LOCUS HUMCAMHC 5820 bp mRNA linear HUM 19-DEC-2007
DEFINITION Homo sapiens mRNA for cardiac alpha-myosin heavy chain, complete
cds.
ACCESSION D00943
VERSION D00943.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5820)
AUTHORS Matsuoka,R.
TITLE Direct Submission
JOURNAL Submitted (12-APR-1991) to the DDBJ/EMBL/GenBank databases.
Contact:Rumiko Matsuoka
Tokyo Women's Medical College, The Heart Institute of Japan, Dept.
of Pediatric Cardiology; 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162,
Japan
REFERENCE 2
AUTHORS Matsuoka,R., Beisel,K.W., Furutani,M., Arai,S. and Takao,A.
TITLE Complete sequence of human cardiac alpha-myosin heavy chain gene
and amino acid comparison to other myosins based on structural and
functional differences
JOURNAL Am. J. Med. Genet. 41, 537-547 (1991)
COMMENT
FEATURES Location/Qualifiers
source 1..5820
/chromosome="14"
/clone="lambda-gHMHC1, CHMHC1"
/db_xref="H-InvDB:HIT000100412"
/db_xref="taxon:9606"
/map="14q11.2-q13"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="heart"
CDS 1..5820
/codon_start=1
/product="cardiac alpha-myosin heavy chain"
/protein_id="BAA00791.1"
/translation="MTDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKE
EFVKAKILSREGGKVIAETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVL
FNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDN
AYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLE
DQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF
QLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATD
SAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLN
SADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLET
KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE
WTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQK
PRNIKGKPEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLMATLFSS
YATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKA
PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDS
RKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQL
MRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKE
EFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNK
IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA
TENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLE
QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD
INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELE
EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE
LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYR
VKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQ
LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYE
TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER
SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL
EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEAS
LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSR
NEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDD
LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLI
NQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERM
KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM
RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK
VQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE"
BASE COUNT 1581 a 1506 c 1840 g 893 t
ORIGIN
1 atgaccgatg cccagatggc tgactttggg gcagcggccc agtacctccg caagtcagag
61 aaggagcgtc tagaggccca gacccggccc tttgacattc gcactgagtg cttcgtgccc
