LOCUS BC144591 5476 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens laminin, beta 4, mRNA (cDNA clone MGC:178138
IMAGE:9053121), complete cds.
ACCESSION BC144591
VERSION BC144591.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5476)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5476)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 677 Row: k Column: 7
isoform, single-stranded.
FEATURES Location/Qualifiers
source 1..5476
/db_xref="H-InvDB:HIT000502996"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:178138 IMAGE:9053121"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: TCCTCTAT"
gene 1..5476
/gene="LAMB4"
/db_xref="GeneID:22798"
/db_xref="HGNC:HGNC:6491"
CDS 72..5357
/gene="LAMB4"
/codon_start=1
/product="laminin, beta 4"
/protein_id="AAI44592.1"
/db_xref="GeneID:22798"
/db_xref="HGNC:HGNC:6491"
/translation="MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLM
ASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREK
KWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFA
KDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQ
DLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRP
MQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSC
NSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYAC
IPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPL
GCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDC
DIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAP
LGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFTIAI
HYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQSFALPAATRIMLLPTPICLEPDV
QYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQLHNCVEIAS
AMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRC
CDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFG
FPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCP
DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGTPCQPCAC
NNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVS
PMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQ
SSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGM
CRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANME
DKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQL
KAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS
AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGD
PGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQV
RGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENV
PPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKL
LVKAKAAEKAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQ
TREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVE
LKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNL
SRQAKADQLRILEDQVVAIKNEIVEQEKKYARCYS"
BASE COUNT 1521 a 1306 c 1319 g 1330 t
ORIGIN
1 tgctgcctga acctctccac aaagactccc agatcctgta gaattgaatt taatcatctc
61 ctgacaaaag aatgcaattt caactgaccc tttttttgca ccttgggtgg ctcagttact
121 caaaagctca agatgactgc aacaggggtg cctgtcatcc caccactggt gatctcctgg
181 tgggcaggaa cacgcagctt atggcttctt ctacctgtgg gctgagcaga gcccagaaat
241 actgcatcct cagttacctg gagggggaac aaaaatgctt catctgtgac tctagatttc
