LOCUS BC167157 4141 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH
domain 1, mRNA (cDNA clone MGC:176692 IMAGE:8862571), complete cds.
ACCESSION BC167157
VERSION BC167157.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4141)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4141)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAY-2008) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 15 Row: f Column: 5.
FEATURES Location/Qualifiers
source 1..4141
/db_xref="H-InvDB:HIT000436135"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176692 IMAGE:8862571"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+"
gene 1..4141
/gene="AGAP1"
/gene_synonym="GGAP1"
/db_xref="GeneID:116987"
/db_xref="HGNC:HGNC:16922"
/db_xref="MIM:608651"
CDS 584..2998
/gene="AGAP1"
/gene_synonym="GGAP1"
/codon_start=1
/product="ArfGAP with GTPase domain, ankyrin repeat and PH
domain 1"
/protein_id="AAI67157.1"
/db_xref="GeneID:116987"
/db_xref="HGNC:HGNC:16922"
/db_xref="MIM:608651"
/translation="MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQN
QIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESP
EGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYS
RMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNV
ERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLS
DYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLE
SRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVH
GKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVC
SSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSL
TGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMR
GNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVM
SSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQH
LLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGV
DVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSG
RVPTII"
BASE COUNT 955 a 1244 c 1193 g 749 t
ORIGIN
1 cccacgcgtc cgcaaggcgc ctgcgactcg gtcccaggtc ggcgggcggc gcgcggcggg
61 ctcgcgcggg ggccccggcg cgccgggcgg cgcagtacgc agcgcgcgga cccacgccac
121 ggccaggagc ccagagcagc gcggccacac tgcccagggg tcggccctcg gccccggcgc
181 tcggagcgcg gcggctgcct gggctttaat ggctgctccg cggagcagcg cctagggctg
241 gaaggcggct gcggctcagg aagtcacccg agcaagcctc cttcggggcc ggccgcaccc
301 gccgcggcgc gctccatggg ggcgcgctcc ccccgggcgg cccgctgacc cgggacgccg
361 gggcccgctc gctcgccggc cgcgcgtccc ggccatgaac tgagcccgcg ggccagcccc
421 gcgcctgctc cgcccgcgcc tttcttctcg cgcctcctcc gcccgccgcc ggcgggcccg
481 gctccccggg ggctgcggcg ccccgggctc ggcggcccgc gggccccggg gcgcggggcg
541 gcggcggcgg ggggcgcgcg gctccgggcg cggcgcctgc accatgaact accagcagca
601 gctggccaac tcggctgcca tccgggccga gatccagcgc ttcgagtcgg tccaccccaa
661 catctactcc atctacgagc tgctggagcg cgtggaggag ccggtgctgc agaaccagat
721 ccgggagcac gtcatcgcca tcgaagatgc cttcgtgaac agccaggaat ggacgctgag
781 tcgatctgtc ccggagctca aagtgggaat tgtgggtaac ttggccagcg gcaagtctgc
841 cctggtgcac cggtacctga cgggcacata tgtccaggag gagtctccgg aaggtggcag
901 gttcaagaaa gagattgtcg ttgatggaca gagctatctg ctgctgatca gagatgaagg
961 gggccccccg gaggcgcagt ttgccatgtg ggtggacgct gttatatttg tcttcagctt
1021 ggaggatgaa ataagtttcc agaccgttta ccactactac agtcgaatgg ccaactatcg
1081 gaacacgagc gagattcctc tggttctggt gggaacccag gatgccataa gttctgctaa
1141 cccgagggtc atcgatgacg ccagggcgag gaagctctcc aacgacctga aacggtgcac
1201 gtactacgag acgtgtgcta catacgggct gaatgtggag agggtcttcc aggacgttgc
1261 ccagaagatt gttgccacaa ggaagaagca gcagctgtcc ataggaccct gcaagtcgct
