LOCUS BC150297 5178 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens phosphoinositide-3-kinase, catalytic, delta
polypeptide, mRNA (cDNA clone MGC:167031 IMAGE:8860364), complete
cds.
ACCESSION BC150297
VERSION BC150297.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5178)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5178)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: RIKEN
cDNA Library Preparation: RIKEN
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 12 Row: c Column: 8.
FEATURES Location/Qualifiers
source 1..5178
/db_xref="H-InvDB:HIT000435793"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:167031 IMAGE:8860364"
/tissue_type="Clones donated by RIKEN"
/clone_lib="NIH_MGC_424"
/lab_host="DH10B"
/note="Vector: pFLC1"
gene 1..5178
/gene="PIK3CD"
/gene_synonym="p110D"
/db_xref="GeneID:5293"
/db_xref="HGNC:HGNC:8977"
/db_xref="MIM:602839"
CDS 156..3290
/gene="PIK3CD"
/gene_synonym="p110D"
/codon_start=1
/product="phosphoinositide-3-kinase, catalytic, delta
polypeptide"
/protein_id="AAI50298.1"
/db_xref="GeneID:5293"
/db_xref="HGNC:HGNC:8977"
/db_xref="MIM:602839"
/translation="MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLST
IKQLLWHRAQYEPLFHMLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLV
AREGDRVKKLINSQISLLIGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWE
AWLQYSFPLQLEPSAQTWGPGTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMA
CALRKKATVFRQPLVEQPEDYTLQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTM
VHSSSILAMRDEQSNPAPQVQKPRAKPPPIPAKKPCSVSLWSLEQPFRIELIQGSKVN
ADERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCF
ALYAVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKG
ELLNPTGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKILELGRHSECVHVTEEEQ
LQLREILERRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLY
LLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESY
LDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVL
MKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTL
LAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMD
VLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALL
NWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGH
FLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGL
LFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTK
VNWLAHNVSKDNRQ"
BASE COUNT 1113 a 1506 c 1475 g 1084 t
ORIGIN
1 ggcagctgcg ccgggacgat aaggagtcag gccagggcgg gatgacactc attgattcta
61 aagcatcttt aatctgccag gcggaggggg ctttgctggt ctttcttgga ctattccaga
121 gaggacaact gtcatctggg aagtaacaac gcaggatgcc ccctggggtg gactgcccca
181 tggaattctg gaccaaggag gagaatcaga gcgttgtggt tgacttcctg ctgcccacag
241 gggtctacct gaacttccct gtgtcccgca atgccaacct cagcaccatc aagcagctgc
301 tgtggcaccg cgcccagtat gagccgctct tccacatgct cagtggcccc gaggcctatg
361 tgttcacctg catcaaccag acagcggagc agcaagagct ggaggacgag caacggcgtc
