LOCUS BC144300 5106 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens FYVE, RhoGEF and PH domain containing 5, mRNA (cDNA
clone MGC:177837 IMAGE:9052820), complete cds.
ACCESSION BC144300
VERSION BC144300.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5106)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5106)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: F Column: 22.
FEATURES Location/Qualifiers
source 1..5106
/db_xref="H-InvDB:HIT000502723"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177837 IMAGE:9052820"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: TAAATTCA"
gene 1..5106
/gene="FGD5"
/gene_synonym="ZFYVE23"
/db_xref="GeneID:152273"
/db_xref="HGNC:HGNC:19117"
CDS 472..4008
/gene="FGD5"
/gene_synonym="ZFYVE23"
/codon_start=1
/product="FGD5 protein"
/protein_id="AAI44301.1"
/db_xref="GeneID:152273"
/db_xref="HGNC:HGNC:19117"
/translation="MGQDAEDTSEEPPEKEELAGVQEAETATDCPEVLEEGCEEATGV
TGGEQVDLSEPPDHEKKTNQEVAAATLEDHAQDESAEESCQIVPFENDCMEDFVTSLT
GSPYEFFPTESTSFCSESCSPLSESAKGLESEQAPKLGLRAEENPMVGALCGQCGSLQ
GGAAEGPAAPDVVVVLEEEALDDALANPYVMGVGLPGQAAPGEGGQAASDALGGYGSK
EELNCEAEGGLVPADRKNTSTRVRPHSGKVAGYVPETVPEETGPEAGSSAPGIGGAAE
EVGKTLLSLEGKPLEASRALPAKPRAFTLYPRSFSVEGREIPVSVYQEPEGSGLDDHR
IKRKEDNLSLSCVIGSSGSFSQRNHLPSSGTSTPSSMVDIPPPFDLACITKKPITKSS
PSLLIESDSPDKYKKKKSSFKRFLALTFKKKTENKLHVDVNVSSSRSSSESSYHGPSR
ILEVDRRSLSNSPQLKSRTGKLRASESPSSLIFYRDGKRKGVPFSRTVSRVESFEDRS
RPPFLPLPLTKPRSISFPSADTSDYENIPAMNSDYENIQIPPRRPARAGAFTKLFEDQ
SRALSTANENDGYVDMSSFNAFESKQQSADQDAESAYTEPYKVCPISSAAPKEDLTSD
EEQRSSEEEDSASRDPSVTHKVEGQSRALVIAQELLSSEKAYVEMLQHLNLDFHGAVM
RALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFL
AREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRV
VQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHI
EHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLYTYPQKDGKYRLKN
TLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQ
ALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIV
CRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSG
SAFSSVFQSINPSTFKKQKKVPSALTEDKVALESMPLLGFTIAPEKEEGSSEVGPIFH
LYHKKTLFYSFKAEDTNSAQRWIEAMEDASVL"
BASE COUNT 1248 a 1336 c 1470 g 1052 t
ORIGIN
1 gggaacaaag ccctggtgtc tcccgagtcc tctgcggaag aggaagagga gcgtgaagag
61 ggaggcgagg catgtggcct ggagggtaca ggagctggtg aggattcagt ggcccctgct
121 gctccgggtg caggagcgct gagcagggag ggtgaggaag gcacagacct tgctcttgag
181 gatgaagggg agggctgcgc tgatgagcca gggacactgg agcaggtgtc cagaagtgag
241 gaggaagaga agctagtgca gccacacagg gagtgcagcc tggaggacag tgggccttgg
301 gctggagagg gggtcttcca gagcgacctc ctcctgcctc acatccatgg agaggaccag
361 gagccccccg acacccccgg ggaggcagag gaggatgatg aggaaggctg tgccagcaca
421 gacccagcag gggcagatga gggttcgggt cctgacaggc ccacggagga catgggacag
