LOCUS BC146759 5174 bp mRNA linear HUM 12-JUL-2007
DEFINITION Homo sapiens slit homolog 3 (Drosophila), mRNA (cDNA clone
MGC:166827 IMAGE:9007197), complete cds.
ACCESSION BC146759
VERSION BC146759.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5174)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5174)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 9 Row: c Column: 10.
FEATURES Location/Qualifiers
source 1..5174
/db_xref="H-InvDB:HIT000435551"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:166827 IMAGE:9007197"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+"
gene 1..5174
/gene="SLIT3"
/gene_synonym="MEGF5"
/gene_synonym="Slit-3"
/gene_synonym="SLIT1"
/gene_synonym="slit2"
/db_xref="GeneID:6586"
/db_xref="HGNC:HGNC:11087"
/db_xref="MIM:603745"
CDS 421..4992
/gene="SLIT3"
/gene_synonym="MEGF5"
/gene_synonym="Slit-3"
/gene_synonym="SLIT1"
/gene_synonym="slit2"
/codon_start=1
/product="slit homolog 3 (Drosophila)"
/protein_id="AAI46760.1"
/db_xref="GeneID:6586"
/db_xref="HGNC:HGNC:11087"
/db_xref="MIM:603745"
/translation="MAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAAS
VDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIER
GAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVK
NLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLY
CDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNAN
SISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK
RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKIN
CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD
YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK
CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSN
NKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDT
FAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR
IVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSN
KGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNM
SHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGT
NPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV
AKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHL
SDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGEL
CDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQ
CVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCP
PGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPL
ALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSL
GKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA
LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCH
HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQP
GFSGEHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKR
RKYVFQCTDGSSFVEEVERHLECGCLACS"
BASE COUNT 1150 a 1691 c 1424 g 909 t
ORIGIN
1 gagagcgagc gccggccagc tcacccggcc gccccgtgcc ccagccgcag ccgccgcgct
61 ccccagccca gccccaagcc ggacctcccc gggcgccacg ccccattgcg ctcgccccag
121 gtccccaacc cggcccgcgg gccagcgggg ccagggggcg ctccgcacct gggcactccc
181 agcgatgcgc agcggggcag cgccggcccc gccgatggag ctgctgttgc tgccgccgcc
