LOCUS CR456991 1554 bp mRNA linear HUM 16-OCT-2008
DEFINITION Homo sapiens full open reading frame cDNA clone RZPDo834H0211D for
gene ALDH2, aldehyde dehydrogenase 2 family (mitochondrial);
complete cds, incl. stopcodon.
ACCESSION CR456991
VERSION CR456991.1
KEYWORDS Full ORF shuttle clone, Gateway(TM), complete cds.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1554)
AUTHORS Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
TITLE Cloning of human full open reading frames in Gateway(TM) system
entry vector (pDONR201)
JOURNAL Unpublished.
REFERENCE 2 (bases 1 to 1554)
AUTHORS Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
JOURNAL Submitted (03-JUN-2004) to the INSDC. RZPD Deutsches
Ressourcenzentrum fuer Genomforschung GmbH, Im Neuenheimer Feld
580, D-69120 Heidelberg, Germany
COMMENT RZPD; RZPDo834H0211D, ORFNo 1508
www.rzpd.de/cgi-bin/products/cl.cgi?CloneID=RZPDo834H0211D
RZPDLIB; Human Full ORF Clones Gateway(TM) - RZPD (kan-resist.)
RZPD LIB No. 834
www.rzpd.de/cgi-bin/products/showLib.pl.cgi/response?libNo=834
www.rzpd.de/products/orfclones/
Contact: Inge Arlart
RZPD Deutsches Ressourcenzentrum fuer Genomforschung GmbH,
Heubnerweg 6, D-14059 Berlin, Germany
Tel: +49 30 32639 100
Fax: +49 30 32639 111
www.rzpd.de
This clone is available from RZPD;
contact RZPD (customer.service@rzpd.de) for further information.
This CDS clone is a part of a collection of human full length
expression clones generated by RZPD.
This CDS has been cloned incl. stopcodon.
The CDS has been inserted into pDONR201 via a BP Clonase(TM)
reaction.
Additional sequence has been added in front of the start codon:
att..AAAAAA GCA GGC (ATG).
The last base of the last coding triplett has been changed to T,
which might lead to an amino acid change at the C terminus of the
polypeptide.
The stop codon has been set to TAA followed by
TTAACCCAGCTTTCTT..att.
Compared to the reference sequence NM_000690 we found amino acid
exchange(s) at position (first base of changed triplet):
178(ser->phe) 1084(val->leu)
Clone distribution: http://www.rzpd.de/products/orfclones/
FEATURES Location/Qualifiers
source 1..1554
/db_xref="H-InvDB:HIT000267841"
/organism="Homo sapiens"
/lab_host="DH10B"
/mol_type="mRNA"
/clone_lib="Human Full ORF Clones Gateway(TM) - RZPD"
/clone="RZPDo834H0211D"
/note="Vector: pDONR201, Site_1: attP1; Site_2: attP2"
/db_xref="taxon:9606"
CDS 1..1554
/codon_start=1
/gene="ALDH2"
/db_xref="GOA:P05091"
/db_xref="H-InvDB:HIT000267841.12"
/db_xref="HGNC:HGNC:404"
/db_xref="InterPro:IPR015590"
/db_xref="InterPro:IPR016160"
/db_xref="InterPro:IPR016161"
/db_xref="InterPro:IPR016162"
/db_xref="InterPro:IPR016163"
/db_xref="InterPro:IPR029510"
/db_xref="PDB:1CW3"
/db_xref="PDB:1NZW"
/db_xref="PDB:1NZX"
/db_xref="PDB:1NZZ"
/db_xref="PDB:1O00"
/db_xref="PDB:1O01"
/db_xref="PDB:1O02"
/db_xref="PDB:1O04"
/db_xref="PDB:1O05"
