LOCUS HUMAPAA 1449 bp mRNA linear HUM 27-SEP-2007
DEFINITION Homo sapiens mRNA for adrenomedullin precursor, complete cds.
ACCESSION D14874
VERSION D14874.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1449)
AUTHORS Kitamura,K., Sakata,J., Kangawa,K., Kojima,M., Matsuo,H. and Eto,T.
TITLE Direct Submission
JOURNAL Submitted (29-MAR-1993) to the DDBJ/EMBL/GenBank databases.
Contact:Kazuo Kitamura
Miyazaki Medical College, Department of First Internal Medicine;
5200 Kihara, Kiyotake, Miyazaki, Miyazaki 889-16, Japan
REFERENCE 2
AUTHORS Kitamura,K., Sakata,J., Kangawa,K., Kojima,M., Matsuo,H. and Eto,T.
TITLE Cloning and characterization of cDNA encoding a precursor for
human adrenomedullin
JOURNAL Biochem. Biophys. Res. Commun. 194, 720-725 (1993)
COMMENT
FEATURES Location/Qualifiers
source 1..1449
/clone="phAM-A"
/db_xref="H-InvDB:HIT000100562"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="pheochromocytoma"
misc_difference 1
/citation=[2]
/replace="ggcacgagc"
CDS 157..714
/codon_start=1
/product="adrenomedullin precursor"
/protein_id="BAA03589.1"
/translation="MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKR
ELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNF
QGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPG
RTLVSSKPQAHGAPAPPSGSAPHFL"
sig_peptide 157..219
mat_peptide 220..711
/product="pro-adrenomedullin"
mat_peptide 439..594
/experiment="experimental evidence, no additional details
recorded"
/product="adrenomedullin"
polyA_site 1449
BASE COUNT 319 a 394 c 415 g 321 t
ORIGIN
1 ctggatagaa cagctcaagc cttgccactt cgggcttctc actgcagctg ggcttggact
61 tcggagtttt gccattgcca gtgggacgtc tgagactttc tccttcaagt acttggcaga
121 tcactctctt agcagggtct gcgcttcgca gccgggatga agctggtttc cgtcgccctg
181 atgtacctgg gttcgctcgc cttcctaggc gctgacaccg ctcggttgga tgtcgcgtcg
241 gagtttcgaa agaagtggaa taagtgggct ctgagtcgtg ggaagaggga actgcggatg
301 tccagcagct accccaccgg gctcgctgac gtgaaggccg ggcctgccca gacccttatt
361 cggccccagg acatgaaggg tgcctctcga agccccgaag acagcagtcc ggatgccgcc
421 cgcatccgag tcaagcgcta ccgccagagc atgaacaact tccagggcct ccggagcttt
481 ggctgccgct tcgggacgtg cacggtgcag aagctggcac accagatcta ccagttcaca
541 gataaggaca aggacaacgt cgcccccagg agcaagatca gcccccaggg ctacggccgc
601 cggcgccggc gctccctgcc cgaggccggc ccgggtcgga ctctggtgtc ttctaagcca
661 caagcacacg gggctccagc ccccccgagt ggaagtgctc cccactttct ttaggattta
721 ggcgcccatg gtacaaggaa tagtcgcgca agcatcccgc tggtgcctcc cgggacgaag
781 gacttcccga gcggtgtggg gaccgggctc tgacagccct gcggagaccc tgagtccggg
841 aggcaccgtc cggcggcgag ctctggcttt gcaagggccc ctccttctgg gggcttcgct
901 tccttagcct tgctcaggtg caagtgcccc agggggcggg gtgcagaaga atccgagtgt
961 ttgccaggct taaggagagg agaaactgag aaatgaatgc tgagaccccc ggagcagggg
1021 tctgagccac agccgtgctc gcccacaaac tgatttctca cggcgtgtca ccccaccagg
1081 gcgcaagcct cactattact tgaactttcc aaaacctaaa gaggaaaagt gcaatgcgtg
1141 ttgtacatac agaggtaact atcaatattt aagtttgttg ctgtcaagat tttttttgta
1201 acttcaaata tagagatatt tttgtacgtt atatattgta ttaagggcat tttaaaagca
1261 attatattgt cctcccctat tttaagacgt gaatgtctca gcgaggtgta aagttgttcg
1321 ccgcgtggaa tgtgagtgtg tttgtgtgca tgaaagagaa agactgatta cctcctgtgt
1381 ggaagaagga aacaccgagt ctctgtataa tctatttaca taaaatgggt gatatgcgaa
1441 cagcaaacc
//