LOCUS BX537946 7557 bp mRNA linear HUM 16-OCT-2008
DEFINITION Homo sapiens mRNA; cDNA DKFZp686C0686 (from clone DKFZp686C0686);
complete cds.
ACCESSION BX537946
VERSION BX537946.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7557)
AUTHORS Poustka A., Albert R., Moosmayer P., Schupp I., Wellenreuther R.,
Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M.,
Wiemann S.
JOURNAL Submitted (17-JUN-2003) to the INSDC. MIPS, Ingolstaedter
Landstr.1, D-85764 Neuherberg, GERMANY
COMMENT Clone from S. Wiemann, Molecular Genome Analysis, German Cancer
Research Center (DKFZ); Email s.wiemann@dkfz-heidelberg.de;
sequenced by DKFZ (German Cancer Research Center,
Heidelberg/Germany) within the cDNA sequencing consortium of
the German Genome Project.
This clone (DKFZp686C0686) is available at the RZPD in Berlin.
Please contact the RZPD: Ressourcenzentrum, Heubnerweg 6,
14059 Berlin-Charlottenburg, GERMANY; Email: clone@rzpd.de
Further information about the clone and the sequencing project
is available at http://mips.gsf.de/proj/cDNA/
FEATURES Location/Qualifiers
source 1..7557
/db_xref="H-InvDB:HIT000054730"
/organism="Homo sapiens"
/map="4q13.1"
/mol_type="mRNA"
/dev_stage="adult"
/clone_lib="686 (synonym: hlcc3). Vector pSport1_Sfi; host
DH10B; sites SfiIA + SfiIB"
/clone="DKFZp686C0686"
/tissue_type="human retina"
/db_xref="taxon:9606"
CDS 80..2989
/codon_start=1
/gene="DKFZp686C0686"
/product="hypothetical protein"
/note="receptor-type protein-tyrosine kinase,
differentially spliced"
/db_xref="GOA:P54756"
/db_xref="H-InvDB:HIT000054730.15"
/db_xref="HGNC:HGNC:3389"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR001090"
/db_xref="InterPro:IPR001245"
/db_xref="InterPro:IPR001426"
/db_xref="InterPro:IPR001660"
/db_xref="InterPro:IPR003961"
/db_xref="InterPro:IPR008266"
/db_xref="InterPro:IPR008979"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR011641"
/db_xref="InterPro:IPR013761"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR016257"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR020635"
/db_xref="InterPro:IPR027936"
/db_xref="InterPro:IPR034277"
/db_xref="InterPro:IPR036116"
/db_xref="PDB:2R2P"
/db_xref="PDB:4ET7"
/db_xref="UniProtKB/Swiss-Prot:P54756"
/protein_id="CAD97914.1"
/translation="MGDLGWIAFPKNGWEEIDEVDENYAPIHTYQVCKVMEQNQNNWL
LTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQY
IKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVY
YKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIG
KCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRR
ESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAG
VCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVN
VTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIK
SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASSDQSQIPVIA
VSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCVVAHPSLIWRCGYSKAKQDPEEEK
MHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSG
RLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVM
IVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILI
NSNLVCKVSDFELSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGI
VMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPK
FDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRY
TEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL"
regulatory 7516..7521
/regulatory_class="polyA_signal_sequence"
polyA_site 7539
BASE COUNT 2452 a 1280 c 1462 g 2363 t
ORIGIN
1 gagcgcgctg gacgctgctg ctgcagacta aatcgcagtc tcatctcaaa ttgtgaattt
61 attggattca cgcactgtca tgggggacct gggatggatt gcttttccaa aaaatgggtg
121 ggaagagatt gatgaagtgg atgaaaatta tgcccctatc cacacatacc aagtatgcaa
181 agtgatggaa cagaatcaga ataactggct tttgaccagt tggatctcca atgaaggtgc
241 ttccagaatc ttcatagaac tcaaatttac cctgcgggac tgcaacagcc ttcctggagg
301 actggggacc tgtaaggaaa cctttaatat gtattacttt gagtcagatg atcagaatgg
361 gagaaacatc aaggaaaacc aatacatcaa aattgatacc attgctgccg atgaaagctt
421 tacagaactt gatcttggtg accgtgttat gaaactgaat acagaggtca gagatgtagg
481 acctctaagc aaaaagggat tttatcttgc ttttcaagat gttggtgctt gcattgctct
541 ggtttctgtg cgtgtatact ataaaaaatg cccttctgtg gtacgacact tggctgtctt
601 ccctgacacc atcactggag ctgattcttc ccaattgctc gaagtgtcag gctcctgtgt
661 caaccattct gtgaccgatg aacctcccaa aatgcactgc agcgccgaag gggagtggct
721 ggtgcccatc gggaaatgca tgtgcaaggc aggatatgaa gagaaaaatg gcacctgtca
781 agtgtgcaga cctgggttct tcaaagcctc acctcacatc cagagctgcg gcaaatgtcc
841 acctcacagt tatacccatg aggaagcttc aacctcttgt gtctgtgaaa aggattattt
901 caggagagag tctgatccac ccacaatggc atgcacaaga cccccctctg ctcctcggaa
961 tgccatctca aatgttaatg aaactagtgt ctttctggaa tggattccgc cagctgacac
1021 tggtggaagg aaagacgtgt catattatat tgcatgcaag aagtgcaact cccatgcagg
1081 tgtgtgtgag gagtgtggcg gtcatgtcag gtaccttccc cggcaaagcg gcctgaaaaa
1141 cacctctgtc atgatggtgg atctactcgc tcacacaaac tatacctttg agattgaggc
1201 agtgaatgga gtgtccgact tgagcccagg agcccggcag tatgtgtctg taaatgtaac
1261 cacaaatcaa gcagctccat ctccagtcac caatgtgaaa aaagggaaaa ttgcaaaaaa
1321 cagcatctct ttgtcttggc aagaaccaga tcgtcccaat ggaatcatcc tagagtatga
1381 aatcaagtat tttgaaaagg accaagagac cagctacacg attatcaaat ctaaagagac
1441 aactattact gcagagggct tgaaaccagc ttcagtttat gtcttccaaa ttcgagcacg
1501 tacagcagca ggctatggtg tcttcagtcg aagatttgag tttgaaacca ccccagtgtc
1561 agttgcagca tccagcgatc aaagccagat tcctgtaatt gctgtgtctg tgacagtggg
1621 agtcattttg ttggcagtgg ttatcggcgt cctcctcagt ggaagttgct gcgaatgtgg
1681 ctgtgggagg gcttcttccc tgtgcgttgt tgcccatcca agcctaatat ggcggtgtgg
1741 ctacagcaaa gcaaaacaag atccagaaga ggaaaagatg cattttcata atgggcacat
1801 taaactgcca ggagtaagaa cttacattga tccacatacc tatgaggatc ccaatcaagc
1861 tgtccacgaa tttgctaagg agatagaagc atcatgtatc accattgaga gagttattgg
1921 agcaggtgaa tttggtgaag tttgtagtgg acgtttgaaa ctaccaggaa aaagagaatt
1981 acctgtggct atcaaaaccc ttaaagtagg ctatactgaa aagcaacgca gagatttcct
2041 aggtgaagca agtatcatgg gacagtttga tcatcctaac atcatccatt tagaaggtgt
2101 ggtgaccaaa agtaaaccag tgatgatcgt gacagagtat atggagaatg gctctttaga
2161 tacatttttg aagaaaaacg atgggcagtt cactgtgatt cagcttgttg gcatgctgag
2221 aggtatctct gcaggaatga agtacctttc tgacatgggc tatgtgcata gagatcttgc
2281 tgccagaaac atcttaatca acagtaacct tgtgtgcaaa gtgtctgact ttgaactttc