481 gatgctgagg acaccagtga ggagccccct gagaaggagg agctggccgg ggtccaggag
541 gcagagacag ccacagactg ccctgaagtt cttgaggagg gatgtgaaga ggccacgggt
601 gtcacaggtg gggaacaggt tgacctcagt gaaccacctg accacgagaa gaaaaccaac
661 caagaagtgg cagccgccac cctggaggac catgcacagg atgagtccgc cgaggagagc
721 tgccagattg tcccttttga gaatgactgc atggaggact tcgtgacttc cctcacagga
781 agcccctatg agttcttccc aactgagagc acctcttttt gcagcgagag ctgttctcct
841 ctttctgaat cagcgaaagg tttagaatca gagcaggcac caaagctggg gctgcgtgcg
901 gaggagaacc ccatggtggg ggctttgtgt ggccagtgtg gctccctaca gggtggagcg
961 gccgagggtc ccgcagcccc tgatgtggtg gtcgtgctgg aggaggaggc cttggatgat
1021 gcactggcca acccctatgt gatgggagtg ggcctgcccg gtcaggcggc ccctggagaa
1081 ggagggcagg ctgcatcgga cgccctgggt ggttatggct cgaaagaaga attgaactgt
1141 gaggcagagg gtggcctggt tcccgcggac aggaagaaca ccagcacgag ggtccggccc
1201 cactctggga aggtggccgg ctatgtccca gaaaccgtcc ctgaagaaac cggacctgag
1261 gcgggctcgt cagcccctgg cattggaggt gccgcagagg aggtgggaaa gacgcttttg
1321 tcattggagg ggaagccctt ggaagccagc agggccttgc cagcaaagcc cagggccttt
1381 actttatacc ctcggtcgtt ctccgtggaa ggccgagaga ttccagtgtc cgtgtaccag
1441 gagcctgagg ggtcagggtt ggatgaccac aggataaaga ggaaagagga caatctctct
1501 ctgtcgtgtg taattggctc ctctgggagt ttctcccaga gaaaccacct tccgtccagc
1561 ggcacctcca cgccttcttc catggtcgac atcccacctc ctttcgacct ggcctgcatc
1621 accaagaagc ccatcacaaa gagctctccc tcactcctga tcgagagcga ctccccggac
1681 aagtacaaga agaagaagtc atcctttaag cgcttcctgg cactgacgtt taagaagaag
1741 acggagaaca aattgcatgt ggatgtgaac gtgtcttcct ctaggtcctc ttcagagtcc
1801 agctaccacg ggccttccag gattctggaa gttgaccgga gaagcctcag caactcccct
1861 cagcttaagt ctcggactgg gaagctccgg gcttctgaat ccccctcctc cctcatcttt
1921 tatagagatg gcaagaggaa aggtgtcccc ttcagcagga cggtgtccag agtggagtcc
1981 tttgaagacc gctcccggcc gcccttcctg cccttgccac tgaccaagcc acggtccatc
2041 tccttcccca gcgctgacac ttcagactat gagaacattc cagccatgaa ctcggactat
2101 gagaatatcc agattccacc ccggagacct gccagggctg gcgcgttcac gaagctgttt
2161 gaagatcaga gcagagccct gtccacagca aacgaaaatg atggctacgt ggacatgagc
2221 agcttcaacg cctttgagag caaacagcag agtgcagacc aggacgcaga aagcgcctac
2281 acagagccct acaaagtctg tcccatctcg tcggcagccc ccaaagagga ccttacgtcg
2341 gatgaagagc agagaagctc ggaggaggag gacagtgctt caagagaccc cagtgtcacc
2401 cacaaggtgg aaggacagtc cagagccctt gtcatcgcac aggaactgct atcttcagag
2461 aaagcatacg tggagatgct ccagcactta aatctggatt tccatggagc tgtcatgagg
2521 gccttggatg acatggacca tgaaggcaga gacacattgg cccgggagga gctgaggcag
2581 ggcctgagtg aactcccagc catccacgac cttcatcaag gcatcctgga ggagctggag
2641 gaaaggctgt caaattggga gagccagcag aaggtagctg acgtcttcct ggcccgggag
2701 caggggtttg atcaccacgc cactcacatc ctgcagttcg acaggtacct aggtctgctc
2761 agtgagaatt gcctccactc tccccggctg gcagctgctg tccgtgaatt tgagcagagt
