LOCUS BC150257 7700 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens glucocorticoid receptor DNA binding factor 1, mRNA
(cDNA clone MGC:166817 IMAGE:9007187), complete cds.
ACCESSION BC150257
VERSION BC150257.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7700)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 7700)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 9 Row: a Column: 2.
FEATURES Location/Qualifiers
source 1..7700
/db_xref="H-InvDB:HIT000435753"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:166817 IMAGE:9007187"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+"
gene 1..7700
/gene="GRLF1"
/gene_synonym="GRF-1"
/gene_synonym="P190-A"
/gene_synonym="P190A"
/gene_synonym="p190RhoGAP"
/db_xref="GeneID:2909"
/db_xref="HGNC:HGNC:4591"
/db_xref="MIM:605277"
CDS 9..4508
/gene="GRLF1"
/gene_synonym="GRF-1"
/gene_synonym="P190-A"
/gene_synonym="P190A"
/gene_synonym="p190RhoGAP"
/codon_start=1
/product="GRLF1 protein"
/protein_id="AAI50258.1"
/db_xref="GeneID:2909"
/db_xref="HGNC:HGNC:4591"
/db_xref="MIM:605277"
/translation="MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVR
PSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDD
QTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGF
LLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFAL
SKKNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDK
YEWLVSRIVKNHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIE
RRRKLYLAALPLAFEALIPNLDEIDHLSCIKAKKLLETKPEFLKWFVVLEETPWDATS
HIDNMENERIPFDLMDTVPAEQLYEAHLEKLRNERKRVEMRRAFKENLETSPFITPGK
PWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDKAKEEFQELLLEYSELFYELEL
DAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACV
DAKIEHLISSRFIRPSDRNQKNSLSDPNIDRINLVILGKDGLARELANEIRALCTNDD
KYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSR
ESTLGRRDNHLVHLPLTLILVNKRGDTSGETLHSLIQQGQQIASKLQCVFLDPASAGI
GYGRNINEKQISQVLKGLLDSKRNLNLVSSTASIKDLADVDLRIVMCLMCGDPFSADD
ILFPVLQSQTCKSSHCGSNNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYI
VFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDGAVDVLDNDLSREQLTEGEEIAQE
IDGRFTSIPCSQPQHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEACSTTEEVFNSPR
AGSPLCNSNLQDSEEDIEPSYSLFREDTSLPSLSKDHSKLSMELEGNDGLSFIMSNFE
SKLNNKVPPPVKPKPPVHFEITKGDLSYLDQGHRDGQRKSVSSSPWLPQDGFDPSDYA
EPMDAVVKPRNEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDTSSLERG
RKVSIVSKPVLYRTRCTRLGRFASYRTSFSVGSDDELGPIRKKEEDQASQGYKGDNAV
IPYETDEDPRRRNILRSLRRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTPEKPIP
IFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGA
MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISH
LNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFF
YNRPITEPPGARPSSPSAVASTVPFLTSTPVTSQPSPPQSPPPTPQSPMQPLLPSQLQ
AEHTL"
BASE COUNT 1911 a 2018 c 2060 g 1711 t
ORIGIN
1 ccacgcgtat gatgatggca agaaagcaag atgtccgaat tcccacctac aacatcagtg
61 tggtgggatt atctgggacc gagaaggaaa agggccagtg tgggattgga aagtcttgtt
121 tgtgcaaccg cttcgtgcgc ccgagtgctg acgagtttca cttggaccat acctccgtcc
