LOCUS BC150597 6211 bp mRNA linear HUM 11-FEB-2009
DEFINITION Homo sapiens tetratricopeptide repeat, ankyrin repeat and
coiled-coil containing 1, mRNA (cDNA clone MGC:183507
IMAGE:9056967), complete cds.
ACCESSION BC150597
VERSION BC150597.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6211)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6211)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Ambion
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 684 Row: k Column: 13
single stranded.
FEATURES Location/Qualifiers
source 1..6211
/db_xref="H-InvDB:HIT000503293"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:183507 IMAGE:9056967"
/tissue_type="Testicle, PCR rescued clones"
/clone_lib="NIH_MGC_382"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CGTACTAT"
gene 1..6211
/gene="TANC1"
/gene_synonym="ROLSB"
/gene_synonym="TANC"
/db_xref="GeneID:85461"
/db_xref="HGNC:HGNC:29364"
/db_xref="MIM:611397"
CDS 116..4288
/gene="TANC1"
/gene_synonym="ROLSB"
/gene_synonym="TANC"
/codon_start=1
/product="TANC1 protein"
/protein_id="AAI50598.1"
/db_xref="GeneID:85461"
/db_xref="HGNC:HGNC:29364"
/db_xref="MIM:611397"
/translation="MLKAVLKKSREGGKGGKKEAGSDFGPETSSVLHLDHSADSPVSS
LPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPG
DAVIMPFREVAKPTEPDEHAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDK
NETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTL
ESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEET
TGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAP
LRTSIRLPWHNTAGARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLR
NTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDL
HFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTC
LVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLT
NLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRAN
FQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIG
KVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQ
SAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRR
DKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGH
HILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILG
GANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGH
MKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKS
HALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCE
LLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAAC
EGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGR
TPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKL
GNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDM
RPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRYR
NSWQLWLTCKRL"
BASE COUNT 1685 a 1582 c 1589 g 1355 t
ORIGIN
1 ctgggcagga acgtctctca ggagaaagag tggaagagaa aattgtgaac taaggccccc
61 tgcccccttt tcctggtgca tgtgaagtta tcaaaaacag aaacaagtgt tgaaaatgtt
121 aaaggctgtg ctgaagaaga gccgagaggg aggaaaggga ggcaagaagg aagcaggaag
181 tgactttggt ccagagactt cttcagtcct gcaccttgac cacagtgctg actctcctgt
241 gagcagtctt cccacagcag aggacaccta tagggtgagc ttggccaaag gtgtctcgat
301 gtctctgcct tcctcacctt tgctgcctcg acagtctcac ttggtgcaat caagagtgaa
361 caaaaaatcc ccaggtcccg tcaggaagcc caagtatgtg gaaagcccca gagtgcctgg
421 agatgcagtt ataatgccat tcagagaagt agccaagcca acagagcctg atgagcatgc
481 aaaggccgat aatgaaccga gctgttcgcc ggcagctcaa gaactgttga caaggctggg
541 atttttactg ggagaaggga tcccaagtgc cacacacata accattgaag acaaaaatga