241 gccgcccgga gcgccccgct ccgcccgcgc cccgtgcgcc tgagcaccga gctcgcccct
301 cctccgcgct aactccgccg cccgctcccc aggccgcccg cgctccccgc gcgcctcctc
361 gggctccacg cgtcttgccc cgcagaggca gcctcctcca ggagcggggc cctgcacacc
421 atggcccccg ggtgggcagg ggtcggcgcc gccgtgcgcg cccgcctggc gctggccttg
481 gcgctggcga gcgtcctgag tgggcctcca gccgtcgcct gccccaccaa gtgtacctgc
541 tccgctgcca gcgtggactg ccacgggctg ggcctccgcg cggttcctcg gggcatcccc
601 cgcaacgctg agcgccttga cctggacaga aataatatca ccaggatcac caagatggac
661 ttcgctgggc tcaagaacct ccgagtcttg catctggaag acaaccaggt cagcgtcatc
721 gagagaggcg ccttccagga cctgaagcag ctagagcgac tgcgcctgaa caagaataag
781 ctgcaagtcc ttccagaatt gcttttccag agcacgccga agctcaccag actagatttg
841 agtgaaaacc agatccaggg gatcccgagg aaggcgttcc gcggcatcac cgatgtgaag
901 aacctgcaac tggacaacaa ccacatcagc tgcattgaag atggagcctt ccgagcgctg
961 cgcgatttgg agatccttac cctcaacaac aacaacatca gtcgcatcct ggtcaccagc
1021 ttcaaccaca tgccgaagat ccgaactctg cgcctccact ccaaccacct gtactgcgac
1081 tgccacctgg cctggctctc ggattggctg cgacagcgac ggacagttgg ccagttcaca
1141 ctctgcatgg ctcctgtgca tttgaggggc ttcaacgtgg cggatgtgca gaagaaggag
1201 tacgtgtgcc cagcccccca ctcggagccc ccatcctgca atgccaactc catctcctgc
1261 ccttcgccct gcacgtgcag caataacatc gtggactgtc gaggaaaggg cttgatggag
1321 attcctgcca acttgccgga gggcatcgtc gaaatacgcc tagaacagaa ctccatcaaa
1381 gccatccctg caggagcctt cacccagtac aagaaactga agcgaataga catcagcaag
1441 aatcagatat cggatattgc tccagatgcc ttccagggcc tgaaatcact cacatcgctg
1501 gtcctgtatg ggaacaagat caccgagatt gccaagggac tgtttgatgg gctggtgtcc
1561 ctacagctgc tcctcctcaa tgccaacaag atcaactgcc tgcgggtgaa cacgtttcag
1621 gacctgcaga acctcaactt gctctccctg tatgacaaca agctgcagac catcagcaag
1681 gggctcttcg cccctctgca gtccatccag acactccact tagcccaaaa cccatttgtg
1741 tgcgactgcc acttgaagtg gctggccgac tacctccagg acaaccccat cgagacaagc
1801 ggggcccgct gcagcagccc gcgccgactc gccaacaagc gcatcagcca gatcaagagc
1861 aagaagttcc gctgctcagg ctccgaggat taccgcagca ggttcagcag cgagtgcttc
1921 atggacctcg tgtgccccga gaagtgtcgc tgtgagggca cgattgtgga ctgctccaac
1981 cagaagctgg tccgcatccc aagccacctc cctgaatatg tcaccgacct gcgactgaat
2041 gacaatgagg tatctgttct ggaggccact ggcatcttca agaagttgcc caacctgcgg
2101 aaaataaatc tgagtaacaa taagatcaag gaggtgcgag agggagcttt cgatggagca
2161 gccagcgtgc aggagctgat gctgacaggg aaccagctgg agaccgtgca cgggcgcgtg
2221 ttccgtggcc tcagtggcct caaaaccttg atgctgagga gtaacttgat cggctgtgtg
2281 agtaatgaca cctttgccgg cctgagttcg gtgagactgc tgtccctcta tgacaatcgg
2341 atcaccacca tcacccctgg ggccttcacc acgcttgtct ccctgtccac cataaacctc
2401 ctgtccaacc ccttcaactg caactgccac ctggcctggc tcggcaagtg gttgaggaag
2461 aggcggatcg tcagtgggaa ccctaggtgc cagaagccat ttttcctcaa ggagattccc
2521 atccaggatg tggccatcca ggacttcacc tgtgatggca acgaggagag tagctgccag
2581 ctgagcccgc gctgcccgga gcagtgcacc tgtatggaga cagtggtgcg atgcagcaac
2641 aaggggctcc gcgccctccc cagaggcatg cccaaggatg tgaccgagct gtacctggaa
