LOCUS BC150206 4089 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens 5-oxoprolinase (ATP-hydrolysing), mRNA (cDNA clone
MGC:165076 IMAGE:40148883), complete cds.
ACCESSION BC150206
VERSION BC150206.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4089)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4089)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: o Column: 7.
FEATURES Location/Qualifiers
source 1..4089
/db_xref="H-InvDB:HIT000435732"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:165076 IMAGE:40148883"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..4089
/gene="OPLAH"
/gene_synonym="5-Opase"
/gene_synonym="DKFZP434H244"
/gene_synonym="OPLA"
/db_xref="GeneID:26873"
/db_xref="HGNC:HGNC:8149"
CDS 83..3949
/gene="OPLAH"
/gene_synonym="5-Opase"
/gene_synonym="DKFZP434H244"
/gene_synonym="OPLA"
/codon_start=1
/product="5-oxoprolinase (ATP-hydrolysing)"
/protein_id="AAI50207.1"
/db_xref="GeneID:26873"
/db_xref="HGNC:HGNC:8149"
/translation="MGSPEGRFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYA
DAPTEGIRRILEQEAGMLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTR
GFRDLLHIGTQARGDLFDLAVPMPEVLYEEVLEVDERVVLHRGEAGTGTPVKGRTGDL
LEVQQPVDLGALRGKLEGLLSRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSL
SSEAMPMVRIVPRGHTACADAYLTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAP
MDTFSGSSAVLSGPAGGVVGYSATTYQQEGGQPVIGFDMGGTSTDVSRYAGEFEHVFE
ASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVT
DANLVLGRLLPASFPCIFGPGENQPLSPEASRKALEAVATEVNSFLTNGPCPASPLSL
EEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTV
HIHRHSGLLSALGLALADVVHEAQEPCSLLYAPETFVQLDQRLSRLEEQCVDALQAQG
FPRSQISTESFLHLRYQGTDCALMVSAHQHPATARSPRAGDFGAAFVERYMREFGFVI
PERPVVVDDVRVRGTGRSGLRLEDAPKAQTGPPRVDKMTQCYFEGGYQETPVYLLAEL
GYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICISVGAEVPGTVGPQLDPIQLSI
FSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQE
TVQFQIQHLGADLHPGDALLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHH
ADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEALRAPGKVPNCSGTR
NLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFG
TSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEVFGNLNAPRAV
TLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNVLTSQRVVD
VILGAFGACAASQGCMNNVTLGNAHMGYYETVAGGAGAGPSWHGRSGVHSHMTNTRIT
DPEILESRYPVILRRFELRRGSGGRGRFRGGDGVTRELLFREEALLSVLTERRAFRPY
GLHGGEPGARGLNLLIRKNGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDPAPP
PGSPPQALAFPEHGSVYEYRRAQEAV"
BASE COUNT 733 a 1330 c 1338 g 688 t
ORIGIN
1 cgagcgaccg agccggagcc gagcgccagt ttttccaggg ctaccagctg aagagctcct
61 gtgggactcc agccccacca ccatgggcag ccccgagggc cgcttccact ttgccatcga
121 ccgtgggggt accttcacag acgtctttgc ccagtgccca ggggggcacg tgcgggtctt
181 aaaactgctc tcagaggacc ctgccaacta tgcggacgcg ccaaccgaag gcatccgccg
241 catcctggag caggaggccg gcatgctcct gccccgggac cagccgctgg actccagtca
301 tatcgccagc atccgcatgg gcaccacagt ggccaccaac gcactgctgg agcggaaggg
361 ggagcgggtg gcgctgctgg tgacacgtgg cttccgagac ctgctgcaca ttggcaccca
421 agcccgtggg gacctctttg acctggccgt gcccatgcct gaggtgctgt atgaagaggt
481 gctggaggtg gacgaacgcg tggtgctgca ccgtggagag gcgggcaccg ggacgcctgt
541 gaaaggccgc acgggggacc tgctggaagt gcagcagcct gtggacctgg gggccctgcg
601 tgggaagctg gaggggctgc tatctcgagg catccgcagc ctggctgtgg tgctcatgca
661 ctcgtacacg tgggcccagc atgagcagca ggtgggtgtg ctggcccggg agctgggctt
721 cacgcacgtg tcactgtcct cggaggccat gcccatggtg cgcatcgtcc ctcgggggca
781 cacggcctgt gccgacgcct acctcacgcc cgccatccag cgctacgtgc agggcttctg
841 ccgtggcttc cagggccaac tcaaggatgt gcaggtgttg ttcatgcgct ccgatggcgg
901 cctggcgccc atggacacct tcagcggctc cagtgctgtg ctctcgggcc cggccggcgg
961 cgtggtgggc tactcagcca ccacctacca gcaggagggt ggccagcctg tcatcggctt