601 aaccatgtgc acagctctga gtcaaggcat cagtccttgc tccacactaa caagcagcac
661 cgcatctcct agcaccgata gcccctgctc aaccttgaat agctgtgtca gcaagacggc
721 agccaacaaa agtccctgtg agaccattag cagccctagt tccaccctgg aaagcaagga
781 cagtggaatt atagccacaa ttacaagttc atccgaaaat gatgaccgga gtggctccag
841 tttggaatgg aataaagatg gaagcctaag attaggggtt cagaagggag tgcttcatga
901 ccgcagggca gataactgct ccccagtggc agaagaggag accaccgggt cagcagagag
961 cacgctgccc aaagcagaat cctcagctgg agatggtcca gtcccttatt ctcagggctc
1021 cagctcacta ataatgccac ggcccaactc agttgcagca acaagctcaa ccaaattgga
1081 agatctgagt tatttagacg ggcagagaaa tgctcctcta cggacgtcaa ttagattacc
1141 atggcacaat acggccggag cacgatttgc tccctacaag ccacaagaca ttttgttgaa
1201 acccttgttg tttgaagtac caagcataac aacagactct gtgtttgtgg gaagggattg
1261 gctctttcac cagatagaag aaaacttgag gaacacagaa ctggcagaaa acagaggcgc
1321 ggtggtggtt ggcaatgtgg gatttgggaa gacggcaatc atttccaagt tggtggccct
1381 gagctgccac ggaagccgca tgaggcagat tgcttccaac agcccgggtt catcacctaa
1441 aacctctgac cccactcagg atcttcattt cactccgttg ctttcaccga gttcttccac
1501 aagtgcttcc agcacagcta aaacacctct tgggtctatc agtgctgaaa accagagacc
1561 aagagaggat gcagtgaaat atcttgcttc taaggtggtg gcctaccact actgccaggc
1621 tgacaacacg tacacttgcc tggtgcccga gtttgtgcac agcatcgcag ctttgctctg
1681 ccggtcccat cagctggccg cctacagaga ccttctgata aaggagcccc aactacagag
1741 catgctgagc ctccgatcct gtgtgcagga cccggtggca gctttcaaga ggggagtgct
1801 ggagccactc acaaacctga gaaatgagca gaaaattcct gaagaagaat acattatttt
1861 gatagatggc ttaaatgaag ctgagtttca taaacctgat tatggagata cgctttcttc
1921 atttattacc aaaattattt ctaaatttcc tgcctggttg aagttgattg tgactgtaag
1981 agcaaatttt caggaaatca taagtgcgct gccatttgtc aagctttcct tagatgactt
2041 cccagacaac aaagacatcc acagtgacct gcacgcctac gtccagcaca gggtgcacag
2101 cagccaggac atcctcagca atatctccct gaacggcaag gccgatgcca cactcattgg
2161 aaaagtgagc agccacctgg tgctgcggag cctcggctcc tacctgtacc tcaagctcac
2221 cctggacctt ttccagaggg gccacttggt cattaagagt gccagctaca aggtggtgcc
2281 cgtgtctctc tctgagctct atttgcttca gtgcaacatg aagttcatga cccagtccgc
2341 ctttgagagg gcacttccga ttctcaacgt ggccctcgca tccctccacc ccatgacaga
2401 cgagcagatc tttcaggcta ttaatgctgg ccacatccag ggggagcagg gatgggaaga
2461 ctttcagcag aggatggacg ccctctcctg cttcctcatt aagaggcgag acaaaacccg
2521 catgttctgc cacccgtcct tcagggagtg gcttgtatgg agagcagacg gggaaaacac
2581 ggccttcctg tgtgagccca ggaacgggca cgcgctcttg gcattcatgt tctcgcgtca
2641 ggagggcaag ttgaaccgcc agcagaccat ggagcttggc caccacatcc tgaaggcgca
2701 cattttcaag ggcctcagta agaagacggg aatttcttca agccatctcc aagccctgtg
2761 gatcggctac agcaccgagg ggctgtccgc cgccctggcc tctctcagga atctctatac
2821 tcccaacgtg aaggtgagcc gtctcctgat tttgggaggg gccaacgtga actacaggac
2881 agaagtgtta aataatgccc caatcctgtg cgtccagtct caccttggcc acgaggaagt
2941 tgtcactctg ctcctggaat ttggtgcctg cctggacgga acgtcagaga acggcatgac
3001 tgccctctgt tacgcagcag ctgctggcca catgaagctg gtgtgtctgc tgaccaagaa
3061 gggagtgaga gtggaccact tggataagaa gggccagtgt gcgcttgtcc acagtgccct
3121 acggggccac ggtgacattc tccagtacct gctgacttgt gagtggtcgc cgggtcctcc
3181 ccagccaggc accctgagga agagccacgc cctgcagcag gcgctgaccg cggcggccag
3241 catgggccac agctcggtgg tccagtgctt gctggggatg gagaaggaac atgaagtaga
3301 agtcaatggc accgacacat tgtggggaga aacagccctg actgccgccg caggaagagg
3361 gaagctggag gtctgtgagc tgctgctggg gcatggagct gctgtgtcgc ggacaaacag