121 gatgacaagg aagagtttgt caaagccaag attttgtccc gggagggagg caaggtcatt
181 gctgaaaccg agaatgggaa gacggtgact gtgaaggagg accaggtgtt gcagcagaac
241 ccacccaagt tcgacaagat tgaggacatg gccatgctga ccttcctgca cgagcccgcg
301 gtgcttttca acctcaagga gcgctacgcg gcctggatga tatataccta ctcgggcctc
361 ttctgtgtca ctgtcaaccc ctacaagtgg ctgccggtgt acaatgccga ggtggtggcc
421 gcctaccggg gcaagaagag gagtgaggcc ccgccccaca tcttctccat ctccgacaac
481 gcctatcagt acatgctgac agatcgggag aaccagtcca tcctcatcac gggagaatcc
541 ggggcgggga agactgtgaa caccaagcgt gtcatccagt actttgccag cattgcagcc
601 ataggtgacc gtggcaagaa ggacaatgcc aatgcgaaca agggcaccct ggaggaccag
661 atcatccagg ccaaccccgc tctggaggcc ttcggcaatg ccaagactgt ccggaacgac
721 aactcctccc gctttgggaa attcattagg atccactttg gggccactgg aaagctggct
781 tctgcagaca tagagaccta cctgctggag aagtcccggg tgatcttcca gctgaaagct
841 gagagaaact accacatctt ctaccagatt ctgtccaaca agaagccgga gttgctggac
901 atgctgctgg tcaccaacaa tccctacgac tacgccttcg tgtctcaggg agaggtgtcc
961 gtggcctcca ttgatgactc cgaggagctc atggccaccg atagtgcctt tgacgtgctg
1021 ggcttcactt cagaggagaa agctggcgtc tacaagctga cgggagccat catgcactac
1081 gggaacatga agttcaagca gaagcagcgg gaggagcagg cggagccaga cggcaccgaa
1141 gatgctgaca agtctgccta cctcatgggg ctgaactcag ctgacctgct caaggggctg
1201 tgccaccctc gggtgaaagt gggcaacgag tatgtcacca aggggcagag cgtgcagcag
1261 gtttactact ccatcggggc tctggccaag gcagtgtatg agaagatgtt caactggatg
1321 gtgacgcgca tcaacgccac cctggagacc aagcagccac gccagtactt cataggagtc
1381 ctggacatcg ctggcttcga gatcttcgac ttcaacagct ttgagcagct ctgcatcaac
1441 ttcaccaacg agaagctgca gcagttcttc aaccaccaca tgttcgtgct ggagcaggag
1501 gagtacaaga aggagggcat tgagtggaca ttcattgact ttggcatgga cctgcaggcc
1561 tgcattgacc tcatcgagaa gcccatgggc atcatgtcca tcctggagga ggagtgcatg
1621 ttccccaagg ccactgacat gaccttcaag gccaagctgt acgacaacca cctgggcaag
1681 tccaacaatt tccagaagcc acgcaacatc aaggggaagc ctgaagccca cttctccctg
1741 atccactacg ccggcactgt ggactacaac atcctgggct ggctggaaaa aaacaaggat
1801 cctctcaacg agactgtcgt gggcttgtat cagaagtcct ccctcaagct catggccact
1861 ctcttctcct cctacgcaac tgccgatact ggggacagtg gtaaaagcaa aggaggcaag
1921 aaaaagggct catccttcca gacggtgtcg gctctccacc gggaaaatct caacaagcta
1981 atgaccaacc tgaggaccac ccatcctcac tttgtgcgtt gtatcatccc caatgagcgg
2041 aaggctccag gggtgatgga caaccccctg gtcatgcacc agctgcgctg caatggcgtg
2101 ctggagggca tccgcatctg caggaagggc ttccccaacc gcatcctcta cggggacttc
2161 cggcagaggt atcgcatcct gaacccagtg gccatccctg agggacagtt cattgatagc
2221 aggaaggggg cagagaagct gctcagctct ctggacattg atcacaacca gtacaagttt
2281 ggccacacca aggtgttctt caaggccggg ctgctggggc tgctggagga aatgagggac
2341 gagaggctga gccgcatcat cacgcgtatc caggcccaag cccggggcca gctcatgcgc
2401 attgagttca agaagatagt ggaacgcagg gatgccctgc tggtaatcca gtggaacatt
2461 cgggccttca tgggggtcaa gaattggccc tggatgaagc tctacttcaa gatcaagccg
2521 ctgctgaaga gcgcagagac ggagaaggag atggccacca tgaaggaaga gttcgggcgc
2581 atcaaagaga cgctggagaa gtccgaggct cgccgcaagg agctggagga gaagatggtg
2641 tccctgctgc aggagaagaa tgacctgcag ctccaagtgc aggcggaaca agacaacctc
2701 aatgatgctg aggagcgctg cgaccagctg atcaaaaaca agattcagct ggaggccaaa
2761 gtaaaggaga tgaatgagag gctggaggat gaggaggaga tgaacgcgga gctcactgcc
2821 aagaagcgca agctggaaga tgagtgctca gagctcaaga aggacattga tgacctggag
2881 ctgacactgg ccaaggtgga gaaggagaag catgcaacag agaacaaggt gaagaaccta
2941 acagaggaga tggctgggct ggatgaaatc atcgctaagc tgaccaagga gaagaaagct