2701 ggaaaccacc taacagccgt gcccagagag ctgtccgccc tccgacacct gacgcttatt
2761 gacctgagca acaacagcat cagcatgctg accaattaca ccttcagtaa catgtctcac
2821 ctctccactc tgatcctgag ctacaaccgg ctgaggtgca tccccgtcca cgccttcaac
2881 gggctgcggt ccctgcgagt gctaaccctc catggcaatg acatttccag cgttcctgaa
2941 ggctccttca acgacctcac atctctttcc catctggcgc tgggaaccaa cccactccac
3001 tgtgactgca gtcttcggtg gctgtcggag tgggtgaagg cggggtacaa ggagcctggc
3061 atcgcccgct gcagtagccc tgagcccatg gctgacaggc tcctgctcac caccccaacc
3121 caccgcttcc agtgcaaagg gccagtggac atcaacattg tggccaaatg caatgcctgc
3181 ctctccagcc cgtgcaagaa taacgggaca tgcacccagg accctgtgga gctgtaccgc
3241 tgtgcctgcc cctacagcta caagggcaag gactgcactg tgcccatcaa cacctgcatc
3301 cagaacccct gtcagcatgg aggcacctgc cacctgagtg acagccacaa ggatgggttc
3361 agctgctcct gccctctggg ctttgagggg cagcggtgtg agatcaaccc agatgactgt
3421 gaggacaacg actgcgaaaa caatgccacc tgcgtggacg ggatcaacaa ctacgtgtgt
3481 atctgtccgc ctaactacac aggtgagcta tgcgacgagg tgattgacca ctgtgtgcct
3541 gagctgaacc tctgtcagca tgaggccaag tgcatccccc tggacaaagg attcagctgc
3601 gagtgtgtcc ctggctacag cgggaagctc tgtgagacag acaatgatga ctgtgtggcc
3661 cacaagtgcc gccacggggc ccagtgcgtg gacacaatca atggctacac atgcacctgc
3721 ccccagggct tcagtggacc cttctgtgaa caccccccac ccatggtcct actgcagacc
3781 agcccatgcg accagtacga gtgccagaac ggggcccagt gcatcgtggt gcagcaggag
3841 cccacctgcc gctgcccacc aggcttcgcc ggccccagat gcgagaagct catcactgtc
3901 aacttcgtgg gcaaagactc ctacgtggaa ctggcctccg ccaaggtccg accccaggcc
3961 aacatctccc tgcaggtggc cactgacaag gacaacggca tccttctcta caaaggagac
4021 aatgaccccc tggcactgga gctgtaccag ggccacgtgc ggctggtcta tgacagcctg
4081 agttcccctc caaccacagt gtacagtgtg gagacagtga atgatgggca gtttcacagt
4141 gtggagctgg tgacgctaaa ccagaccctg aacctagtag tggacaaagg aactccaaag
4201 agcctgggga agctccagaa gcagccagca gtgggcatca acagccccct ctaccttgga
4261 ggcatcccca cctccaccgg cctctctgcc ttgcgccagg gcacggaccg gcctctaggc
4321 ggcttccacg gatgcatcca tgaggtgcgc atcaacaacg agctgcagga cttcaaggcc
4381 ctcccaccac agtccctggg ggtgtcacca ggctgcaagt cctgcaccgt gtgcaagcac
4441 ggcctgtgcc gctccgtgga gaaggacagc gtggtgtgcg agtgccgccc aggctggacc
4501 ggcccactct gcgatcagga ggcccgggac ccctgcctcg gccacagatg ccaccatgga
4561 aaatgtgtgg caactgggac ctcatacatg tgcaagtgtg ccgagggcta tggaggggac
4621 ttgtgtgaca acaagaatga ctctgccaat gcctgctcag ccttcaagtg tcaccatggg
4681 cagtgccaca tctcagacca aggggagccc tactgcctgt gccagcccgg ctttagcggc
4741 gagcactgcc aacaagagaa tccgtgcctg ggacaagtag tccgagaggt gatccgccgc
4801 cagaaaggtt atgcatcatg tgccacagcc tccaaggtgc ccatcatgga atgtcgtggg
4861 ggctgtgggc cccagtgctg ccagcccacc cgcagcaagc ggcggaaata cgtcttccag
4921 tgcacggacg gctcctcgtt tgtagaagag gtggagagac acttagagtg cggctgcctc
4981 gcgtgttcct aagcccctgc ccgcctgcct gccacctctc ggactccagc ttgatggagt
5041 tgggacagcc atgtgggacc ccctggtgat tcagcatgaa ggaaatgaag ctggagagga
5101 aggtaaagaa gaagagaata ttaagtatat tgtaaaataa acaaaaaata gaacttaaaa
5161 aaaaaaaaaa aaaa
//