3421 gagaggggtt ccacctttgt tttgtgcagc acgccagggg cattggcaga ttgttagact
3481 gctgttggaa cgcggctgtg atgtgaacct aagtgacaag caaggccgga cgcccctcat
3541 ggtggctgct tgtgaagggc acttgagcac cgtggaattc ctcctttcaa aaggtgcagc
3601 cctttcttct ctagacaaag agggtctgtc agcattaagc tgggcttgtc tgaaaggtca
3661 cagggcagtg gtccagtatc tggttgaaga aggagctgca atagaccaga cagacaagaa
3721 tggccgcaca cccttggacc tggctgcctt ctatggcgat gccgagactg tgctgtacct
3781 ggtggagaag ggagccgtga tcgagcatgt ggaccacagc gggatgcggc ccttggacag
3841 agccatcggc tgccggaaca catctgtagt ggtggcgcta ctcagaaagg gagccaagtt
3901 aggaaatgct gcttgggcga tggccacttc caaacctgat atcttgatta tacttttaca
3961 gaaattaatg gaggaaggaa atgtgatgta caaaaaaggg aaaatgaaag aggcagccca
4021 gaggtaccag tatgccttaa gaaagtttcc tcgagaagga ttcggagagg acatgagacc
4081 cttcaatgaa ttaagggttt ccctctatct caatttgtcg cgatgccgaa gaaaaacaaa
4141 tgactttggc atggcagagg aatttgcttc caaggctctc gaattgaagc ccaagtccta
4201 tgaagccttt tatgccagag caagagcgaa gagaaatagc aggtaccgca attcgtggca
4261 gctctggctg acctgcaaga ggctgtgaaa ctctgtccca ccaatcagga agtcaagagg
4321 cttctggccc gcgtagaaga ggagtgcaaa caactccaga ggagtcaaca gcaaaaacag
4381 cagggcccgc taccagctcc actcaacgac tccgagaacg aagaggacac cccaacccct
4441 ggcttaagtg accactttca ctctgaggag actgaagagg aagaaacttc tccccaggaa
4501 gaatctgttt ccccaactcc caggtcccag ccatcctcat ctgtcccttc ctcatacatc
4561 cgaaaccttc aagaagggtt acagtccaaa ggaaggccgg tatcgccaca gagcagggca
4621 ggaatcggca agtccctgag agagcctgtg gcccagccag ggctgctcct gcagccctcc
4681 aagcaggccc agatcgtgaa aaccagccag cacctgggct ctggccagtc ggcagtgaga
4741 aatggcagta tgaaagttca gatctcttct cagaaccctc ctccaagtcc catgccaggg
4801 agaatcgctg ccactcctgc tgggagcaga acccagcatt tagagggaac aggtactttc
4861 actacaagag ctggttgtgg ccactttggg gatcggctgg gccccagcca gaatgtccgc
4921 ctgcagtgtg gtgagaatgg ccctgcacac cctttaccaa gtaagacgaa aaccacagag
4981 aggcttctgt ctcattcctc cgtggctgtg gacgcagccc ctccaaacca aggtgggctg
5041 gcgacctgca gcgacgtgcg acacccagct tccctcacca gctcaggctc ttctggttct
5101 ccatccagca gcataaagat gtcaagttca accagtagtt tgacttcgag cagcagtttt
5161 tcagatggct tcaaggtcca aggaccagat actagaatta aagacaaggt tgtaacccac
5221 gttcagagcg gtacagctga gcacagaccc cgcaacacgc cgttcatggg catcatggat
5281 aagactgcga ggttccaaca gcagagcaat cctccaagcc gcagctggca ctgtccggca
5341 ccagaggggc tgctgacaaa cacgtcttct gcagctggcc tgcagtctgc taacactgag
5401 aagccctctc tcatgcaagt gggaggatat aataaccaag ccaaaacctg ttctgtttct
5461 accctgagtg caagtgtcca caatggggca caagtgaagg agctagaaga aagcaagtgc
5521 caaattccag tccactctca agagaacagg ataactaaga ctgtttctca tctgtaccag
5581 gaacgtctct ccaaacagca gcctcatatt agtaatgaag cccacaggag ccacctcact
5641 gcagccaaac caaagcgatc atttatagag tcaaatgtgt gaaccttaag aaagccccat
5701 ttgtggaatt tggaaacgtg tgttgactcc tggtggtaaa ttaaatagtt tttttcatca
5761 gaaaaattat tttttagcca ttttttttct ttggggtgga tctgatgcca ttgatatatc
5821 taaaatgtgg gataaaactt ctttaatagc tagaaatcac cataaataag aatgctaaac
5881 agaattgaaa attatatcaa cttaaaattt taagacagcc cagaagacat taatgactct
5941 cacttatgaa attgtttggc ttttgccact ttcctccttg cctttgctat atggtagaat
6001 cacagaactt acttagagaa taaatatgtc tattgttcaa gagtaacagg tttaactcat
6061 gaccaagtga tgtacatcca agtgatgtat tctggaaacg atggaatttt acagttacag
6121 ttccattgag tcaaatccca ttttatatat acataaaaat taagttctga gtgagttcta
6181 gctaaatata agtgcgactg taaacgcagc c
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