcccaa catcctaggc aaaacaacaa tggtcagcaa cagacttcga
7021 ctggctcttg tgagaatgca gcagctgaag ggctttgtgg tgagggcaat gacccttgaa
7081 gatattcaga ccagagaggt gcgccatatt tctcatctga atttcactgc ctggccagac
7141 catgatacac cttctcaacc agatgatctg cttactttta tctcctacat gagacacatc
7201 cacagatcag gcccaatcat tacgcactgc agtgctggca ttggacgttc agggaccctg
7261 atttgcatag atgtggttct gggattaatc agtcaggatc ttgattttga catctctgat
7321 ttggtgcgct gcatgagact acaaagacac ggaatggttc agacagagga tcaatatatt
7381 ttctgctatc aagtcatcct ttatgtcctg acacgtcttc aagcagaaga agagcaaaaa
7441 cagcagcctc agcttctgaa gtgacatgaa aagagcctct ggatgcattt ccatttctct
7501 ccttaacctc cagcagactc ctgctctcta tccaaaataa agatcacaga gcagcaagtt
7561 catacaacat gcatgttctc ctctatctta gaggggtatt cttcttgaaa ataaaaaata
7621 ttgaaatgct gtatttttac agctacttta acctatgata attatttaca aaattttaac
7681 actaaccaaa caatgcagat cttagggatg attaaaggca gcatttgatg atagcagaca
7741 ttgttacaag gacatggtga gtctattttt aatgcaccaa tcttgtttat agcaaaaatg
7801 ttttccaata ttttaataaa gtagttattt tataggggat acttgaaacc agtatttaag
7861 ctttaaatga cagtaatatt ggcatagaaa aaagtagcaa atgtttactg tatcaatttc
7921 taatgtttac tatatagaat ttcctgtaat atatttatat actttttcat gaaaatggag
7981 ttatcagtta tctgtttgtt actgcatcat ctgtttgtaa tcattatctc actttgtaaa
8041 taaaaacaca ccttaaaaca tg
//