LOCUS BC152450 6006 bp mRNA linear HUM 23-AUG-2007
DEFINITION Homo sapiens eukaryotic translation initiation factor 2C, 4, mRNA
(cDNA clone MGC:176703 IMAGE:8862582), complete cds.
ACCESSION BC152450
VERSION BC152450.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6006)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6006)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 15 Row: g Column: 4.
FEATURES Location/Qualifiers
source 1..6006
/db_xref="H-InvDB:HIT000436041"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176703 IMAGE:8862582"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+; Clone identification
sequence tag: NA"
gene 1..6006
/gene="EIF2C4"
/gene_synonym="AGO4"
/db_xref="GeneID:192670"
/db_xref="HGNC:HGNC:18424"
/db_xref="MIM:607356"
CDS 191..2776
/gene="EIF2C4"
/gene_synonym="AGO4"
/codon_start=1
/product="eukaryotic translation initiation factor 2C, 4"
/protein_id="AAI52451.1"
/db_xref="GeneID:192670"
/db_xref="HGNC:HGNC:18424"
/db_xref="MIM:607356"
/translation="MEALGPGPPASLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDV
YHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDR
VDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLP
SMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQ
PIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTR
RPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVC
NIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIV
VHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAP
QKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQ
LIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGI
NNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQ
TSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVA
WPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDS
TITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRS
VSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQH
TMYFA"
BASE COUNT 1660 a 1273 c 1448 g 1625 t
ORIGIN
1 gagccggagc cgggtccctg tccccgggcc gggcgccgcc gccgccccct gcccagcgcc
61 cgcgtctccg cggcgccacc ccagcgccaa tattccggag atcaagcgtt acgcggcggc
121 ggcggcggcg gcggcggggc ccggagcggg aggcgccggg gaccggggcg aggcggcccc
181 cgccgccgcc atggaggcgc tgggacccgg acctccggct agcctgtttc agccacctcg
241 tcgtcctggc cttggaactg ttggaaaacc aattcgactg ttagccaatc attttcaggt
301 tcagattcct aaaatagatg tgtatcacta tgatgtggat attaagcctg aaaaacggcc
361 tcgtagagtc aacagggagg tagtagatac aatggtgcgg cacttcaaga tgcaaatatt
421 tggtgatcgg cagcctgggt atgatggcaa aagaaacatg tacacagcac atccactacc
481 aattggacgg gatagggttg atatggaggt gactcttcca ggcgagggta aagaccaaac
541 atttaaagtg tctgttcagt gggtgtcagt tgtgagcctt cagttgcttt tagaagcttt
601 ggctgggcac ttgaatgaag tcccagatga ctcagtacaa gcacttgatg ttatcacaag
661 acaccttccc tccatgaggt acaccccagt gggccgttcc tttttctcac ccccggaagg
721 ttactaccac cctctgggag ggggcaggga ggtctggttt ggttttcatc agtctgtgag
781 acctgccatg tggaatatga tgctcaacat tgatgtatct gcaactgctt tctaccgggc
841 tcagcctatc attgagttca tgtgtgaggt tttagacatt cagaacatca atgaacagac
