LOCUS HUMDAO 5371 bp DNA linear HUM 16-FEB-2008
DEFINITION Homo sapiens D-amino-acid oxidase gene, partial sequence.
ACCESSION D11370
VERSION D11370.1
KEYWORDS D-amino acid oxidase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5371)
AUTHORS Fukui,K.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-1992) to the DDBJ/EMBL/GenBank databases.
Contact:Kiyoshi Fukui
National Cardiovascular Center Research Institute, Department of
Biochemistry; 5-7-1 Fujishiro-dai, Suita, Osaka 565, Japan
REFERENCE 2
AUTHORS Momoi,K., Fukui,K., Watanabe,F. and Miyake,Y.
TITLE Molecular cloning and sequence analysis of cDNA encoding human
kidney D-amino acid oxidase
JOURNAL FEBS Lett. 238, 180-184 (1988)
REFERENCE 3
AUTHORS Fukui,K. and Miyake,Y.
TITLE Molecular cloning and chromosomal localization of a human gene
encoding D-amino acid oxidase
JOURNAL J. Biol. Chem. 267, 18631-18638 (1992)
COMMENT
FEATURES Location/Qualifiers
source 1..5371
/chromosome="12"
/clone_lib="EMBL-3"
/db_xref="taxon:9606"
/mol_type="genomic DNA"
/organism="Homo sapiens"
/tissue_type="Placenta"
regulatory 28..42
/note="GRE-like sequence"
/regulatory_class="other"
regulatory 103..110
/note="CRE-like sequence"
/regulatory_class="other"
misc_feature 155..166
/note="G+C rich region"
regulatory 188..195
/note="sterol-dependent repressor sequence"
/regulatory_class="other"
prim_transcript 248..>5371
/note="mRNA and introns"
exon 248..381
/note="exon U (mRNA for 5'UTR)"
intron 382..5166
/number=1
repeat_region 1327..1366
/note="dinucleotide repeats of CA"
/rpt_type=direct
repeat_region 1644..1677
/note="dinucleotide repeats of CA"
/rpt_type=direct
regulatory 2003..2010
/note="CRE-like sequence"
/regulatory_class="other"
protein_bind 2285..2292
/bound_moiety="AP-1"
regulatory 2467..2474
/note="CRE-like sequence"
/regulatory_class="other"
protein_bind 2610..2618
/bound_moiety="SP-1"
regulatory 3019..3025
/regulatory_class="TATA_box"
protein_bind 3335..3343
/bound_moiety="SP-1"
regulatory 4039..4045
/regulatory_class="TATA_box"
regulatory 4282..4288
/regulatory_class="CAAT_signal"
regulatory 4474..4481
/note="CRE-like sequence"
/regulatory_class="other"
regulatory 5048..5054
/regulatory_class="TATA_box"
exon 5167..5369
/number=1
CDS 5176..>5369
/codon_start=1
/EC_number="1.4.3.3"
/product="D-amino-acid oxidase"
/protein_id="BAA20974.1"
/translation="MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTT
TDVAAGLWQPYLSDPNNPQEA"
intron 5370..>5371
/number=2
BASE COUNT 1322 a 1325 c 1312 g 1412 t
ORIGIN
1 ggatcctctc cagctggcca gagagacaga ccttcttgtg ctcatcaacc ctccaagaat
61 gcctgccctc cctccttccc ccaaggcctg tccacagggg cttgagatca gccagaaaag
121 tcaggcaact tttcagggac tgggagcgag gtctcccggc cgggcctggg tccagtctct
181 gtgggcagtg cagtgccgag ccccacccct caagccgtgc cctgtccata gctccagact
241 ttgaccctgc actccagtcc gggctggcgg acagagggct ggaaacaaga cgctccagaa
301 tcaggagctt cccctcagga aatagcatcc tgtgtccccg cactgcagtt gtctggtctc