421 tgtgtgacgt gcagcccttc ctgcccgtcc tgcgcctggt ggcccgtgag ggcgaccgcg
481 tgaagaagct catcaactca cagatcagcc tcctcatcgg caaaggcctc cacgagtttg
541 actccttgtg cgacccagaa gtgaacgact ttcgcgccaa gatgtgccaa ttctgcgagg
601 aggcggccgc ccgccggcag cagctgggct gggaggcctg gctgcagtac agtttccccc
661 tgcagctgga gccctcggct caaacctggg ggcctggtac cctgcggctc ccgaaccggg
721 cccttctggt caacgttaag tttgagggca gcgaggagag cttcaccttc caggtgtcca
781 ccaaggacgt gccgctggcg ctgatggcct gtgccctgcg gaagaaggcc acagtgttcc
841 ggcagccgct ggtggagcag ccggaagact acacgctgca ggtgaacggc aggcatgagt
901 acctgtatgg cagctacccg ctctgccagt tccagtacat ctgcagctgc ctgcacagtg
961 ggttgacccc tcacctgacc atggtccatt cctcctccat cctcgccatg cgggatgagc
1021 agagcaaccc tgccccccag gtccagaaac cgcgtgccaa accacctccc attcctgcga
1081 agaagccttg ctctgtgtcc ctgtggtccc tggagcagcc gttccgcatc gagctcatcc
1141 agggcagcaa agtgaacgcc gacgagcgga tgaagctggt ggtgcaggcc gggcttttcc
1201 acggcaacga gatgctgtgc aagacggtgt ccagctcgga ggtgagcgtg tgctcggagc
1261 ccgtgtggaa gcagcggctg gagttcgaca tcaacatctg cgacctgccc cgcatggccc
1321 gtctctgctt tgcgctgtac gccgtgatcg agaaagccaa gaaggctcgc tccaccaaga
1381 agaagtccaa gaaggcggac tgccccattg cctgggccaa cctcatgctg tttgactaca
1441 aggaccagct taagaccggg gaacgctgcc tctacatgtg gccctccgtc ccagatgaga
1501 agggcgagct gctgaacccc acgggcactg tgcgcagtaa ccccaacacg gatagcgccg
1561 ctgccctgct catctgcctg cccgaggtgg ccccgcaccc cgtgtactac cccgccctgg
1621 agaagatctt ggagctgggg cgacacagcg agtgtgtgca tgtcaccgag gaggagcagc
1681 tgcagctgcg ggaaatcctg gagcggcggg ggtctgggga gctgtatgag cacgagaagg
1741 acctggtgtg gaagctgcgg catgaagtcc aggagcactt cccggaggcg ctagcccggc
1801 tgctgctggt caccaagtgg aacaagcatg aggatgtggc ccagatgctc tacctgctgt
1861 gctcctggcc ggagctgccc gtcctgagcg ccctggagct gctagacttc agcttccccg
1921 attgccacgt aggctccttc gccatcaagt cgctgcggaa actgacggac gatgagctgt
1981 tccagtacct gctgcagctg gtgcaggtgc tcaagtacga gtcctacctg gactgcgagc
2041 tgaccaaatt cctgctggac cgggccctgg ccaaccgcaa gatcggccac ttccttttct
2101 ggcacctccg ctccgagatg cacgtgccgt cggtggccct gcgcttcggc ctcatcctgg
2161 aggcctactg caggggcagc acccaccaca tgaaggtgct gatgaagcag ggggaagcac
2221 tgagcaaact gaaggccctg aatgacttcg tcaagctgag ctctcagaag acccccaagc
2281 cccagaccaa ggagctgatg cacttgtgca tgcggcagga ggcctaccta gaggccctct
2341 cccacctgca gtccccactc gaccccagca ccctgctggc tgaagtctgc gtggagcagt
2401 gcaccttcat ggactccaag atgaagcccc tgtggatcat gtacagcaac gaggaggcag
2461 gcagcggcgg cagcgtgggc atcatcttta agaacgggga tgacctccgg caggacatgc
2521 tgaccctgca gatgatccag ctcatggacg tcctgtggaa gcaggagggg ctggacctga
2581 ggatgacccc ctatggctgc ctccccaccg gggaccgcac aggcctcatt gaggtggtac
2641 tccgttcaga caccatcgcc aacatccaac tcaacaagag caacatggca gccacagccg
2701 ccttcaacaa ggatgccctg ctcaactggc tgaagtccaa gaacccgggg gaggccctgg
2761 atcgagccat tgaggagttc accctctcct gtgctggcta ttgtgtggcc acatatgtgc
