LOCUS BC150182 4831 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens reticulon 4, mRNA (cDNA clone MGC:164945
IMAGE:40148210), complete cds.
ACCESSION BC150182
VERSION BC150182.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4831)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4831)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: i Column: 20.
FEATURES Location/Qualifiers
source 1..4831
/db_xref="H-InvDB:HIT000435708"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:164945 IMAGE:40148210"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..4831
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
CDS 249..3827
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/codon_start=1
/product="reticulon 4"
/protein_id="AAI50183.1"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTIS
AGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEV
SEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKL
VSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFER
VWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPST
PEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEK
NTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV
TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAV
PSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPEN
INAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSP
DSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKP
YLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRET
ETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTE
LPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKV
LVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLS
LTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELV
QKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALI
SLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
BASE COUNT 1458 a 1055 c 1075 g 1243 t
ORIGIN
1 gtccgctggc ctcactccta gctcatctgg gcggcggcgg caactgggga cagggcgggt
61 ggcgcatcac cggcgcggag gcaggaggag cagtctcatt gttccgggag ccgtcaccac
121 agtaggtccc tcggctcagt cggcccagcc cctctcagtc ctccccaacc cccacaaccg
181 cccgcggctc tgagacgcgg ccccggcggc ggcggcagca gctgcagcat catctccacc
241 ctccagccat ggaagacctg gaccagtctc ctctggtctc gtcctcggac agcccacccc
301 ggccgcagcc cgcgttcaag taccagttcg tgagggagcc cgaggacgag gaggaagaag
361 aggaggagga agaggaggac gaggacgaag acctggagga gctggaggtg ctggagagga
421 agcccgccgc cgggctgtcc gcggccccag tgcccaccgc ccctgccgcc ggcgcgcccc
481 tgatggactt cggaaatgac ttcgtgccgc cggcgccccg gggacccctg ccggccgctc
541 cccccgtcgc cccggagcgg cagccgtctt gggacccgag cccggtgtcg tcgaccgtgc
601 ccgcgccatc cccgctgtct gctgccgcag tctcgccctc caagctccct gaggacgacg
661 agcctccggc ccggcctccc cctcctcccc cggccagcgt gagcccccag gcagagcccg
721 tgtggacccc gccagccccg gctcccgccg cgcccccctc caccccggcc gcgcccaagc
781 gcaggggctc ctcgggctca gtggatgaga ccctttttgc tcttcctgct gcatctgagc
841 ctgtgatacg ctcctctgca gaaaatatgg acttgaagga gcagccaggt aacactattt
901 cggctggtca agaggatttc ccatctgtcc tgcttgaaac tgctgcttct cttccttctc
961 tgtctcctct ctcagccgct tctttcaaag aacatgaata ccttggtaat ttgtcaacag
1021 tattacccac tgaaggaaca cttcaagaaa atgtcagtga agcttctaaa gaggtctcag
1081 agaaggcaaa aactctactc atagatagag atttaacaga gttttcagaa ttagaatact
1141 cagaaatggg atcatcgttc agtgtctctc caaaagcaga atctgccgta atagtagcaa
1201 atcctaggga agaaataatc gtgaaaaata aagatgaaga agagaagtta gttagtaata
1261 acatccttca taatcaacaa gagttaccta cagctcttac taaattggtt aaagaggatg
1321 aagttgtgtc ttcagaaaaa gcaaaagaca gttttaatga aaagagagtt gcagtggaag
1381 ctcctatgag ggaggaatat gcagacttca aaccatttga gcgagtatgg gaagtgaaag
1441 atagtaagga agatagtgat atgttggctg ctggaggtaa aatcgagagc aacttggaaa
1501 gtaaagtgga taaaaaatgt tttgcagata gccttgagca aactaatcac gaaaaagata
1561 gtgagagtag taatgatgat acttctttcc ccagtacgcc agaaggtata aaggatcgtt
