LOCUS BK000977 8806 bp DNA linear HUM 03-FEB-2006
DEFINITION TPA_exp: Homo sapiens keratin 5c (KRT5C) gene, complete cds.
ACCESSION BK000977
VERSION BK000977.1
KEYWORDS Third Party Data; TPA; TPA:experimental.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8806)
AUTHORS Hesse,M., Magin,T.M. and Weber,K.
TITLE Genes for intermediate filament proteins and the draft sequence of
the human genome: novel keratin genes and a surprisingly high
number of pseudogenes related to keratin genes 8 and 18
JOURNAL J. Cell. Sci. 114 (PT 14), 2569-2575 (2001)
PUBMED 11683385
REFERENCE 2 (bases 1 to 8806)
AUTHORS Hesse,M., Weber,K. and Magin,T.M.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-2003) Physiological Chemistry, University of
Bonn, Nussallee 11, Bonn 53115, Germany
COMMENT THIRD PARTY DATABASE: This TPA record uses data from
DDBJ/EMBL/GenBank entry AC055715.13.
FEATURES Location/Qualifiers
source 1..8806
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q13.13"
gene 1001..7809
/gene="KRT5C"
CDS join(1001..1471,2111..2325,2774..2834,3324..3419,
3945..4109,4752..4919,6389..6609,7085..7119,7610..7809)
/gene="KRT5C"
/note="type II keratin"
/codon_start=1
/product="keratin 5c"
/protein_id="DAA00404.1"
/translation="MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAG
FGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPA
CLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRF
LEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRS
MRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLK
CLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQ
TKCPCLITNFLSLGNQIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQ
RASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALD
MEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAGSSGS
TQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR"
BASE COUNT 2070 a 2199 c 2447 g 2090 t
ORIGIN
1 tacttcctgt ttgaaaattg agtgctccct gaagttgcca ggaaactggc agaacagccc
61 accctgaacc tgggagtgaa actcaggggg tcctgttcct tggtgacttc agccataggg
121 tgtttcccca gggagtgcag gggctaatat cccagctcct gcctgacttc ctagagtagg
181 acaaataatc ttatccagga gagaaaatcc aactggagga aatgcagctg actggaaagg
241 ttctcatggt tgtaaggcaa tgtcaaggtc accaccaccc aggccctgcc caacacagaa
301 ggccctagac aatatccctg ctaggggggc atgcagatgc tgcagagtca ttcctcttcc
361 ttcctggggt ccacttcact gctagacagc tgtggtcctt agcatggccc aaggacggac
421 cctggagctt cttacccaga tccagatctt tgaggacatc tttccaagaa gaatcatctt
481 tccatgtctt cttttccctg aggtaaaaat tccagcttcc acacaagacc ctataataga
541 gagatggttt cttttgggaa gaaacctggg gtttttcagg tgagtctact ctggggaaag
601 ccaggcattt cccctgctcc ttgctgatgg ttaagcaaga aggaggtagc actggaaaaa
661 taaagctagg agatctcttc aggggataac tcttcaggtc cttaattagg gagcacagat
721 aaactccaaa ttagaccact ccactctgca agggcagcat attccacttg ctatcagaag
781 agctttgttg ctgcaaaggg cttggagatc tctgttctac aaattgccca tggcccctgg
841 cccatcagca ggggaaagga gatagtggag agacgccctt ttccggtgtc ctgggctcaa
901 cagggataaa aggaggcagc actctgggtg ccccatcagt gtgttctcta ccccttggag
961 actgcttttc tccagctctg tcaactcaac ctttcccacc atgagtcggc aactgaacat