301 catatgatcc gtatgaccaa cccaacagcc acaccattga gaatgtcatt gtaagttttg
361 aaccagacag agaaaagaaa tggtggcaat ctgaaaatgg tcttgatcat gtcagcatca
421 gactggactt agaggcatta tttcggttca gccaccttat cctgaccttt aagacttttc
481 ggcctgctgc aatgttagtt gaacgttcca cagactatgg acacaactgg aaagtgttca
541 aatattttgc aaaagactgt gccacttcct ttcctaacat cacatctggc caggcccagg
601 gagtgggaga cattgtttgt gactccaaat actcggatat tgaaccctca acaggtggag
661 aggttgtttt aaaagttttg gatcccagtt ttgaaattga aaacccttat agcccctaca
721 tccaagacct tgtgacattg acaaacctga ggataaactt taccaagctc cacacccttg
781 gggatgcttt gcttggaagg aggcaaaatg attcccttga taaatactac tatgctctgt
841 acgagatgat tgttcgggga agctgctttt gcaatggcca tgctagcgaa tgtcgcccta
901 tgcagaagat gcggggagat gttttcagcc ctcctggaat ggttcacggt cagtgtgtgt
961 gtcagcacaa tacagatggt ccgaactgtg agagatgcaa ggacttcttc caggatgctc
1021 cttggaggcc agctgcagac ctccaggaca acgcttgcag atcgtgcagc tgtaatagcc
1081 actccagccg ctgtcacttt gacatgacta cgtacctggc aagcggtggc ctcagcgggg
1141 gcgtgtgtga agactgccag cacaacactg aggggcagca ctgcgaccgc tgcagacccc
1201 tcttctacag ggacccgctc aagaccatct cagatcccta cgcgtgcatt ccttgtgaat
1261 gtgaccccga tgggaccata tctggtggca tttgtgtgag ccactctgat cctgccttag
1321 ggtctgtggc cggccagtgc ctttgtaaag agaacgtgga aggagccaaa tgcgaccagt
1381 gcaaacccaa ccactacgga ctaagcgcca ccgaccccct gggctgccag ccctgcgact
1441 gtaaccccct tgggagtctg ccattcttga cctgtgatgt ggatacaggc caatgcttgt
1501 gcctgtcata tgtcaccgga gcacactgcg aagaatgcac tgttggatac tggggcctgg
1561 gaaatcatct ccatgggtgt tctccctgtg actgtgatat tggaggtgct tattctaacg
1621 tgtgctcacc caagaatggg cagtgtgaat gccgcccaca tgtcactggc cgtagctgct
1681 ctgaaccagc ccctggctac ttctttgctc ctttgaattt ctatctctac gaggcagagg
1741 aagccacaac actccaagga ctggcgcctt tgggctcgga gacgtttggc cagagtcctg
1801 ctgttcacgt tgttttagga gagccagttc ctgggaaccc tgttacatgg actggacctg
1861 gatttgccag ggttctccct ggggctggct tgagatttgc tgtcaacaac attccctttc
1921 ctgtggactt caccattgcc attcactatg aaacccagtc tgcagctgac tggactgtcc
1981 agattgtggt gaacccccct ggagggagtg agcactgcat acccaagact ctacagtcaa
2041 agcctcagtc ttttgcctta ccagcggcta cgagaatcat gctgcttccc acacccatct
2101 gtttagaacc agatgtacaa tattccatag atgtctattt ttctcagcct ttgcaaggag
2161 agtcccacgc tcattcacat gtcctggtgg actctcttgg ccttattccc caaatcaatt
2221 cattggagaa tttctgcagc aagcaggact tagatgagta tcagcttcac aactgtgttg
2281 aaattgcctc agcaatggga cctcaagtgc tcccgggtgc ctgtgaaagg ctgatcatca
2341 gcatgtctgc caagctgcat gatggggctg tggcctgcaa gtgtcacccc cagggctcag
2401 tcggatccag ctgcagccga cttggaggcc agtgccagtg taaacctctt gtggtcgggc
2461 gctgctgtga caggtgctca actggaagct atgatttggg gcatcacggc tgtcacccat
2521 gtcactgcca tcctcaagga tcaaaggaca ctgtatgtga ccaagtaaca ggacagtgcc
2581 cctgccatgg agaggtgtct ggccgccgct gtgatcgctg cctggcaggc tactttggat
2641 ttcccagctg ccacccttgc ccttgtaata ggtttgctga actttgtgat cctgagacag
2701 ggtcatgctt caattgtgga ggctttacaa ctggcagaaa ctgtgaaagg tgtattgatg
2761 gttactatgg aaatccttct tcaggacagc cctgtcgtcc ttgcctgtgt ccagatgatc
2821 cctcaagcaa tcagtatttt gcccattcct gttatcagaa tctgtggagc tcagatgtaa
