LOCUS BC152425 4069 bp mRNA linear HUM 23-AUG-2007
DEFINITION Homo sapiens reticulon 4, mRNA (cDNA clone MGC:176660
IMAGE:8862539), complete cds.
ACCESSION BC152425
VERSION BC152425.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4069)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4069)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 15 Row: c Column: 9.
FEATURES Location/Qualifiers
source 1..4069
/db_xref="H-InvDB:HIT000436016"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176660 IMAGE:8862539"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+; Clone identification
sequence tag: NA"
gene 1..4069
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="Nogo-B"
/gene_synonym="Nogo-C"
/gene_synonym="NOGOC"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
CDS 135..3713
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="Nogo-B"
/gene_synonym="Nogo-C"
/gene_synonym="NOGOC"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/codon_start=1
/product="reticulon 4"
/protein_id="AAI52426.1"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTIS
AGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEV
SEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKL
VSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFER
VWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPST
PEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEK
NTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV
TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAV
PSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPEN
INAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSP
DSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKP
YLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRET
ETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTE
LPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKV
LVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLS
LTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELV
QKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALI
SLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
BASE COUNT 1205 a 922 c 922 g 1020 t
ORIGIN
1 caccacagta ggtccctcgg ctcagtcggc ccagcccctc tcagtcctcc ccaaccccca
61 caaccgcccg cggctctgag acgcggcccc ggcggcggcg gcagcagctg cagcatcatc
121 tccaccctcc agccatggaa gacctggacc agtctcctct ggtctcgtcc tcggacagcc
181 caccccggcc gcagcccgcg ttcaagtacc agttcgtgag ggagcccgag gacgaggagg
241 aagaagagga ggaggaagag gaggacgagg acgaagacct ggaggagctg gaggtgctgg
301 agaggaagcc cgccgccggg ctgtccgcgg ccccagtgcc caccgcccct gccgccggcg
361 cgcccctgat ggacttcgga aatgacttcg tgccgccggc gccccgggga cccctgccgg
421 ccgctccccc cgtcgccccg gagcggcagc cgtcttggga cccgagcccg gtgtcgtcga
481 ccgtgcccgc gccatccccg ctgtctgctg ccgcagtctc gccctccaag ctccctgagg
541 acgacgagcc tccggcccgg cctccccctc ctcccccggc cagcgtgagc ccccaggcag
601 agcccgtgtg gaccccgcca gccccggctc ccgccgcgcc cccctccacc ccggccgcgc
661 ccaagcgcag gggctcctcg ggctcagtgg atgagaccct ttttgctctt cctgctgcat
721 ctgagcctgt gatacgctcc tctgcagaaa atatggactt gaaggagcag ccaggtaaca
781 ctatttcggc tggtcaagag gatttcccat ctgtcctgct tgaaactgct gcttctcttc
841 cttctctgtc tcctctctca gccgcttctt tcaaagaaca tgaatacctt ggtaatttgt
901 caacagtatt acccactgaa ggaacacttc aagaaaatgt cagtgaagct tctaaagagg
961 tctcagagaa ggcaaaaact ctactcatag atagagattt aacagagttt tcagaattag
1021 aatactcaga aatgggatca tcgttcagtg tctctccaaa agcagaatct gccgtaatag
1081 tagcaaatcc tagggaagaa ataatcgtga aaaataaaga tgaagaagag aagttagtta
