LOCUS BC144343 4707 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens SLIT-ROBO Rho GTPase activating protein 2, mRNA (cDNA
clone MGC:177880 IMAGE:9052863), complete cds.
ACCESSION BC144343
VERSION BC144343.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4707)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4707)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: J Column: 4.
FEATURES Location/Qualifiers
source 1..4707
/db_xref="H-InvDB:HIT000502763"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177880 IMAGE:9052863"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_363"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: GCCGTTAA"
gene 1..4707
/gene="SRGAP2"
/gene_synonym="srGAP3"
/db_xref="GeneID:23380"
/db_xref="HGNC:HGNC:19751"
/db_xref="MIM:606524"
CDS 71..3283
/gene="SRGAP2"
/gene_synonym="srGAP3"
/codon_start=1
/product="SRGAP2 protein"
/protein_id="AAI44344.1"
/db_xref="GeneID:23380"
/db_xref="HGNC:HGNC:19751"
/db_xref="MIM:606524"
/translation="MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQ
LLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLL
LNQVKRESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNEL
YSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEK
HVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLI
DCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNN
VFCPPMKFEFQPHMGDMASQLCAQQPVQSELVQRCQQLQSRLSTLKIENEEVKKTMEA
TLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYF
TKMKEYLEGRNLITKLQAKHDLLQKTLGESQRTDCSLARRSSTVRKQDSSQAIPLVVE
SCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKL
YFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNH
LSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQHENIFPSPR
ELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAEHHTSDDECEPIEAIAKFDYVG
RTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPKS
EIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKRPESGSIRKTFRSDSHGL
SSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGSLNSISRHSSLKNRLD
SPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELRELERQSSVKHTPDVV
LDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMA
APVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV"
BASE COUNT 1269 a 1235 c 1110 g 1093 t
ORIGIN
1 gacgcgtggg ttggattttt tccgtggatc tatcaattca caattcgaat ttggaagaaa
61 gaaggaaaac atgacgtctc cagccaaatt caaaaaggat aaggagatca tagcagagta
121 cgatactcag gtcaaagaga tccgtgctca gctcacagag cagatgaaat gcctggacca
181 gcagtgtgag cttcgggtgc aactgttgca ggacctccag gacttcttcc gaaagaaggc
241 agagattgag atggactact cccgcaacct ggagaagctg gcagaacgct tcctggccaa
301 gacacgcagc accaaggacc agcaattcaa gaaggatcag aatgttctct ctccagtcaa
361 ctgctggaat ctcctcttaa accaggtgaa gcgggaaagc agggaccata ccaccctgag
421 tgacatctac ctgaataata tcattcctcg atttgtacaa gtcagcgagg actcaggaag
481 actctttaaa aagagtaaag aagtcggcca gcagctccaa gatgatttga tgaaggtcct
541 gaacgagctc tactcggtga tgaagacata tcacatgtac aatgccgaca gcatcagtgc
601 tcagagcaaa ctaaaggagg cggagaagca ggaggagaag caaattggta aatcggtaaa
661 gcaggaggac cggcagaccc cacgctcccc tgactccacg gccaacgttc gcattgagga
721 gaaacatgtc cggaggagct cagtgaagaa gattgagaag atgaaggaga agcgtcaagc
781 caagtacacg gagaataagc tgaaggccat caaagcccgg aatgagtact tgctggcttt
841 ggaggcaacc aatgcatctg tcttcaagta ctacatccat gacctatctg accttattga
901 ttgttgtgac ttaggctacc atgcaagtct gaaccgggct ctacgcacct tcctctctgc
961 tgagttaaac ctggaacagt cgaagcatga gggtctggat gccatcgaga atgcagtaga
1021 aaacctggat gccaccagtg acaagcagcg cctcatggag atgtacaaca acgtcttctg
1081 cccccctatg aagtttgagt ttcagcccca catgggggat atggcttccc agctctgtgc
1141 ccagcagcct gtccagagtg agctggtaca gagatgccaa caactgcagt ctcgcttatc
1201 cactctaaag attgaaaacg aagaggtaaa gaagacaatg gaggccaccc tgcaaaccat
1261 ccaggacatt gtgactgtcg aggactttga tgtgtctgac tgcttccagt acagcaactc
1321 catggagtcc gtcaagtcca cggtctctga aaccttcatg agcaagccca gcattgctaa
1381 gaggagagcc aaccagcaag agacagagca gttttatttc acaaaaatga aagagtacct
