LOCUS HUMXDHA 4404 bp mRNA linear HUM 12-MAY-2009
DEFINITION Homo sapiens Xdha mRNA for xanthine dehydrogenase, complete cds.
ACCESSION D11456
VERSION D11456.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4404)
AUTHORS Ichida,K.
TITLE Direct Submission
JOURNAL Submitted (17-JUN-1992) to the DDBJ/EMBL/GenBank databases.
Contact:Kimiyoshi Ichida
Jikei University School of Medicine, Department of Internal
Medicine, Division of Nephrology and Hypertension; 3-25-8
Nishishimbashi, Minato-ku, Tokyo 105-8461, Japan
REFERENCE 2
AUTHORS Ichida,K., Amaya,Y., Noda,K., Minoshima,S., Hosoya,T., Sakai,O.,
Shimizu,N.S. and Nishino,T.
TITLE Cloning of the cDNA encoding human xanthine dehydrogenase
(oxidase):structural analysis of the protein and chromosomal
location of the gene
JOURNAL Gene 133, 279-284 (1993)
COMMENT
FEATURES Location/Qualifiers
source 1..4404
/db_xref="H-InvDB:HIT000100448"
/db_xref="taxon:9606"
/dev_stage="adult"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 58..4059
/codon_start=1
/EC_number="1.17.1.4"
/gene="Xdha"
/product="xanthine dehydrogenase"
/protein_id="BAA02013.2"
/translation="MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCG
EGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQ
ERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGF
RTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLR
LKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP
MIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQL
RWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPG
YRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQ
ELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFR
CTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPK
GQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTS
EAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRA
AQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQ
EHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGG
FGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGT
VVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRG
FGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEEC
LASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSV
LLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNG
QAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETN
SGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGL
GLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGE
PPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT
GVPENCKPWSVRV"
BASE COUNT 1120 a 1119 c 1197 g 968 t
ORIGIN
1 cgaattccgt ctcttaggag tgaggtacct ggagttcggg gaccccaacc tgtgacaatg
61 acagcagaca aattggtttt ctttgtgaat ggcagaaagg tggtggagaa aaatgcagat
121 ccagagacaa cccttttggc ctacctgaga agaaagttgg ggctgagtgg aaccaagctc
181 ggctgtggag aggggggctg cggggcttgc acagtgatgc tctccaagta tgatcgtctg
241 cagaacaaga tcgtccactt ttctgccaat gcctgcctgg cccccatctg ctccttgcac
301 catgttgcag tgacaactgt ggaaggaata ggaagcacca agacgaggct gcatcctgtg
361 caggagagaa ttgccaaaag ccacggctcc cagtgcgggt tctgcacccc tggcatcgtc
421 atgagtatgt acacactgct ccggaatcag cccgagccca ccatggagga gattgagaat
481 gccttccaag gaaatctgtg ccgctgcaca ggctacagac ccatcctcca gggcttccgg
541 acctttgcca gggatggtgg atgctgtgga ggagatggga ataatccaaa ttgctgcatg
601 aaccagaaga aagaccactc agtcagcctc tcgccatctt tattcaaacc agaggagttc
661 acgcccctgg atccaaccca ggagcccatt tttcccccag agttgctgag gctgaaagac
721 actcctcgga agcagctgcg atttgaaggg gagcgtgtga cgtggataca ggcctcaacc
781 ctcaaggagc tgctggacct caaggctcag caccctgacg ccaagctggt cgtggggaac
841 acggagattg gcattgagat gaagttcaag aatatgctgt ttcctatgat tgtctgccca
901 gcctggatcc ctgagctgaa ttcggtagaa catggacccg acggtatctc ctttggagct
961 gcttgccccc tgagcattgt ggaaaaaacc ctggtggatg ctgttgctaa gcttcctgcc
1021 caaaagacag aggtgttcag aggggtcctg gagcagctgc gctggtttgc tgggaagcaa
1081 gtcaagtctg tggcgtccgt tggagggaac atcatcactg ccagccccat ctccgacctc
