LOCUS CR457338 1233 bp mRNA linear HUM 03-JUN-2004
DEFINITION Homo sapiens full open reading frame cDNA clone RZPDo834H0613D for
gene SIGIRR, single Ig IL-1R-related molecule; complete cds, incl.
stopcodon.
ACCESSION CR457338
VERSION CR457338.1
KEYWORDS Full ORF shuttle clone, Gateway(TM), complete cds.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1233)
AUTHORS Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
TITLE Cloning of human full open reading frames in Gateway(TM) system
entry vector (pDONR201)
JOURNAL Unpublished.
REFERENCE 2 (bases 1 to 1233)
AUTHORS Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
JOURNAL Submitted (03-JUN-2004) to the INSDC. RZPD Deutsches
Ressourcenzentrum fuer Genomforschung GmbH, Im Neuenheimer Feld
580, D-69120 Heidelberg, Germany
COMMENT RZPD; RZPDo834H0613D, ORFNo 2417
www.rzpd.de/cgi-bin/products/cl.cgi?CloneID=RZPDo834H0613D
RZPDLIB; Human Full ORF Clones Gateway(TM) - RZPD (kan-resist.)
RZPD LIB No. 834
www.rzpd.de/cgi-bin/products/showLib.pl.cgi/response?libNo=834
www.rzpd.de/products/orfclones/
Contact: Inge Arlart
RZPD Deutsches Ressourcenzentrum fuer Genomforschung GmbH,
Heubnerweg 6, D-14059 Berlin, Germany
Tel: +49 30 32639 100
Fax: +49 30 32639 111
www.rzpd.de
This clone is available from RZPD;
contact RZPD (customer.service@rzpd.de) for further information.
This CDS clone is a part of a collection of human full length
expression clones generated by RZPD.
This CDS has been cloned incl. stopcodon.
The CDS has been inserted into pDONR201 via a BP Clonase(TM)
reaction.
Additional sequence has been added in front of the start codon:
att..AAAAAA GCA GGC (ATG).
The last base of the last coding triplett has been changed to T,
which might lead to an amino acid change at the C terminus of the
polypeptide.
The stop codon has been set to TAA followed by
TTAACCCAGCTTTCTT..att.
Compared to the reference sequence NM_021805 we found amino acid
exchange(s) at position (first base of changed triplet):
1228(met->ile)
Clone distribution: http://www.rzpd.de/products/orfclones/
FEATURES Location/Qualifiers
source 1..1233
/db_xref="H-InvDB:HIT000268188"
/organism="Homo sapiens"
/lab_host="DH10B"
/mol_type="mRNA"
/clone_lib="Human Full ORF Clones Gateway(TM) - RZPD"
/clone="RZPDo834H0613D"
/note="Vector: pDONR201, Site_1: attP1; Site_2: attP2"
/db_xref="taxon:9606"
CDS 1..1233
/codon_start=1
/gene="SIGIRR"
/db_xref="GOA:Q6IA17"
/db_xref="H-InvDB:HIT000268188.12"
/db_xref="HGNC:HGNC:30575"
/db_xref="InterPro:IPR000157"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR015621"
/db_xref="InterPro:IPR035897"
/db_xref="InterPro:IPR036179"
/db_xref="UniProtKB/Swiss-Prot:Q6IA17"
/protein_id="CAG33619.1"
/translation="MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSL
PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQN
ISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN
DGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNL
SRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLL
RQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLIL
RGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGS
RNYSARTDFYCLVSKDDI"
BASE COUNT 204 a 408 c 378 g 243 t
ORIGIN
1 atgccaggtg tctgtgatag ggcccctgac ttcctctccc cgtctgaaga ccaggtgctg
61 aggcctgcct tgggcagctc agtggctctg aactgcacgg cttgggtagt ctctgggccc
121 cactgctccc tgccttcagt ccagtggctg aaagacgggc ttccattggg aattgggggc
181 cactacagcc tccacgagta ctcctgggtc aaggccaacc tgtcagaggt gcttgtgtcc
241 agtgtcctgg gggtcaacgt gaccagcact gaagtctatg gggccttcac ctgctccatc
301 cagaacatca gcttctcctc cttcactctt cagagagctg gccctacaag ccacgtggct
361 gcggtgctgg cctccctcct ggtcctgctg gccctgctgc tggccgccct gctctatgtc
421 aagtgccgtc tcaacgtgct gctctggtac caggacgcgt atggggaggt ggagataaac
481 gacgggaagc tctacgacgc ctacgtctcc tacagcgact gccccgagga ccgcaagttc
541 gtgaacttca tcctaaagcc gcagctggag cggcgtcggg gctacaagct cttcctggac
601 gaccgcgacc tcctgccgcg cgctgagccc tccgccgacc tcttggtgaa cctgagccgc
661 tgccgacgcc tcatcgtggt gctttcggac gccttcctga gccgggcctg gtgcagccac
721 agcttccggg agggcctgtg ccggctgctg gagctcaccc gcagacccat cttcatcacc
781 ttcgagggcc agaggcgcga ccccgcgcac ccggcgctcc gcctgctgcg ccagcaccgc
841 cacctggtga ccttgctgct ctggaggccc ggctccgtga ctccttcctc cgatttttgg
901 aaagaagtgc agctggcgct gccgcggaag gtgcggtaca ggccggtgga aggagacccc
961 cagacgcagc tgcaggacga caaggacccc atgctgattc ttcgaggccg agtccctgag
1021 ggccgggccc tggactcaga ggtggacccg gaccctgagg gcgacctggg tgtccggggg
1081 cctgtttttg gagagccatc agctccaccg cacaccagtg gggtctcgct gggagagagc
1141 cggagcagcg aagtggacgt ctcggatctc ggctcgcgaa actacagtgc ccgcacagac
1201 ttctactgcc tggtgtccaa ggatgatatt taa
//