LOCUS BC144163 3954 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens structural maintenance of chromosomes 2, mRNA (cDNA
clone MGC:177700 IMAGE:9052683), complete cds.
ACCESSION BC144163
VERSION BC144163.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3954)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3954)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: K Column: 12.
FEATURES Location/Qualifiers
source 1..3954
/db_xref="H-InvDB:HIT000502593"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177700 IMAGE:9052683"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TACGTCCC"
gene 1..3954
/gene="SMC2"
/gene_synonym="CAP-E"
/gene_synonym="CAPE"
/gene_synonym="hCAP-E"
/db_xref="GeneID:10592"
/db_xref="HGNC:HGNC:14011"
/db_xref="MIM:605576"
CDS 151..3744
/gene="SMC2"
/gene_synonym="CAP-E"
/gene_synonym="CAPE"
/gene_synonym="hCAP-E"
/codon_start=1
/product="SMC2 protein"
/protein_id="AAI44164.1"
/db_xref="GeneID:10592"
/db_xref="HGNC:HGNC:14011"
/db_xref="MIM:605576"
/translation="MHIKSIILEGFKSYAQRTEVNGFDPLFNAITGLNGSGKSNILDS
ICFLLGISNLSQVRASNLQDLVYKNGQAGITKASVSITFDNSDKKQSPLGFEVHDEIT
VTRQVVIGGRNKYLINGVNANNTRVQDLFFSVGLNVNNPHFLIMQGRITKVLNMKPPE
ILSMIEEAAGTRMYEYKKIAAQKTIEKKEAKLKEIKTILEEEITPTIQKLKEERSSYL
EYQKVMREIEHLSRLYIAYQFLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKA
LNHEIEELEKRKDKETGGILRSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKEL
EKNMVEDSKTLAAKEKEVKKITDGLHALQEASNKDAEALAAAQQHFNAVSAGLSSNED
GAEATLAGQMMACKNDISKAQTEAKQAQMKLKHAQQELKNKQAEVKKMDSGYRKDQEA
LEAVKRLKEKLEAEMKKLNYEENKEESLLEKRRQLSRDIGRLKETYEALLARFPNLRF
AYKDPEKNWNRNCVKGLVASLISVKDTSATTALELVAGERLYNVVVDTEVTGKKLLER
GELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVEYKPELQKAMEFVF
GTTFVCDNMDNAKKVAFDKRIMTRTVTLGGDVFDPHGTLSGGARSQAASILTKFQELK
DVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHK
QQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKL
DCAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEV
MAAEVAKNKESVNKAQEEVTKQKEVITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELD
HNISKHKREAEDGAAKVSKMLKDYDWINAERHLFGQPNSAYDFKTNNPKEAGQRLQKL
QEMKEKLGRNVNMRAMNVLTEAEERYNDLMKKKRIVENDKSKILTTIEDLDQKKNQAL
NIAWQKVNKDFGSIFSTLLPGANAMLAPPEGQTVLDGLEFKVALGNTWKENLTELSGG
QRSLVALSLILSMLLFKPAPIYILDEVDAALDLSHTQNIGQMLRTHFTHSQFIVVSLK
EGMFNNANVLFKTKFVDGVSTVARFTQCQNGKISKEAKSKAKPPKGAHVEV"
BASE COUNT 1435 a 671 c 857 g 991 t
ORIGIN
1 gttccctgcc tttgtgaccc ggaggagctt ttggggtgcg tcaagcccct ggcctgaggc
61 agcggtggtg gtatttctgt ttcgtacaga actggtttgt ggcctgtttg attcctgtca
121 gaggtttgct gacccaagac agtatcgaaa atgcatatta agtcaattat tctagaggga
181 ttcaagtcct atgctcagag gaccgaagtc aatggttttg accccctctt caatgctatc
241 actggcttaa atggtagtgg gaaatccaac atattggact ccatctgctt tttgctgggc
301 atctccaacc tgtctcaggt tcgggcttct aatttacaag atttagttta caaaaatggg
361 caggctggta ttaccaaagc ctctgtgtca atcacttttg ataattctga caaaaagcaa
421 agtcctttag gatttgaggt tcatgatgaa atcacagtaa caaggcaggt ggttattggt
481 ggtagaaata aatatttaat caatggagtc aatgccaaca acaccagagt acaggatctc
541 ttcttttctg ttggccttaa tgttaacaac cctcactttc tcatcatgca gggccgaatt
601 acaaaagtat tgaatatgaa acctccagag attttatcca tgatagaaga agcagctgga
661 accaggatgt atgaatacaa aaaaatagct gcacagaaaa ctatagaaaa aaaggaggct
721 aagctgaaag aaattaagac gatacttgaa gaagagatta ctccaaccat tcaaaaatta
781 aaagaggaaa gatcgtccta cttggagtac caaaaagtaa tgagagaaat agaacatttg
841 agtcgtttat atattgctta tcagtttttg ctggctgaag ataccaaagt acgctcagct
901 gaggaattaa aagaaatgca agataaagtt ataaagcttc aggaagaatt gtctgagaat
961 gataaaaaaa taaaagcact taatcatgaa atagaagaat tggaaaaaag aaaagataag