1021 caagtccagt ggtgacaagg gcaacttcag tgtgcattcg gcagtggtgc caaggaaggc
1081 tgtgggtagc ctggcttctt actgtgcagc tggcagaggg gctggcgctg gctttggcag
1141 tcggagcctc tatagccttg gagggaatcg gcgtatttct ttcaatgtgg ctggtggcgg
1201 cgttcgggct ggaggttacg gcttcaggcc tggctctggg tatggagggg gccgggccag
1261 tggctttgct ggcagtatgt ttggcagtgt ggccctgggg cctgcatgtt tgtctgtgtg
1321 cccacctggg ggcatccacc aggtcactgt caacaagagc ctcttggccc ccctcaacgt
1381 ggagctggac cctgagatcc agaaggtgcg cgcccaggag cgggaacaga tcaaggtgct
1441 gaacgacaag ttcgcctcct tcattgacaa ggtgggtctc ataggaggag gatgaggccg
1501 caccctgagg cctgagcagt tttcctgctg cctgggaatg gactgcacac tgtggctgga
1561 aaggtgcagc tgggcctcag gaagggcttc ctcaccatta gggaaggaga gtaggtctgt
1621 gagccacgga ggacaaagga atacatgaat atatcggctt ctttggcgat tttgcaggga
1681 aggatgggaa gctgggtaaa gagcagccct tccttgacaa aaaagtgatg agtttcttga
1741 ggacagctgg atcttccaag aacatgaaag gctaatagaa tccagcagtg ttcagaggga
1801 agggctcatg gtacaggaag agacacttag ttgagacata aggaaggaca tctcctggga
1861 ccagggccga gcaatagaag aaagctgtgg aaactccttg agtgagttct cagtgatgcc
1921 ttgtccagaa ggctaggaaa tgagcacttg taaaggatct agtttgtgtg gaatggcaag
1981 ggtggagagt caagacatga gcaaaaatga ctacaacaat ctatggcaaa cctggggagt
2041 caatggtgtg tgtccagggg gcatgactgc acccattgtg gttccaggtg tctgttgatt
2101 tgggttccag gtacgcttcc tagagcagca gaaccaggtt ctagaaacca agtgggagct
2161 gctgcagcag ctggacctga acaactgcaa gaagaacctg gagcccatcc ttgagggcta
2221 catcagcaac ctgcggaagc agctggagac actgtctggg gacagggtga ggctggactc
2281 ggagctgaga agcatgaggg atctggtgga ggactataag aagaggtgag caggctccac
2341 ccgagggtca cagaccatgt ttcccgtgcc tctgggctca cctgatctct gtgccattat
2401 tttttaggag atgggggagt atgcaccagg gtcaggagct cacatccctt tctctggcta
2461 gggggaaggg cctatcctct ttgatgataa cttcctgcct agttgatagg aagcggttcc
2521 tgtgctcctt gacccactga aatgttcagt tgctggtgtc gggagcccaa taggcacctg
2581 ggtgttttcc taacatgcaa aaactaggag acaagtgaag caactcaggg atatcttact
2641 cctgtcacta gcctcttact gctcacccca gagaccctgc agggaccctg tatcccaaac
2701 atttgcctgg ccagcaggaa gagaaagttc cttggctaag ggggctaagg ccatctactc
2761 tccctgctgg cagatatgaa gtggagatta accggcgcac gacagcagag aatgagtttg
2821 tggtgcttaa gaaggtaaga gagggaggag cctccttatt agggtctctc gcacccccat
2881 cttaacaact ctgctcagga cttcagccca ggaggctggg gagggggctg gtgcctggtg
2941 agggggctgg tgcctggtga gggtggagtc atagtcctgg cctccagtga gttggagagg
3001 aaagacacac actcaggaaa tggacagaga cagacagaat tctggtctgg gaactgtgaa
3061 actcgggtcc agctcaacct tgctgtgtga cctgaggaaa cctactacct ctctgggctt
3121 tgttttctcc aggcataaca gagctgcccc atcctccttt ccctattccc aaagcttcag
3181 gcagcctgag aagaaattga tattgagtga gctttccttt gtgggtagaa aatagaaaat
3241 caggtggctt tgaggcagga gttgggcagg gcagctgtgg gatgagggtt gcatccccca
3301 atgactctgg ggcctcttgg caggatgcag atgcagccta cgcagtcaag gtggagcttc
3361 aggccaaagt ggactcactg gacaaagaaa tcaagttcct caagtgtctg tatgatgcag
3421 taaggacact cctgtccccc caccctcacc ctgcctcctt cccgactctt ccagggagat
3481 accaaaagga gagatttagg atcaacaaaa tgaaagatgt tttggtagaa aggtacaaaa
3541 ccctgcacca ggagaccatg gaagtgcagg atgctggtcc ttggaggcca tacatacagg