/db_xref="PDB:1ZUM"
/db_xref="PDB:2ONM"
/db_xref="PDB:2ONN"
/db_xref="PDB:2ONO"
/db_xref="PDB:2ONP"
/db_xref="PDB:2VLE"
/db_xref="PDB:3INJ"
/db_xref="PDB:3INL"
/db_xref="PDB:3N80"
/db_xref="PDB:3N81"
/db_xref="PDB:3N82"
/db_xref="PDB:3N83"
/db_xref="PDB:3SZ9"
/db_xref="PDB:4FQF"
/db_xref="PDB:4FR8"
/db_xref="PDB:4KWF"
/db_xref="PDB:4KWG"
/db_xref="PDB:5L13"
/db_xref="UniProtKB/Swiss-Prot:P05091"
/protein_id="CAG33272.1"
/translation="MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNE
WHDAVSRKTFPTVNPFTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRG
RLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT
IPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTA
LYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGS
SNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDE
FVERSVARAKSRVVGNPFDSKTEQGPQLDETQFKKILGYINTGKQEGAKLLCGGGIAA
DRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFT
KDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTV
TVKVPQKNS"
BASE COUNT 330 a 431 c 479 g 314 t
ORIGIN
1 atgttgcgcg ctgccgcccg cttcgggccc cgcctgggcc gccgcctctt gtcagccgcc
61 gccacccagg ccgtgcctgc ccccaaccag cagcccgagg tcttctgcaa ccagattttc
121 ataaacaatg aatggcacga tgccgtcagc aggaaaacat tccccaccgt caatccgttc
181 actggagagg tcatctgtca ggtagctgaa ggggacaagg aagatgtgga caaggcagtg
241 aaggccgccc gggccgcctt ccagctgggc tcaccttggc gccgcatgga cgcatcacac
301 aggggccggc tgctgaaccg cctggccgat ctgatcgagc gggaccggac ctacctggcg
361 gccttggaga ccctggacaa tggcaagccc tatgtcatct cctacctggt ggatttggac
421 atggtcctca aatgtctccg gtattatgcc ggctgggctg ataagtacca cgggaaaacc
481 atccccattg acggagactt cttcagctac acacgccatg aacctgtggg ggtgtgcggg
541 cagatcattc cgtggaattt cccgctcctg atgcaagcat ggaagctggg cccagccttg
601 gcaactggaa acgtggttgt gatgaaggta gctgagcaga cacccctcac cgccctctat
661 gtggccaacc tgatcaagga ggctggcttt ccccctggtg tggtcaacat tgtgcctgga
721 tttggcccca cggctggggc cgccattgcc tcccatgagg atgtggacaa agtggcattc
781 acaggctcca ctgagattgg ccgcgtaatc caggttgctg ctgggagcag caacctcaag
841 agagtgacct tggagctggg ggggaaaagc cccaacatca tcatgtcaga tgccgatatg
901 gattgggccg tggaacaggc ccacttcgcc ctgttcttca accagggcca gtgctgctgt
961 gccggctccc ggaccttcgt gcaggaggac atctatgatg agtttgtgga gcggagcgtt
1021 gcccgggcca agtctcgggt ggtcgggaac ccctttgata gcaagaccga gcaggggccg
1081 cagttggatg aaactcagtt taagaagatc ctcggctaca tcaacacggg gaagcaagag
1141 ggggcgaagc tgctgtgtgg tgggggcatt gctgctgacc gtggttactt catccagccc
1201 actgtgtttg gagatgtgca ggatggcatg accatcgcca aggaggagat cttcgggcca
1261 gtgatgcaga tcctgaagtt caagaccata gaggaggttg ttgggagagc caacaattcc
1321 acgtacgggc tggccgcagc tgtcttcaca aaggatttgg acaaggccaa ttacctgtcc
1381 caggccctcc aggcgggcac tgtgtgggtc aactgctatg atgtgtttgg agcccagtca
1441 ccctttggtg gctacaagat gtcggggagt ggccgggagt tgggcgagta cgggctgcag
1501 gcatacactg aagtgaaaac tgtcacagtc aaagtgcctc agaagaactc ttaa
//