LOCUS BC152422 3912 bp mRNA linear HUM 23-AUG-2007
DEFINITION Homo sapiens leucyl-tRNA synthetase, mRNA (cDNA clone MGC:176655
IMAGE:8862534), complete cds.
ACCESSION BC152422
VERSION BC152422.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3912)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3912)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 15 Row: c Column: 4.
FEATURES Location/Qualifiers
source 1..3912
/db_xref="H-InvDB:HIT000436013"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176655 IMAGE:8862534"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+; Clone identification
sequence tag: NA"
gene 1..3912
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
CDS 168..3698
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/codon_start=1
/product="leucyl-tRNA synthetase"
/protein_id="AAI52423.1"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
/translation="MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKG
KYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACAD
KLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGI
MKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFV
RWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYP
SKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNM
SYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSV
PSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELK
IQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYM
EPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLG
WLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLG
IRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHL
SYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMR
LALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFA
SELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQT
LLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLK
NYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVI
ASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNS
LELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIR
QGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAV
FNVDLMSKKIHLTENGIRVDIGDTIIYLVH"
BASE COUNT 1195 a 723 c 929 g 1065 t
ORIGIN
1 ggctgtagtt agtaaggagc cggatgattg cctcagcagg tgtgaagcgt gtgctttagt
61 ttcgtgggag gcctggcatc cccgagaggg aggggaaagg taaccactcc tttgtggagg
121 tcgccagggt cattgtcgtg gatttgcaca gtcggctggg cggtgcaatg gcggaaagaa
181 aaggaacagc caaagtggac tttttgaaga agattgagaa agaaatccaa cagaaatggg
241 atactgagag agtgtttgag gtcaatgcat ctaatttaga gaaacagacc agcaagggca
301 agtattttgt aaccttccca tatccatata tgaatggacg ccttcatttg ggacacacgt
361 tttctttatc caaatgtgag tttgctgtag ggtaccagcg attgaaagga aaatgttgtc
421 tgtttccctt tggcctgcac tgtactggaa tgcctattaa ggcatgtgct gataagttga
481 aaagagaaat agagctgtat ggttgccccc ctgattttcc agatgaagaa gaggaagagg
541 aagaaaccag tgttaaaaca gaagatataa taattaagga taaagctaaa ggaaaaaaga
601 gtaaagctgc tgctaaagct ggatcttcta aataccagtg gggcattatg aaatcccttg
661 gcctgtctga tgaagagata gtaaaatttt ctgaagcaga acattggctt gattatttcc
721 cgccactggc tattcaggat ttaaaaagaa tgggtttgaa ggtagactgg cgtcgttcct
781 tcatcaccac tgatgttaat ccttactatg attcatttgt cagatggcaa tttttaacat
841 taagagaaag aaacaaaatt aaatttggga agcggtatac aatttactct ccgaaagatg
901 gacagccttg catggatcat gatagacaaa ctggagaggg tgttggacct caggaatata
961 ctttactcaa attgaaggtg cttgagccat acccatctaa attaagtggc ctgaaaggta
1021 aaaatatttt cttggtggct gctactctca gacctgagac catgtttggg cagacaaatt