2821 gtacaaggag gcagccagac tgcgaagcat cggctgctgc gggtggttca acgcctcttc
2881 cagtaccaag tgctcctcac agactattta aacaaccttt gtccggactc cgccgagtac
2941 gacaacacac agggtgcact gagcctcatc tccaaagtca cagaccgtgc caacgacagc
3001 atggagcaag gggaaaacct gcagaagctg gtccacattg agcacagcgt ccggggccaa
3061 ggggatctcc tccagccagg aagggagttt ctgaaggaag ggacgctgat gaaagtaaca
3121 gggaaaaaca gacggccccg gcacctattt ctgatgaacg atgtgctcct gtacacctat
3181 ccccagaagg atgggaagta ccggctgaag aacacattgg ctgtggccaa catgaaggtc
3241 agccgccctg tgatggagaa agtgccctac gctctaaaga ttgagacttc cgagtcctgc
3301 ctgatgctgt ctgcgagctc ctgtgcagag agggacgagt ggtatggctg tctgagcaga
3361 gccctccctg aggactacaa ggcccaggcg ctggctgcat tccaccatag cgtggagata
3421 cgagagaggc tgggggttag ccttggggag aggcccccca ccctggtgcc tgtcacacac
3481 gtcatgatgt gcatgaactg cggctgcgac ttctccctca ccctgcggcg tcatcactgt
3541 cacgcctgtg gcaagatcgt gtgccggaac tgttcgcgga acaagtaccc gctgaagtac
3601 ctgaaggaca ggatggccaa ggtctgcgac ggctgcttcg gggagctgaa gaagcggggc
3661 agggctgtcc cgggcctgat gagagagcgg cctgtgagca tgagcttccc gctgtcttca
3721 ccccgcttct cgggcagtgc cttttcatcc gtcttccaga gcattaaccc ctcgaccttc
3781 aagaagcaga agaaagtccc ttcagccctg acagaggaca aagtggcctt ggagagtatg
3841 cctctgctag gcttcaccat tgctccagaa aaggaagagg gcagcagtga agtaggacct
3901 atttttcacc tttaccacaa gaaaacccta ttttatagct tcaaagcaga agataccaat
3961 tcagctcaga ggtggatcga ggccatggaa gatgcgagtg tgttatagca gttatcaagc
4021 atgtggactt gtaacaaatt cttaggtcaa tatgtgaatg cttttagaag ctaagctgtg
4081 gctcaactca tccggacaca cacctggatt cagcaatgag gcctgacctt ttttgctata
4141 accgccccac cactcccctg cccttgccaa catcttcatg aatggaatcc ttaagggata
4201 tttatggacc tctccttttc tgtgttttcc acccctaccc ccacccgcca cccagtaata
4261 aactatttcc ttaccccgca gtgagttaaa atttagtaag atgaagatgt ggaaaccaat
4321 gaaaagtaca tttagaaatg caggcttttt agtagaaaga agctcttaca gtttttactc
4381 atgataaatc ttatcacctt tcaaaaattg attgtggtgc ctcaggtgaa atgagaagct
4441 atcagtaaca gctactctca tcgaaagcac tttattattt tacggagctg caacctccaa
4501 ttttgtgttt tctaagtgat ttacttaagt caataacaga tggaatcctg tggactaatg
4561 tgccaccagt tttctaacaa gggtgtacat aaaatggatt tgtgcagacc tggctgtggc
4621 ttgctggtgt gcaagcacac atcactttag aggggctgcg ccccaccaga taggaagggg
4681 aggattttct cctccagtcg accttgtgac ctgtatacta acataactta ttaaaggagg
4741 ggtccctcct cccccagagc agtcctcaac actgtcagtg ctggaaatgc agccactggc
4801 agatctggcc ccccagacgt caccgcaggg cctctgaaga gtcaaggtct gctttaattt
4861 attgtgtgcc tttctgtgtt tacctcactc aagctgacaa cattgtttat gggaatctat
4921 ccttctttta gacacacggt aatccttggg ctgtattact gaaggctttt tattttttga
4981 gaggtgaaaa aaagagaaaa caagttagac tccaaaggtg aattcctggt cttggcagat
5041 ggctctggga acagcgaggg agcacagaag tcgtggcctg aggctgttct atgggcactt
5101 ggggct
//