3601 aggaaattga tcttgataca atagtggact tgcccacggg caggaaaaga taacccagtg
3661 aggtcttaca aagcacagag ccttggattc tgtgaaattg tggaaaatgc attattcacc
3721 cgtctgcatg tgccagcggg catctgccat atgcaggggt tcctgctgct gttagctgct
3781 ctccctcagc tctgcagaca catcccagag ggcacttctt ccccctactt tgtccccgtg
3841 gatcctagca gcctattggg ccagggacca tgggcccaga agactgatgg ggcagaagag
3901 ggaagccagg gggttgctga atctgtcttc ctctctcaat gcaggagatc gctcagatcc
3961 agactcacgc cagtgagacc tctgtcatcc tgtccatgga caacaaccgg gacctggacc
4021 ttgacagcat catcgctgag gtccgcatgc attatgagga gatcgccctg aagagcaagg
4081 ccgaggccga ggccctgtac cagaccaagg tggtcaccga atgggtctcc tcccacagca
4141 gcccttcgct tcctgggagg ggtcacctgc acagtgaatg tgaggaatac ttttgtgggc
4201 atgctgaatg aaagaaaggt tccaaccaag gcttcaagga aaaaaggaat tcttagcaga
4261 gcttgttatc aaagataaat catgaaactg gtatggattg aatatatgca acagagagga
4321 tccctcactt ctttcctcca tccacgaact gcctgttcct ctctgttgca ggtgaaagaa
4381 gtgaggtggt aaaacaaaca cacttatagg aatgggggca tgttgccaca gggcagaggg
4441 agaatcacag acttgcggga gtgtagccat gggtgaattt ggtggggggc gagtgagaga
4501 aggagaagcc tgtagctctt tcctgatccc cacgggaaga ctttcaaaag gaaatggaag
4561 gcgaggagtg ctctgagtaa tggaactatg ctttgggtaa actgagtaat ggaactatgt
4621 ttggggctgt cagggagaaa accccttacc tgggccccca ggaccctgtc ccagcactcc
4681 tcttcagttc cgttaaatcc caccgacagc cagggtggca ggggtggctt atttacagga
4741 cccttcccca gtgcccttgt ctcatcacca acttcctatc tctgggaaac cagatccagg
4801 agctgcagct ggcagccagt cggcatggtg acgacctgaa acacaccagg agcgagatgg
4861 tggagctgaa ccggctcatc cagaggatcc ggtgtgagat cgggaatgtg aagaagcagg
4921 tgggcagcag ccccacaaag aactcccggt ctccacagca ggctctggga tgaggaaatg
4981 gggcctgccc tttgggaaca agcaaatatc ccctgctggg cttaggggtc cctcggccac
5041 ccacagtctc cctttcccac cctgcctcgg taccctacca tcagagctgg taccccgccc
5101 agaactggga ggagcctcaa acctatttct ctgactcctc attttgcaga taaagcaact
5161 gggctgggaa ggggaaggga ctttcccaga gcccccagct ggtaatgaat ggagctagga
5221 ttagaaccca ggttcccctt ctgcagattt tttctgtgtc caatgaacct gccccatgtc
5281 ccctttgggt gccccctctg agggcagacc ctctgtctcc tcctcccact ggacatggaa
5341 catgtgtggg gtgcagaggg tatgcatcag gcgcctctgt tggccacacc aggttcctgc
5401 tctcggagtg gggcatggtc tgttgactga gggacacagc tgtcgatgaa gccctcctgg
5461 gttcccttgc cctgtgccat ggtactactt ccatgttagt gggcgggggg gtgggggtgg
5521 ggggcctgtc ttacctgaca gcagcaaatt ttaaacactg cgtcagtggg gagatgatat
5581 tggaggctgg aggatccttc ctgtgacctc tctgagaacc aggtctgctc tgctagtgat
5641 agaattgacc agcggaaaga tctgagcctg ttctccttct ggtgccccca caaccctcca
5701 tgctctgcag gcaaacacag ggacaactct acgactctac atttggccga ttcacaaatt
5761 ccatgagcat agttcctccc tctctgttag caacaggcat cgcaatgccc cccagatgtt
5821 catcagagtc cagcttctga ggttgtgcct ataatttagg gccttatcct cctgctctaa
5881 gggaaggcca gatgtgggag ccttcacaca gactctcccc agagtgctgg agtccagaaa
5941 cactcatctg gatgctaaca gatcagaagg atccccaatg gggagaggtc ctgcagcagg
6001 aatctgatca cagtgggacc gtggcatact gtctcatcct cagggctggc cttgctaggg
6061 gatcgggcat gattttcctg aacctgtagt attttgaatc tgtagatact ggtggcctcc
6121 ggtctcaggc actatctaac tttgcaaaca tcgacatttc ttcctgacct cctgaaatgc
6181 aactgcttcc acagcttcat gtgataacag ctttgaatac tcctctgcaa tagaaaatag