1141 aaccccgtgt tcatggccag tggggccaag ctgacacttg tgtccagagg caccaggaga
1201 actgtccaga tggaccacac cttcttccct ggctacagaa agaccctgct gagcccggag
1261 gagatactgc tctccataga gatcccctac agcagggagg gggagtattt ctcagcattc
1321 aagcaggcct cccggagaga agatgacatt gccaaggtaa ccagtggcat gagagtttta
1381 ttcaagccag gaaccacaga ggtacaggag ctggcccttt gctatggtgg aatggccaac
1441 agaaccatct cagccctcaa gaccactcag aggcagcttt ccaagctctg gaaggaggag
1501 ctgctgcagg acgtgtgtgc aggactggca gaggagctgc atctgcctcc cgatgcccct
1561 ggtggcatgg tggacttccg gtgcaccctc accctcagct tcttcttcaa gttctacctg
1621 acagtccttc agaagctggg ccaagagaac ctggaagaca agtgtggtaa actggacccc
1681 actttcgcca gtgcaacttt actgtttcag aaagaccccc cagccgatgt ccagctcttc
1741 caagaggtgc ccaagggtca gtctgaggag gacatggtgg gccggcccct gccccacctg
1801 gcagcggaca tgcaggcctc tggtgaggcc gtgtactgtg acgacattcc tcgctacgag
1861 aatgagctgt ctctccggct ggtcaccagc acccgggccc acgccaagat caagtccata
1921 gatacatcag aagctaagaa ggttccaggg tttgtttgtt tcatttccgc tgatgatgtt
1981 cctgggagta acataactgg aatttgtaat gatgagacag tctttgcgaa ggataaggtt
2041 acttgtgttg ggcatatcat tggtgctgtg gttgctgaca ccccggaaca cacacagaga
2101 gctgcccaag gggtgaaaat cacctatgaa gaactaccag ccattatcac aattgaggat
2161 gctataaaga acaactcctt ttatggacct gagctgaaga tcgagaaagg ggacctaaag
2221 aaggggtttt ccgaagcaga taatgttgtg tcaggggaga tatacatcgg tggccaagag
2281 cacttctacc tggagactca ctgcaccatt gctgttccaa aaggcgaggc aggggagatg
2341 gagctctttg tgtctacaca gaacaccatg aagacccaga gctttgttgc aaaaatgttg
2401 ggggttccag caaaccggat tgtggttcga gtgaagagaa tgggaggagg ctttggaggc
2461 aaggagaccc ggagcactgt ggtgtccacg gcagtggccc tggctgcata taagaccggc
2521 cgccctgtgc gatgcatgct ggaccgtgat gaggacatgc tgataactgg tggcagacat
2581 cccttcctgg ccagatacaa ggttggcttc atgaagactg ggacagttgt ggctcttgag
2641 gtggaccact tcagcaatgt ggggaacacc caggatctct ctcagagtat tatggaacga
2701 gctttattcc acatggacaa ctgctataaa atccccaaca tccggggcac tgggcggctg
2761 tgcaaaacca accttccctc caacacggcc ttccggggct ttggggggcc ccaggggatg
2821 ctcattgccg agtgctggat gagtgaagtt gcagtgacct gtgggatgcc tgcagaggag
2881 gtgcggagaa aaaacctgta caaagaaggg gacctgacac acttcaacca gaagcttgag
2941 ggtttcacct tgcccagatg ctgggaagaa tgcctagcaa gctctcagta tcatgctcgg
3001 aagagtgagg ttgacaagtt caacaaggag aattgttgga aaaagagagg attgtgcata
3061 attcccacca agtttggaat aagcttcaca gttccttttc tgaatcaggc aggagcccta
3121 cttcatgtgt acacagatgg ctctgtgctg ctgacccacg gggggactga gatgggccaa
3181 ggccttcata ccaaaatggt ccaggtggcc agtagagctc tgaaaatccc cacctctaag
3241 atttatatca gcgagacaag cactaacact gtgcccaaca cctctcccac ggctgcctct
3301 gtcagcgctg acctcaatgg acaggccgtc tatgcggctt gtcagaccat cttgaaaagg
3361 ctggaaccct acaagaagaa gaatcccagt ggctcctggg aagactgggt cacagctgcc
3421 tacatggaca cagtgagctt gtctgccact gggttttata gaacacccaa tctgggctac
3481 agctttgaga ctaactcagg gaaccccttc cactacttca gctatggggt ggcttgctct
3541 gaagtagaaa tcgactgcct aacaggagat cataagaacc tccgcacaga tattgtcatg
3601 gatgttggct ccagtctaaa ccctgccatt gatattggac aggtggaagg ggcatttgtc
3661 cagggccttg gcctcttcac cctagaggag ctacactatt cccccgaggg gagcctgcac
3721 acccgtggcc ctagcaccta caagatcccg gcatttggca gcatccccat tgagttcagg
3781 gtgtccctgc tccgcgactg ccccaacaag aaggccatct atgcatcgaa ggctgttgga
3841 gagccgcccc tcttcctggc tgcttctatc ttctttgcca tcaaagatgc catccgtgca
3901 gctcgagctc agcacacagg taataacgtg aaggaactct tccggctaga cagccctgcc
3961 accccggaga agatccgcaa tgcctgcgtg gacaagttca ccaccctgtg tgtcactggt
4021 gtcccagaaa actgcaaacc ctggtctgtg agggtctaaa gagagagtcc tcagcagagt
4081 cttcttgtgc tgcctttggg cttccatgga gcaggaggaa cataccacag aacatggatc
4141 tattaaagtc acagaatgac agacctgtga tttgtcaaga tgggatttgg aagacaagtg
4201 aatgcaatgg aagattttga tcaaaaatgt aatttgtaaa cacaatgata agcaaattca
4261 aaactgttat gcctaaatgg tgaatatgca attaggatca ttttctgtct gttttaatca
4321 tgtatctgga atagggtcgg gaagggtttg tgctattccc cacttactgg acagcctgta
4381 taacctcaaa aaaaaaaaaa aaaa
//