LOCUS BX641132 5240 bp mRNA linear HUM 16-OCT-2008
DEFINITION Homo sapiens mRNA; cDNA DKFZp686A22123 (from clone DKFZp686A22123).
ACCESSION BX641132
VERSION BX641132.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5240)
AUTHORS Lauber J., Bahr A., Mewes H.W., Weil B., Amid C., Osanger A.,
Fobo G., Han M., Wiemann S.
CONSRTM The German Human cDNA Consortium
JOURNAL Submitted (26-AUG-2003) to the INSDC. MIPS, Ingolstaedter
Landstr.1, D-85764 Neuherberg, GERMANY
COMMENT Clone from S. Wiemann, Molecular Genome Analysis, German Cancer
Research Center (DKFZ); Email s.wiemann@dkfz-heidelberg.de;
sequenced by Qiagen (Hilden/Germany) within the cDNA sequencing
consortium of the German Genome Project.
This clone (DKFZp686A22123) is available at the RZPD in Berlin.
Please contact the RZPD: Ressourcenzentrum, Heubnerweg 6,
14059 Berlin-Charlottenburg, GERMANY; Email: clone@rzpd.de
Further information about the clone and the sequencing project
is available at http://mips.gsf.de/proj/cDNA/
FEATURES Location/Qualifiers
source 1..5240
/db_xref="H-InvDB:HIT000055671"
/organism="Homo sapiens"
/map="1q43"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="686 (synonym: hlcc3). Vector pSport1_Sfi; host
DH10B; sites SfiIA + SfiIB"
/clone="DKFZp686A22123"
/tissue_type="human uterus"
/db_xref="taxon:9606"
CDS join(<1..759,759..2459)
/codon_start=1
/gene="DKFZp686A22123"
/product="hypothetical protein"
/note="5-methyltetrahydrofolate--homocysteine
methyltransferase, N-terminus truncated"
/note="The frame shift was determined manually"
/db_xref="GOA:Q6MZH4"
/db_xref="H-InvDB:HIT000055671.14"
/db_xref="InterPro:IPR000489"
/db_xref="InterPro:IPR003759"
/db_xref="InterPro:IPR004223"
/db_xref="InterPro:IPR006158"
/db_xref="InterPro:IPR011005"
/db_xref="InterPro:IPR011822"
/db_xref="InterPro:IPR033706"
/db_xref="InterPro:IPR036594"
/db_xref="InterPro:IPR036724"
/db_xref="InterPro:IPR037010"
/db_xref="UniProtKB/TrEMBL:Q6MZH4"
/protein_id="CAE46059.1"
/translation="GMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCC
QGKCIVNSISLKEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGME
EHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSG
MDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTD
EWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDL
FGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATV
KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLD
EMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQL
LDENLKDEYFEEIMEEYEDIRQGHYESLKERRYLPLSQARKSGFQMDWLPEPHPVKPT
FIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDD
AHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAE
KDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKA
LGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEK
LTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALR
KNISVAEVEKWLGPILGYDTD"
regulatory 5208..5213
/regulatory_class="polyA_signal_sequence"
polyA_site 5221
BASE COUNT 1578 a 1055 c 1229 g 1378 t
ORIGIN
1 ggcatgctag atggtccaag tgcaatgacc agattttgca acttaattgc ttccgagcca
