LOCUS BC150180 4957 bp mRNA linear HUM 10-JUN-2008
DEFINITION Homo sapiens tet oncogene family member 2, mRNA (cDNA clone
IMAGE:40148086), complete cds.
ACCESSION BC150180
VERSION BC150180.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4957)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4957)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: g Column: 23
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..4957
/db_xref="H-InvDB:HIT000435706"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40148086"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..4957
/gene="TET2"
/db_xref="GeneID:54790"
/db_xref="HGNC:HGNC:25941"
CDS 104..2017
/gene="TET2"
/codon_start=1
/product="TET2 protein"
/protein_id="AAI50181.1"
/db_xref="GeneID:54790"
/db_xref="HGNC:HGNC:25941"
/translation="MEQDRTNHVEGNRLSPFLIPSPPICQTERLATKLQNGSPLPERA
HPEVNGDTKWHSFKSYYGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPS
LSGLLQIKKLKQDQKANGERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAV
KDFTSFSTHNCSGPENPELQILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSV
EHTHGELLEKTLSQYYPDCVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQINS
AQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPS
PAENNIQGTTKLASGEEFCSGSSSNLQAPGGSSERYLKQNEMNGAYFKQSSVFTKDSF
SATTTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVK
IEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPM
SEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIE
LKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKT
TQPSTSHKCTKLK"
BASE COUNT 1679 a 1103 c 953 g 1222 t
ORIGIN
1 gaaaggagac ccgactgcaa ctgctggatt gctgcaaggc tgagggacga gaacgagaat
61 tcaactagag ggcagccttg tggatggccc cgaagcaagc ctgatggaac aggatagaac
121 caaccatgtt gagggcaaca gactaagtcc attcctgata ccatcacctc ccatttgcca
181 gacagaacgt ctggctacaa agctccagaa tggaagccca ctgcctgaga gagctcatcc
241 agaagtaaat ggagacacca agtggcactc tttcaaaagt tattatggaa taccctgtat
301 gaagggaagc cagaatagtc gtgtgagtcc tgactttaca caagaaagta gagggtattc
361 caagtgtttg caaaatggag gaataaaacg cacagttagt gaaccttctc tctctgggct
421 ccttcagatc aagaaattga aacaagacca aaaggctaat ggagaaagac gtaacttcgg
481 ggtaagccaa gaaagaaatc caggtgaaag cagtcaacca aatgtctccg atttgagtga
541 taagaaagaa tctgtgagtt ctgtagccca agaaaatgca gttaaagatt tcaccagttt
601 ttcaacacat aactgcagtg ggcctgaaaa tccagagctt cagattctga atgagcagga
661 ggggaaaagt gctaattacc atgacaagaa cattgtatta cttaaaaaca aggcagtgct
721 aatgcctaat ggtgctacag tttctgcctc ttccgtggaa cacacacatg gtgaactcct
781 ggaaaaaaca ctgtctcaat attatccaga ttgtgtttcc attgcggtgc agaaaaccac
841 atctcacata aatgccatta acagtcaggc tactaatgag ttgtcctgtg agatcactca
901 cccatcgcat acctcagggc agatcaattc cgcacagacc tctaactctg agctgcctcc
961 aaagccagct gcagtggtga gtgaggcctg tgatgctgat gatgctgata atgccagtaa
1021 actagctgca atgctaaata cctgttcctt tcagaaacca gaacaactac aacaacaaaa
1081 atcagttttt gagatatgcc catctcctgc agaaaataac atccagggaa ccacaaagct
1141 agcgtctggt gaagaattct gttcaggttc cagcagcaat ttgcaagctc ctggtggcag
1201 ctctgaacgg tatttaaaac aaaatgaaat gaatggtgct tacttcaagc aaagctcagt
1261 gttcactaag gattcctttt ctgccactac cacaccacca ccaccatcac aattgcttct
1321 ttctccccct cctcctcttc cacaggttcc tcagcttcct tcagaaggaa aaagcactct
1381 gaatggtgga gttttagaag aacaccacca ctaccccaac caaagtaaca caacactttt
1441 aagggaagtg aaaatagagg gtaaacctga ggcaccacct tcccagagtc ctaatccatc
1501 tacacatgta tgcagccctt ctccgatgct ttctgaaagg cctcagaata attgtgtgaa
1561 caggaatgac atacagactg cagggacaat gactgttcca ttgtgttctg agaaaacaag
1621 accaatgtca gaacacctca agcataaccc accaattttt ggtagcagtg gagagctaca
1681 ggacaactgc cagcagttga tgagaaacaa agagcaagag attctgaagg gtcgagacaa
1741 ggagcaaaca cgagatcttg tgcccccaac acagcactat ctgaaaccag gatggattga