2341 ccgggtactg gaagatgatc ccgaggcagc ctacaccaca aggggaggaa aaattccaat
2401 cagatggact gccccagaag caatagcttt ccgaaagttt acttctgcca gtgatgtctg
2461 gagttatgga atagtaatgt gggaagttgt gtcttatgga gagagaccct actgggagat
2521 gaccaatcaa gatgtgatta aagcggtaga ggaaggctat cgtctgccaa gccccatgga
2581 ttgtcctgct gctctctatc agttaatgct ggattgctgg cagaaagagc gaaatagcag
2641 gcccaagttt gatgaaatag tcaacatgtt ggacaagctg atacgtaacc caagtagtct
2701 gaagacgctg gttaatgcat cctgcagagt atctaattta ttggcagaac atagcccact
2761 aggatctggg gcctacagat cagtaggtga atggctagag gcaatcaaga tgggccggta
2821 tacagagatt ttcatggaaa atggatacag ttcaatggac gctgtggctc aggtgacctt
2881 ggaggatttg agacggcttg gagtgactct tgtcggtcac cagaagaaga tcatgaacag
2941 ccttcaagaa atgaaggtgc agctggtaaa cggaatggtg ccattgtaac ttcatgtaaa
3001 tgtcgcttct tcaagtgaat gattctgcac tttgtaaaca gcactgagat ttattttaac
3061 aaaaaaaggg ggaaaaggga aaacagtgat ttctaaacct tagaaaacat ttgcctcagc
3121 cacagaattt gtaatcatgg ttttactgaa gtatccagtt cttagtcctt agtcttcatt
3181 tttcatgaag caaacatatc ttgcattaaa agggacatga agttagacat catcttaagt
3241 tacaacaaca gaatccttcc cactacttct acaaaatttt gtacatgaaa tatataatta
3301 tatagcactt ttatagactg aattaaggca acccctttca aaacttccag ggatctactt
3361 gaaaggaaat gttttatagc catttgtgag ctaacaaaag ctacagttta ctgaagttta
3421 cttcaagtct taattgtcta caaaagtgta ttgaagagca atatgattag attatttctt
3481 aatagatatc ttcttttgta attttaaaat gctgttacac agcgttaagt tatagaaact
3541 agtgtgtaaa catgttgctt catcaagaaa aagtacaata cagggtgtat atttattttt
3601 tgtgttataa agtttacttt tagttgctct tctagagatt attaggtaat aaatgtgtat
3661 atactgtata atttgcaata tacccaggaa ctgatttaag atggaattgt gtgtgtgttt
3721 gcttgcacat gtgtgtgtta ccattctgct tgcatttcta atagtgtttc aattttagca
3781 acatatagga gcaagtgttc cagaatgtaa tatgaatagg agaaataggg aagcagtaaa
3841 acaaaattta acacaagctt gtgtctcttt tcctctcatg tgtccaaaag ctaatctctt
3901 tattcactaa aaggaaatgt gtataagact aaatcccctt tggcttttta aaaacatttt
3961 gtgatatcag tgacaatgca gttcttctag ccattaatct tgtacccctg taagaaattt
4021 cacctttctg agtcctgaaa agtatcttgt caagcaaagt tgacaccgaa gggcacattt
4081 tcagcaggat gtagaaggat ttaactgtgc aggcttctgt taatgttgtt aaatccaggc
4141 acatagcacg aagcatcacc cttaagtgtt aatccgttgt aaccattccc attttgactc
4201 agttctagaa attttgactc taaggcagca atggaattat gacaaatata tatatataca
4261 catacacaca cacaaatata tatatatgct tatttccctt cagaatttta tttcaataat
4321 tgataagttt tatttttaat ggatgtttat tcatttgtta atttcagttt gtattcagtt
4381 acatggcttt gagtttattt tattgaacca atccaaggta ttatgtaatt aggcttatta
4441 aggaatataa catatcttct atgtatgctc tatataccac acatgatgaa gacttatatt
4501 tgtgatacaa attatgcagt gtattggaaa ttgtccaaaa ctgagctcct gagataacca
4561 acatttttgt attattacac tttataaaaa ttatggaatg tcgtgtgatt agtcaaaatc
4621 agagcattta aataaaatac agcctactca tgattatcaa tgttaatagt acagtagatc
4681 agagaagcct ggattaatga aatttatcag aaatatagcc acgttatatt aatggtattc
4741 ttttttccaa gcacttgttt tatttgaata ttagcacata taagaataaa cttttgggaa
4801 ataactactt cctattctgc ccacccttta cttaagcagt aaagtacctc ttttctaaag
4861 aaccaggaaa catcaaaata accacaacaa aaatctaaac agttttcaaa taatacattc
4921 agttctcata ataataaggg ctatatacca tgggtccaca caaactgtgc tgcaaacata