361 tccagcagtt tggtacttcc ggtgagtggc agatgcacct ttgagctggg gacaagggtt
421 gggagagggg agaggcaaag gatttcatgt cctcccaatg tcaaagacag ggctcaacat
481 tacagcctaa ggcaggtgac aggaaaggag agatccagcc tctcaaacat ccagcagaga
541 gaccataggt aagtgatttt tccctcccca agcctcagtt tcttcacctg gaacatgggg
601 atcataactc ccctcttaca gcgtgagtct gagtgttaaa agaggtggtg catgtaaagt
661 gcttagagca gatctaggca catagcaagt actcaaatgg tagttattat tatttttggt
721 gggggagttg gtaggctggt tctcaaactt ttatagcttc tgttccattt caaggataaa
781 ctctgcaaat aacaacttca tgagaagtag ccgtgtggtg caaccaggga gaactaatta
841 tgttcattcc aaatgcctca tctctggctt actgattttt tttttttaaa aagaagtctt
901 tcatattctt tgctatgggc acataacaat caaaggcatc agctgtctca gattgccttc
961 taggggacaa gggaggtcct aggcagataa atgcaagact gaaagacaag cagaaagcat
1021 caagtggcaa ctgcatgcca actgcctaaa tatttttttg gagcagtgca gaaagcgccg
1081 atagaactgg gtctaggtcc gaatgctgtc ccatactgac tgcgtaacct tgggtgggtg
1141 acttctcctc cctaaacctc agtctcagcc tccagaatga gggcggtaac cttccctact
1201 cctaggagag cagttgagag gattgagagg attatgtcgg tactgcatct acaggtgtct
1261 ggcaagtggc agagaccaaa atacattggt tcccttcctg ctccacactt acacagacat
1321 tctaatcaca cacacacaca cacacacaca cacacacaca cacacaaata taataatccc
1381 agctgtttgc atcttctggg atacatactc caagcttgct gggttgaagt aatgatgtaa
1441 aacagaggag aacggcaaca ctaataaaaa catcagcaac aacacgaaaa tgtccaaccg
1501 aataactgag ctgggtgcgt ttaagtccaa aagctcatta cctacacgca tgaatgattt
1561 tacctaaggc tggatctgcc acatctgaca atctgtctct ggcttgtcat gagggcctca
1621 tgcatttatt ttgtatttta aaacacacac acacacacac acacacacac acacacacgt
1681 tgctataatc agtgtcaact ttgactcata tcttgaattt ttttaaaaaa agataattga
1741 cttaggactc acactttttt ccttttaaat tttttttttt tttttttttt tttgacagag
1801 tttcactctt gtcacctggg ctggagtgca atggcatgat ttctgcccac tgcaatctcc
1861 acctcccagg ttcaagggat tctcctgcct cggcctcccg agtagctgga atttcaggcg
1921 tgcaccacca tgccaagcta atttttttgt atttttgtag agacagggtt tcaccatatt
1981 ggccaggctg gtcttgaact cctgacctca agtgatctgc cagcctcgac ctcccaaagt
2041 gctggaatta aagacgtgag ccactgtgcc cggccttttt gattttccat tctattccta
2101 ccaacactct aaaaattcct acaggcattt tattttattt tattttatct tattttatat
2161 tatattttat gtttgaaatg caggactctg aagcttcagc tgttcctatt taccggcttg
2221 attctcagat ttttcaaacc atgtgattta ctggcaagca tggcaattta agcacctagg
2281 cttatgagtc aggctgggct ggggtctgcc tctcaccacc tgggtgtcca ggagctgata
2341 ttccagtgag gagacaataa ggcaaggagc tttgtcagct ctcataaaag tttatagatg
2401 aggtcgggca tggtggctca cgcctgtaat cctagcactt tgagagtctg aggccagcaa
2461 atcacctgag gtcagaagtt tgagaccagc ctggccaaca tggtgaaact tgtctctact
2521 aaaaatacaa aaattagcca ggcatgttgg tgcatgcctg taatcccagc tactcaggag
2581 gctgaggcag gagaatcacc tgaacccagg aggcagagtc tgcagtgagc caagactgta
2641 ccattgcact ccagcctggg cgacaagagt gaaactctgt ctcgaaaaaa taaagtttat
2701 agatgaggaa actgaggttc gattaggatt aaccaactca tcctggtttg cctgggactc
2761 tgatgcactg acttttagtc tgaaagtctg catcctggga ggaccctcag tcctgggcaa
2821 gctggggagg ttggtcaccc tcactcagtc aagttgagca acttgcccag ggttacatgg