181 tcagcaccag tgactttgga gggcgagtgg tcaataatga ccactttctc tactggggag
241 aagttagccg ctccctggag gattgtgtgg aatgtaagat gcacattgtg gagcagactg
301 aatttattga tgatcagact tttcaacctc atcgaagcac ggccctgcag ccctatatca
361 agagagctgc tgcgaccaag cttgcatcag ctgaaaaact catgtacttt tgcactgacc
421 agctggggct ggagcaggac tttgagcaga aacaaatgcc agacggaaag ctgctggttg
481 atggttttct tcttggtatt gatgttagca ggggcatgaa taggaacttt gatgaccagc
541 tcaagtttgt ctccaatctc tacaatcagc ttgcaaaaac aaaaaagccc atagtggtgg
601 tcctgactaa gtgtgacgaa ggtgttgagc ggtacattag agatgcacat acttttgcct
661 taagcaaaaa gaacctccag gttgtggaga cctcagcgag atccaatgta aacgtggact
721 tggctttcag caccttagtg caactcattg ataaaagtcg gggaaagaca aaaatcattc
781 cttattttga agctctcaag cagcagagtc agcagatagc tacagcaaaa gacaagtatg
841 agtggctggt gagtcgcatt gtgaaaaacc acaatgagaa ctggctgagt gtcagccgaa
901 agatgcaggc ctctccagaa taccaggact atgtctacct ggaagggact cagaaagcca
961 agaagctgtt tctacagcac atccaccgcc tcaagcatga gcatatcgag cgtaggagaa
1021 agctgtacct ggcagccctg ccattagctt ttgaagctct tatacctaat ctagatgaaa
1081 tagaccacct aagctgcata aaagccaaaa agctcttaga aaccaagcca gaattcttga
1141 agtggtttgt tgtgcttgaa gagaccccat gggatgccac cagtcacatt gacaacatgg
1201 aaaacgaacg gattcccttt gatttaatgg ataccgtccc tgcagagcag ctatacgagg
1261 cccacttaga gaagctgagg aacgaaagga aaagagttga gatgcgaagg gcgtttaaag
1321 aaaacctgga gacttctcct ttcataactc ccggaaagcc ttgggaagag gcccgtagtt
1381 ttattatgaa tgaggatttc taccagtggc tggaggaatc tgtatacatg gatatttatg
1441 gcaaacacca aaagcaaatt atagataaag caaaggaaga atttcaggag ttgcttttgg
1501 aatattcaga attgttttat gaactggagc tggatgctaa gcccagcaag gagaagatgg
1561 gtgttattca ggatgttctg ggagaggaac agcgatttaa agcattacaa aagctccaag
1621 cagagcgtga tgcccttatt ctgaaacaca ttcattttgt gtaccaccca acaaaggaga
1681 catgccccag ctgcccagct tgtgtggacg ctaagattga gcacttgatt agttctcggt
1741 ttatccggcc gtctgaccgg aatcagaaaa attcactctc tgaccctaac attgatagaa
1801 tcaacttggt tatattgggc aaagacggcc ttgcccgaga gttggccaat gagattcgag
1861 ctctttgtac aaatgatgac aagtatgtga tagatggtaa aatgtatgag ctttccctga
1921 ggccaataga ggggaatgtc aggcttcctg tgaactcttt ccagacgcca acatttcagc
1981 cccacggctg tctctgcctt tacaattcaa aggaatcgct atcctatgta gtggaaagta
2041 tagagaagag tagagagtcc acgctgggcc ggcgggataa tcatttagtc catctccccc
2101 ttacattaat tttggttaac aagagaggag acaccagtgg agagactctg catagcttaa
2161 tacagcaagg tcaacaaatt gctagcaaac ttcagtgtgt ctttctcgac cctgcttctg
2221 ctggcattgg ttacggacgc aacattaatg aaaagcaaat cagtcaagtt ttgaagggac
2281 tcctggactc taagcgtaac ttaaacctgg tcagttctac tgctagcatc aaagatttgg
2341 ctgatgttga tctgcgaatt gttatgtgtc tgatgtgtgg agatcctttt agtgcagatg
2401 acatactttt tcctgtcctt cagtcccaaa cctgtaaatc ttcccattgt ggaagcaaca
2461 actctgtttt acttgaacta ccaatcggac tgcacaagaa gcggattgaa ctgtctgttc
2521 tttcatacca ttcctccttt agcatcagaa agagccggtt ggttcatggg tacattgttt
2581 tttattcagc caaacgtaag gcctctttgg ctatgttacg tgcctttctt tgtgaagtgc
2641 aggatattat ccctattcag cttgtagcac tcactgatgg cgctgtagat gtcctggaca
