LOCUS BC157841 4395 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens T-box 18, mRNA (cDNA clone MGC:189736 IMAGE:9057060),
complete cds.
ACCESSION BC157841
VERSION BC157841.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4395)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4395)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-DEC-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 684 Row: o Column: 10.
FEATURES Location/Qualifiers
source 1..4395
/db_xref="H-InvDB:HIT000503396"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:189736 IMAGE:9057060"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: AAGGTTAC"
gene 1..4395
/gene="TBX18"
/db_xref="GeneID:9096"
/db_xref="HGNC:HGNC:11595"
/db_xref="MIM:604613"
CDS 49..1872
/gene="TBX18"
/codon_start=1
/product="T-box 18"
/protein_id="AAI57842.1"
/db_xref="GeneID:9096"
/db_xref="HGNC:HGNC:11595"
/db_xref="MIM:604613"
/translation="MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAE
EAARAVDDGGCSRGGGAGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCED
GFQQGASPLASPGGSPKGSPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMI
ITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPV
PPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKD
CGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRN
RMGLEALVESYAFWRPSLRTLTFEDIPGIPKQGNASSSTLLQGTGNGVPATHPHLLSG
SSCSSPAFHLGPNTSQLCSLAPADYSACARSGLTLNRYSTSLAETYNRLTNQAGETFA
PPRTPSYVGVSSSTSVNMSMGGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAF
ATNQTHQGSYNTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPSGTMTDR
QMLPPVEGVHLLSSGGQQSFFDSRTLGSLTLSSSQVSAHMV"
BASE COUNT 1234 a 929 c 966 g 1266 t
ORIGIN
1 gtagaagctg tatatgagag aggggcgggc gggcgcgggg cgggggggat ggccgagaag
61 cgaaggggct cgccgtgcag catgctaagc ctcaaggcgc acgctttctc ggtggaggcg
121 ctgatcggcg ccgagaagca gcaacagctt cagaagaagc ggcgaaaact gggcgccgaa
181 gaggcggcga gggccgtgga cgacggaggc tgcagccgcg gcggcggcgc gggcgaaaag
241 ggttcttctg agggagacga aggcgctgcg ctcccgccgc cggctggggc gacgtctggg
301 ccggctcgga gtggcgcaga cctggagcgc ggagccgcgg gcggctgtga ggacggcttc
361 cagcagggag cttcccctct ggcgtcaccg ggaggctccc ccaaggggtc tccggcgcgc
421 tccctggccc ggcccgggac ccctctgccc tcgccgcagg ccccgcgggt ggatctgcag
481 ggagccgagc tctggaagcg ctttcatgag ataggcactg agatgatcat caccaaggcc
541 ggcaggcgca tgtttccagc aatgagagtg aagatctctg gattagatcc tcaccagcaa
601 tattacattg ccatggatat tgtaccagtg gacaacaaaa gatacaggta tgtttaccac
661 agttcgaaat ggatggtggc aggtaatgct gactcgcctg tgccaccccg tgtgtacatt
721 catccagact cgcctgcctc gggggagact tggatgagac aagttatcag cttcgacaag
781 ctgaagctca ccaacaatga actggatgac caaggccata ttattcttca ttctatgcac
841 aaataccaac cgcgagtgca cgtcatccgt aaagactgtg gagacgatct ttctcccatc
901 aagcctgttc catccgggga gggagtaaag gcattctcct ttccagaaac tgtcttcaca
961 accgtcactg cctatcagaa tcagcagatt actcgcctga agatagatag gaatccattt
1021 gctaaaggct tccgagactc cgggcgcaac agaatgggtt tggaagcctt ggtggaatca
1081 tatgcattct ggcgaccatc actacggact ctgacctttg aagatatccc tggaattccc
1141 aagcaaggca atgcaagttc ctccaccttg ctccaaggta ctgggaatgg cgttcctgcc
1201 actcaccctc accttttgtc tggctcctct tgctcctctc ctgccttcca tctggggccc
1261 aacaccagcc agctgtgtag tctggcccct gctgactatt ctgcctgtgc ccgctcaggc
1321 ctcaccctca accgatacag cacatctttg gcagagacct acaacaggct caccaaccag
1381 gctggtgaga cctttgcccc gcccaggact ccctcctatg tgggcgtgag cagcagcacc
1441 tccgtgaaca tgtccatggg tggcactgat ggggacacct tcagctgccc acagaccagc
