LOCUS BC144482 4639 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens TBC1 domain family, member 2B, mRNA (cDNA clone
MGC:178026 IMAGE:9053009), complete cds.
ACCESSION BC144482
VERSION BC144482.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4639)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4639)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 18 Row: O Column: 17.
FEATURES Location/Qualifiers
source 1..4639
/db_xref="H-InvDB:HIT000502892"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:178026 IMAGE:9053009"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_313"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GATTGTCC"
gene 1..4639
/gene="TBC1D2B"
/db_xref="GeneID:23102"
/db_xref="HGNC:HGNC:29183"
CDS 24..2537
/gene="TBC1D2B"
/codon_start=1
/product="TBC1D2B protein"
/protein_id="AAI44483.1"
/db_xref="GeneID:23102"
/db_xref="HGNC:HGNC:29183"
/translation="MTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGDFPKGLVARDN
TDLIYPHPNASAEKARNVLAVETVPGELVGEQAANQPAPGHPNSINFYSLKQWGNELK
NSMSSFRPGRGHNDSRRTVFYTNEEWELLDPTPKDLEESIVQEEKKKLTPEGNKGVTG
SGFPFDFGRNPYKGKRPLKDIIWSYKNRHSSGDPSSEGTSGSGSVSIRKPASEMQLQV
QSQQEELEQLKKDLSSQKELVRLLQQTVRSSQYDKYFTSSRLCEVVPKDTLELLHQKD
DQILGLTSQLERFSLEKESLQQEVRTLKSKVGELNEQLGMLMETIQAKDEVIIKLSEG
EGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKEILELSALRRNAE
RRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSEDQGPTREVIAQLLEDALQVE
SQEQPEQAFVKPHLVSEYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTG
VKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHF
QTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIG
YCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSE
KLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALA
LFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQIRNRRAYH
LEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT"
BASE COUNT 1122 a 1136 c 1263 g 1118 t
ORIGIN
1 tcaaggctcc caatcgtcaa ctcatgactt actggttaca ggagcttcag cagaagagat
61 gggaatattg taacagtctt gacatggtca agtgggacag caggacctct ccaactcccg
121 gggattttcc taagggtctt gtagccagag ataacactga tttaatttac ccacacccaa
181 atgcttctgc agaaaaagcc agaaatgtcc tagctgtgga gactgtgcct ggagagctgg
241 tgggagaaca agctgcaaat cagcccgccc cagggcatcc aaattccatt aatttttact
301 ctttgaaaca gtggggcaat gagctcaaga attcgatgtc ttctttccgt cctgggagag
361 gacataatga tagtcggagg actgtgtttt ataccaatga agagtgggaa cttttagacc
421 caacccctaa ggacctagag gagtccatag tacaggaaga aaagaagaag ctgacccctg
481 aaggaaacaa aggagtaact ggctcaggat tcccctttga ttttggacgt aacccctaca
541 aaggaaagcg ccctttgaaa gacataattt ggtcgtacaa aaatcgtcac agcagtggtg
601 acccttcaag tgaaggcaca tcaggcagtg gcagcgtcag catcaggaag ccggcctccg
661 aaatgcaact gcaggtccag agccagcagg aagagctgga acagttaaag aaagacctgt
721 ccagtcagaa ggagcttgtt cgactgctcc agcagacagt ccggtcatcc cagtatgaca
781 agtatttcac aagcagccgg ctctgtgagg tggtcccaaa ggacacgctc gagcttctgc
841 accaaaagga tgatcagatt ctgggcctta ccagccagct ggagaggttc agcttggaga
901 aggagagtct tcagcaggaa gtaaggacgc tgaagagcaa agtgggcgag ctcaacgagc
961 agctgggaat gctcatggag accatccaag ccaaggacga ggtcatcatc aagctcagcg
1021 agggcgaggg caacgggcct cctcccaccg tggcgcccag ctccccttcg gttgtgcctg
1081 ttgccaggga ccagctggaa ctggacaggc tgaaagataa tctacagggg tacaaaaccc
1141 aaaacaaatt tctaaataag gagattttgg aactctcagc tctacgaaga aatgcagaaa
1201 ggagagagag ggatctgatg gcaaagtatt ctagcctgga agccaagctc tgccagatag
1261 aaagtaaata cctgatattg ctccaagaaa tgaagacacc agtgtgctca gaagaccagg
1321 ggcccacccg ggaggtcata gcccagttgc tggaggatgc tctgcaggtt gagagccaag
1381 agcagccgga gcaagcattt gttaaacctc atcttgtcag tgaatatgat atttatgggt
1441 tcaggactgt acctgaggat gatgaggaag agaaattggt tgccaaggtc cgcgcgttgg
1501 atctgaagac tctctacctc acagaaaacc aggaagtctc cactggggtc aagtgggaaa