1621 caggagcata tatcacatgt gctcccttta acccagcagc aactgagagc attgcaacaa
1681 acatttttcc tttgttagga gatcctactt cagaaaataa gaccgatgaa aaaaaaatag
1741 aagaaaagaa ggcccaaata gtaacagaga agaatactag caccaaaaca tcaaaccctt
1801 ttcttgtagc agcacaggat tctgagacag attatgtcac aacagataat ttaacaaagg
1861 tgactgagga agtcgtggca aacatgcctg aaggcctgac tccagattta gtacaggaag
1921 catgtgaaag tgaattgaat gaagttactg gtacaaagat tgcttatgaa acaaaaatgg
1981 acttggttca aacatcagaa gttatgcaag agtcactcta tcctgcagca cagctttgcc
2041 catcatttga agagtcagaa gctactcctt caccagtttt gcctgacatt gttatggaag
2101 caccattgaa ttctgcagtt cctagtgctg gtgcttccgt gatacagccc agctcatcac
2161 cattagaagc ttcttcagtt aattatgaaa gcataaaaca tgagcctgaa aaccccccac
2221 catatgaaga ggccatgagt gtatcactaa aaaaagtatc aggaataaag gaagaaatta
2281 aagagcctga aaatattaat gcagctcttc aagaaacaga agctccttat atatctattg
2341 catgtgattt aattaaagaa acaaagcttt ctgctgaacc agctccggat ttctctgatt
2401 attcagaaat ggcaaaagtt gaacagccag tgcctgatca ttctgagcta gttgaagatt
2461 cctcacctga ttctgaacca gttgacttat ttagtgatga ttcaatacct gacgttccac
2521 aaaaacaaga tgaaactgtg atgcttgtga aagaaagtct cactgagact tcatttgagt
2581 caatgataga atatgaaaat aaggaaaaac tcagtgcttt gccacctgag ggaggaaagc
2641 catatttgga atcttttaag ctcagtttag ataacacaaa agataccctg ttacctgatg
2701 aagtttcaac attgagcaaa aaggagaaaa ttcctttgca gatggaggag ctcagtactg
2761 cagtttattc aaatgatgac ttatttattt ctaaggaagc acagataaga gaaactgaaa
2821 cgttttcaga ttcatctcca attgaaatta tagatgagtt ccctacattg atcagttcta
2881 aaactgattc attttctaaa ttagccaggg aatatactga cctagaagta tcccacaaaa
2941 gtgaaattgc taatgccccg gatggagctg ggtcattgcc ttgcacagaa ttgccccatg
3001 acctttcttt gaagaacata caacccaaag ttgaagagaa aatcagtttc tcagatgact
3061 tttctaaaaa tgggtctgct acatcaaagg tgctcttatt gcctccagat gtttctgctt
3121 tggccactca agcagagata gagagcatag ttaaacccaa agttcttgtg aaagaagctg
3181 agaaaaaact tccttccgat acagaaaaag aggacagatc accatctgct atattttcag
3241 cagagctgag taaaacttca gttgttgacc tcctgtactg gagagacatt aagaagactg
3301 gagtggtgtt tggtgccagc ctattcctgc tgctttcatt gacagtattc agcattgtga
3361 gcgtaacagc ctacattgcc ttggccctgc tctctgtgac catcagcttt aggatataca
3421 agggtgtgat ccaagctatc cagaaatcag atgaaggcca cccattcagg gcatatctgg
3481 aatctgaagt tgctatatct gaggagttgg ttcagaagta cagtaattct gctcttggtc
3541 atgtgaactg cacgataaag gaactcaggc gcctcttctt agttgatgat ttagttgatt
3601 ctctgaagtt tgcagtgttg atgtgggtat ttacctatgt tggtgccttg tttaatggtc
3661 tgacactact gattttggct ctcatttcac tcttcagtgt tcctgttatt tatgaacggc
3721 atcaggcaca gatagatcat tatctaggac ttgcaaataa gaatgttaaa gatgctatgg
3781 ctaaaatcca agcaaaaatc cctggattga agcgcaaagc tgaatgaaaa cgcccaaaat
3841 aattagtagg agttcatctt taaaggggat attcatttga ttatacgggg gagggtcagg
3901 gaagaacgaa ccttgacgtt gcagtgcagt ttcacagatc gttgttagat ctttattttt
3961 agccatgcac tgttgtgagg aaaaattacc tgtcttgact gccatgtgtt catcatctta
4021 agtattgtaa gctgctatgt atggatttaa accgtaatca tatctttttc ctatctatct
4081 gaggcactgg tggaataaaa aacctgtata ttttactttg ttgcagatag tcttgccgca
4141 tcttggcaag ttgcagagat ggtggagcta gaaaaaaaaa aaaaaaaagc ccttttcagt
4201 ttgtgcactg tgtatggtcc gtgtagattg atgcagattt tctgaaatga aatgtttgtt
4261 tagacgagat cataccggta aagcaggaat gacaaagctt gcttttctgg tatgttctag
4321 gtgtattgtg acttttactg ttatattaat tgccaatata agtaaatata gattatatat
4381 gtatagtgtt tcacaaagct tagaccttta ccttccagcc accccacagt gcttgatatt
4441 tcagagtcag tcattggtta tacatgtgta gttccaaagc acataagcta gaagaagaaa
4501 tatttctagg agcactacca tctgttttca acatgaaatg ccacacacat agaactccaa
4561 catcaatttc attgcacaga ctgactgtag ttaattttgt cacagaatct atggactgaa
4621 tctaatgctt ccaaaaatgt tgtttgtttg caaatatcaa acattgttat gcaagaaatt
4681 attaattaca aaatgaagat ttataccatt gtggtttaag ctgtactgaa ctaaatctgt
4741 ggaatgcatt gtgaactgta aaagcaaagt atcaataaag cttatagact taaaaaaaaa
4801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//