1801 attgaaggcc cctcgttttc accaagcgga atcccatcta aaacgtaatg aggcatcact
1861 gccatcaatt cttcagtatc aacccaatct ctccaatcaa atgacctcca aacaatacac
1921 tggaaattcc aacatgcctg gggggctccc aaggcaagct tacacccaga aaacaacaca
1981 gccgagcaca agtcacaaat gtaccaagtt gaaatgaatc aagggcagtc ccaaggtaca
2041 gtggaccaac atctccagtt ccaaaaaccc tcacaccagg tgcacttctc caaaacagac
2101 catttaccaa aagctcatgt gcagtcactg tgtggcacta gatttcattt tcaacaaaga
2161 gcagattccc aaactgaaaa acttatgtcc ccagtgttga aacagcactt gaatcaacag
2221 gcttcagaga ctgagccatt ttcaaactca caccttttgc aacataagcc tcataaacag
2281 gcagcacaaa cacaaccatc ccagagttca catctccctc aaaaccagca acagcagcaa
2341 aaattacaaa taaagaataa agaggaaata ctccagactt ttcctcaccc ccaaagcaac
2401 aatgatcagc aaagagaagg atcattcttt ggccagacta aagtggaaga atgttttcat
2461 ggtgaaaatc agtattcaaa atcaagcgag ttcgagactc ataatgtcca aatgggactg
2521 gaggaagtac agaatataaa tcgtagaaat tccccttata gtcagaccat gaaatcaagt
2581 gcatgcaaaa tacaggtttc ttgttcaaac aatacacacc tagtttcaga gaataaagaa
2641 cagactacac atcctgaact ttttgcagga aacaagaccc aaaacttgca tcacatgcaa
2701 tattttccaa ataatgtgat cccaaagcaa gatcttcttc acaggtgctt tcaagaacag
2761 gagcagaagt cacaacaagc ttcagttcta cagggatata aaaatagaaa ccaagatatg
2821 tctggtcaac aagctgcgca acttgctcag caaaggtact tgatacataa ccatgcaaat
2881 gtttttcctg tgcctgacca gggaggaagt cacactcaga cccctcccca gaaggacact
2941 caaaagcatg ctgctctaag gtggcatctc ttacagaagc aagaacagca gcaaacacag
3001 caaccccaaa ctgagtcttg ccatagtcag atgcacaggc caattaaggt ggaacctgga
3061 tgcaagccac atgcctgtat gcacacagca ccaccagaaa acaaaacatg gaaaaaggta
3121 actaagcaag agaatccacc tgcaagctgt gataatgtgc agcaaaagag catcattgag
3181 accatggagc agcatctgaa gcagtttcac gccaagtcgt tatttgacca taaggctctt
3241 actctcaaat cacagaagca agtaaaagtt gaaatgtcag ggccagtcac agttttgact
3301 agacaaacca ctgctgcaga acttgatagc cacaccccag ctttagagca gcaaacaact
3361 tcttcagaaa agacaccaac caaaagaaca gctgcttctg ttctcaataa ttttatagag
3421 tcaccttcca aattactaga tactcctata aaaaatttat tggatacacc tgtcaagact
3481 caatatgatt tcccatcttg cagatgtgta gagcaaatta ttgaaaaaga tgaaggtcct
3541 ttttataccc atctaggagc aggtcctaat gtggcagcta ttagagaaat catggaagaa
3601 aggtaattaa cgcaaaggca cagggcagat taacgtttat ccttttgtat atgtcagaat
3661 ttttccagcc ttcacacaca aagcagtaaa caattgtaaa ttgagtaatt attagtaggc
3721 ttagctattc tagggttgcc aacactacac actgtgctat tcaccagaga gtcacaatat
3781 ttgacaggac taatagtctg ctagctggca caggctgccc actttgcgat ggatgccaga
3841 aaacccaggc atgaacagga atcggccagc caggctgcca gccacaaggt actggcacag
3901 gctccaacga gaggtcccac tctggctttc ccacctgata ataaagtgtc aaagcagaaa
3961 gactggtaaa gtgtggtata agaaaagaac cactgaatta aattcaccta gtgttgcaaa
4021 tgagtactta tctctaagtt ttcttttacc ataaaaagag agcaagtgtg atatgttgaa
4081 tagaaagaga aacatactat ttacagctgc cttttttttt tttttcgcta tcaatcacag
4141 gtatacaagt acttgccttt actcctgcat gtagaagact cttatgagcg agataatgca
4201 gagaaggcct ttcatataaa tttatacagc tctgagctgt tcttcttcta gggtgccttt
4261 tcattaagag gtaggcagta ttattattaa agtacttagg atacattggg gcagctagga
4321 catattcagt atcattcttg ctccatttcc aaattattca tttctaaatt agcatgtaga
4381 agttcactaa ataatcatct agtggcctgg cagaaatagt gaatttccct aagtgccttt
4441 tttttgttgt ttttttgttt tgttttttaa acaagcagta ggtggtgctt tggtcataag
4501 ggaagatata gttttctagg actattccat attttccatg tggctggata ctaactattt
4561 gccagcctcc ttttctaaat tgtgagacat tcttggagga acagttctaa ctaaaatcta
4621 ttatgactcc ccaagtttta aaatagctaa atttagtaag ggaaaaaata gtttatgttt
4681 tagaagactg aacttagcaa actaacctga attttgtgct ttgtgaaatt ttatatcgaa
4741 atgagctttc ccattttcac ccacatgtaa tttacaaaat agttcattac aattatctgt
4801 acattttgat attgaggaaa aacaaggctt aaaaaccatt atccagtttg cttggcgtag
4861 acctgtttaa aaaataataa accgttcatt tctcaggatg tggtcataga ataaagttat
4921 gctcaaatgt taaaaaaaaa aaaaaaaaaa aaaaaaa
//