2881 ctggtgtgtg cccaagtcag gctgcgaacc tgggtctgtc tgactctcag cctgggccat
2941 actgtctctt agattcttca tggagaatta ggaaaaatac agaaagccct ttattcctct
3001 gccttctcat tgttaacata taaaaatggt caagcgggtg ggtgcagtgg cacacacctg
3061 aaagcccagc gctttgggag gctgaggggg gaggattgct tgagcctagg aattggaggt
3121 ggcagtgagc tatgattgtg ccactgcact ccagcctggg tgacagagtg agaccttgtc
3181 tctttaaaaa aaaggaaaga gtggtcagct ctccggaaat tatgcagcca gtcaaaaagc
3241 ccagagaggg gatttaactt agccaggtcg cacagcaagg cagaagtgaa gccaggtctg
3301 actctgcctt tctcttctcc tctttttttt ttttgaggca gaatttcgct ctgttgccca
3361 gactggaatg cagtggtgcg aactcgactc gctgcaacct ctgctgccca ggttcaagcg
3421 attctcctgc ctcagcctcc cgagtagctg ggattacagg cgcctgccac cgcgcctggc
3481 taatttttgt agttttcagt agagatgggg tttcaccatc ttggccagac tggtcttgaa
3541 gtcctgacct cgtgatccac ccgcctcggc ctcccaaggt attgggatta caggcgtaag
3601 caactgcagc tggtcctccc tctctccttt tgttcctgca atgtctttgt tctatgtgat
3661 ttttcaaaat gctaggagac aggaaggagg ctgctgtgtg ttgagggcct atttgtgcca
3721 gggtggtaac caagaacttt tgctaaaact tcttatttaa tccttaaaat gaccctgtga
3781 gattgggatt aaccctgttt tgcagatgaa gagcttgtgt ctccagaggc aaagtatggg
3841 ggaagaggga agagagaaga ccaagggtcc ctgagagggg ctgtcaccta agccccagta
3901 tccaagctcg ggctcgaagc tggaaggaga attgcctaga ggaacgatac ctttctgttt
3961 gttggttcta tctccaactt ggcttctgaa accccaacag agtccagttc ttgtgggctg
4021 gagccgtttt ccctccttta taaaactagg ccatattaag aatgtcccgc tgtccagggc
4081 cacaggccga tggttgccag gagctgaggt ctgcaggagg agagttgtga gtgaagagga
4141 gggaaagttg aatttggctc ttctgggcac aaataattct cttgttctgc ctcagcagga
4201 gcctgcagaa tatttccctg ctgtgcgggc ttaagtagct tcaaggttaa aagctggtag
4261 gccttctaaa cttctcaggg cccaatcagc cctgtgcccc aaggcaggtg gagttctgtg
4321 ctggaagacc aagttctgag gccagacact gcgtctgtca tgctcatagc tgcatttgct
4381 agctgccagc ctgggacatg gtagttgtgc attaagcgtg tgttgagtta ctcaaattga
4441 atcagtcaca gctgtaccat ttaactggct gtgtgacttc aggtaagtca catcacctct
4501 ctgaaccaca gtttcctcct ctgtaagacg ggactgataa cagcagcccc tacctcatga
4561 gagtgttggg agacttggat gaatggatgc ttgtgaagca cttagtgccg ggggccagct
4621 ggctcacagt aggtgctcca caaatgtcag tatattactt cttttgcatc aggcagcttg
4681 ttaaatttgt tacgtttggc atcttgttca atttcccatc catcccctca agcataggtt
4741 attagaggtt gaagcatctt gcccaaagtt aacggccagt aggtggcaga gctgagtcct
4801 gaagccagag cccatcgcac taaccaccgg cctacccagc ctacagttgg tcgtgccctc
4861 tgctgggtct tttctattcc cagcccagaa actgggtgtc tggggacgct ccccagagaa
4921 agttgcatca ttcaccagcc gtgtgactgt ggccaagtct cggtcacttc tccatacctc
4981 agtgtttcca tttgcaaaac gggaacaatg atattccttc ctcctagggg tcatcgggaa
5041 ggtcaaatat aaaaagggct tggtggtgtc tggcaccttc taagccttca gtggatggtg
5101 gcaatggcgc taaggatgat ggagatgatg gtgatgatgg tgtgcctcaa cccttccttc
5161 ccacaggctg ctgcaatgcg tgtggtggtg attggagcag gagtcatcgg gctgtccacc
5221 gccctctgca tccatgagcg ctaccactca gtcctgcagc cactggacat aaaggtctac
5281 gcggaccgct tcaccccact caccaccacc gacgtggctg ccggcctctg gcagccctac
5341 ctttctgacc ccaacaaccc acaggaggcg t
//