901 caaacctcta acagactccc agcgtgtcaa atttaccaaa gaaatcagag gtctcaaagt
961 tgaggtgacc cactgtggac agatgaaacg aaaataccga gtttgtaatg tgactagacg
1021 gccagccagt catcaaactt ttcctttgca gctagaaaac ggtcaagcta tggaatgtac
1081 agtagctcaa tattttaagc aaaagtatag tctgcaactg aaataccccc atcttccctg
1141 tctccaagtg ggacaagaac aaaagcatac atacttgcca ctcgaggtct gtaatatagt
1201 ggcaggacag cgatgtatca agaagctcac agacaatcag acttccacaa tgatcaaagc
1261 tacagcaaga tctgctcctg acagacagga agagatcagt agactggtga agagcaacag
1321 tatggtgggt ggacctgatc cataccttaa agaatttggt attgttgtcc acaatgaaat
1381 gacagagctc acaggcaggg tacttccagc accaatgctg caatatggag gccggaataa
1441 aacagtagcc acacccaacc agggtgtctg ggacatgcga ggaaagcagt tttatgctgg
1501 cattgaaatt aaagtttggg cagttgcttg ttttgcacct cagaaacaat gtagggaaga
1561 tttactaaag agtttcactg accagctgcg taaaatctct aaggatgcag gaatgcccat
1621 ccagggtcag ccatgtttct gcaagtatgc acaaggtgca gacagtgtgg agcctatgtt
1681 taaacatctg aaaatgactt atgtgggcct acagctaata gtggttatcc tgcctggaaa
1741 gacaccagta tatgcggagg tgaaacgtgt tggagatacc cttctaggta tggccacaca
1801 gtgtgtccag gtaaaaaatg tagtgaagac ctcacctcaa accctttcca atctttgcct
1861 gaagataaat gcaaaacttg gaggaattaa caatgtgctt gtgcctcatc aaaggccctc
1921 ggtgttccag cagcctgtca tcttcctggg agcggatgtc acacaccccc cagcagggga
1981 tgggaagaaa ccttccattg ctgctgtggt tggcagtatg gatggccacc ccagccggta
2041 ctgtgccacc gttcgggtgc agacttcccg gcaggagatc tcccaagagc tcctctacag
2101 tcaagaggtc atccaggacc tgactaacat ggttcgagag ctgctgattc agttctacaa
2161 atccacacgc ttcaaaccca ctcggatcat ctattaccgt ggaggggtat ctgagggaca
2221 aatgaaacag gtagcttggc cagaactaat agcaattcga aaggcatgta ttagcttgga
2281 agaagattac cggccaggaa taacttatat tgtggtgcaa aaaagacatc acacacgact
2341 cttctgtgca gataaaacag aaagggtagg gaaaagtggc aatgtaccag caggcactac
2401 agtggatagt accatcacac atccatctga gtttgacttt tacctctgta gtcatgcagg
2461 aattcaggga accagccgtc cctcacatta ccaggtcttg tgggatgaca actgcttcac
2521 tgcagatgaa ctccagctac tgacttacca gctgtgtcac acctatgtga ggtgcactcg
2581 ctcagtctct attccagccc ctgcatatta tgcccggctt gtagcattta gggcaaggta
2641 tcatctggtg gataaagatc atgacagtgc ggaaggcagt catgtgtcag gacagagcaa
2701 cggccgggat cctcaggcct tggctaaggc tgtgcaaatc caccatgata cccagcacac
2761 gatgtatttt gcctgagagt ctcagaaaaa gaactcaacc aatttggcac cccatgcagc
2821 ctcaaaatgt ttcaaatgcc taccgcctct agatcgagcc acgttgactt caggtggtct
2881 tctaccagca gctcggaata gttgcactga atctatactt tgcagcactg tctgatgcgt
2941 caacaaaatt gagccatttt tttaaagtaa tagatactaa tagattatct tttctgatgc
3001 actggactga atttttacct caatgtgcaa aggctgatca gcctgaactt tctaaaggac
3061 tttacaagaa gggtttctat ggaatatttt gctagctgtg gtgttcaccg catccctcta
3121 gtcttagaag agaagattat tccttttttc tgtagtcatt gagtggggta tatgcataag
3181 tgggagagaa aaaccaaaca atctacttca gttcagtgta actatttaat tgtgtgggtc
3241 catagacttt ttaatgaaga tttctgactt tgccactgta aatgccttta atgagcatta
3301 atttttgaaa gttttacaga gttttattag ttttactact ttatcttatt gatctctgca
3361 gacttgtgct ggtgcaagta catgctgaca ggcaatttgc actatatttg gctgcagatt
3421 caaataggca gttctcttat ttggtcgact tttgtgaatg tgtgacataa acagatgtaa