1441 ggagggcagg aacctcatca ccaagttaca agccaagcat gaccttctgc agaaaaccct
1501 gggagaaagt cagcggacag attgcagtct agccaggcgc agctcaactg tgaggaaaca
1561 ggactccagc caggcaattc ctctagtggt ggaaagctgt atccggttta tcagcagaca
1621 cggactacag catgaaggaa ttttccgggt gtcaggatcc caggtggaag tgaatgacat
1681 caaaaatgcc tttgagagag gagaggaccc cctggctggg gaccagaacg accatgacat
1741 ggattccata gctggtgtcc tgaagcttta cttccggggg ctggaacacc ctctcttccc
1801 caaggacatc tttcatgacc tgatggcctg cgtcacaatg gacaacctgc aggagagagc
1861 tctgcacatc cggaaagtcc tcctagtcct gcccaaaacc actctgatta tcatgagata
1921 cctctttgcc ttcctcaatc atttatcaca gttcagtgaa gagaacatga tggaccccta
1981 caacctcgcc atctgcttcg ggccctcgct aatgtcagtg ccagagggcc acgaccaggt
2041 gtcctgccaa gcccacgtga atgagctgat caaaaccatc atcatccagc atgagaacat
2101 cttcccaagc cccagggagc tggagggccc tgtctacagc agaggaggaa gcatggagga
2161 ttactgtgat agccctcatg gagagactac ctcggttgaa gactcaaccc aggatgtgac
2221 cgcagagcac cacacgagcg atgacgaatg tgagcccatc gaggccattg ccaagtttga
2281 ctacgtgggc cggacagccc gagagctgtc ctttaagaag ggagcatccc tgctgcttta
2341 ccagcgggct tccgacgact ggtgggaagg ccggcacaat ggcatcgacg gactcatccc
2401 ccatcagtac atcgtggtcc aagacaccga ggacggtgtc gtggagaggt ccagccccaa
2461 gtctgagatt gaggtcattt ctgagccacc tgaagaaaag gtgacagcca gagcgggggc
2521 cagctgtccc agtgggggtc atgtagccga tatttatctt gcaaacatca acaagcaaag
2581 gaagcgtcca gaatctggga gcatccggaa aacttttcgg agtgacagcc atgggctgag
2641 cagttccctg actgactcct cctccccagg ggtgggggct agctgccgcc catcctccca
2701 gcccatcatg agccagagcc tccccaaaga agggccagat aagtgttcca tcagtgggca
2761 cgggagcctc aactccatca gccgccactc atccctgaag aatcggctgg atagtccaca
2821 gatccggaag actgccacag cgggaaggtc aaaaagcttc aataaccatc ggcccatgga
2881 ccctgaggtc attgctcagg atattgaggc aacaatgaac tcggccctga atgagctacg
2941 ggaactagaa cggcagagca gtgtcaaaca cacccctgac gtggttctgg acaccttgga
3001 gcccctcaaa acctccccag tggtggcccc cacgtcagag ccctccagcc ctctgcacac
3061 ccagctcctc aaggaccccg agcccgcctt ccagcgcagc gccagtactg ctggggacat
3121 cgcctgcgcc ttccggcctg tcaagtctgt caagatggct gccccggtca aaccaccagc
3181 cacacggccc aagcccactg tcttccccaa aacaaatgcc actagccctg gtgtcaactc
3241 atcaacttcc ccacagtcta ctgacaagtc ttgtactgtc tgagggataa taatttaatt
3301 gttctagaca aggggactat agggactgac tgttattaaa atcttcctat ttaactagct
3361 tggggacttc agttgaaaat taggttctaa gttgttcttg caggaattag cctccccgtc
3421 tcccaaaacc ttgagaatga agcccttggt atcgcctctc ccttcccact gccctctgct
3481 tcccccagtc gtcgtaattc agccagctgc agtccgtacc gttcttaggt tagccagaga
3541 caggttttca ttatcaggtc actgtgaaat ctggtaaggc agtcctgagg acatgggctc
3601 aagtctcagt cccctcagac cacggtgatg ccttgaccag atggttggct actgccatcc
3661 agctttcagt ggcatcttgt tttgggaact gattatagag aatcatatat agtccagtct
3721 tcattttaca tacacacaca tattttacac acacacacat tttacacaca cacacacaca
3781 cacacatatg tttttctagt ctctggcatg tgtagcctct cctggtcata gaccagtctc
3841 tttgtaagtt attgtggcag ttcacacagt agccaccagg ggtctctgtt tccattacaa
3901 actttgttct gtctgggcca gagaacctag cctttgaaat ctctccatca tatgaaacat
3961 aacgggatgg gacaatcccg taacctgttt ggggttgggg gctttctctc cgtgttcttt
4021 ccattgatgt gaattggtca ttggtgtttg ctcttgcctc tcctccatcc cctagaagta
4081 cacccccgtc ttattaagga gcttttaaag tttttctgaa tgtatagaca tttctcgggt
4141 tcctaccttt gtctctgatg gaccattttc catttaagac attttcctgt ataagacagt
4201 tttatagctg gttcctttta gggtaaagag tcttaagaga gttttattgt gtctatggca
4261 ggtttgggaa aggtaagaaa tgggtccttt ttcctcctaa tgtttttggc acttaaaaca
4321 taaaattcat tatcctatta aaaaattaaa ttcagctttg ctaatccaga aattgttccc
4381 aaatgaaaac ttgttttaag tccacccctt agtttcctta ttttacaagg tctctcttca
4441 gggaccaaca ggggcttaga gagccttagt tagattaaag ggagacccta cctcttaaaa
4501 ccagttttca tttatgcaaa caaggacaat taagggaacc ctgaccccac aggctctcaa
4561 gtcttcccaa ggccagaatc gaaagaaaat taaaatttga atgctgaata ttctggctct
4621 actctggcct tttttctggt tcccttccaa aatgcacaaa tcataccctt gtctgctcca
4681 attcagtctc caaacctggt gcctgtg
//