2701 atgacttaag tagggaacag ctaactgagg gggaggagat tgctcaagaa attgacggaa
2761 ggttcacaag catcccctgt agccaacccc agcataaact tgagatcttt cacccatttt
2821 ttaaagatgt ggtggaaaaa aagaacataa tcgaggctac tcatatgtac gataatgctg
2881 ccgaggcctg tagcaccacc gaagaggtgt ttaactcccc ccgggcagga tcaccgctct
2941 gcaactcaaa cctgcaggat tcagaagaag atatcgagcc atcttacagc ctgtttcgag
3001 aagacacatc actgccttct ctgtccaaag accattctaa gctctctatg gaactggagg
3061 gaaatgatgg gctgtctttc attatgagca attttgagag taaactgaac aacaaagtac
3121 ctccgccagt caaaccaaag cctcctgtcc attttgaaat tacaaagggg gatctatctt
3181 atttagacca aggccatagg gatggacaga ggaagtctgt gtcttctagc ccctggctgc
3241 ctcaggatgg gtttgatcct tctgactatg ctgaacccat ggatgctgtg gtgaagccaa
3301 ggaatgaaga agaaaacata tactccgtgc cccatgacag cacccaaggc aaaatcatca
3361 ccattcggaa tatcaacaaa gcccagtcca acggcagcgg gaatggttct gacagtgaaa
3421 tggacaccag ctctctagag cgagggcgca aggtttccat cgtgagcaag ccagtgctgt
3481 acaggacgag atgcacccgg ctggggcggt ttgctagtta ccggaccagc ttcagcgtgg
3541 ggagtgatga tgagctgggg cccatccgga agaaagagga ggatcaggca tcccagggtt
3601 ataaagggga caatgctgtc attccatacg aaacagacga agacccgcgg aggaggaata
3661 ttcttcgcag cctaaggagg aacactaaga aaccaaagcc caaaccccgg ccatccatca
3721 caaaggcaac ctgggagagt aactattttg gggtgccctt aacaactgtc gtgactccag
3781 agaagccgat ccccattttt attgaaagat gtattgagta cattgaagcc acaggactga
3841 gcacggaagg catctaccgg gtcagcggga acaagtctga gatggagagt ctgcagagac
3901 agtttgatca agaccacaac ctggacctgg cagagaaaga ctttacggtg aataccgtgg
3961 ctggtgccat gaagagcttt ttctcagaac tgcctgaccc cctggtcccg tataacatgc
4021 agatcgactt ggtggaagca cacaaaatca acgaccggga gcagaagttg catgccctta
4081 aggaggtatt aaagaaattt ccaaaggaaa accacgaagt cttcaagtat gtcatctctc
4141 acctaaacaa ggtcagccac aacaacaagg tgaatctcat gaccagcgag aacctctcca
4201 tctgcttctg gcccaccttg atgagacctg atttcagcac tatggacgcc ctcacagcca
4261 cgcgcaccta ccagacaatc attgaactct ttatccagca gtgccccttc ttcttctaca
4321 atcggcccat caccgagccc cccggcgcca ggcccagctc cccctctgcc gtggcttcca
4381 ccgtcccctt cctcacttcc acgcctgtca caagtcagcc gtcgccccca cagtcgcctc
4441 cacccacccc ccagtcccca atgcagccac tgcttccctc ccagcttcaa gccgaacaca
4501 cgctgtgagc caccaagacc tggggcgaca ggagaaccgg tcctctctct gacggggtgg
4561 catttggcct tgaacaaaac caagtccact ggggacagag gcaggggcaa gtggctctcc
4621 ccattacctt ctcaagacct cagtgggagc accagccaat ggtaccatcg gctgggctgc
4681 caggtaccct gggcctggcg ctgcagacct gagctggctt ggacccattt gaggactgaa
4741 ctaggcaggc aatggctcca gtgccctccc tctgttccct ggaccaccac cccacgtagc
4801 tgctcacacc agcctccggg tgcctccctc tgcttgtaca gagcccatgg tcgggacagt
4861 gccctggcct ttgccgggga ggaggatgct ctgagattca gggtggggct ggcaacccct
4921 gaagagaaca cttcctgttg gtctgtctct tcccaccttc catctgcaca cacccccaag
4981 gtaagggtac agcccggctg gcggcctcct tgggaacgtg taggccacgg ctctgccacc
5041 actaggtacc tgctgagggc gctggctctg cagatcagaa caacggagga tagctttgtg
5101 cctggaccca gagagtgtgg gactccccgc ttcatcccca ccgtcccact ccacagcctt
5161 cccgaaacat tccctggcaa acaaaggaac actaggagaa aaaatggaaa aacccttcca