6241 aagagacaaa gttctggtgt tggctttgca gcttttactc cttgtcacct agggccccat
6301 ctgcaaaatg agggcattgt tctacttaac tggtatgagc taaatgtaat tttctgttct
6361 gatggtctct ctgttctttg cccttcagcg tgccagcctg gagacggcca tcgctgacgc
6421 tgagcagcgg ggagacaatg ccctgaagga tgcccaggcc aagctggatg agctggaggg
6481 cgccctgcac caggccaagg aggagctggc gcggatgctg cgcgagtacc aggagctcat
6541 gagcctgaaa ctggccctgg acatggagat tgccacctac cgcaagctgc tggagggcga
6601 ggagtgcagg taggtggggt ggaggggaaa gtgtgagaag ggactggggt gtggctcctg
6661 tctggctgag gggccacctg gagaacaaca tggttagtgc caatacaagc aagagatgtg
6721 gtgatttcgt gaactcagag gcagcttcct gcaaggggtt gttggacatg agccatgaag
6781 cgtagatggc cgtgtgctgc tgtgatgaga accgggggct cagacagacc tggggctaat
6841 gactggctct tcagcagggg ctaattattg gctttatcct atgctagtgg tgtggtctcg
6901 gtaaatcatc tagtatctcc aggactcttg ttttctcatc tgtaagatga aggcgatagt
6961 gtcagtttcg taagttgtta taaggatgag tttaaatgat gcacgtataa aagcaggagc
7021 ccattgatgt ttagtggaat ctcgacactg agtttttatc tttctctaac tttctgtctc
7081 acaggatgtc tggtgagaat ccatcctctg tgagcatctg tgagtattct tgagagatgc
7141 cttgggttgg gaaagccagg gaccctggga caaagtgatg tcacctccat ttactgtctc
7201 acctcccaag aagcttctgt tactgtcttg ggaaggtttc tgggcttcaa aggaaatgtt
7261 ctcccttttc atcctgtgaa atggtgactg aggtcatgcc cacccttttc ccttcctgtt
7321 tctcccctgg gacgttgtca tttggagaaa gggttggtgg acatggattt tcctagcatt
7381 tccaggaggg cagggactgt atctatctga tggggtcttc acctcacacg aagtccggcc
7441 cgtaataggc tctcagttca tctctgtagt gcttcttgac tactgagggt ggttctgcgg
7501 attaaatgag gtgttgttgt ggagaagccc ttggggacag ccgttaccat agctgttatc
7561 tgctgattga cactgctcct ctcccctgct cttggcccct cctcctcagc tgtcatcagc
7621 agtagcagct acagctacca ccaccccagc tctgcgggtg ttgaccttgg ggccagcgct
7681 gtggcaggca gctctggcag cacccagagc gggcagacca agaccacaga ggcgcgaggg
7741 ggagacctca aggacaccca gggcaagagc accccagcca gcatcccagc aaggaaagcc
7801 acccgctaga cccatggcct cacccacctc agcacttgga agaagaggtg actttgccac
7861 ccccaaaggt gtctgccaca cccaagttcc caggccctga gttttaaaac tgtctgtagt
7921 acactcaact gtctgcatcg tggtttagct tttactttca agctctgatt gacacagtca
7981 ccttccctgt ttccttaggt cccatgtgga ctaacgactt ctcattttcc tcgctgcctt
8041 tggctggcag gaggctttgg aggcacaagc cattataacc ttcttggccc taaggaagct
8101 gtgatcatcc ctagaaagag ggaaggagca ggagacgaca ggggaggggc tggtttgttc
8161 tgtgcttagg ccaagttagc tactgtctga gaggttttac atcccctgcc agcatggtgg
8221 ggtgacacga gacctgtaag caggtggtga gaagttagac agcctttact tgctccatca
8281 gaaacaactt tgcaggatga cgccaatatt taggacacca cgtgtacatc tgtagaccac
8341 cagctgcacc catctccaca aagccaagtg aaggtgtatt ggggattctc tgccagcctg
8401 tgtcacccac ccacctcctt cattatcagc aatagctacc atcatttgtc aagcacctac
8461 tagatgccag acaccctaca catattgcct cctgttctca tccattcctg caaagaagat
8521 gcaatgagca tccttggaac agactgggag cctgatccca agaggctgct gaactggccc
8581 cagtcaccca cctatgtgcc agagtcaggc ctggccgaca caaggatcta tgctttttct
8641 gtggtgtgtc actgcctttt taacaaaagg gctgtcaaag tcaccattct ttttgatgag
8701 ggcagcgtaa ttacattgcc ttttgtcagg actgtgggta tgtgatttgt cttccacagt
8761 ctctctgggg ctgtgtccta catagcttct gactctcaat ttttgg
//