2881 tctgcaattg tcttcaaggt tatacgggta ctcagtgtgg agaatgctct actggtttct
2941 atggaaatcc aagaatttca ggaacacctt gccaaccatg tgcctgcaac aacaacatag
3001 atgtaaccga tccagagtcc tgcagccggg taacagggga gtgccttcga tgtttgcaca
3061 acactcaggg cgcaaactgc cagctctgca aaccaggtca ctatggatca gccctcaatc
3121 agacctgcag aagatgctcc tgccatgctt ccggcgtgag tcccatggag tgtccccctg
3181 gtgggggagc ttgcctctgt gaccctgtca ctggtgcatg tccttgtctg ccgaatgtca
3241 caggcctggc ctgtgaccgt tgtgctgatg gatactggaa tctggtccct ggcagaggat
3301 gtcagtcatg tgactgtgac cctaggacct ctcaaagtag ccactgtgac cagcttacag
3361 gccagtgtcc gtgtaaatta ggttacggcg ggaaacgttg cagtgagtgc caggaaaatt
3421 attatggtga tccacctggg cgatgcattc catgtgattg taacagggca ggtacccaga
3481 agcccatctg tgatccagac acaggcatgt gccgctgccg ggagggtgtc agcggccaga
3541 gatgtgatcg ctgtgcccgg ggacacagcc aggaattccc tacttgtctt caatgtcact
3601 tgtgctttga tcagtgggac cacaccattt cttccctctc caaagcggtg caagggttaa
3661 tgagactggc tgctaacatg gaagataaaa gagagaccct gcctgtctgt gaggcagact
3721 tcaaagacct cagagggaac gtgtctgaaa tagaaaggat tttgaaacat cctgttttcc
3781 catctgggaa attcttaaaa gtcaaggatt atcatgactc tgttagaaga caaatcatgc
3841 agctaaatga acaactgaaa gcagtgtatg aatttcaaga tctgaaagat acaatagaaa
3901 gagcaaagaa tgaagcagac ctcttacttg aagaccttca ggaagaaatt gatttgcaat
3961 ccagtgtcct taatgcaagc attgcggact cctcagaaaa catcaagaaa tattatcaca
4021 tatcatcatc tgctgaaaag aaaattaatg aaactagttc caccattaat acctctgcaa
4081 atacaaggaa tgacttactt accatcttag atacactaac ctcaaaagga aacttgtcat
4141 tggaaagatt aaagcagatt aagataccag atatccaaat attgaatgaa aaggtgtgcg
4201 gagatccagg aaatgtgcca tgtgtgccct tgccctgtgg cggtgctctc tgcacgggcc
4261 ggaaggggca caggaagtgt aggggtcccg gctgtcacgg ctccctgacc ctctcaacga
4321 atgccctcca aaaagcccag gaagcaaaat ccattattcg taatttggac aaacaggttc
4381 gtgggttgaa aaatcagatc gaaagtataa gtgaacaggc agaagtctcc aaaaacaatg
4441 ccttacagct gagggaaaaa ctgggaaata taagaaacca aagtgactct gaagaagaaa
4501 acatcaatct tttcatcaaa aaagtgaaaa actttttgtt agaggaaaac gtgcctccag
4561 aagacatcga gaaggttgcg aatggtgtgc ttgacattca cctaccaatt ccatcccaaa
4621 atctaaccga tgaacttgtc aaaatacaga aacatatgca actctgtgag gattacagga
4681 cagatgaaaa caggttaaat gaagaagcag atggagccca aaagcttttg gtgaaggcca
4741 aagcagctga gaaagcagca aatattctat taaatcttga caaaacattg aaccagttac
4801 aacaagctca aatcactcaa ggacgggcaa actctaccat tacacagctg actgccaata
4861 taacaaaaat aaaaaagaat gtgctgcagg ctgaaaatca aaccagggaa atgaagagtg
4921 agctggagtt agcaaagcag cgatcagggc tggaggatgg actttccctg ctgcagacca
4981 agttgcaaag gcatcaagac cacgctgtca atgcgaaagt tcaggctgaa tctgcccaac
5041 accaggctgg gagtcttgag aaggaatttg ttgagctgaa aaaacaatat gctattctcc
5101 aacgtaagac aagcactaca ggactaacaa aggagacatt aggaaaagtt aaacagctaa
5161 aagatgcggc agaaaaattg gctggagata cagaggccaa gataagaaga ataacagatt
5221 tagaaaggaa aatccaagat ttgaatctaa gtagacaagc aaaagctgat caactgagaa
5281 tattggaaga tcaagttgtt gccattaaaa atgaaattgt tgaacaagaa aaaaaatatg
5341 ctaggtgcta tagctaggca gagttaaaga gcaaaagctt gtgcctttgt ttctggtttc
5401 tgatgtacaa gcccctgggg ctctgttgaa cctgtgaaat actgacaatg tcttctacct
5461 tccttcccca caccct
//