1021 gaaactggag gtatacttcg atctttagaa gatgctcttg cagaggctca gcgagttaat
1081 actaaatctc aaagcgcatt tgatctcaag aagaaaaatc tggcatgtga ggaaagcaaa
1141 cgcaaagagc tggaaaaaaa tatggttgag gactcaaaaa ctttagcagc aaaggaaaaa
1201 gaggttaaaa agataacaga tggactgcat gcccttcaag aagcaagtaa taaagatgct
1261 gaagctctgg cagctgcaca gcagcacttc aatgctgttt ccgctggcct gtccagtaat
1321 gaagatggag cagaagcaac tcttgctggt caaatgatgg cctgtaaaaa tgatataagt
1381 aaagctcaga cagaagccaa acaggctcag atgaagttga agcatgctca acaggaatta
1441 aagaataaac aagctgaagt taagaagatg gatagtggct acaggaagga tcaagaagct
1501 ctagaagctg taaaaagact taaagaaaaa cttgaagctg aaatgaaaaa gctaaattat
1561 gaagaaaata aagaggaaag ccttttggaa aagcgcaggc agctgtctcg tgatattggt
1621 agattgaaag aaacatatga agctctatta gccagatttc ccaatcttcg atttgcatac
1681 aaggatccag agaagaactg gaatagaaat tgtgtgaaag gacttgtggc ttctctgatt
1741 agtgtgaaag acacttctgc aaccacagct ttagaattag tggctggaga acgactctac
1801 aatgttgtag tagacacaga agttactggt aaaaagctac tagaaagggg ggaactgaaa
1861 cgtcgataca ctataattcc actcaataaa atttcagcca gatgtattgc accagaaact
1921 ctgagagttg ctcagaatct tgttggccct gacaacgttc atgtggctct ttccttggtt
1981 gaatataaac cagaacttca gaaagcaatg gagtttgtct ttggaacaac atttgtttgt
2041 gacaatatgg ataatgccaa aaaagtggcc tttgataaga ggataatgac tagaactgta
2101 actctcggag gtgatgtgtt tgatcctcat gggacattga gtggaggtgc tcgatcccag
2161 gcagcttcca ttttaaccaa gtttcaagaa ctcaaagatg ttcaggatga actgagaatc
2221 aaagagaatg agctgcgggc tctagaagag gaattagcag gtcttaaaaa cactgctgaa
2281 aagtatcgcc aactaaaaca gcagtgggag atgaaaactg aagaggcaga tttattacaa
2341 accaagctcc agcaaagctc atatcacaag caacaagaag aattagatgc ccttaaaaaa
2401 accattgagg aaagtgagga gactttgaaa aacactaaag aaatccaaag aaaagcagaa
2461 gaaaaatatg aagtattgga aaataaaatg aaaaatgcag aagctgaaag agagcgagaa
2521 ctgaaagatg ctcagaaaaa actggattgt gccaaaacaa aggcagatgc atctagcaag
2581 aagatgaaag aaaaacaaca ggaagttgaa gctatcactc tggaactgga agagctcaag
2641 agagagcata catcttacaa acaacagctt gaagctgtaa atgaagctat caaatcctat
2701 gaaagtcaga ttgaagtaat ggcagctgag gtggctaaaa ataaggagtc agtaaataaa
2761 gctcaagaag aggtgaccaa gcaaaaagag gtgataacag cccaagacac tgtaattaaa
2821 gctaaatatg cagaagtggc aaaacacaag gagcaaaaca atgattctca gcttaaaatt
2881 aaggaattag accacaacat cagcaaacat aaacgggagg ctgaagatgg tgctgcaaag
2941 gtatccaaaa tgttgaaaga ttatgactgg attaatgcag agagacacct ctttggccaa
3001 cccaatagtg cctatgattt caaaactaac aaccctaaag aagctggtca gagacttcag
3061 aagttgcaag aaatgaagga gaaactagga agaaatgtca atatgagagc tatgaatgta
3121 ttgacagaag ctgaagagcg atacaatgac ttgatgaaga agaagagaat tgtagaaaat
3181 gacaaatcca aaattcttac aactatagaa gaccttgacc agaagaaaaa ccaagcccta
3241 aatattgcat ggcaaaaggt gaacaaggac tttgggtcta ttttttctac tcttttgcct
3301 ggtgctaatg ctatgcttgc accaccagag ggtcaaactg ttttggatgg tctggagttc
3361 aaggttgcct taggaaatac ctggaaagaa aacctaactg aacttagtgg tggtcagagg
3421 tctttagtgg ccttgtcatt aatactgtcc atgcttctct tcaaacctgc tccaatttat
3481 atccttgatg aggtagatgc agccttggat ctttctcata cccaaaacat tggacagatg
3541 ctgcgtactc atttcacaca ttctcagttc attgtggtgt cactaaaaga aggtatgttc
3601 aacaatgcaa acgttctttt caaaaccaag tttgtggatg gtgtttctac agtagccaga
3661 tttactcaat gtcaaaatgg aaagatttca aaggaagcaa aatccaaggc aaaaccaccc
3721 aaaggagcac atgtggaagt ttaaactaca aagttatttc ttcatcttga cctgtttttt
3781 taaatgtaaa cttttaagga cttgagataa ctaatttgtt tatatacaaa aattaatgtt
3841 actgtgttac ttaacccatg ttttctcttt atataatcac ttatcgctta caaatgagca
3901 tatattcctc atctcttaac tagtctaatt atggtccaat tattgtggtt gtga
//