LOCUS BC144320 6378 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens coiled-coil domain containing 88A, mRNA (cDNA clone
MGC:177857 IMAGE:9052840), complete cds.
ACCESSION BC144320
VERSION BC144320.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6378)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6378)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: B Column: 2.
FEATURES Location/Qualifiers
source 1..6378
/db_xref="H-InvDB:HIT000502742"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177857 IMAGE:9052840"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: ACCTATCT"
gene 1..6378
/gene="CCDC88A"
/gene_synonym="APE"
/gene_synonym="GIRDIN"
/gene_synonym="GIV"
/gene_synonym="GRDN"
/gene_synonym="HkRP1"
/db_xref="GeneID:55704"
/db_xref="HGNC:HGNC:25523"
/db_xref="MIM:609736"
CDS 198..5588
/gene="CCDC88A"
/gene_synonym="APE"
/gene_synonym="GIRDIN"
/gene_synonym="GIV"
/gene_synonym="GRDN"
/gene_synonym="HkRP1"
/codon_start=1
/product="CCDC88A protein"
/protein_id="AAI44321.1"
/db_xref="GeneID:55704"
/db_xref="HGNC:HGNC:25523"
/db_xref="MIM:609736"
/translation="MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVD
GVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSL
PNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHI
QEVTHNQENVFDLQWMEVTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEER
DGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLD
CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKE
RLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLH
DMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSL
GHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVE
ILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQT
VSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG
ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF
KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG
LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK
NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN
VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE
KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKE
EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWE
RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ
TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE
DLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL
LKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEV
LQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE
EENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD
QYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQ
DSQDSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDL
VQSMVLAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQL
VNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGA
VNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHH
KIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPV
SCGLASVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESR
NSKSRSREQQSS"
BASE COUNT 2413 a 1085 c 1293 g 1587 t
ORIGIN
1 gccacttctt gggatttcgg ctcgtttcac tctggggtgt tttttgagga gggagagtgc
61 ccccctcctc cacgatggga tttttctccc ttgccgaaat ggactttcat tgatttctac
121 ttacttccac gtttagtgac caattcccta ggcgtatttt tgtggtagtt ccttttttca
181 aatacatact ctgtaaaatg gagaacgaaa tttttactcc ccttctggag cagttcatga
241 ccagcccttt ggtcacttgg gttaaaacgt ttggacctct ggccgcagga aatgggacca
301 accttgatga atatgtggct ttggtggatg gggtattctt gaaccaggtc atgctccaaa
361 ttaatcctaa attggagagt cagagagtaa ataaaaaagt caataatgat gcctcactta
421 gaatgcacaa tctatccatt ttggtgagac agataaaatt ttattaccag gagactttgc