61 gacatcgcaa aggtaccttt gtgcatcgac tcctccaatt ttgctgtgat tgaagctggg
121 ttaaagtgct gccaagggaa gtgcattgtc aatagcatta gtctgaaaga aggacaggca
181 acagaaacag acacaaaaat cagagtgtgc acccgggcct accatctgct tgtgaaaaaa
241 ctgggcttta atccaaatga cattattttt gaccctaata tcctaaccat tgggactgga
301 atggaggaac acaacttgta tgccattaat tttatccatg caacaaaagt cattaaagaa
361 acattacctg gagccagaat aagtggaggt ctttccaact tgtccttctc cttccgagga
421 atggaagcca ttcgagaagc aatgcatggg gttttccttt accatgcaat caagtctggc
481 atggacatgg ggatagtgaa tgctggaaac ctccctgtgt atgatgatat ccataaggaa
541 cttctgcagc tctgtgaaga tctcatctgg aataaagacc ctgaggccac tgagaagctc
601 ttacgttatg cccagactca aggcacagga gggaagaaag tcattcagac tgatgagtgg
661 agaaatggcc ctgtcgaaga acgccttgag tatgcccttg tgaagggcat tgaaaaacat
721 attattgagg atactgagga agccaggtta aaccaaaaaa atatccccga cctctcaata
781 taattgaagg acccctgatg aatggaatga aaattgttgg tgatcttttt ggagctggaa
841 aaatgtttct acctcaggtt ataaagtcag cccgggttat gaagaaggct gttggccacc
901 ttatcccttt catggaaaaa gaaagagaag aaaccagagt gcttaacggc acagtagaag
961 aagaggaccc ttaccagggc accatcgtgc tggccactgt taaaggcgac gtgcacgaca
1021 taggcaagaa catagttgga gtagtccttg gctgcaataa tttccgagtt attgatttag
1081 gagtcatgac tccatgtgat aagatactga aagctgctct tgaccacaaa gcagatataa
1141 ttggcctgtc aggactcatc actccttccc tggatgaaat gatttttgtt gccaaggaaa
1201 tggagagatt agctataagg attccattgt tgattggagg agcaaccact tcaaaaaccc
1261 acacagcagt taaaatagct ccgagataca gtgcacctgt aatccatgtc ctggacgcgt
1321 ccaagagtgt ggtggtgtgt tcccagctgt tagatgaaaa tctaaaggat gaatactttg
1381 aggaaatcat ggaagaatat gaagatatta gacagggcca ttatgagtct ctcaaggaga
1441 ggagatactt acccttaagt caagccagaa aaagtggttt ccaaatggat tggctgcctg
1501 aacctcaccc agtgaagccc acgtttattg ggacccaggt ctttgaagac tatgacctgc
1561 agaagctggt ggactacatt gactggaagc ctttctttga tgtctggcag ctccggggca
1621 agtacccgaa tcgaggcttt cccaagatat ttaacgacaa aacagtaggt ggagaggcca
1681 ggaaggtcta cgatgatgcc cacaatatgc tgaacacact gattagtcaa aagaaactcc
1741 gggcccgggg tgtggttggg ttctggccag cacagagtat ccaagacgac attcacctgt
1801 acgcagaggc tgctgtgccc caggctgcag agcccatagc caccttctat gggttaaggc
1861 aacaggctga gaaggactct gccagcacgg agccatacta ctgcctctca gacttcatcg
1921 ctcccttgca ttctggcatc cgtgactacc tgggcctgtt tgccgttgcc tgctttgggg
1981 tagaagagct gagcaaggcc tatgaggatg atggtgacga ctacagcagc atcatggtca
2041 aggcgctggg ggaccggctg gcagaggcct ttgcagaaga gctccatgaa agagttcgcc
2101 gagaactgtg ggcctactgt ggcagtgagc agctggacgt cgcagacctg cgcaggctgc
2161 ggtacaaggg catccgcccg gctcctggct accccagcca gcccgaccac accgagaagc
2221 tcaccatgtg gagacttgca gacatcgagc agtctacagg cattaggtta acagaatcat
2281 tagcaatggc acctgcttca gcagtctcag gcctctactt ctccaatttg aagtccaaat
2341 attttgctgt ggggaagatt tccaaggatc aggttgagga ttatgcattg aggaagaaca
2401 tatctgtggc tgaggttgag aaatggcttg gacccatttt gggatatgat acagactaac
2461 tttttttttt tttgcctttt ttattcttga tgatcctcaa ggaaatacaa cctagggtgc
2521 cttaaaaata acaacaacaa aaaaacctgt gtgcatctgg ctgacacttc cctgcttctg
2581 gttttcgaag actatttagt ggaaccttgt agaggagcag ggtcttcctg cagtgcctgg
2641 aaaacaggcg ctgttttttt tgggaccttg cgtgaagagc agtgagcagg gttcctgtgg