1321 acctaattct cccagccatt cctccgtctg ttccgcgcag gtgtctgccg tgcacatcag
1381 ccagacaagt aatggaggtg ggagtttaag cgactattcc tcctccgttc catcgactcc
1441 cagcatcagc cagaaggaac ttcggatcga tgttcctccc actgccaaca cgcccacgcc
1501 cgttcgcaag cagtctaagc gccggtccaa cctgttcacc tctcggaaag ggagcgaccc
1561 agacaaagag aagaaaggcc tggagagtcg tgcggacagc attgggagcg gccgagccat
1621 cccaattaaa cagggcatgc tgttgaagcg aagtggcaaa tcgttgaata aagagtggaa
1681 aaagaaatat gtcaccctgt gtgacaatgg cgtgctgacc tatcatccca gtttacatga
1741 ttacatgcag aatgttcatg gtaaggagat tgaccttctg agaaccactg tgaaagtccc
1801 agggaagagg ccaccccgag ccacgtcagc ctgcgcaccc atctccagcc ctaaaaccaa
1861 tggcctatcc aaggacatga gcagtttaca catctcaccc aattcagaca cagggctggg
1921 tgactccgta tgctccagcc ccagtatctc cagcaccacc agccccaagc tcgacccgcc
1981 cccctcccct cacgccaaca gaaagaagca ccgaaggaag aaaagcacta gcaacttcaa
2041 agccgacggc ctgtccggca ctgctgaaga acaagaagaa aattttgagt ttatcattgt
2101 gtccctcact ggccaaacat ggcactttga agccacgacg tatgaggagc gggacgcctg
2161 ggtccaagcc atcgagagcc agatcctggc cagcctgcag tcgtgcgaga gcagcaagaa
2221 caagtcccgg ctgacgagcc agagcgaggc catggccctg cagtcgatcc ggaacatgcg
2281 cgggaactcc cactgtgtgg actgcgagac ccagaatccc aactgggcca gtttgaactt
2341 gggagccctc atgtgcatcg aatgctcagg gatccaccgg aatcttggca cccacctttc
2401 ccgagtccga tctctggacc tggatgactg gccaatcgag ctcatcaagg tgatgtcatc
2461 catcgggaac gagctagcca acagcgtctg ggaagagagc agccaggggc ggacgaaacc
2521 atcggtagac tccacaaggg aagagaagga acggtggatc cgtgccaagt acgagcagaa
2581 gctcttcctg gccccgctgc cctgcacgga gctgtccctg ggccagcacc tgctgcgggc
2641 caccgccgac gaggacctgc ggacggccat cctgctgctg gcacacggct cccgggacga
2701 ggtgaacgag acctgcgggg agggagacgg ccgcacggcg ctgcatctgg cctgccgcaa
2761 ggggaatgtg gtcctggcgc agctcctgat ctggtacgga gtggacgtca cggcccgaga
2821 tgcccacggg aacacagctc tggcctacgc ccggcaggcc tccagccagg agtgcatcga
2881 cgtgctgctg cagtacggct gccccgacga gcgcttcgtg ctcatggcca cccctaacct
2941 gtccaggaga aacaataacc ggaacaacag cagtgggagg gtgcccacca tcatctgagg
3001 aacagccgtg cccgcctgct cgccgcacct gggacgcggc agcctcgccg cattctcgct
3061 cagaagtcgc agcacgtgag tcccgtcgca tcccctccct cttcctggtg gccacctccc
3121 tcccgcccac ccactctcac cccaaacaaa atcacaaaac ctggacatcc ctcaaggggc
3181 gaagaggcgg ccgggagact gcagaagtgg ctccttttca taaactcccc taaaccacac
3241 acaggagaga gcgacgggcc tcggcccttt gatgatagca catggcgcag gacccttgtc
3301 ctggtggcac aagggatggg gacgcgaggg ggaggggagg cgaggaacaa ggagaagggg
3361 caactttcct taactggcag ttgagcacat agtacatttc ccctctacca aacggaacac
3421 ttggattcca tctcttctct gaggagctcg acggcataaa tcagaagcaa gcacagagtt
3481 tgtcaggttt gaagccccta tgatggtgtg tgtcaaatca gttgtagcta atctgtccag
3541 ggagaatact ggcttcatta cacttgtaca gccgagttct tcccgcatta ctgctgttta
3601 atagaacgtg attagtcatc gccgagaaga aagcatatta gccgaggagg tagtcacgcg
3661 gcacgcgccg gtgattgcca cgatgtgatt gcaatactct tagaagcacc atattatccc
3721 agacatgttc tttcaagccc ttggagccct ctctaaattc actgtcatca tttagtatct
3781 gtttaatttt tcagtccaaa gagaggaaat cagtcgctga gtattatttg actccggtct
3841 ccttggtgca aaaacaaaat gggaaaaata aataagaata actcagaaac tcaaaaggaa
3901 accacaaatt cagctaataa tagcatttcg agtatatttc gtaaactaag gaaatacaca
3961 aaaggctgtt tttttccgac tgtaagagat atttgatgtc cttttgccga ggtggatgtg
4021 ttagtctcag gccctcctgg accacgttgc ccaagtcaca caggcttctg tgttatgtat
4081 ttagataaga tgtgtgaaaa tatatttgaa taaaagaagt tcataaaaaa aaaaaaaaaa
4141 a
//