481 agcaattgat catgatgtcg ttgccaaatg tcttaatcat tggcaaaaat cccttttctg
541 aacaaggcac agaagaagtt aaaaaactgc ttttactttt attgggttgt gcagttcagt
601 gtcagaaaaa agaggaattt attgaaagaa ttcaaggttt agattttgat acaaaagcag
661 cggttgccgc acatattcaa gaggtaactc ataatcagga aaatgtgttt gacctgcaat
721 ggatggaagt gactgatatg tcgcaggagg acatagaacc actcttgaaa aatatggcat
781 tgcatctaaa aagacttata gatgagagag atgaacattc agagactatc atagaactct
841 ctgaagagcg ggatggtctc cattttctac cccatgcctc ttcatctgca cagtcaccct
901 gtggttctcc aggcatgaag cgaacagaaa gtcgacaaca tctgtcggtg gaactggcag
961 atgctaaagc caagataaga aggcttaggc aggaattgga ggaaaagact gagcagttgt
1021 tggattgtaa acaagaactt gagcaaatgg aaatagaact caaaaggctg caacaagaga
1081 acatgaattt gctttcggat gctcgctctg ccagaatgta ccgagatgaa ttagatgcac
1141 ttcgagagaa agcagtcaga gtcgataagc ttgaaagtga agtcagcaga tataaagaga
1201 gactacatga tattgaattt tataaggcaa gagttgagga attaaaagaa gacaatcaag
1261 ttttattaga aacaaaaacc atgttggaag accaactaga gggaactcgt gctcgttctg
1321 ataaattaca tgaattagaa aaagagaact tacaactgaa agctaaactt catgatatgg
1381 aaatggaacg agatatggat agaaaaaaga ttgaagaatt aatggaagaa aatatgactt
1441 tggaaatggc acagaaacaa agtatggatg aatcattaca tcttggctgg gaactggaac
1501 agatatccag aactagtgaa ctttccgaag caccccagaa atccctgggc catgaggtga
1561 atgagttgac atcaagtaga ttattgaagc tagagatgga aaatcaaagt ttgacaaaaa
1621 ccgtagaaga gcttcggact actgtggatt ctgtagaagg caatgcttcc aaaatcctga
1681 aaatggaaaa agaaaatcaa aggctcagta aaaaggttga gattcttgaa aatgagattg
1741 ttcaagaaaa gcaaagtctt cagaattgtc agaatttaag caaggatcta atgaaggaga
1801 aagctcagct tgaaaaaaca atagaaacac tgagagaaaa ttcagagaga cagattaaga
1861 tactggaaca ggaaaatgaa catctgaatc aaacagtgtc ttccttaagg cagcggtccc
1921 agataagtgc agaagcaaga gtgaaagaca ttgaaaaaga aaacaaaatt cttcatgaat
1981 ctatcaaaga aacaagtagc aagctaagca agattgaatt tgaaaaaaga caaattaaaa
2041 aagaattgga acattataaa gaaaaaggag aacgagctga agaacttgaa aatgaattgc
2101 atcatcttga aaaagaaaat gaattattac agaaaaaaat aactaattta aaaattactt
2161 gtgaaaaaat tgaggcctta gaacaagaaa attcagagct agaaagagaa aatagaaaat
2221 taaaaaaaac attggatagc tttaaaaatc tgacctttca gttagaatcc ctagaaaaag
2281 agaattccca acttgatgag gaaaacttag aactgcgaag gaatgtagaa tctttgaagt
2341 gtgcaagcat gaaaatggct cagctacagc tagaaaacaa agaactggaa agtgaaaaag
2401 agcaacttaa gaagggtttg gagctcctga aagcatcttt caagaaaaca gaacgcttag
2461 aagttagcta ccagggttta gatatagaaa atcaaagact gcaaaaaact ttagagaaca
2521 gcaataaaaa aatccagcaa ttagagagtg aactacaaga cttagagatg gaaaatcaaa
2581 cattgcagaa aaacctagaa gaactaaaaa tatctagcaa aagactagaa cagctggaaa
2641 aagaaaataa atcattagag caagagactt ctcaactgga aaaggataag aaacaattgg
2701 agaaggaaaa taagagactc cgacaacaag cagaaattaa agataccaca ttagaagaaa
2761 ataatgtgaa gattggaaat ttggaaaaag aaaacaaaac cctatccaaa gaaattggta
2821 tatataaaga atcttgtgtc cgtctgaaag aactagaaaa agaaaataag gagcttgtga
2881 aaagagcaac tattgatata aaaacgttgg ttacactacg tgaggatttg gtgagtgaaa
2941 agttgaagac ccaacagatg aacaatgatc tcgaaaaatt aactcatgag cttgagaaga
3001 tagggttaaa taaggagcga ctcttacatg atgaacaaag tactgatgac aggtataaac
3061 ttttggaatc aaaattagaa tccactctta agaagtctct tgaaataaaa gaagaaaaaa
3121 ttgctgcttt agaagctcga ttagaagaat ccacgaatta taaccagcaa ttgcgccaag
3181 aacttaaaac agtgaaaaaa aattatgaag ctctcaaaca gagacaagat gaggaaagga
3241 tggtacagag ctctcctcca atatctggtg aagacaacaa atgggagcga gaaagtcaag
3301 aaacgactag agaacttctg aaagttaaag acagattaat tgaagtagaa agaaataatg
3361 ctacactgca agcagagaag caagcgttga aaactcaact gaagcaactt gagacacaga
