LOCUS BC157874 3559 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens transmembrane channel-like 3, mRNA (cDNA clone
MGC:189768 IMAGE:9057092), complete cds.
ACCESSION BC157874
VERSION BC157874.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3559)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3559)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-DEC-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 684 Row: p Column: 18.
FEATURES Location/Qualifiers
source 1..3559
/db_xref="H-InvDB:HIT000503429"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:189768 IMAGE:9057092"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GTGGCACC"
gene 1..3559
/gene="TMC3"
/db_xref="GeneID:342125"
/db_xref="HGNC:HGNC:22995"
CDS 50..3352
/gene="TMC3"
/codon_start=1
/product="transmembrane channel-like 3"
/protein_id="AAI57875.1"
/db_xref="GeneID:342125"
/db_xref="HGNC:HGNC:22995"
/translation="MKTSKASQRYRGIRRNASQCYLYQESLLLSNLDDSFSADETGDS
NDPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAG
AELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTG
AFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERK
IGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWD
YLIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLLSLAGSI
YLIYFVVDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTL
RFQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFATRTAPEE
EKWSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEM
LKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLHLVY
NQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAML
LFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISS
PVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQ
EESTKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQSMPQSPRPG
DRAPSSPLPGVPKSRLEHETNRYLHGLCASTSDLHRNRSRTPMTFTTHIEDVHSEPLF
RKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINECDSYKKKHLNVWPERHFKIDAS
GDIVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPPRSLIDLRRAPHF
YIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAYVPKKPRSRNFQYPQPPLKPRG
KPRFEPSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRRKAKSGQEL
TVDLDDLICSNV"
BASE COUNT 928 a 937 c 893 g 801 t
ORIGIN
1 accgtccgtc tctggccagc ttctgattgt tagcagtggg ttagctccca tgaaaacctc
61 gaaggcatcc cagcgctata gaggcatccg gagaaatgcc agccagtgct acctctacca
121 ggaatctctg ctgctcagca acttggatga cagctttagt gctgatgaaa caggggacag
181 caatgatccg gaacaaatct tccagaatat acagttccag aaagatctca tggcaaacat
241 tcgctgcaga ccctggacta tgggacagaa gctgagggca ttgagacaag cgaagaacat
301 tgtgctgaag tttgaaggga ggctgaccag gacccgaggc taccaagcag caggtgcaga
361 gctctggcgg aaatttgctc gtctcgcctg taactttgtg gtcatcttca ttccctggga
421 aatgaggata aagaaaatcg agagtcattt tggatctggc gttgcctcct atttcatatt
481 cttgagatgg ttatttggaa ttaatattgt gctcaccatt atgacaggtg cttttattgt
541 cattccagag ctgattgcag gccagccctt tggaagcaca gccaggaaga ccatccccaa
601 ggagcaggtt tcgtctgccc aagacctgga caccgtctgg tctctggggg gctacctcca
661 gtactctgtc ctcttctacg gatattacgg cagggagagg aagatcggga gagctggcta
721 ccggctgccc ttggcgtatt tcctagtggg gatggcagtg tttgcttaca gcttcatcat
781 tcttttaaaa aagatggcta agaactcccg cacgagtctt gccagtgctt ccaatgaaaa