5221 gtaattaaaa aggaagaaac cacagaaaga aaactacaga cctcaagatt ccactctgtg
5281 cccgcctctg ccgggaggga gggaggcaca caggtggagc tgaccctcgt ctttgtggca
5341 gcaaaaccag gatgcctgga gctgtggcct gagggcctgc tggggtccca ctcacccact
5401 taggtctagt cgctagatcc cccgttttcc caagaagagg gttcgagccc ttggtgggga
5461 cagctgggga gatggcagtg caggctggaa cctgggctgc cccagaacac agtccattac
5521 gatagaaaca ctaggcaccc cccaggcgag agctagtggg gtgcagaggg ccccatgcca
5581 gacagccctt ggggctcgtt gcactttaag aaataggatc tgtggtgtat tccagggggc
5641 ctgatggaca cctttcccgg gcgtctgcag ctgccctgcc cgtgcccgcc tgcagtggtt
5701 ggagacggga gtggcccttc ggctcccgag ctccctctgg ggacggctgg ctcactgtct
5761 ccagttctca atggccaacg aaggtgcttg gaaacaccta accttgcaag ttttaccgcc
5821 ttttgaggaa cacaaatcgg agaacaaacc cagggttcag gcgtgttttc tgtgaatgtt
5881 ggatgatgaa tttttgtctc ttctggtgga gctgtgcctg gccctgtagg cccagggttg
5941 gctggaaggt gacatctgtg tttcgtttta gctgaggttg gcagaaacgt tcccaaactc
6001 ccccagccct ggaccccagc agatgaggaa acggccccat ttactgaccc cgcccccttt
6061 tcgaggttat gctcacctgg tcagctcctc acgtaattgg gggtggaggg aaagcatggt
6121 ggtgccctgg gccgtccctg tgtgaacgca ggcaaaagca gcccagtccc cctcactgct
6181 tgagctaaca ctgccacctc ttttgtgtga gcacaaaagc cacgtcccaa gccacctggc
6241 ccgattccac agatgtatgt gcggccagtg acttccccag gagtgtggag ggggtggtga
6301 ggaggagcac ctgggctctc tacccctctc ctcacagaag tacctgaaac taggtctggg
6361 gcactcccaa tgcagcgcct tgtcagccaa ggtgggcagg cagggactgt ggcagcttat
6421 gtccaaaggg agcccccatg cacaggaagc cacagggttc ctcttgtttc ccccgctaac
6481 ttcagcctct catctgctgc tccgggctga gggactagag gacatctcgg tcgtttgagg
6541 ggcatggcca gtcgtggcag gccggccttc agcgtccggt cagggaagcg tgcagcccaa
6601 atgggcactt gcatgggagc cacagaggag cgtccctggg gattgttggg accatgctgc
6661 ccccactccc gcttttgttg gggctctaag ttctggaagg tgtgtgcaca gagggtgctc
6721 atgggactcg catgcagctc tcagcactgg gtgggagggc gttggcttgt ccagaatggg
6781 gacgtggggc agccacccct gcccagcgag agcgcagaca ccgtgtgagg ggacagcagc
6841 ccttggtgca aagccagaga ctgatcctgg ctctgacggc tgaagaggga agacccaagg
6901 ctgggtggcg tggctcgtga atccacttag aattcttggc ttgtgtcgca tactgggtgt
6961 cacggcacac atttactctg cattgtcccc gtctttccca tcgcctagcg tttggggagg
7021 aacagggaga gagcttcggg gcgtctgtct ccgtgctctc ctgcctccac cgccttggtt
7081 ttgcttcctg ctggaggcag ggcacctgct gcgacccaga ttcttctgca ggatgtgtct
7141 gtctttgtca cggtggacag agggtgacat cataggagca gctcgctggc cagaagggga
7201 tgggggcatc cctgtgcctc actcagctcc tgctgctctt agggaaagga ggcctgggtc
7261 aagccagcat ccccttggta aagacccccg caggccacca ggcattctgg acacacacac
7321 acacacacac acacacacac acaaaacttc acagcaggcc agctgcagtg acttgtcatc
7381 aagagtcacc tcagctgcgc ccccctccca tcctttccta tgagaagcca ctgctttggg
7441 ggcgccggct agaaaaagta gggtgcggtg gccaggaggg cccctgccgc gcggggggct
7501 gggtctggtt gagtcgctgc tttcccgagg gcagcgcagg gatccgggga agctgcggca
7561 gggagcgggc gccggcttcg tggctctgag gtgtaacggg ggtgggctcc ctccctcgga
7621 ggacatcgtc tgtgtccagg tcagaaagtg gcccaggaag ggggcagttt ctgtcgcggg
7681 tccggtgggg gcgcggccgc
//