3001 ctacaagagg cccatcagca ggccctggat gaccttcagg ccgaagaaga caaggtcaac
3061 accctgtcca agtctaaggt caagctggag cagcaggtgg atgatctgga gggatcccta
3121 gagcaagaga agaaggtgcg catggacctg gagcgagcaa agcggaagct ggagggtgac
3181 ttgaagctga cccaggagag catcatggac ctggaaaatg ataaactgca gctggaagaa
3241 aagcttaaga agaaggagtt tgacattaat cagcagaaca gtaagattga ggatgagcag
3301 gtgctggccc ttcaactaca gaagaaactg aaggaaaacc aggcacgcat cgaggagctg
3361 gaggaggagc tggaggccga gcgcaccgcc agggctaagg tggagaagct gcgctcagac
3421 ctgtctcggg agctggagga gatcagcgag cggctggaag aggccggcgg ggcaacgtcc
3481 gtgcagatcg agatgaacaa gaagcgcgag gccgagttcc agaagatgcg gcgggacctg
3541 gaggaggcca cgctgcagca cgaggccact gccgcggccc tgcgcaagaa gcacgccgac
3601 agcgtggccg agctgggcga gcagatcgac aacctgcagc gggtgaagca gaagctggag
3661 aaggagaaga gcgagttcaa gctggagctg gatgacgtca cctccaacat ggagcagatc
3721 atcaaggcca aggcaaacct ggagaaagtg tctcggacgc tggaggacca ggccaatgag
3781 taccgcgtga agctagaaga ggcccaacgc tccctcaatg atttcaccac ccagcgagcc
3841 aagctgcaga ccgagaatgg agagttgtcc cggcagctag aggaaaagga ggcgctaatc
3901 tcgcagctta cccgtgggaa gctctcttat acccagcaaa tggaggacct caaaaggcag
3961 ctggaggagg agggcaaggc gaagaacgcc ctggcccatg cactgcagtc ggcccggcat
4021 gactgcgacc tgctgcggga gcagtacgag gaggagacag aggccaaggc cgagctgcag
4081 cgcgtcctgt ccaaggccaa ctcggaggtg gcccagtgta ggaccaagta tgagacggac
4141 gccattcagc ggactgagga gctcgaagag gccaaaaaga agctggccca gcggctgcag
4201 gatgccgagg aggccgtgga ggctgttaat gccaagtgct cctcactgga gaagaccaag
4261 caccggctac agaatgagat agaggacttg atggtggacg tagagcgctc caatgctgct
4321 gctgcagccc tggacaagaa gcagagaaac tttgacaaga tcctggccga gtggaagcag
4381 aagtatgagg agtcgcagtc tgagctggag tcctcacaga aggaggctcg ctccctcagc
4441 acagagctct tcaagctcaa gaacgcctac gaggagtccc tggagcacct agagaccttc
4501 aagcgggaga acaagaacct tcaggaggaa atctcggacc ttactgagca gctaggagaa
4561 ggaggaaaga atgtgcatga gctggagaag gtccgcaaac agctggaggt ggagaagctg
4621 gagctgcagt cagccctgga ggaggcagag gcctccctgg agcacgagga gggcaagatc
4681 ctccgggccc agctagagtt caaccagatc aaggcagaga tcgagcggaa gctggcagag
4741 aaggacgagg agatggaaca ggccaagcgc aaccaccagc gggtggtgga ctcgctgcag
4801 acctccctgg atgcagagac acgcagccgc aacgaggtcc tgagggtgaa gaagaagatg
4861 gaaggagacc tcaatgagat ggagatccag ctcagccacg ccaaccgcat ggctgccgag
4921 gcccagaagc aagtcaagag cctccagagc ttgctgaagg acacccagat ccagctggac
4981 gatgcggtcc gtgccaacga cgacctgaag gagaacatcg ccatcgtgga gcggcgcaac
5041 aacctgctgc aggctgagct ggaggagctg cgtgccgtgg tggagcagac agagcggtcc
5101 cggaagctgg cggacaggga gctgattgag accagcgagc gggtgcagct gctgcattcc
5161 cagaacacca gcctcatcaa ccagaagaag aagatggatg ctgacctgtc ccagctccag
5221 tcggaagtgg aggaggcagt gcaggagtgc agaaacgccg aggagaaggc caagaaggcc
5281 atcacgcatg ccgccatgat ggcagaggag ctgaagaagg agcaggacac cagcgcccac
5341 ctggagcgca tgaagaagaa catggagcag accattaagg acctgcagca ccggctggac
5401 gaggccgagc agatcgccct caagggcggc aagaagcagc tgcagaagct ggaagcgcgg
5461 gtgcgggagc tggagggtga gctggaggcc gagcagaagc gcaacgcaga gtcggtgaag
5521 ggcatgagga agagcgagcg gcgcatcaag gagctcacct accagacaga ggaagacaaa
5581 aagaacctgc tgcggctaca ggacctggtg gacaagctgc aactgaaggt caaggcctac
5641 aagcgccagg ccgaggaggc ggaggagcaa gccaacacca acctgtccaa gttccgcaag
5701 gtgcagcatg agctggatga ggcagaggag cgggcggaca tcgctgagtc ccaggtcaac
5761 aagcttcgag ccaagagccg tgacattggt gccaagcaaa aaatgcacga tgaggagtga
//