LOCUS BC146658 1932 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens ADAM metallopeptidase domain 17, mRNA (cDNA clone
IMAGE:40147999), complete cds.
ACCESSION BC146658
VERSION BC146658.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1932)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1932)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: f Column: 14
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1932
/db_xref="H-InvDB:HIT000435522"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40147999"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..1932
/gene="ADAM17"
/gene_synonym="CD156b"
/gene_synonym="cSVP"
/db_xref="GeneID:6868"
/db_xref="HGNC:HGNC:195"
/db_xref="MIM:603639"
CDS 188..964
/gene="ADAM17"
/gene_synonym="CD156b"
/gene_synonym="cSVP"
/codon_start=1
/product="ADAM17 protein"
/protein_id="AAI46659.1"
/db_xref="GeneID:6868"
/db_xref="HGNC:HGNC:195"
/db_xref="MIM:603639"
/translation="MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDI
LSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGK
NESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTK
DKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADP
DPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIHTDRAN"
BASE COUNT 586 a 371 c 437 g 538 t
ORIGIN
1 cgccacctgc acttctgggg gcgtcgagcc tggcggtaga atcttcccag taggcggcgc
61 gggagggaaa agaggattga ggggctaggc cgggcggatc ccgtcctccc ccgatgtgag
121 cagttttccg aaaccccgtc aggcgaaggc tgcccagaga ggtggagtcg gtagcggggc
181 cgggaacatg aggcagtctc tcctattcct gaccagcgtg gttcctttcg tgctggcgcc
241 gcgacctccg gatgacccgg gcttcggccc ccaccagaga ctcgagaagc ttgattcttt
301 gctctcagac tacgatattc tctctttatc taatatccag cagcattcgg taagaaaaag
361 agatctacag acttcaacac atgtagaaac actactaact ttttcagctt tgaaaaggca
421 ttttaaatta tacctgacat caagtactga acgtttttca caaaatttca aggtcgtggt
481 ggtggatggt aaaaacgaaa gcgagtacac tgtaaaatgg caggacttct tcactggaca
541 cgtggttggt gagcctgact ctagggttct agcccacata agagatgatg atgttataat
601 cagaatcaac acagatgggg ccgaatataa catagagcca ctttggagat ttgttaatga
661 taccaaagac aaaagaatgt tagtttataa atctgaagat atcaagaatg tttcacgttt
721 gcagtctcca aaagtgtgtg gttatttaaa agtggataat gaagagttgc tcccaaaagg
781 gttagtagac agagaaccac ctgaagagct tgttcatcga gtgaaaagaa gagctgaccc
841 agatcccatg aagaacacgt gtaaattatt ggtggtagca gatcatcgct tctacagata
901 catgggcaga ggggaagaga gtacaactac aaattactta atacacacag atagagctaa
961 ttgacagagt tgatgacatc tatcggaaca cttcatggga taatgcaggt tttaaaggct
1021 atggaataca gatagagcag ttattatttg aataggtaac atgtacacag tacaaaagcc
1081 agtgaaaagt aagtctctgc agcctgttta ttgtcaaacc agttcctttc cccaaagaca
1141 ttcatgtcac tagtttcata tgtatctttc tagagatgtc gtatgcaggt atagtgtatg
1201 tatatgtctg tatttgacac aacggtgcta tgcagtacac ttttacacct tgctttttca
1261 tttcacagta tgttggagag tacttcatgt tcatgcatgt aaagctgctt cacttgtttt
1321 attataaata gctgcatcat gtttgagttt cagggaacct gtaaattttt ctttttgctt
1381 taggcatttg gaaccagtcg aagaaacagg aataatatag gagattaaaa cattaacttc
1441 tttacatctg atgaaggatg gattggaggg tgtggtttag atgtgtatca tggtgggctt
1501 ctaagtagtt ctatcccaga tttgaccttg accagccacc atcaaaactg cagagtccac
1561 cccagtaaac ttaccacaca gtggcagagg agaccagaat gggccttctc tgcaggcagg
1621 caggcaggca ggcaggcaga gagactcaca gaaactctga gctgagcatg gtttccttct
1681 ttatctcaca cttactaatg ggagcctttg ttactttttt ttttcttctt tgcaggttta
1741 atatgaattt gtctgaaatg cctgtataag gagaagactc tattcttagc cttttattcc
1801 tttgatgcac aaagagatgt atattttatt attctttcct gagttgtcga ctgtagtcgt
1861 aataaatatt ttaggctcct gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1921 aaaaaaaaaa aa
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