LOCUS HUMHTPA 2690 bp mRNA linear HUM 07-JUN-2003
DEFINITION Homo sapiens mRNA for mitochondrial enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenese alpha-subunit of
trifunctional protein, complete cds.
ACCESSION D16480
VERSION D16480.1
KEYWORDS 3-hydroxyacyl-CoA dehydrogenase alpha-subunit; enoyl-CoA
hydratase; trifunctional protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2690)
AUTHORS Kamijo,T.
TITLE Direct Submission
JOURNAL Submitted (17-JUN-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Takehiko Kamijo
Shinshu University School of Medicine, Pediatric Department; Asahi
3-1-1, Matsumoto, Nagano 390, Japan
REFERENCE 2
AUTHORS Kamijo,T., Aoyama,T., Komiyama,A. and Hashimoto,T.
TITLE Structural analysis of cDNAs for subunits of human mitochondorial
fatty acid beta-oxidation trifunctional protein
JOURNAL Biochem. Biophys. Res. Commun. 199, 818-825 (1994)
COMMENT
FEATURES Location/Qualifiers
source 1..2690
/clone="Halpha-[1, 2 and 3]"
/clone_lib="lambda gt11"
/db_xref="H-InvDB:HIT000100598"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 28..2319
/codon_start=1
/EC_number="1.1.1.35"
/EC_number="4.2.1.17"
/gene="HTP-alpha"
/product="enoyl-CoA hydratase/3-hydroxyacyl-CoA
dehydrogenase alpha-subunit of trifunctional protein"
/protein_id="BAA03941.1"
/translation="MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYG
VKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGA
DINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCVGGGLEVAISCQYRI
ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV
DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIP
FVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTK
ESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDA
TLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFE
DLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQL
LEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGV
DPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVS
KGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFV
NEAVMCLQEGISATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAY
GKQFTPCQLLADHANSPNKKFYQ"
sig_peptide 28..135
mat_peptide 136..2316
/product="enoyl-CoA hydratase/3-hydroxyacyl-CoA
dehydrogenase alpha-subunit of trifunctional protein"
BASE COUNT 753 a 602 c 706 g 629 t
ORIGIN
1 aaaaactgct gtcctcttca gctcaagatg gtggcctgcc gggcgattgg catcctcagc
61 cgcttttctg ccttcaggat cctccgctcc cgaggttata tatgccgcaa ttttacaggg
121 tcttctgctt tgctgaccag aacccatatt aactatggag tcaaagggga tgtggcagtt
181 gttcgaatta actctcccaa ttcaaaggta aatacactga gtaaagagct acattcagag
241 ttctcagaag ttatgaatga aatctgggct agtgatcaaa tcagaagtgc cgtccttatc
301 tcatcaaagc caggctgctt tattgcaggt gctgatatca acatgttagc cgcttgcaag
361 acccttcaag aagtaacaca gctatcacaa gaagcacaga gaatagttga gaaacttgaa
421 aagtccacaa agcctattgt ggctgccatc aatggatcct gcgtgggagg aggacttgag
481 gttgccattt catgccaata cagaatagca acaaaagaca gaaaaacagt attaggtacc
541 cctgaagttt tgctgggggc cttaccagga gcaggaggca cacaaaggct gcccaaaatg
601 gtgggtgtgc ctgctgcttt ggacatgatg ctgactggta gaagcattcg tgcagacagg
661 gcaaagaaaa tgggactggt tgaccaactg gtggaacccc tgggaccagg actaaaacct
721 ccagaggaac ggacaataga atacctagaa gaagttgcaa ttacttttgc caaaggacta
781 gctgataaga agatctctcc aaagagagac aagggattgg tggaaaaatt gacagcgtat
841 gccatgacta ttccatttgt caggcaacag gtttacaaaa aagtggaaga aaaagtgcga
901 aagcagacta aaggccttta tcctgcacct ctgaaaataa ttgatgtggt aaagactgga
961 attgagcaag ggagtgatgc cggttatctc tgtgaatctc agaaatttgg agagcttgta
1021 atgaccaaag aatcaaaggc cttgatggga ctctaccatg gtcaggtcct gtgcaagaag
1081 aataaatttg gagctccaca gaaggatgtt aagcatctgg ctattcttgg tgcagggctg
1141 atgggagcag gcatcgccca agtctccgtg gataaggggc taaagactat acttaaagat
1201 gccaccctca ctgcgctaga ccgaggacag caacaagtgt tcaaaggatt gaatgacaaa
1261 gtgaagaaga aagctctaac atcatttgaa agggattcca tcttcagcaa cttgactggg
1321 cagcttgatt accaaggttt tgaaaaggcc gacatggtga ttgaagctgt gtttgaggac
1381 cttagtctta agcacagagt gctaaaggaa gtagaagcgg tgattccaga tcactgtatc
1441 tttgccagta acacatctgc tctcccaatc agtgaaatcg ctgctgtcag caaaagacct
1501 gagaaggtga ttggcatgca ctacttctct cccgtggaca agatgcagct gctggagatt
1561 atcacgaccg agaaaacttc caaagacacc agtgcttcag ctgtagcagt tggtctcaag
1621 caggggaagg tcatcattgt ggttaaggat ggacctggct tctatactac caggtgtctt
1681 gcgcccatga tgtctgaagt catccgaatc ctccaggaag gagttgaccc gaagaagctg
1741 gattccctga ccacaagctt tggctttcct gtgggtgccg ccacactggt ggatgaagtt
1801 ggtgtggatg tagcgaaaca tgtggcggaa gatctgggca aagtctttgg ggagcggttt
1861 ggaggtggaa acccagaact gctgacacag atggtgtcca agggcttcct aggtcgtaaa
1921 tctgggaagg gcttttacat ctatcaggag ggtgtgaaga ggaaggattt gaattctgac
1981 atggatagta ttttagcgag tctgaagctg cctcctaagt ctgaagtctc atcagacgaa
2041 gacatccagt tccgcctggt gacaagattt gtgaatgagg cagtcatgtg cctgcaagag
2101 gggatctcgg ccacacctgc agagggagac atcggagccg tctttgggct tggcttcccg
2161 ccttgtctgg gagggccttt ccgctttgtg gatctgtatg gcgcccagaa gatagtggac
2221 cggctcaaga aatatgaagc tgcctatgga aaacagttca ccccatgcca gctgctagct
2281 gaccatgcta acagccctaa caagaagttc taccagtgag caggcctcat gcctcgctca
2341 gtcagtgcac taaccccagc tgccggcagt gctggttctc caacagagtg gtgtctagat
2401 ttatcagagt aacgagaaga caaactccgg cactgggttt gctccctgat taaagtgcct
2461 tcagccaaga ccatctctcc ctcctggtga agtgtgactt cgaattagtt tgcacttcct
2521 attggaaggt agagcccact gctcattgta taagccccga ggcctagagt ggcagccaag
2581 agccatctga agccacctct ctgcctgttc ctcccaagag gccagggtgg ccaggggtgg
2641 tgagggcagt tctgcaccca gccaaacaca taacaataaa aaccaaactc
//