LOCUS HUMMEL18 2227 bp mRNA linear HUM 26-SEP-2008
DEFINITION Homo sapiens mRNA for Mel-18 protein, complete cds.
ACCESSION D13969
VERSION D13969.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2227)
AUTHORS Ishida,A.
TITLE Direct Submission
JOURNAL Submitted (21-DEC-1992) to the DDBJ/EMBL/GenBank databases.
Contact:Atsushi Ishida
School of Medicine, Chiba University, Division of Molecular
Immunology; 1-8-1 Inohana, Chuo-ku, Chiba, Chiba 260, Japan
REFERENCE 2
AUTHORS Ishida,A., Asano,H., Hasegawa,M., Koseki,H., Ono,T., Yoshida,M.,
Taniguchi,M. and Kanno,M.
TITLE Cloning and chromosome mapping of the human Mel-18 gene which
encodes a DNA-binding protein with a new 'RING-finger' motif
JOURNAL Gene 129, 249-255 (1993)
COMMENT
FEATURES Location/Qualifiers
source 1..2227
/cell_type="T-cell"
/chromosome="12"
/clone_lib="lambda gt11 library of M. Yoshida"
/db_xref="H-InvDB:HIT000100527"
/db_xref="taxon:9606"
/map="12q22"
/mol_type="mRNA"
/note="HTLV transformed HUT102"
/note="clones 1 and 4"
/organism="Homo sapiens"
CDS 202..1236
/codon_start=1
/note="bmi-1"
/note="polycomb group gene"
/note="zinc-finger"
/product="Mel-18 protein"
/protein_id="BAA03074.1"
/translation="MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIV
RYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYP
LTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEK
TGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWR
RNGPLPLKYRVQPACKRLTLATVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSL
PSPATPSHGSPSSHGPPATHPTSPTPPSTASGATTAANGGSLNCLQTPSSTSRGRKMT
VNGAPVPPLT"
regulatory 1364..1369
/regulatory_class="polyA_signal_sequence"
regulatory 1576..1581
/regulatory_class="polyA_signal_sequence"
BASE COUNT 489 a 659 c 568 g 511 t
ORIGIN
1 gagagcccga acaggaagag ggtacagctt tgtgcaggtc acatgcccac tgcagccctc
61 cagcctctgg tccccagagc ggactttgga agctgaactg cttttgttgc tggaagactt
121 atgttataat ttaccctggg tggaccaggg tcgtacaaaa gggcaacgct ccccagtccc
181 cccactcccg accccggaat catgcatcgg actacacgga tcaaaatcac agagctgaac
241 ccccacctca tgtgtgccct ctgcgggggg tacttcatcg acgccaccac tatcgtggag
301 tgcctgcatt ccttctgcaa aacctgcatc gtgcgctacc tggagaccaa caaatactgc
361 cccatgtgtg acgtgcaggt ccataaaacc cggccgctgc tgagcatcag gtctgacaaa
421 acacttcaag acattgtcta caaattggtc cctgggcttt ttaaagatga gatgaaacgg
481 cggcgggatt tctatgcagc gtaccccctg acggaggtcc ccaacggctc caatgaggac
541 cgcggcgagg tcttggagca ggagaagggg gctctgagtg atgatgagat tgtcagcctc
601 tccatcgaat tctacgaagg tgccagggac cgggatgaga agaagggccc cctggagaat
661 ggggatgggg acaaagagaa aacaggggtg cgcttcctgc gatgcccagc agccatgacc
721 gtcatgcatc ttgccaagtt tctccgcaac aagatggatg tgcccagcaa gtacaaggtg
781 gaggttctgt acgaggacga gccactgaag gaatactaca ccctcatgga catcgcctac
841 atctacccct ggcggcggaa cgggcctctc cccctcaagt accgtgtcca gccagcctgc
901 aagcggctca ccctagccac ggtgcccacc ccctccgagg gcaccaacac cagcggggcg
961 tccgagtgtg agtcagtcag cgacaaggct cccagccctg ccaccctgcc agccacctcc
1021 tcctccctgc ccagcccagc caccccatcc catggctctc ccagttccca tgggcctcca
1081 gccacccacc ctacctcccc cactccccct tcgacagcca gtggggccac cacagctgcc
1141 aacgggggta gcttgaactg cctgcagaca ccatcctcca ccagcagggg gcgcaagatg
1201 actgtcaacg gcgctcccgt gcccccctta acttgaggcc agggaccctc tcccttcttc
1261 cagccaagcc tctccactcc ttccactttt tctgggccct tttttccact tcttctactt
1321 tccccagctc ttcccacctt gggggtgggg ggcgggtttt ataaataaat atatatatat
1381 atgtacatag gaaaaaccaa atatacatac ttattttcta tggaccaacc agattaattt
1441 aaatgccaca ggaaacaaac tttatgtgtg tgtgtatgtg tggaaaatgg tgttcatttt
1501 ttttgggggg ggtcttgtgt aatttgctgt ttttgggggt gcctggagat gaactggatg
1561 ggccactgga gtctcaataa agctctgcac catcctcgct gtttcccaag gcaggtggtg
1621 tgttgggggc cccttcagac ccaaagcttt aggcatgatt ccaactggct gcatatagga
1681 gtcagttaga attgtttctt tctctccccg tttctctccc catcttggct gctgtcctgc
1741 ctctgaccag tggccgcccc ccgcgttgtt gaatgtccag aaattgctaa gaacagtgcc
1801 ttttacaaat gcagtttatc cctggttctg aggagcaagt gcagggtgga ggtggcacct
1861 gcatcacctc ctcctcttgc agtggaaact ttgtgcaaag aatagatagt tctgcctctt
1921 tttttttttt ttcctgtgtg tgtggccttt gcatcattta tcttgtggaa aagaagattc
1981 aggccctgag aggtctcagc tcttggagga gggctaaggc tttagcattg tgaagcgctg
2041 cacccccacc aaccttaccc tcaccgggga accctcacta gcaggactgg tggtggagtc
2101 tcacctgggg cctagagtgg aagtgggggt gggttaacct cacacaagca cagatcccag
2161 actttgccag aggcaaacag ggaattccgc cgatactgac gggctccagg agtcgtcgcc
2221 acactcg
//