2821 tgggcattgg cgatcggcac agcgacaaca tcatgatccg agagagtggg cagctgttcc
2881 acattgattt tggccacttt ctggggaatt tcaagaccaa gtttggaatc aaccgcgagc
2941 gtgtcccatt catcctcacc tacgactttg tccatgtgat tcagcagggg aagactaata
3001 atagtgagaa atttgaacgg ttccggggct actgtgaaag ggcctacacc atcctgcggc
3061 gccacgggct tctcttcctc cacctctttg ccctgatgcg ggcggcaggc ctgcctgagc
3121 tcagctgctc caaagacatc cagtatctca aggactccct ggcactgggg aaaacagagg
3181 aggaggcact gaagcacttc cgagtgaagt ttaacgaagc cctccgtgag agctggaaaa
3241 ccaaagtgaa ctggctggcc cacaacgtgt ccaaagacaa caggcagtag tggctcctcc
3301 cagccctggg cccaagagga ggcggctgcg ggtcgtgggg accaagcaca ttggtcctaa
3361 aggggctgaa gagcctgaac tgcacctaac gggaaagaac cgacatggct gccttttgtt
3421 tacactggtt atttatttat gacttgaaat agtttaagga gctaaacagc cataaacgga
3481 aacgcctcct tcatgcagcg gcggtgctgg gccccccgag gctgcacctg gctctcggct
3541 gaggattgtc accccaagtc ttccagctgg tggatctggg cccagcaaag actgttctcc
3601 tcccgaggga accttcttcc caggcctccc gccagactgc ctgggtcctg gcgcctggcg
3661 gtcacctggt gcctactgtc cgacaggatg cctcgatcct cgtgcgaccc accctgtgta
3721 tcctccctag actgagttct ggcagctccc cgaggcagcc ggggtaccct ctagattcag
3781 ggatgcttgc tctccacttt tcaagtgggt cttgggtacg agaattccct catctttctc
3841 tactgtaaag tgattttgtt tgcaggtaag aaaataatag atgactcacc acacctctac
3901 ggctggggag atcaggccca gccccataaa ggagaatcta cgctggtcct caggacgtgt
3961 taaagagatc tgggcctcat gtagctcacc ccggtcacgc atgaaggcaa aagcaggtca
4021 gaagctaata ctctgccatt atctcaaaaa tctttttttt tttttttgag atggggtctt
4081 cctctgttgc ccaggctgga gtgcagtggt gcaatcttgg ctcactgtaa cctccgcctc
4141 ccaggttcaa gtgattcttc tgcctcagcc tcctgagtag ctgggattac aggtgtgcac
4201 caccgtaccc agctaatttt tgtattttag tagagacggg ggtttcacca tgttggctgg
4261 gctggtctcg aactcctgac ctcaggtgat ccacccgcct gagcctccca aagtgctggg
4321 attacaggca tgagccaccg cgcccggccc actctgccat tgtctaagcc acctctgaaa
4381 gcaggtttta acaaaaggat gaggccagaa ctcttccaga accatcacct ttgggaacct
4441 gctgtgagag tgctgaggta ccagaagtgt gagaacgagg gggcgtgctg ggatctttct
4501 ctctgactat acttagtttg aaatggtgca ggcttagtct taagcctcca aaggcctgga
4561 tttgagcagc tttagaaatg caggttctag ggcttctccc agccttcaga agccaactaa
4621 ctctgcagat ggggctagga ctgtgggctt ttagcagccc acaggtgatc ctaacatatc
4681 aggccatgga ctcaggacct gcccggtgat gctgttgatt tctcaaaggt cttccaaaac
4741 tcaacagagc cagaagtagc cgcccgctca gcggctcagg tgccagctct gttctgattc
4801 accaggggtc cgtcagtagt cattgccacc cgcggggcac ctccctggcc acacgcctgt
4861 tcccagcaag tgctgaaact cactagaccg tctgcctgtt tcgaaatggg gaaagccgtg
4921 cgtgcgcgtt atttatttaa gtgcgcctgt gtgcgcgggt gtgggagcac actttgcaaa
4981 gccacagcgt ttctggtttt gggtgtacag tcttgtgtgc ctggcgagaa gaatattttc
5041 tattttttta agtcatttca tgtttctgtc tggggaaggc aagttagtta agtatcactg
5101 atgtgggttg agaccagcac tctgtgaaac cttgaaatga gaagtaaagg cagatgaaaa
5161 ggaaaaaaaa aaaaaaaa
//