LOCUS BC144563 2799 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens inositol 1,4,5-triphosphate receptor, type 1, mRNA
(cDNA clone IMAGE:9053091), complete cds.
ACCESSION BC144563
VERSION BC144563.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2799)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2799)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 677 Row: j Column: 1
This clone has the following problem: The cds is short compared to
the longest cds in the locus
isoform, single-stranded.
FEATURES Location/Qualifiers
source 1..2799
/db_xref="H-InvDB:HIT000502969"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:9053091"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_312"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: CCCCGTTT"
gene 1..2799
/gene="ITPR1"
/gene_synonym="INSP3R1"
/gene_synonym="IP3R"
/gene_synonym="IP3R1"
/db_xref="GeneID:3708"
/db_xref="HGNC:HGNC:6180"
/db_xref="MIM:147265"
CDS 149..2314
/gene="ITPR1"
/gene_synonym="INSP3R1"
/gene_synonym="IP3R"
/gene_synonym="IP3R1"
/codon_start=1
/product="ITPR1 protein"
/protein_id="AAI44564.1"
/db_xref="GeneID:3708"
/db_xref="HGNC:HGNC:6180"
/db_xref="MIM:147265"
/translation="MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETG
DLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQ
NETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSW
FYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSW
KIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSAT
SSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVC
NKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLV
YREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETA
VPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVT
VLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFAD
LRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDS
TEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTN
LSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA"
BASE COUNT 787 a 590 c 691 g 731 t
ORIGIN
1 ctaacccctc tcctcgccct gctcccccaa accggcgtgg ctccccgggc accaaggagc
61 tgactacaga ggagcaggat ttgcacccct cgctgggctt gctttggcaa cagagtgcct
121 gacccaggtc aggattttca agaaagacat gtctgacaaa atgtctagct tcctacatat
181 tggagacatt tgttctctgt acgcggaggg atcgacaaat ggatttatta gcaccttggg
241 cctggttgat gatcgttgtg ttgtacagcc agaaaccggg gaccttaaca atccacctaa
301 gaaattcaga gactgcctct ttaagctatg tcccatgaac cgctactctg cccaaaagca
361 gttctggaaa gccgctaagc ctggggccaa cagcaccaca gacgcagtgc tactcaacaa
421 actgcaccac gctgcagact tggaaaagaa gcagaatgag acagaaaaca ggaaattgct
481 ggggaccgta atccagtatg gcaatgtgat ccagctcctg catttgaaaa gtaataaata
541 cctaacagtg aataagaggc ttcctgctct gttggagaag aatgccatga gagtcacatt
601 ggacgaggct ggaaatgaag ggtcctggtt ttatattcag ccattctaca agctgcgatc
661 cattggagac agcgtggtca taggtgacaa ggtggttctg aaccccgtca atgctggtca
721 gcccctacat gctagcagcc atcaactggt agataaccca ggctgcaatg aggtcaattc
781 cgtcaactgc aatacaagct ggaaaatagt ccttttcatg aaatggagtg ataacaaaga
841 cgacatatta aaggggggtg acgtggtgag gctgtttcat gctgagcagg agaagtttct
901 cacctgtgac gaacacagga agaagcagca cgtcttcctg agaaccacgg gccggcagtc
961 ggccacatct gccaccagtt caaaagccct gtgggaggtg gaggtggtcc agcatgaccc
1021 atgtcggggc ggagcagggt attggaacag ccttttccgt ttcaagcatc tggccacggg
1081 gcattacttg gcagcagagg tagaccctga ctttgaggaa gaatgcctgg agtttcagcc
1141 ctcagtatgc aataaaatca tctttctaat gagctttgtg ggcaactgtg ggacattcac
1201 aagaggctac cgagccatgg ttctggatgt tgagttcctc tatcatttgt tgtatctggt
1261 gatctgtgcc atggggctct ttgtccatga attcttctac agtctgctgc tttttgattt
1321 agtgtacaga gaagagactt tgcttaatgt cattaaaagt gtcactcgca atggacggtc
1381 catcatcctg acagcagttc tggctctgat cctcgtttac ctgttctcaa tagtgggcta
1441 tcttttcttc aaggatgact ttatcttgga agtagatagg ctgcccaatg aaacagctgt
1501 tccagaaacc ggcgagagtt tggcaagcga gttcctgttc tccgatgtgt gtagggtgga
1561 gagtggggag aactgctcct ctcctgcacc cagagaagag ctggtccctg cagaagagac
1621 ggaacaggat aaagagcaca catgtgagac gctgctgatg tgcattgtca ccgtgctgag
1681 tcacgggctg cggagcgggg gtggagtagg agatgtactc aggaagccgt ccaaagagga
1741 acccctgttt gctgctagag ttatttatga cctcttgttc ttcttcatgg tcatcatcat
1801 tgttcttaac ctgatttttg gggttatcat tgacactttt gctgacctga ggagtgagaa
1861 gcagaagaag gaagagatct tgaagaccac gtgctttatc tgtggcttgg aaagagacaa
1921 gtttgacaac aagactgtca cctttgaaga gcacatcaag gaagaacaca acatgtggca
1981 ctatctgtgc ttcatcgtcc tggtgaaagt aaaggactcc accgaatata ctgggcctga
2041 gagttacgtg gcagaaatga tcaaggaaag aaaccttgac tggttcccca ggatgagagc
2101 catgtcattg gtcagcagtg attctgaagg agaacagaat gagctgagaa acctgcagga
2161 gaagctggag tccaccatga aacttgtcac gaacctttct ggccagctgt cggaattaaa
2221 ggatcagatg acagaacaaa ggaagcagaa acaaagaatt ggtcttctag gacatcctcc
2281 tcacatgaat gtcaacccac aacaaccagc ataagcaaat gaaagaaagg aattgtattt
2341 accttttata attattatta gtgtgggtat ggctaatgag ttctgattca cccacgaagg
2401 ttacatttat gctgaataca tttgtaaata ctcagtttta tactgtatgt atatgattgc
2461 tactctaaag gtttggatat atgtattgta attagaattg ttggcatgat gacatttcat
2521 ttgtgccaaa aatattaaaa atgccttttt tggaaggact aacagaaagc acctgatttg
2581 cacttgaacc agattataga tttaaaagta tatgacatgt attttgtatt taaaactaga
2641 atagccagta tttatgtttt ttataaaact gtgcaatacg aattatgcaa tcacaataca
2701 tttgtagctc ccgagtgtcc taaagggagt gcacttcttt gaagctggtg tgttaatact
2761 atgtaataaa tggttaactt tcaaatgatg ctgctgcca
//