LOCUS BC151214 3884 bp mRNA linear HUM 24-JUL-2007
DEFINITION Homo sapiens leucyl-tRNA synthetase, mRNA (cDNA clone MGC:164866
IMAGE:40148007), complete cds.
ACCESSION BC151214
VERSION BC151214.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3884)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3884)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: f Column: 13.
FEATURES Location/Qualifiers
source 1..3884
/db_xref="H-InvDB:HIT000435923"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:164866 IMAGE:40148007"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..3884
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
CDS 96..3626
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/codon_start=1
/product="leucyl-tRNA synthetase"
/protein_id="AAI51215.1"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
/translation="MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKG
KYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACAD
KLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGI
MKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFV
RWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYP
SKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNM
SYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSV
PSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELK
IQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYM
EPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLG
WLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLG
IRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHL
SYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMR
LALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFA
SELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQT
LLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLK
NYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVI
ASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNS
LELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIR
QGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAV
FNVDLMSKKIHLTENGIRVDIGDTIIYLVH"
BASE COUNT 1226 a 712 c 901 g 1045 t
ORIGIN
1 ctggcatccc cgagagggag gggaaaggta accactcctt tgtggaggtc gccagggtca
61 ttgtcgtgga tttgcacagt cggctgggcg gtgcaatggc ggaaagaaaa ggaacagcca
121 aagtggactt tttgaagaag attgagaaag aaatccaaca gaaatgggat actgagagag
181 tgtttgaggt caatgcatct aatttagaga aacagaccag caagggcaag tattttgtaa
241 ccttcccata tccatatatg aatggacgcc ttcatttggg acacacgttt tctttatcca
301 aatgtgagtt tgctgtaggg taccagcgat tgaaaggaaa atgttgtctg tttccctttg
361 gcctgcactg tactggaatg cctattaagg catgtgctga taagttgaaa agagaaatag
421 agctgtatgg ttgcccccct gattttccag atgaagaaga ggaagaggaa gaaaccagtg
481 ttaaaacaga agatataata attaaggata aagctaaagg aaaaaagagt aaagctgctg
541 ctaaagctgg atcttctaaa taccagtggg gcattatgaa atcccttggc ctgtctgatg
601 aagagatagt aaaattttct gaagcagaac attggcttga ttatttcccg ccactggcta
661 ttcaggattt aaaaagaatg ggtttgaagg tagactggcg tcgttccttc atcaccactg
721 atgttaatcc ttactatgat tcatttgtca gatggcaatt tttaacatta agagaaagaa
781 acaaaattaa atttgggaag cggtatacaa tttactctcc gaaagatgga cagccttgca
841 tggatcatga tagacaaact ggagagggtg ttggacctca ggaatatact ttactcaaat
901 tgaaggtgct tgagccatac ccatctaaat taagtggcct gaaaggtaaa aatattttct
961 tggtggctgc tactctcaga cctgagacca tgtttgggca gacaaattgt tgggttcgtc
1021 ctgatatgaa gtacattgga tttgagacgg tgaatggtga tatattcatc tgtacccaaa