2701 tttccctggt ccctctgaga tggggacaga ctgaagacag aggtcgtttg atttcaaagc
2761 aagtcaacct gcttttttct gtttttacag tggaatctag gaggccactt agtcgtcttt
2821 ttttcctctt agaagaaaag cctgaaactg agttgaatag agaagtgtga ccctgtgaca
2881 aaatgatact gtgagaaatg gggcatttta atctaagtgg ttataacagt ggattctgac
2941 ggggaaggtg tagctctgtt ctcttcggaa gacctcgttt tctaaaggct ggactaaatg
3001 gctgcagaac tccctttggc aaaaggcatg cgctcactgc ttgcttgtca gaaacactga
3061 agccatttgc cccagtgtgg tcaagcagcc atgctttctg ggcattttcg tcctcccata
3121 atttcatatt tccgtacccc tgaggaaaca aaaaggaaat gaggagagaa agttactgtt
3181 aagggtggtt aacatttttt ttgttttgtt ttgttttggt tttttttttt ttgagacaga
3241 gtctggctct gtcgcccagg ctggagtgca ggggcgcaat ctcggctcat agcaagctcc
3301 gcctcctggg ttcatgccat tctcctgcct cagcctccag agtagctggg actacaggtg
3361 cccgccacca cacccggcta attttttgtg tttttacaaa atacaaaaaa gtagagacag
3421 gatttcactg tgttagccag gatggtcttg atctcccgac ctcgtgatct gcccacctca
3481 gcctcccaaa atgctgggat tacaggcgtg agccaccgag cctggccggt taacatcttt
3541 taattgtttc caggattgag caggttctca gctgggctct gatatcccgt gcggagttgg
3601 acaagtgggc agcataaagt cactcatttc ttaccatttt attcccctca attctcaata
3661 tattcagtaa tgaagaatgg tgccaccact caagcaacaa gcctcaaact cacccatgtc
3721 atctttttct tggatgattg cagttatttc aaaaatttgc atgcaaaata tacactcatc
3781 ctacttcaag atggtggtgg caatagtcag gagaaggtag cattggagtc ctggtttgat
3841 tcgaaggatg aagacgaaga agcaagggag gaacaaatga agaaccatct ttgttcatga
3901 ataggaatat tcaagattat aaaggtatca ggtctcctaa aattgatcta tggatttaat
3961 accattttca atggaaattc caacagattt tattgaatga aacaagcagg tgtttatatg
4021 gagtagcaaa ggacttaaaa ttaccaaatg cttctaaata tgaaggagag gttggggaca
4081 cgcaccctat gtgataccaa gttttattgt caagacagtg tcatggtgca gaggtaggca
4141 ttttgagcag gggaacaaaa taagggccta gaaactcacc cgtgcatatg ttgacctttg
4201 caaaatgacc tggtgacatg gcaagtcagt ggggacagga aggaccactc cctaagtaat
4261 cccagaacaa tggctattca tgtgggaaaa aaagaaattt tactttctct caccttacct
4321 ggtgattagt tccaaatatg ttaagggctt taatacaaaa agcaaaaatt gtcagtgttt
4381 ggatgaaaaa agccttaggg caggaaagaa tctcttgaga cataaagtag taatcataaa
4441 ggacaagatg gttaagtcaa ttctgttaaa actcaaggct tatattaagc aaacacttga
4501 agtgagaaga tgatccacaa cttgagaaga catttataat acaaataact gatgaaggat
4561 tcataatcac aaatatagag aattcctatt taaaaaaata gaaaaatagt gaagactaca
4621 caagaggaaa tagggctttt aaataaatag atgttctgta gcattggtca gggaaatatg
4681 aattaggacc acaatgagat tccattttat atccataaga tttgcaaagg ttgggtctga
4741 cagtaccagt tgttagatct gtagggactt gtacaacatt gtggatgtgt aaacaggcac
4801 cactgcttta aaaaacaatt atcccttaca gacttgaaca tttgcagacc ttatgatctt
4861 gcttccaact cccacctgta tgtccagcaa actcttgcat gtggccacta ggaggaatgt
4921 gtaagaatgt tcatagttac atatttataa tagttaataa ctggaaaaag tgaaatgtat
4981 gtctgtctac aggaaaatag gtgaataatt agatatatat attcattcta cgggatatta
5041 ttcagtagtg gaaatgagtg aactacagct atacctcaca ataagaatga atctcagaaa
5101 atattaagga aaaaagcaag tttgaagaga ccacatgggg cgtactattt ttattgagcc
5161 caaaaacaag caaaaccaaa gaatatgtag tctaagcata cgtatacaat aaaactatgc
5221 tattaaaaaa aaaaaaaaaa
//