3421 acaataattt gcaggctcag attcttgcac ttcagaggca gacagtgtca ttacaagaac
3481 agaataccac tcttcaaaca cagaatgcca agcttcaggt tgaaaattcc acccttaatt
3541 cccaaagtac ctcactcatg aaccagaatg cccaactcct aatccagcag tcttccttag
3601 aaaatgaaaa tgaatctgta atcaaagagc gagaagacct aaaatctctc tatgattctc
3661 tgatcaaaga tcatgaaaag ctggaacttc ttcatgaacg tcaggcttca gagtatgaat
3721 ctcttatctc taaacatgga actctgaagt ctgcccacaa aaatcttgag gtggaacata
3781 gagaccttga agaccgttac aatcagttat taaaacagaa aggacagttg gaagatttgg
3841 aaaaaatgct caaagtagaa caggaaaaaa tgctgcttga aaataaaaat catgaaacag
3901 tagctgcaga atacaagaaa ctttgtggtg aaaatgatag gctgaatcat acctatagtc
3961 aacttttaaa agagactgaa gttttacaaa ctgaccataa aaatttgaaa agtcttctga
4021 ataattccaa actggaacaa acaagattag aagctgaatt ttcaaaacta aaggaacaat
4081 accaacaatt ggatattaca tcaaccaagc tgaataacca gtgtgagttg ctaagccaac
4141 ttaaaggaaa tttagaagaa gaaaatcggc atctactaga tcaaattcag acattaatgc
4201 tacagaacag aacacttttg gagcagaata tggaaagcaa ggatcttttt catgttgaac
4261 aaagacagta cattgataag ttaaatgaat taagacgtca gaaggagaaa ctagaagaga
4321 aaattatgga tcaatacaaa ttttatgacc catctcctcc tagaaggaga ggcaactgga
4381 ttactctaaa aatgagaaaa ttgataaagt ctaagaaaga tattaatcgg gaacgccaga
4441 aatctctaac attaacaccc acccgctcag actccagtga aggatttctt cagctccctc
4501 atcaagacag tcaagatagt tcttcagtag gttcaaactc tttagaagat ggccagacct
4561 tggggaccaa gaaaagcagc atggttgcac tgaaaagact gccctttttg aggaacagac
4621 cgaaggataa agacaaaatg aaggcctgct accgtcgttc catgtccatg aatgacctgg
4681 tgcagtccat ggtcctagca ggacagtgga caggtagtac tgagaatttg gaggttcctg
4741 atgatatttc aacgggtaaa aggagaaaag aattgggagc tatggccttc tctactacag
4801 ccatcaactt ttcaactgtc aactcttctg caggcttcag atccaagcag ttggttaata
4861 ataaagatac tacatccttt gaagacataa gtccacaagg tgttagtgat gattctagta
4921 cgggatcaag agttcatgct tcaagaccag ccagccttga tagtggcaga acatccacta
4981 gcaatagcaa taataatgct tcactacatg aagtcaaagc aggtgcagtt aataaccaaa
5041 gcaggccaca aagccacagc agtggagaat ttagcctgct tcatgaccat gaggcttggt
5101 ccagcagtgg tagcagtcca atccagtact tgaaaagaca gaccagatca agcccagtgc
5161 tccagcacaa aatatctgaa acactggaga gtcgacatca caagatcaaa actggttccc
5221 ctggaagtga agttgttact ctacaacagt ttttggaaga aagcaataag cttacctcag
5281 tacagataaa gtcctcaagt caagagaatc ttttagatga agtaatgaaa agtttgtctg
5341 tctcttctga ctttttggga aaagacaaac cagttagctg tggtctggcc agcgtgatct
5401 caactgccga aggaactaca cgaaggacaa gcatccatga ttttttgacc aaggacagta
5461 gactgcctat atcagttgat tcaccaccag ctgctgctga cagcaacacc actgcagcat
5521 ctaatgtgga caaagtacaa gaaagcagaa attcaaaaag caggtctagg gagcaacaaa
5581 gctcctaatt ctattaccca ctacatgaca tgtgggccaa gtgagagaaa agtgtccttc
5641 agtttctcag tatgaagcct ttatttctga agtaacaaga cacctagcaa ctataggaat
5701 catttttaaa aatctttaag gagactttta acagtccttc gtgaatagag caggcaagaa
5761 atacaaacct tcattccttg aatcaaggag cactactgga ttcaactgcc aaaatttttt
5821 aaaggtttta ggacttacta taccttgtac tgttaagatc tactgaataa aggacgttct
5881 ctcactaagg accaggtgtt ttaaggttaa gtgtttaaag aagtactcca agaacaatct
5941 gcttttttca tcatttgttt tatgaattta tccatgtttg cttaatgctt ctgctaagtg
6001 ttagccaaaa tctagccatt tatatttagt tgtgtaaacc taaattaaat gctgtagtat
6061 tttgtggaat gtactatata gcaagataca gagaaaattg ttttggcatg tcagagcctt
6121 atttggttag cagactgcat gtgttgatac tttttttttc ttaaagccaa ttattttgat
6181 gcaaaagaaa ttcagtttat aagataaatc tgaaaaatcc ataatgaaat aggagttata
6241 aaaaatttat agtgatatta atctttccat atttcccatt aagcaacact aagcattcat
6301 aagttaaccc atggtaaaga gtgtttttct gaaacttttt tttagtaaga tggtttttca
6361 gcaaatggca ttcccaag
//