1561 actattttgc aagtacagtg aacagggaga tgatgtgctc tccagagtta aaaaacctca
1621 tccgtgcggg cattccccac gagcaccgtt ccaaggtgtg gaagtggtgt gtggaccgtc
1681 acaccaggaa gttcaaggac aacactgagc ctggccactt ccagaccttg ctgcagaagg
1741 cgctggagaa acagaaccca gcctccaagc agattgagct ggacttgctg cgaactctgc
1801 ccaacaacaa acattactcc tgccccacct cagaaggcat acagaagtta cgcaatgtcc
1861 tcctcgcctt ctcctggcgg aatccagata tcggctactg tcaaggccta aacaggttgg
1921 tggcagtggc cctcctgtac ctggaacaag aagatgcttt ctggtgtctc gttaccatag
1981 tggaagtttt catgcctcga gactattata caaagactct tttaggatcc caggtggacc
2041 agcgggtgtt cagagacctt atgagtgaga agctgcctcg gttgcatggc cactttgaac
2101 agtacaaagt cgactacact ctcatcactt tcaactggtt tctggtggta tttgtggata
2161 gtgtcgttag tgacatcctc tttaaaatat gggactcttt cctttatgaa ggaccaaagg
2221 ttattttccg ttttgctctg gcacttttta agtacaagga agaggagatt ttgaaattgc
2281 aagattcgat gtctatattt aagtatctcc gctacttcac tcgcactatc cttgatgcta
2341 ggaagctgat cagtatctcc tttggggacc tgaacccttt ccccctacgc cagatccgga
2401 accgacgcgc ctaccacttg gagaaagtcc ggctggagct gaccgagctg gaggccatcc
2461 gtgaggactt cctgcgtgag cgggacacca gccctgacaa gggtgagctg gtcagtgacg
2521 aggaggagga tacctgagtg ggctcgggat gctgctcttc cttccttcac aaccaaagtg
2581 tgcccaaagg gtgaaagtgc acttaaaagc cagaatgtaa cgtgtgtgtc ctctggggat
2641 ctgctgggca gatgtcccaa gccaggctgc ccttcctcat ttcccactgt gcggggggca
2701 ggggtgggag gtctaatctg tttacaacca tttccgtgcc atgcttttgg ttacacgtat
2761 ctcagtcacg ctttctgcct ggttggtgga tcctcaggct taccagtggc tatttgcaag
2821 agcctgtttc cagcctccgt cagcctgtcg gtgctctgac cctctgaaac cttgctttgc
2881 tgggcatctc cccatattct ctctcctgta catagtgggc agtggtgtgt ggttttgaat
2941 ggcagtgcta taaaggatgc cagctgtgct ttaggcacct gtaggccaga gggttgctgc
3001 ctcaggcata aggttggtat gaaaaggggc tgccttagaa aagcaggcac atcccttgtt
3061 cagaaatggc cactgtagga aagcctgtga acctcccacc agtggcttta agctgccagc
3121 catgccccat ttctagaata gcctttgctc ttccacacgc aacccttcca tcagtgtctt
3181 ccagcctgca tggggagggc ctggctgccc agacacccac cctcacttct catggccagc
3241 ctgtgtttgc agatcactgg gctgctctgt ccccagcttg ccccgtgcca ggcatggctc
3301 tgtgagattc tgtggaatgc ccttcttgac ttgtggaaat cattcaccaa gtacgatggg
3361 atgggattcc aagtaaacag tggaccgtca tattgcaaag caggcccacg cctgggctgg
3421 ccttggttga ggggatggag gaatgttttc gggggtgctt tgcagggcag tggtgcagcc
3481 gcagcgtgaa cgctcttgga cagctgaaaa ccatggcctc cttggggatg gccagtgctc
3541 ctggtgtctc cacctgcctg ggttgtgcag gaggccggct gccagtgcct ggggctggga
3601 aacttttttg cttggggcag gcttgggtga gctctcccag atgtgtgccc accccaccac
3661 tgcctggaac atccttgttc tctgccagga tgcaggggca ctgttgcctc tgacacagca
3721 gtttctggga actcagagga ctgcctttct gaaggctggg gagaggcttt gagcaaggag
3781 cttgtttttg cttaatcgct ctagaccatc cctgatgtgt agatgtgaga ggatgttttc
3841 tggcacagtg ttatgaaaat acaagataaa tgatctcagt ggaatgtttc atattacccg
3901 aaaaaaactg gaaatcatcc tttgttgtga acacactgag actaagaatt gaagcaatgc
3961 agttttaaga agtatttttc ctattttttg ctgtcaactt tttggcaatg ccacggcaaa
4021 gttggtgttt cagcacatgc tagagtgagc tccggcttcg tgtctttaac caactccact
4081 aatgtttcac tgggtagacg gagctggcct ctatatttag ccagaagcct ttgcctcttt
4141 tcaggcatca aaaatgggtt ttgtcattgt ctttgtcttt gagagcagca gtttgaggtc
4201 tgactccttc agttgtcctg tgagctgggc gttgcagtct gctcgaatca agtgttggaa
4261 accccccacc cctcagccca tcgtgaaacg acagctgtca gcctgggggg cggctgctga
4321 ggaggtgcag caggaatggg gctgggccct gaggttttac tttccgagcc aatggcccct
4381 ggaacatgcc agcacacact gccatgtcct ggggctaaga gctgccttta gggacaggct
4441 cgtgttgtcc agtttgccct gagagatgca cctgaccagg ggcccgtcgt ggctgcaacc
4501 cacggtggta tgttagtgtt tccaggcagt tgtcagcagc tgccgggtag tgtgtgtgtg
4561 cgacagcagg agagttcctg gaggaaaggg actggggaca ctttctcaga ggttctcctg
4621 cctggaatca agtgatgcg
//