1501 ttatccatgc agatttcggg aatgtccccc cagctccagt atatcatgcc atcaccctcc
1561 agcaatgcct tcgccactaa ccagacccat cagggttcct ataatacttt tagattacac
1621 agcccctgtg cactatatgg atataacttc tccacatccc ccaaactggc tgccagtcct
1681 gagaaaattg tttcttccca aggaagtttc ttggggtcct caccgagtgg gaccatgacg
1741 gatcggcaga tgttgccccc tgtggaagga gtgcacctgc ttagcagtgg gggtcagcag
1801 agtttctttg actctaggac cctaggaagc ttaactctgt catcatctca agtatctgca
1861 catatggtct gatgaagcct ttaagttaaa tgacatttgg atctgtctaa catattttct
1921 ttttcttttt taaaagctat gtggaaagaa actctctgtg gtttataaaa tgtacatata
1981 atagaaaatg aaggctcact gggttttttg actttatcat ggtgagattg taattatcta
2041 tggtatatat gtatgctgta tatacatagc acatggagta tcacggcccc tattgttccc
2101 ctgtttcatc cagttgcacg gagtattggc atgcgtgtag tatgtttaag caaagttctc
2161 agactctttt aaaaacaaga tggtaaactt aaaacttggc aattatacta tccagaagaa
2221 cacttataac ttaatttatc agaaaaatgc tctaaacggt ttcatacttg atgtattgat
2281 aaccagcagt aaccagcatg tagagtcttg tgatttctgt tattcttgga cacagtgtga
2341 gaatctaaaa tacaaaagcc agttgaagtc ttagtgttag tcctgaggta tttgtaatca
2401 tgaaggatca gctttttcat tcctgcttat tatttaccac acatactata tgaccttggg
2461 tctataaaaa aatcataacc cataataatt gttattttct taaggaaggt aaaggagagg
2521 cttgtgattt ttttttttac actttccatt gggcacataa gaggttctta ttcatctgta
2581 gagaacaaat ttccagtatt ttcgattttt tgcttatttt atatatcaaa tagaccatta
2641 aagaatgttc tataaacatt tttaaattcc aattttcacc aggggaggaa tatgtgatat
2701 gagtggaatg gcaaaaggaa aataaatcca cctcaaattc attgattcca atgagaaatg
2761 tctatctttt aaatcaagag taatactatt gttaactata ccttatgttt ttgtatagtt
2821 tgtttttaaa tttagaatat tttttccatc ttgctctgag cttcctgacc gatagtatat
2881 aagtaaaaaa aatgcattta tgctacttat ttatatcttg taattcctac acattgaacc
2941 cttttcccct tcttaacctt gtccgtctgc ctgagtcttt cccaaaacag atagttccta
3001 ggcctgtatg gtgttaaata acacggtgag gaatttcagt aggttatctc cagcaatctg
3061 tcttttggga gctatagtgc aaaggccaaa gcccattact ataaagaccc tcttggagga
3121 ctaagaagga agatactaat tatgataaag gaactataaa acttttaacc tcaacagaat
3181 ttgtaatgtc agaactggag aaattaaaat cagtattaaa ttttttaatt cctaaaataa
3241 tatatgcatg gttgaagagt taaaaacaag taactttgag agcacagtat gagataaata
3301 aaaaaggcta agaatacatg atgaggcaca ttccccttct gaggagaaag cgaaataaca
3361 tgtctgtgca ttgacccatt cattacattt catgtatctt aagcaaaaga gcatgatttt
3421 ctctcattgc taaaaagagt tgctttaact catccctgga tttggtgggg aaagggtaca
3481 actcctgatt tgctgtttca ctttgaaaca acacaatttg ttagatactt agggagatat
3541 actgttgaat ttgcacagga tgtgactctg tttatacata ttaacaaatt tccttttgga
3601 ttccttagca gttcatcaaa ttagtattaa atttttaaat ttaaaactag catgaaggga
3661 catgaaatat ttgcagtagg tggatctatg taagatgttt gggtatggca ttaatagctt
3721 gacaaagatt tggggaaagg tgttaagaat gagtccatct cagccaatag tgcttggtgt
3781 ataattcaag aacagagagt tttccatctt gaaaaaacat ggaaagtaat gctctatacc
3841 catatgtatt aataagagca ttttccttct tgccgttgat catttcagat gataccacaa
3901 tatgagtata attttttatt aatctttttt ctggtaaaat tttagcaata ttgtacaaat
3961 gcttttttta ggttttactg taaatattaa tcaccacgtc acttcagaga ctagcctttt
4021 attgctgaat taaatgacat gcatacattg ataattatat atctgtattt tattaaaaag
4081 tacttaaaat tatattaaaa tatgttatta aaccctttta tgattttgga gggtaatcat
4141 tttaatgtct aaaaatattg atccaagaat aagcacacac atgcataccc caaacgcaaa
4201 ttctgtacct ctcaaataca tggcagaaag aaatgggcct gctgttcatg tttcatgtgt
4261 taaatgtaat ttcttggtgt gttgaccatg tcattgaagg tgaaggccct gacaaatgtt
4321 gaacacatga aaatttgaat gtgagaggaa agggatgggg tggtatgttt tgttttgggt
4381 ccaggggaga aaggc
//