1021 tgacatggga ggcacgtcca cggatgtgag ccgctatgct ggggaattcg agcacgtctt
1081 cgaggccagc acagctggcg tcaccctcca ggccccgcag ctggacatca acaccgtggc
1141 agcgggaggg ggttcccgcc tcttcttcag gtctggcctc tttgtggttg ggcccgagtc
1201 agcaggagcc cacccaggac ccgcctgcta ccgcaaaggg ggccctgtga cagtgacgga
1261 tgctaatctg gtcctgggtc gcctgctgcc tgcctccttc ccctgcattt ttgggccggg
1321 agagaaccaa ccactttccc ctgaggcctc ccgcaaagcc ctggaggctg tggccactga
1381 ggtcaacagc ttcctgacca acgggccctg cccggcctcc ccgctgagcc tggaggaggt
1441 ggccatgggg ttcgtgcgcg tggccaacga ggccatgtgc cggcccatcc gtgcactcac
1501 gcaggcaaga ggccatgacc cctcagccca tgtgctggcc tgctttgggg gagctggtgg
1561 gcagcatgca tgtgccatcg cccgggccct gggcatggac acggtgcaca tccacaggca
1621 cagtgggctg ctgtcggccc tggggctggc cctggctgac gtggtgcatg aggcacagga
1681 accctgctcc ctgctctacg cgcctgagac cttcgtgcag ctggaccaga ggctgagccg
1741 cctggaggag cagtgtgtgg atgctctgca ggcccagggc ttccccaggt cccagatcag
1801 cactgagagc ttcctgcacc tgcgctacca gggcacggac tgtgctctga tggtgtctgc
1861 ccaccagcac ccagccacag cccgctcgcc ccgtgcgggg gacttcgggg cagcctttgt
1921 ggagcggtac atgagggagt ttggctttgt catacctgag cggccggtgg tcgtggacga
1981 tgtgcgagtg cggggcaccg gccgcagtgg tcttcgcctc gaggatgccc ccaaagccca
2041 gaccgggcct ccccgggtgg acaagatgac ccagtgctac tttgaggggg gctaccagga
2101 gacccctgtg tacctgctgg cagagctggg ctatgggcac aagctccatg ggccctgcct
2161 catcatcgac agtaacagca ccatcctggt ggagccaggt tgccaggcag aggtgaccaa
2221 gacaggggac atctgcatct ccgtgggggc cgaagtcccc ggcacagtgg gcccccagct
2281 ggaccctatc cagctgtcca tcttctcaca ccgcttcatg agcattgctg agcagatggg
2341 ccgcatcctg cagcgcacag ccatctccac caacatcaag gagcgtctgg acttctcctg
2401 tgccctcttt gggcccgatg gggggctggt gtccaatgcc ccccacatcc ctgtgcacct
2461 gggtgccatg caggagacgg tgcagttcca gattcagcac ctgggggccg atctccaccc
2521 tggcgacgcg ctactgagca accatcccag tgccgggggc agccacctgc cagacctgac
2581 tgttatcaca ccggtgtttt ggccgggtca gacgcggcct gtgttctatg tggccagccg
2641 agggcaccac gcagacatcg ggggcatcac accaggctcc atgccccccc actccaccat
2701 gctgcaacag gagggtgccg tctttctgtc cttcaaactt gtccaggggg gcgtcttcca
2761 ggaggaggcg gtgacggagg ccctgcgggc gccaggcaag gtccccaact gcagcggaac
2821 cagaaacctg cacgacaacc tgtcggacct ccgtgcccag gtggcagcca accagaaggg
2881 catccagctg gtgggggagc tcattgggca gtacggcctg gacgtggtgc aggcctacat
2941 gggccatatt caggcaaacg ctgagctggc cgtgcgagac atgttgcgtg cctttggaac
3001 ctcccggcag gcccggggcc tgcccctgga ggtgtcctcg gaagaccaca tggacgacgg
3061 ttcccccatc cgcctccgtg tgcagatcag cctgagtcag ggcagcgctg tgtttgactt
3121 cagcggcact gggccggagg tgtttggtaa tctcaacgca ccgcgggccg taaccctgtc
3181 cgccctcatc tactgcctgc gctgtctggt gggccgcgac atcccactca accagggctg
3241 cctggcgcca gtgcgcgtgg tcattccccg aggctccatc ctggacccgt cgcccgaggc
3301 ggcggtggtg ggcggcaacg tgctcacgtc gcagcgcgtg gtggatgtca tcctgggggc
3361 ctttggggcc tgcgccgcct cccagggctg catgaacaac gtgaccctgg gcaacgccca
3421 catgggctac tacgagacgg tggcgggcgg cgcgggcgcg ggtcccagct ggcacgggcg
3481 cagcggtgtg cacagccaca tgaccaacac acgcatcacc gaccctgaga tcctggagag
3541 ccggtacccg gtcatcctgc gccgcttcga gctgcggcgg ggctcggggg gcagaggccg
3601 cttccgaggc ggcgacggcg tcacccgcga gctgctcttt cgtgaggagg cgctgctgtc
3661 agtgctgacc gagcgccgcg ccttccggcc atacgggctc cacgggggcg agcctggcgc
3721 ccgcggccta aacctgctga tccgcaaaaa cggccggacg gtgaatctgg gcggcaagac
3781 gtcggtgacc gtgtaccccg gggatgtgtt ctgtctccac acgcccggcg gcggtggcta
3841 tggggacccg gaggaccccg ccccaccgcc ggggtcgccc ccgcaagcac tggcctttcc
3901 cgagcacggc agcgtctatg agtatcgccg ggcccaggag gccgtgtgag gatcccgcaa
3961 taaagatgcc ttaagtctcc cggttctggg gacgcagcta cggcgcctaa aaaaaaaaaa
4021 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4081 aaaaaaaaa
//