3481 tgcatgtcac agtgacggag ataacactgc catgataaaa gtactcatgt ttcccctatt
3541 tggaaaaaaa aattgctttt agtatttttc caagttttca aaagtgccca ttttatgctg
3601 ctgtgtggtt tgttaaatct aaatgatttt taaacttttc tcatagaaac ttaactttgg
3661 caataaacat tttttaaggt ctctcctctt ccttccccaa caatgtagtt ttctagatga
3721 gatttcagta tgattttatc agctatttct tatatatcat aatctggcaa tttctgaaac
3781 cagtcagaaa agacatatat ttccatgcct ttttaaagaa ttatttttac ctgttttata
3841 ttcacagttg gtgtcctgtc actttgtttt aaaataagct agaaccagga tgcttcctta
3901 ttggaaaggc tttgccagtc cttaaggtac aatgagtgat gctgcaactt gcaaatgtac
3961 cagcatttaa aatttctttt cctgggaatc aaggtaactc acacgactac ttgcagtaca
4021 aattttttgc ttctctttcg acatgaaatg tacttggtgg gttttccttc cttttattaa
4081 actaaaactg tgtggaaaag gttgattttt cttaatagat tctggattcc actcacaggg
4141 agatgggatt cctttcttgt ccaaacaaag ggagttgctc taaagcgagc atcagttaaa
4201 atgtagggga aaatgtattc tgtatgtagt gtagataata ctttgtgaat ggacaacagt
4261 tacatagtgt cttggtagca ccagccagtg tttcccagcc cagagtttac tgacttgtaa
4321 ttctctatcc aggacatcag gagtgaggga tggaaaaggg gataaaaggc ctggagccac
4381 actctatatg gctgaggaag gagctaggga aagagataga cacaatgggg tgaaaacaat
4441 tttgccgccc ctgcctggaa actgctggtg gggaaatgat ggtgaagggt gtttgcttga
4501 actcatgaga cggtccaaat ctcataaact agccttctca aaatcccagc aatataaagc
4561 actgtttttc ttcagtcgtt taaataaact tgtaaataca ttgaagttta catttccatg
4621 tgctgttgat caacggcgcc acctgtgttt gctgagactg gtctctgaga gagttttatg
4681 tcgatcgagg cctgttgctc attaagctga gtgcagacgt ccttaatccc tgcagatagt
4741 gggatgaaag caagttctgt aaaatgaagc acaacatagc caggagtgaa gagatggcag
4801 atgttaattt cttaaaattt tccttttttt tttttttttt tgcaaatacc tcacttggat
4861 aatacaaatc aggacatgtt ggtgaggggc tggctgcttg gctgctgctt ttattcacac
4921 ttgttcaggg agagcacaga gaataccctt cagcatggcc actctggacc caagaggagg
4981 aaaaaacgga agctttttta ggagaaggag gacttgctgg aatccaagat gtgaagaact
5041 cttggtgact ggctggctgg ccagcgggca ccacacctgc acttgagtgc ctcgggcttg
5101 cttattaata acgcacagaa gaagcatcac ttctcaccat ctcctggcat gtatggagca
5161 gggagcaagg ctatgttccc gaaagccctg attagcttgt cttgctctac gctcgacctc
5221 gaacaataca gcttgtaaga cctcagtcag tcctggtaca ctggggtaaa tcagtgtggt
5281 ggtggaagaa aagccgggag gcctattttt ataggaaaat agtaccatta aaggtgcaat
5341 gctgtcattt tggacaaaag gaaagaaatt tggaagagct gggattattg gcaaaaactt
5401 gctgaggggt gaatctttag agctaatcac tgcagaatca gagttgcagc aatatgattg
5461 caagcaagtc tgaatgcata gttttacttt aattcggctt gacaatttga ataggtaacc
5521 ccctcgggac tgactgaatc gttatgcatg tgtcaatcaa tgggaggtgt gcattctcta
5581 gaagtagttt taggctgttt ggtttggttt tggttttgtt ttttaaatgc agcctgttga
5641 ggcactgtca tgtggtgtga aagatttaaa tgtagcaacg ctaaagagta ataatttggg
5701 gataagaagt ggggacattg gccgggcgcg gtggctcacg cctgtaattc cagcactttg
5761 ggaggcctag gtgggcggat cagctgaggt cgagagttcg aggccagtct gaccaacatg
5821 gtgaaacccc atctctacta aaaatacaga aaattagctg ggtctggtgg tggatgcctg
5881 taatcccagc tactcgggag gctgaggcag gagaattgct tgaacccagg aggtggacgg
5941 tgcagtgagc tattactcca gcctgggcaa caagagcgaa actctgtctc aaaaaaaaaa
6001 aaaaaa
//