1081 aagcagccag gaatatgtca taccagggct ttaccaaaga caatggcgtg gtgcctgttg
1141 ttaaggaatt aatgggggag gaaattcttg gtgcatcact ttctgcacct ttaacatcat
1201 acaaggtgat ctatgttctc ccaatgctaa ctattaagga ggataaaggc actggtgtgg
1261 ttacaagtgt tccttccgac tcccctgatg atattgctgc cctcagagac ttgaagaaaa
1321 agcaagcctt acgagcaaaa tatggaatta gagatgacat ggtcttgcca tttgagccgg
1381 tgccagtcat tgaaatccca ggttttggaa atctttctgc tgtaaccatt tgtgatgagt
1441 tgaaaattca gagccagaat gaccgggaaa aacttgcaga agcaaaggag aagatatatc
1501 taaaaggatt ttatgagggt atcatgttgg tggatggatt taaaggacag aaggttcaag
1561 atgtaaagaa gactattcag aaaaagatga ttgacgctgg agatgcactt atttacatgg
1621 aaccagagaa acaagtgatg tccaggtcgt cagatgaatg tgttgtggct ctgtgtgacc
1681 agtggtactt ggattatgga gaagagaatt ggaagaaaca gacatctcag tgcttgaaga
1741 acctggaaac attctgtgag gagaccagga ggaattttga agccacctta ggttggctac
1801 aagaacatgc ttgctcaaga acttatggtc taggcactca cctgccttgg gatgagcagt
1861 ggctgattga atcactttct gactccacta tttacatggc attttacaca gttgcacacc
1921 tattgcaggg gggtaacttg catggacagg cagagtctcc gctgggcatt agaccgcaac
1981 agatgaccaa ggaagtttgg gattatgttt tcttcaagga ggctccattt cctaagactc
2041 agattgcaaa ggaaaaatta gatcagttaa agcaggagtt tgaattctgg tatcctgttg
2101 atcttcgcgt ctctggcaag gatcttgttc caaatcatct ttcatattac ctttataatc
2161 atgtggctat gtggccggaa caaagtgaca aatggcctac agctgtgaga gcaaatggac
2221 atctcctcct gaactctgag aagatgtcaa aatccacagg caacttcctc actttgaccc
2281 aagctattga caaattttca gcagatggaa tgcgtttggc tctggctgat gctggtgaca
2341 ctgtagaaga tgccaacttt gtggaagcca tggcagatgc aggtattctc cgtctgtaca
2401 cctgggtaga gtgggtgaaa gaaatggttg ccaactggga cagcctaaga agtggtcctg
2461 ccagcacttt caatgataga gtttttgcca gtgaattgaa tgcaggaatt ataaaaacag
2521 atcaaaacta tgaaaagatg atgtttaaag aagctttgaa aacagggttt tttgagtttc
2581 aggccgcaaa agataagtac cgtgaattgg ctgtggaagg gatgcacaga gaacttgtgt
2641 tccggtttat tgaagttcag acacttctcc tcgctccatt ctgtccacat ttgtgtgagc
2701 acatctggac actcctggga aagcctgact caattatgaa tgcttcatgg cctgtggcag
2761 gtcctgttaa tgaagtttta atacactcct cacagtatct tatggaagta acacatgacc
2821 ttagactacg actcaagaac tatatgatgc cagctaaagg gaagaagact gacaaacaac
2881 ccctgcagaa gccctcacat tgcaccatct atgtggcaaa gaactatcca ccttggcaac
2941 ataccaccct gtctgttcta cgtaaacact ttgaggccaa taacggaaaa ctgcctgaca
3001 acaaagtcat tgctagtgaa ctaggcagta tgccagaact gaagaaatac atgaagaaag
3061 tcatgccatt tgttgccatg attaaggaaa atctggagaa gatggggcct cgtattctgg
3121 atttgcaatt agaatttgat gaaaaggctg tgcttatgga gaatatagtc tatctgacta
3181 attcgcttga gctagaacac atagaagtca agtttgcctc cgaagcagaa gataaaatca
3241 gggaagactg ctgtcctggg aaaccactta atgtttttag aatagaacct ggtgtgtccg
3301 tttctctggt gaatccccag ccatccaatg gccacttctc aaccaaaatt gaaatcaggc
3361 aaggagataa ctgtgattcc ataatcaggc gtttaatgaa aatgaatcga ggaattaaag
3421 acctttccaa agtgaaactg atgagatttg atgatccact gttggggcct cgacgagttc
3481 ctgtcctggg aaaggagtac accgagaaga cccccatttc tgagcatgct gttttcaatg
3541 tggacctcat gagcaagaaa attcatctga ctgagaatgg gataagggtg gatattggcg
3601 atacaataat ctatctggtt cattaaactc atgcacattg gagatttatc ctggtttctt
3661 aggaatacta ctactctgat tgtgtctact gattggctat cagaacctta ggctggacct
3721 aaatagattg atttcatttc taaccatcca attctgcatg tattcataat tctatcaagt
3781 catctttgat tcctggacct aataaatttt ttttcccttt caaaaaaaaa aaaaaaaaaa
3841 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//