LOCUS       CR457122                 540 bp    mRNA    linear   HUM 16-OCT-2008
DEFINITION  Homo sapiens full open reading frame cDNA clone RZPDo834H087D for
            gene FAIM, Fas apoptotic inhibitory molecule; complete cds, incl.
            stopcodon.
ACCESSION   CR457122
VERSION     CR457122.1
KEYWORDS    Full ORF shuttle clone, Gateway(TM), complete cds.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
  TITLE     Cloning of human full open reading frames in Gateway(TM) system
            entry vector (pDONR201)
  JOURNAL   Unpublished.
REFERENCE   2  (bases 1 to 540)
  AUTHORS   Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
  JOURNAL   Submitted (03-JUN-2004) to the INSDC. RZPD Deutsches
            Ressourcenzentrum fuer Genomforschung GmbH, Im Neuenheimer Feld
            580, D-69120 Heidelberg, Germany
COMMENT     RZPD; RZPDo834H087D, ORFNo 1873
            www.rzpd.de/cgi-bin/products/cl.cgi?CloneID=RZPDo834H087D
            RZPDLIB; Human Full ORF Clones Gateway(TM) - RZPD (kan-resist.)
            RZPD LIB No. 834
            www.rzpd.de/cgi-bin/products/showLib.pl.cgi/response?libNo=834
            www.rzpd.de/products/orfclones/
            Contact: Inge Arlart
            RZPD Deutsches Ressourcenzentrum fuer Genomforschung GmbH,
            Heubnerweg 6, D-14059 Berlin, Germany
            Tel: +49 30 32639 100
            Fax: +49 30 32639 111
            www.rzpd.de
            This clone is available from RZPD;
            contact RZPD (customer.service@rzpd.de) for further information.
            
            This CDS clone is a part of a collection of human full length
            expression clones generated by RZPD.
            This CDS has been cloned incl. stopcodon.
            The CDS has been inserted into pDONR201 via a BP Clonase(TM)
            reaction.
            Additional sequence has been added in front of the start codon:
            att..AAAAAA GCA GGC (ATG).
            The last base of the last coding triplett has been changed to T,
            which might lead to an amino acid change at the C terminus of the
            polypeptide.
            The stop codon has been set to TAA followed by
            TTAACCCAGCTTTCTT..att.
            Compared to the reference sequence NM_018147 we found amino acid
            exchange(s) at position (first base of changed triplet):
            196(asn->ser) 349(ala->thr)
            Clone distribution: http://www.rzpd.de/products/orfclones/
FEATURES             Location/Qualifiers
     source          1..540
                     /db_xref="H-InvDB:HIT000267972"
                     /organism="Homo sapiens"
                     /lab_host="DH10B"
                     /mol_type="mRNA"
                     /clone_lib="Human Full ORF Clones Gateway(TM) - RZPD"
                     /clone="RZPDo834H087D"
                     /note="Vector: pDONR201, Site_1: attP1; Site_2: attP2"
                     /db_xref="taxon:9606"
     CDS             1..540
                     /codon_start=1
                     /gene="FAIM"
                     /db_xref="GOA:Q9NVQ4"
                     /db_xref="H-InvDB:HIT000267972.14"
                     /db_xref="HGNC:HGNC:18703"
                     /db_xref="InterPro:IPR010695"
                     /db_xref="InterPro:IPR038513"
                     /db_xref="PDB:2KW1"
                     /db_xref="PDB:3MX7"
                     /db_xref="UniProtKB/Swiss-Prot:Q9NVQ4"
                     /protein_id="CAG33403.1"
                     /translation="MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRKEW
                     MFKLVGKETFYVGAAKTKATISIDAISGFAYEYTLEINGKSLKKYMEDRSKTTNTWVL
                     HMDGENFRIVLEKDTMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGKRK
                     EGIIHTLIVDNREIPEIAS"
BASE COUNT          191 a           70 c          142 g          137 t
ORIGIN      
        1 atgacagatc tcgtagctgt ttgggatgtt gctttaagtg acggagtcca caagatcgaa
       61 tttgaacatg ggactacatc aggcaaacga gtagtatatg tagatggaaa ggaagagata
      121 agaaaagagt ggatgttcaa attagtgggc aaagaaacat tctatgttgg agctgcaaag
      181 acaaaagcga ccataagtat agacgctatc agtggttttg cttatgaata tactctggaa
      241 attaatggga aaagtctcaa gaagtatatg gaggacagat caaaaaccac caatacttgg
      301 gtattacaca tggatggtga gaactttaga attgttttgg aaaaagatac tatggacgta
      361 tggtgcaatg gtaaaaaatt ggagacagcg ggtgagtttg tagatgatgg gactgaaact
      421 cacttcagta tcgggaacca tgactgttac ataaaggctg tcagtagtgg gaagcggaaa
      481 gaagggatta ttcatactct cattgtggat aatagagaaa tcccagagat tgcaagttaa
//