1141 gtaataacat ccttcataat caacaagagt tacctacagc tcttactaaa ttggttaaag
1201 aggatgaagt tgtgtcttca gaaaaagcaa aagacagttt taatgaaaag agagttgcag
1261 tggaagctcc tatgagggag gaatatgcag acttcaaacc atttgagcga gtatgggaag
1321 tgaaagatag taaggaagat agtgatatgt tggctgctgg aggtaaaatc gagagcaact
1381 tggaaagtaa agtggataaa aaatgttttg cagatagcct tgagcaaact aatcacgaaa
1441 aagatagtga gagtagtaat gatgatactt ctttccccag tacgccagaa ggtataaagg
1501 atcgttcagg agcatatatc acatgtgctc cctttaaccc agcagcaact gagagcattg
1561 caacaaacat ttttcctttg ttaggagatc ctacttcaga aaataagacc gatgaaaaaa
1621 aaatagaaga aaagaaggcc caaatagtaa cagagaagaa tactagcacc aaaacatcaa
1681 acccttttct tgtagcagca caggattctg agacagatta tgtcacaaca gataatttaa
1741 caaaggtgac tgaggaagtc gtggcaaaca tgcctgaagg cctgactcca gatttagtac
1801 aggaagcatg tgaaagtgaa ttgaatgaag ttactggtac aaagattgct tatgaaacaa
1861 aaatggactt ggttcaaaca tcagaagtta tgcaagagtc actctatcct gcagcacagc
1921 tttgcccatc atttgaagag tcagaagcta ctccttcacc agttttgcct gacattgtta
1981 tggaagcacc attgaattct gcagttccta gtgctggtgc ttccgtgata cagcccagct
2041 catcaccatt agaagcttct tcagttaatt atgaaagcat aaaacatgag cctgaaaacc
2101 ccccaccata tgaagaggcc atgagtgtat cactaaaaaa agtatcagga ataaaggaag
2161 aaattaaaga gcctgaaaat attaatgcag ctcttcaaga aacagaagct ccttatatat
2221 ctattgcatg tgatttaatt aaagaaacaa agctttctgc tgaaccagct ccggatttct
2281 ctgattattc agaaatggca aaagttgaac agccagtgcc tgatcattct gagctagttg
2341 aagattcctc acctgattct gaaccagttg acttatttag tgatgattca atacctgacg
2401 ttccacaaaa acaagatgaa actgtgatgc ttgtgaaaga aagtctcact gagacttcat
2461 ttgagtcaat gatagaatat gaaaataagg aaaaactcag tgctttgcca cctgagggag
2521 gaaagccata tttggaatct tttaagctca gtttagataa cacaaaagat accctgttac
2581 ctgatgaagt ttcaacattg agcaaaaagg agaaaattcc tttgcagatg gaggagctca
2641 gtactgcagt ttattcaaat gatgacttat ttatttctaa ggaagcacag ataagagaaa
2701 ctgaaacgtt ttcagattca tctccaattg aaattataga tgagttccct acattgatca
2761 gttctaaaac tgattcattt tctaaattag ccagggaata tactgaccta gaagtatccc
2821 acaaaagtga aattgctaat gccccggatg gagctgggtc attgccttgc acagaattgc
2881 cccatgacct ttctttgaag aacatacaac ccaaagttga agagaaaatc agtttctcag
2941 atgacttttc taaaaatggg tctgctacat caaaggtgct cttattgcct ccagatgttt
3001 ctgctttggc cactcaagca gagatagaga gcatagttaa acccaaagtt cttgtgaaag
3061 aagctgagaa aaaacttcct tccgatacag aaaaagagga cagatcacca tctgctatat
3121 tttcagcaga gctgagtaaa acttcagttg ttgacctcct gtactggaga gacattaaga
3181 agactggagt ggtgtttggt gccagcctat tcctgctgct ttcattgaca gtattcagca
3241 ttgtgagcgt aacagcctac attgccttgg ccctgctctc tgtgaccatc agctttagga
3301 tatacaaggg tgtgatccaa gctatccaga aatcagatga aggccaccca ttcagggcat
3361 atctggaatc tgaagttgct atatctgagg agttggttca gaagtacagt aattctgctc
3421 ttggtcatgt gaactgcacg ataaaggaac tcaggcgcct cttcttagtt gatgatttag
3481 ttgattctct gaagtttgca gtgttgatgt gggtatttac ctatgttggt gccttgttta
3541 atggtctgac actactgatt ttggctctca tttcactctt cagtgttcct gttatttatg
3601 aacggcatca ggcacagata gatcattatc taggacttgc aaataagaat gttaaagatg
3661 ctatggctaa aatccaagca aaaatccctg gattgaagcg caaagctgaa tgaaaacgcc
3721 caaaataatt agtaggagtt catctttaaa ggggatattc atttgattat acgggggagg
3781 gtcagggaag aacgaacctt gacgttgcag tgcagtttca cagatcgttg ttagatcttt
3841 atttttagcc atgcactgtt gtgaggaaaa attacctgtc ttgactgcca tgtgttcatc
3901 atcttaagta ttgtaagctg ctatgtatgg atttaaaccg taatcatatc tttttcctat
3961 ctgaggcact ggtggaataa aaaacctgta tattttactt tgttgcagat agtcttgccg
4021 catcttggca agttgcagag atggtggagc tagaaaaaaa aaaaaaaaa
//