1081 gttgggttcg tcctgatatg aagtacattg gatttgagac ggtgaatggt gatatattca
1141 tctgtaccca aaaagcagcc aggaatatgt cataccaggg ctttaccaaa gacaatggcg
1201 tggtgcctgt tgttaaggaa ttaatggggg aggaaattct tggtgcatca ctttctgcac
1261 ctttaacatc atacaaggtg atctatgttc tcccaatgct aactattaag gaggataaag
1321 gcactggtgt ggttacaagt gttccttccg actcccctga tgatattgct gccctcagag
1381 acttgaagaa aaagcaagcc ttacgagcaa aatatggaat tagagatgac atggtcttgc
1441 catttgagcc ggtgccagtc attgaaatcc caggttttgg aaatctttct gctgtaacca
1501 tttgtgatga gttgaaaatt cagagccaga atgaccggga aaaacttgca gaagcaaagg
1561 agaagatata tctaaaagga ttttatgagg gtatcatgtt ggtggatgga tttaaaggac
1621 agaaggttca agatgtaaag aagactattc agaaaaagat gattgacgct ggagatgcac
1681 ttatttacat ggaaccagag aaacaagtga tgtccaggtc gtcagatgaa tgtgttgtgg
1741 ctctgtgtga ccagtggtac ttggattatg gagaagagaa ttggaagaaa cagacatctc
1801 agtgcttgaa gaacctggaa acattctgtg aggagaccag gaggaatttt gaagccacct
1861 taggttggct acaagaacat gcttgctcaa gaacttatgg tctaggcact cacctgcctt
1921 gggatgagca gtggctgatt gaatcacttt ctgactccac tatttacatg gcattttaca
1981 cagttgcaca cctattgcag gggggtaact tgcatggaca ggcagagtct ccgctgggca
2041 ttagaccgca acagatgacc aaggaagttt gggattatgt tttcttcaag gaggctccat
2101 ttcctaagac tcagattgca aaggaaaaat tagatcagtt aaagcaggag tttgaattct
2161 ggtatcctgt tgatcttcgc gtctctggca aggatcttgt tccaaatcat ctttcatatt
2221 acctttataa tcatgtggct atgtggccgg aacaaagtga caaatggcct acagctgtga
2281 gagcaaatgg acatctcctc ctgaactctg agaagatgtc aaaatccaca ggcaacttcc
2341 tcactttgac ccaagctatt gacaaatttt cagcagatgg aatgcgtttg gctctggctg
2401 atgctggtga cactgtagaa gatgccaact ttgtggaagc catggcagat gcaggtattc
2461 tccgtctgta cacctgggta gagtgggtga aagaaatggt tgccaactgg gacagcctaa
2521 gaagtggtcc tgccagcact ttcaatgata gagtttttgc cagtgaattg aatgcaggaa
2581 ttataaaaac agatcaaaac tatgaaaaga tgatgtttaa agaagctttg aaaacagggt
2641 tttttgagtt tcaggccgca aaagataagt accgtgaatt ggctgtggaa gggatgcaca
2701 gagaacttgt gttccggttt attgaagttc agacacttct cctcgctcca ttctgtccac
2761 atttgtgtga gcacatctgg acactcctgg gaaagcctga ctcaattatg aatgcttcat
2821 ggcctgtggc aggtcctgtt aatgaagttt taatacactc ctcacagtat cttatggaag
2881 taacacatga ccttagacta cgactcaaga actatatgat gccagctaaa gggaagaaga
2941 ctgacaaaca acccctgcag aagccctcac attgcaccat ctatgtggca aagaactatc
3001 caccttggca acataccacc ctgtctgttc tacgtaaaca ctttgaggcc aataacggaa
3061 aactgcctga caacaaagtc attgctagtg aactaggcag tatgccagaa ctgaagaaat
3121 acatgaagaa agtcatgcca tttgttgcca tgattaagga aaatctggag aagatggggc
3181 ctcgtattct ggatttgcaa ttagaatttg atgaaaaggc tgtgcttatg gagaatatag
3241 tctatctgac taattcgctt gagctagaac acatagaagt caagtttgcc tccgaagcag
3301 aagataaaat cagggaagac tgctgtcctg ggaaaccact taatgttttt agaatagaac
3361 ctggtgtgtc cgtttctctg gtgaatcccc agccatccaa tggccacttc tcaaccaaaa
3421 ttgaaatcag gcaaggagat aactgtgatt ccataatcag gcgtttaatg aaaatgaatc
3481 gaggaattaa agacctttcc aaagtgaaac tgatgagatt tgatgatcca ctgttggggc
3541 ctcgacgagt tcctgtcctg ggaaaggagt acaccgagaa gacccccatt tctgagcatg
3601 ctgttttcaa tgtggacctc atgagcaaga aaattcatct gactgagaat gggataaggg
3661 tggatattgg cgatacaata atctatctgg ttcattaaac tcatgcacat tggagattta
3721 tcctggtttc ttaggaatac tactactctg attgtgtcta ctgattggct atcagaacct
3781 taggctggac ctaaatagat tgatttcatt tctaaccatc caattctgca tgtattcata
3841 attctatcaa gtcatctttg attcctggac ctaataaatt ttttttccct ttcaaaaaaa
3901 aaaaaaaaaa aa
//