LOCUS HUMGULOA 644 bp DNA linear HUM 13-FEB-2003 DEFINITION Homo sapiens GULO gene for L-gulono-gamma-lactone oxidase, exon 7. ACCESSION D17460 VERSION D17460.1 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 644) AUTHORS Nishikimi,M. TITLE Direct Submission JOURNAL Submitted (23-AUG-1993) to the DDBJ/EMBL/GenBank databases. Contact:Morimitsu Nishikimi Wakayama Medical College, Dept. of Biochemistry; 27 Kyubancho, Wakayama, Wakayama 640, Japan REFERENCE 2 AUTHORS Nishikimi,M., Koshizaka,T., Ozawa,T. and Yagi,K. TITLE Occurrence in humans and guinea pigs of the gene related to their missing enzyme L-gulono-gamma-lactone oxidase JOURNAL Arch. Biochem. Biophys. 267, 842-846 (1988) REFERENCE 3 AUTHORS Nishikimi,M., Fukuyama,R., Minoshima,S., Shimizu,N. and Yagi,K. TITLE Cloning and chromosomal mapping of the human nonfunctional gene L-gulono-.gamma.-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man JOURNAL J. Biol. Chem. 269, 13685-13688 (1994) COMMENT FEATURES Location/Qualifiers source 1..644 /chromosome="8" /clone="lambda HGO8" /clone_lib="lambda phage, EMBL4" /db_xref="taxon:9606" /mol_type="genomic DNA" /organism="Homo sapiens" /tissue_type="peripheral blood" exon 528..634 /EC_number="1.1.3.8" /gene="GULO" /note="biosynthesis of L-ascorbic acid" /note="flavin enzyme" /number=7 /product="L-gulono-gamma-lactone oxidase" BASE COUNT 180 a 174 c 123 g 167 t ORIGIN 1 ctgcagtgag ctaagatcgt gccactgcac tccagcctgg gtgacagagc aagacagccc 61 ttttaaagaa aaagaataat agcactagaa gcagtagctg atgcctatat attgcttgcc 121 atgtgcctga ccattttaaa caccttctag gccttagctc atttactctc cataacaatc 181 ctgacgtgga tactgttatt aaccccattt tacagatgag gcacttgagg cccagagaca 241 ttagataact tgcccaaact cacacagcta gtacttgctc aagccaggac aaagaagaaa 301 tcacttctgt cctctaaact actcggggaa gtcatcatgt aagtggacca tttgaatgcc 361 cagcatctta taaaactcat tccatgctat ttgcaatgtt atgacatctt taagtatttc 421 cttttgatga agaagaaact gaggcacacc catgccctgg cttccattac tcgcatcacc 481 ttcctatggc caatgtagcc tctccctttt cctcctgctg aggtcagttc ctccatagcc 541 tggacagcat tggaagaaat ctgaggactt ctgcttcctc tggttcccac acagtgagaa 601 cgtcagtgcc atccaccagg accacaccag caaggcagct gcag //