841 ctataccttc tgctggcggg tgttctgtgc ctgggattac ctcattggaa acccagaggc
901 tgcagagagc aaaacagctg ccatagtgaa cagcatcagg gaagctatat tggaagaaca
961 ggagaaaaag aaaagcaaaa acctggcagt gaccatctgc ctgaggatta ttgccaacat
1021 cctggtgctt ctctcactgg ctgggagcat ttatctcatc tactttgtgg tggaccggtc
1081 ccagaagctg gagcagtcga agaaggagct gacactttgg gaaaagaatg aggtcagtgt
1141 ggtggtctcc ctcgtcacca tgatagcacc atcagccttt gacctcattg ctgccttaga
1201 gatgtaccac cccaggacca cgctgcgctt ccagcttgca agggtccttg tgctgtattt
1261 gggaaatctc tacagcctga tcattgctct cctggacaaa gttaacagca tgagcattga
1321 ggaaatggct accaaaaata acacaagtca ttggatagat tccaccacct tctttgcaac
1381 caggacagcc cctgaagaag agaaatggtc cacatctcgg cctggaatgg ggctcaggag
1441 aaacaacaca tgggccttgg aagagaccag catttcagct tataccatgc ctcttataaa
1501 ggccaacaag actagcctcc acactcagag tccacaagac cagtgctggg agacatacgt
1561 tggtcaggag atgctgaagc tctccatcat tgacatgctc ttcaccgtgg cgagcattct
1621 gctcatagac ttcttccgag gacttttcgt gcggtactta agtgactact ggtgttggga
1681 tctggaaagc aagtttcctg aatatggaga attcaaaata gctgagaatg tgctacattt
1741 agtctacaac caaggaatga tttggatggg ggccttcttc tccccatgtc tcccagcgtt
1801 caacgttctc aaactcattg ggctcatgta cctgagaagc tgggctgtgc tgacctgcaa
1861 tgtgccccac cagcaagtat ttcgagcctc aagatccaac aacttctact tggcaatgct
1921 cctgtttatg ctgtttctgt gcatgctgcc aaccattttt gctattgtcc gatacaagcc
1981 atctctaaac tgtgggccat tcagtggaca agagaaaatt tatgacattg tgtcagaaac
2041 gattgagaaa gactttcctg tgtggtttgg ctccgtggtt ggacacatca gtagccccgt
2101 ggtcatcctg cccgcagtac tcctgctttt catgctcatc tattatctcc agagcatcgc
2161 acggtctcta aagctcagca accaccagct caaaatgcag atccaaaacg caagatcaga
2221 ggataagaaa aaggttgccc agatggtaga agcccgaatc cagacccagg aagaaagcac
2281 caagaagctt ccaaacgaca gtgatcttac cagccagctg tcctcagcgc actcgggcac
2341 accccaaaac aacggcaacg tggcccattt tgactcaggg agcagcaaga gtggcaggat
2401 agagacagtc gcacagtcca tgccccagag cccgaggcca ggggacaggg ctcctagctc
2461 acctctccct ggggtcccca aatccaggct agagcatgaa actaacaggt atctgcacgg
2521 tctgtgtgca agcaccagtg accttcacag gaacagatcg cgcacaccta tgacatttac
2581 aacgcacatc gaagatgtac actcagaacc tcttttccga aaagactttc agcaaatcaa
2641 ccctcctcac cgtggaccac aggcctcgac tttgctggca cagggtccca ggccccacgc
2701 ccccagatac tatgtcatta atgaatgtga ctcttacaag aaaaaacatc taaatgtctg
2761 gccagaaaga catttcaaga tagatgcttc aggtgacatt gtggagctgt accccaggaa
2821 cgtgcgacaa tatgcatccc gggtcccccg ccagcctccc tccccacagc tgagtgaaga
2881 agaggaggag acgccaagca gagattggat caaacggtct cttcccccac gctccctgat
2941 agacctccgt cgggctcctc atttttatat tggggagagg tccgaaagtc agacccggga
3001 tcccgagcac caggggaggg tgcactacaa gtcgtggaat gaagattttg agggtcacct
3061 tgagaggcca gcctatgtgc ccaaaaagcc acgatcccgg aatttccaat acccacagcc
3121 ccctctgaag cccagaggga agcccaggtt cgagccatcc ctcacggaat ctgactccgt
3181 gtcggcagca tccagcagtg accagcagaa cagcagcgct gaccagtacc tgcaggtcac
3241 ccacagccag ggcaggttcc cgaggtccgt gggccagccc agcaggagga aggccaagtc
3301 ggggcaggag ctgaccgtgg atctggatga cttgatttgt tcaaatgtct aggcttcctc
3361 cagtgtcccg ttcctagagg tcaggcccct gttggagtgc tgggccagca catggcatct
3421 ccctttctgg aaaaagaggt gaacaagtgt gttagagacc tgaggggcat ggtcagcggc
3481 tgctagctga ggccctgagg ctgacagggc tacagatacc tattctacag ctactgttag
3541 ccaaatttat ccgagttag
//