4981 taatctatta gtttagtaaa atttccagag atgtgaattt aatattttct tgataaaatc
5041 ataaaaaagc atcaccatta ttaaagacgc atttgttcat ttcaataaac agaaattaat
5101 gaaacaaatt acttttgtac aaaataaatg atgattatgt ggcactttat tgaattttat
5161 agaaatattc caatctaagt gataaagtaa caattgagaa acttcagaat gaaagcctta
5221 ttgattcaaa aggaaaatta ccatatgctt tagggctgat gaacttgcca caattgctta
5281 gacataacaa agatattttc tacattgttt tccaacttta tatgctgaaa gataattagg
5341 aggtccgggt ggagtgtatc taaatgacta gaactttaag ttgcaatata gattttctct
5401 ttttaacaaa ggaagaatat aaattaattt ggatcaaatt tatttgcctt ctttgcaatc
5461 ttggtgatca ttttggaaag taaattgaaa ggaaagttaa atagccacat agttttcttt
5521 tgcatctcaa tttggttgag aatttctaag gaaggttaat atgactttag aatgaataaa
5581 gagactgtca aacaacaagt actctcccta aaaaagagga aagaatgcct tcctaaaata
5641 tttgtttcct attgtatatg tcaccaattg gaaaatgcca atctcatctg caagtgtgag
5701 aaatggaaca aggagaggag ccaactctag taaaatgtag tgaggccata atccaaggca
5761 aagtttaaca aatcttgatt gtgtaatttc ttattctgtt gattcatttt gtcacccacc
5821 agactaccaa aaataaagca cagacatgac aattttagta tatacaacag atttggcaaa
5881 taatacataa tcttattgta attgccagta gcaatatctt aaggggcatg agtctttcac
5941 agtattggac tttgaaaaat tggtacaggg agcaattttc aacagactga tacttgaagt
6001 cactcaatta ctactttgac ctatcataat ttgtttctaa tcttgtcatt tgctcatata
6061 tactattaat ataaccagtt gctcttttca taatgtacta tttctatgta aagatgtaaa
6121 gattttgatt ttcctatgtt ttaaaattgt aatgtgcatg atcttttatt tcttgtgttt
6181 caattaccaa gtcagtattc taaggttgta agattactgt aaaaattata ttccaatatt
6241 ttatctaaac ttaagtgtgg ccagcattat tggtttcaga gttgcctaaa caacacagaa
6301 tatccttaat tcagtttgta aaagagtttt gaccagtgta aaaaagtgaa gacacagttt
6361 catgtttcaa gtttaaaatg gaaagttaat atcatttgag cacttatgtg ttttcatgtc
6421 ttctacttaa tctgtatgtg aaagtaaaat atttttaaca ccattattta tgccatgtaa
6481 agtgggttct cagaagcaca agcacagata tttaccttct gaagacattt ttggctataa
6541 aagtgcattg gatggcaaac actatttgag tcaggtgtta gaaatttatt agatgtatta
6601 tattacatag tagaataagg tccctttctc attttgtttt tcctaaaaat aagaaaaaaa
6661 agaagtgtga tagtaaactg tctttgctaa tgtcctgcca ggtgtttaac ttcaaattaa
6721 gcaaaaagta ggtacaatat gatgatgatc ctgatgatga tgatgatgat gatgatgaag
6781 aataaatgga atcaaaatgc tagttttatt tgacattaat aagtaaaata agtcatcatt
6841 ttttcaactc tgtagcacag ctgtttacat tgaataattt tctctattgt gctgttaatt
6901 atatagtaat gtatcaaaat agaaatagga actttctttt catttcttat tcatttatga
6961 agaaatcttt tcacacataa atgattgaat gttcttgttc agaatgacca cataatcatt
7021 gcttagaaga agataccaat tcttttaaaa gaaaaaaagt ctgtttataa taatcagaat
7081 caaatgttgt ttgtttcttc taaacgttaa tggagaaaat tgaaggtggt aaaatgtcat
7141 gtttattcag gctgggaact gtattcacag tagaagtttc agtggtcaac atatctatga
7201 ctctttaggc tgctgtagtt ttacagtcaa ttatttaaaa gtgagtagtt acatttataa
7261 gagcctgaga atacttagac tcagtcattt gttagtattt ttaccaaaat ctcttagttt
7321 cagacatgtc agaagcagct atatagcata tcttattcta tgatatacat caggctatct
7381 caagttcctg tctcacagtt aattcaaaga aggattagga tttctgtatt ttttctcatt
7441 tgaatcttta tgtgcatttg gtttgtgtac atgctttttg tagtgtaaga tatgaaattt
7501 tatatttttt cagaaaataa aaaccctttg aatacagtta aaaaaaaaaa aaaaaaa
//