LOCUS BC144184 1786 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens nuclear receptor subfamily 1, group H, member 4, mRNA
(cDNA clone MGC:177721 IMAGE:9052704), complete cds.
ACCESSION BC144184
VERSION BC144184.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1786)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1786)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: F Column: 5.
FEATURES Location/Qualifiers
source 1..1786
/db_xref="H-InvDB:HIT000502613"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177721 IMAGE:9052704"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_361"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: AATGTGCA"
gene 1..1786
/gene="NR1H4"
/gene_synonym="BAR"
/gene_synonym="FXR"
/gene_synonym="HRR-1"
/gene_synonym="HRR1"
/gene_synonym="RIP14"
/db_xref="GeneID:9971"
/db_xref="HGNC:HGNC:7967"
/db_xref="MIM:603826"
CDS 334..1764
/gene="NR1H4"
/gene_synonym="BAR"
/gene_synonym="FXR"
/gene_synonym="HRR-1"
/gene_synonym="HRR1"
/gene_synonym="RIP14"
/codon_start=1
/product="NR1H4 protein"
/protein_id="AAI44185.1"
/db_xref="GeneID:9971"
/db_xref="HGNC:HGNC:7967"
/db_xref="MIM:603826"
/translation="MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVE
PYSQYSNVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETE
VAEMPVTKKPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAV
YKCKNGGNCVMDMYMRRKCQECRLRKCREMGMLAECMYTGLLTEIQCKSKRLRKNVKQ
HADQTVNEDSEGRDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNK
ILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFL
RSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAI
VILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHH
HAEMLMSWRVNDHKFTPLLCEIWDVQ"
BASE COUNT 566 a 349 c 411 g 460 t
ORIGIN
1 tcacctcatt gtctccccga cttatcctaa tgcgaaattg gattctgagc atttgtagca
61 aaatcgctgg gatctggaga ggaagactca gtccagaatc ctcccagggc cttgaaagtc
121 catctctgac ccaaaacaat ccaaggaggt agaagacatc gtagaaggag tgaaagaaga
181 aaagaagact tagaaacata gctcaaagtg aacactgctt ctcttagttt cctggatttc
241 ttctggacat ttcctcaaga tgaaacttca gacactttgg agtttttttt gaagaccacc
301 ataaagaaag tgcatttcaa ttgaaaaatt tggatgggat caaaaatgaa tctcattgaa
361 cattcccatt tacctaccac agatgaattt tctttttctg aaaatttatt tggtgtttta
421 acagaacaag tggcaggtcc tctgggacag aacctggaag tggaaccata ctcgcaatac
481 agcaatgttc agtttcccca agttcaacca cagatttcct cgtcatccta ttattccaac
541 ctgggtttct acccccagca gcctgaagag tggtactctc ctggaatata tgaactcagg
601 cgtatgccag ctgagactct ctaccaggga gaaactgagg tagcagagat gcctgtaaca
661 aagaagcccc gcatgggcgc gtcagcaggg aggatcaaag gggatgagct gtgtgttgtt
721 tgtggagaca gagcctctgg ataccactat aatgcactga cctgtgaggg gtgtaaaggt
781 ttcttcagga gaagcattac caaaaacgct gtgtacaagt gtaaaaacgg gggcaactgt
841 gtgatggata tgtacatgcg aagaaagtgt caagagtgtc gactaaggaa atgcagagag
901 atgggaatgt tggctgaatg tatgtataca ggcttgttaa ctgaaattca gtgtaaatct
961 aagcgactga gaaaaaatgt gaagcagcat gcagatcaga ccgtgaatga agacagtgaa
1021 ggtcgtgact tgcgacaagt gacctcgaca acaaagtcat gcagggagaa aactgaactc
1081 accccagatc aacagactct tctacatttt attatggatt catataacaa acagaggatg
1141 cctcaggaaa taacaaataa aattttaaaa gaagaattca gtgcagaaga aaattttctc
1201 attttgacgg aaatggcaac caatcatgta caggttcttg tagaattcac aaaaaagcta
1261 ccaggatttc agactttgga ccatgaagac cagattgctt tgctgaaagg gtctgcggtt
1321 gaagctatgt tccttcgttc agctgagatt ttcaataaga aacttccgtc tgggcattct
1381 gacctattgg aagaaagaat tcgaaatagt ggtatctctg atgaatatat aacacctatg
1441 tttagttttt ataaaagtat tggggaactg aaaatgactc aagaggagta tgctctgctt
1501 acagcaattg ttatcctgtc tccagataga caatacataa aggatagaga ggcagtagag
1561 aagcttcagg agccacttct tgatgtgcta caaaagttgt gtaagattca ccagcctgaa
1621 aatcctcaac actttgcctg tctcctgggt cgcctgactg aattacggac attcaatcat
1681 caccacgctg agatgctgat gtcatggaga gtaaacgacc acaagtttac cccacttctc
1741 tgtgaaatct gggacgtgca gtgatgggga ttacagggga ggggtc
//