LOCUS HUMDSAEC 1584 bp mRNA linear HUM 13-FEB-2003
DEFINITION Homo sapiens mRNA for mitochondrial 3-oxoacyl-CoA thiolase,
complete cds.
ACCESSION D16294
VERSION D16294.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1584)
AUTHORS Ohtake,A.
TITLE Direct Submission
JOURNAL Submitted (19-MAY-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Akira Ohtake
The Tokyo Metropolitan institute of Medical Science, Department of
Clinical Genetics; 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113, Japan
REFERENCE 2
AUTHORS Abe,H., Ohtake,A., Yamamoto,S., Satoh,Y., Takayanagi,M., Amaya,Y.,
Takiguchi,M., Sakuraba,H., Suzuki,Y., Mori,M. and Niimi,H.
TITLE Cloning and sequence analysis of a full length cDNA encoding human
mitochondrial 3-oxoacyl-CoA thiolase
JOURNAL Biochim. Biophys. Acta 1216, 304-306 (1993)
COMMENT
FEATURES Location/Qualifiers
source 1..1584
/db_xref="H-InvDB:HIT000100577"
/db_xref="taxon:9606"
/mol_type="mRNA"
/note="clones hT1-[1, 2, 3]"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 49..1242
/codon_start=1
/EC_number="2.3.1.16"
/note="mitochondrial fatty acid oxidation"
/product="mitochondrial 3-oxoacyl-CoA thiolase"
/protein_id="BAA03800.1"
/translation="MRLLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAG
KVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNG
CQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLP
MAMTAENLTVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQ
VDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPL
ARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSL
DLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVI
IQSTA"
mat_peptide 49..1239
/product="mitochondrial 3-oxoacyl-CoA thiolase"
misc_feature 49..96
/note="non-cleavable mitochondrial targeting signal"
regulatory 1564..1569
/regulatory_class="polyA_signal_sequence"
polyA_site 1584
BASE COUNT 455 a 336 c 389 g 404 t
ORIGIN
1 gcgtccccca caccacagac ccgcgccgcc gacgacccag cagccgccat gcgtctgctc
61 cgaggtgtgt ttgtagttgc tgctaagcga acgccctttg gagcttacgg aggccttctg
121 aaagacttca ctgctactga cttgtctgaa tttgctgcca aggctgcctt gtctgctggc
181 aaagtctcac ctgaaacagt tgacagtgtg attatgggca atgtcctgca gagttcttca
241 gatgctatat atttggcaag gcatgttggt ttgcgtgtgg gaatcccaaa ggagacccca
301 gctctcacga ttaataggct ctgtggttct ggttttcagt ccattgtgaa tggatgtcag
361 gaaatttgtg ttaaagaagc tgaagttgtt ttatgtggag gaaccgaaag catgagccaa
421 gctccctact gtgtcagaaa tgtgcgtttt ggaaccaagc ttggatcaga tatcaagctg
481 gaagattctt tatgggtatc attaacagat cagcatgtcc agctccccat ggcaatgact
541 gcagagaatc ttactgtaaa acacaaaata agcagagaag aatgtgacaa atatgccctg
601 cagtcacagc agagatggaa agctgctaat gatgctggct actttaatga tgaaatggca
661 ccaattgaag tgaagacaaa gaaaggaaaa cagacaatgc aggtagacga gcatgctcgg
721 ccccaaacca ccctggaaca gttacagaaa cttcctccag tattcaagaa agatggaact
781 gttactgcag ggaatgcatc gggtgtagct gatggtgctg gagctgttat catagctagt
841 gaagatgctg ttaagaaaca taacttcaca ccactggcaa gaattgtggg ctactttgta
901 tctggatgtg atccctctat catgggtatt ggtcctgtcc ctgctatcag tggggcactg
961 aagaaagcag gactgagtct taaggacatg gatttggtag aggtgaatga agcttttgct
1021 ccccagtact tggctgttga gaggagtttg gatcttgaca taagtaaaac caatgtgaat
1081 ggaggagcca ttgctttggg tcacccactg ggaggatctg gatcaagaat tactgcacac
1141 ctggttcacg aattaaggcg tcgaggtgga aaatatgccg ttggatcagc ttgcattgga
1201 ggtggccaag gtattgctgt catcattcag agcacagcct gaagagacca gtgagctcac
1261 tgtgacccat ccttactcta cttggccagg ccacagtaaa acaagtgacc ttcagagcag
1321 ctgccacaac tggccatgcc ctgccattga aacagtgatt aagtttgatc aagccatggt
1381 gacacaaaaa tgcattgatc atgaatagga gcccatgcta gaagtacatt ctctcagatt
1441 tgaaccagtg aaatatgatg tatttctgag ctaaaactca actatagaag acattaaaag
1501 aaatcgtatt cttgccaagt aaccaccact tctgccttag ataatatgat tataaggaaa
1561 tcaaataaat gttgccttaa cttc
//