LOCUS BC143976 4398 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ATPase, Cu++ transporting, beta polypeptide, mRNA
(cDNA clone MGC:177511 IMAGE:9052494), complete cds.
ACCESSION BC143976
VERSION BC143976.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4398)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4398)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 16 Row: H Column: 8.
FEATURES Location/Qualifiers
source 1..4398
/db_xref="H-InvDB:HIT000502415"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177511 IMAGE:9052494"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_363"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: GCAGCCTA"
gene 1..4398
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
CDS 75..4328
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/codon_start=1
/product="ATP7B protein"
/protein_id="AAI43977.1"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
/translation="MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGY
EGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKY
VPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSS
IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS
LGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE
ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGS
GTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISV
SLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTD
GTPTSVQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIER
NLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNI
ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEE
IGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSM
VLDHNIIPGLSILNLIFFILCTFVQAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKT
SEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVL
EGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVE
EAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHIS
QTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHK
IKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKY
CKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAE
KDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAI
ADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKV
QELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVAS
IHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVL
SSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVS
QVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI"
BASE COUNT 1061 a 1146 c 1211 g 980 t
ORIGIN
1 cgctctcctc caccgaccag gtgacctttt gctctgagcc agatcagaga agaattcggt
61 gtccgtgcgg gacgatgcct gagcaggaga gacagatcac agccagagaa ggggccagtc
121 ggaaaatctt atctaagctt tctttgccta cccgtgcctg ggaaccagca atgaagaaga
181 gttttgcttt tgacaatgtt ggctatgaag gtggtctgga tggcctgggc ccttcttctc
241 aggtggccac cagcacagtc aggatcttgg gcatgacttg ccagtcatgt gtgaagtcca
301 ttgaggacag gatttccaat ttgaaaggca tcatcagcat gaaggtttcc ctggaacaag
361 gcagtgccac tgtgaaatat gtgccatcgg ttgtgtgcct gcaacaggtt tgccatcaaa
421 ttggggacat gggcttcgag gccagcattg cagaaggaaa ggcagcctcc tggccctcaa
481 ggtccttgcc tgcccaggag gctgtggtca agctccgggt ggagggcatg acctgccagt
541 cctgtgtcag ctccattgaa ggcaaggtcc ggaaactgca aggagtagtg agagtcaaag
601 tctcactcag caaccaagag gccgtcatca cttatcagcc ttatctcatt cagcccgaag
661 acctcaggga ccatgtaaat gacatgggat ttgaagctgc catcaagagc aaagtggctc
721 ccttaagcct gggaccaatt gatattgagc ggttacaaag cactaaccca aagagacctt
781 tatcttctgc taaccagaat tttaataatt ctgagacctt ggggcaccaa ggaagccatg
841 tggtcaccct ccaactgaga atagatggaa tgcattgtaa gtcttgcgtc ttgaatattg
901 aagaaaatat tggccagctc ctaggggttc aaagtattca agtgtccttg gagaacaaaa
961 ctgcccaagt aaagtatgac ccttcttgta ccagcccagt ggctctgcag agggctatcg
1021 aggcacttcc acctgggaat tttaaagttt ctcttcctga tggagccgaa gggagtggga
1081 cagatcacag gtcttccagt tctcattccc ctggctcccc accgagaaac caggtccagg
1141 gcacatgcag taccactctg attgccattg ccggcatgac ctgtgcatcc tgtgtccatt
1201 ccattgaagg catgatctcc caactggaag gggtgcagca aatatcggtg tctttggccg
1261 aagggactgc aacagttctt tataatccct ctgtaattag cccagaagaa ctcagagctg
1321 ctatagaaga catgggattt gaggcttcag tcgtttctga aagctgttct actaaccctc
1381 ttggaaacca cagtgctggg aattccatgg tgcaaactac agatggtaca cctacatctg
1441 tgcaggaagt ggctccccac actgggaggc tccctgcaaa ccatgccccg gacatcttgg
1501 caaagtcccc acaatcaacc agagcagtgg caccgcagaa gtgcttctta cagatcaaag
1561 gcatgacctg tgcatcctgt gtgtctaaca tagaaaggaa tctgcagaaa gaagctggtg
1621 ttctctccgt gttggttgcc ttgatggcag gaaaggcaga gatcaagtat gacccagagg
1681 tcatccagcc cctcgagata gctcagttca tccaggacct gggttttgag gcagcagtca
1741 tggaggacta cgcaggctcc gatggcaaca ttgagctgac aatcacaggg atgacctgcg
1801 cgtcctgtgt ccacaacata gagtccaaac tcacgaggac aaatggcatc acttatgcct
1861 ccgttgccct tgccaccagc aaagcccttg ttaagtttga cccggaaatt atcggtccac
1921 gggatattat caaaattatt gaggaaattg gctttcatgc ttccctggcc cagagaaacc
1981 ccaacgctca tcacttggac cacaagatgg aaataaagca gtggaagaag tctttcctgt
2041 gcagcctggt gtttggcatc cctgtcatgg ccttaatgat ctatatgctg atacccagca
2101 acgagcccca ccagtccatg gtcctggacc acaacatcat tccaggactg tccattctaa
2161 atctcatctt ctttatcttg tgtacctttg tccaggcgga gaggagccct gtgacattct
2221 tcgacacgcc ccccatgctc tttgtgttca ttgccctggg ccggtggctg gaacacttgg
2281 caaagagcaa aacctcagaa gccctggcta aactcatgtc tctccaagcc acagaagcca
2341 ccgttgtgac ccttggtgag gacaatttaa tcatcaggga ggagcaagtc cccatggagc
2401 tggtgcagcg gggcgatatc gtcaaggtgg tccctggggg aaagtttcca gtggatggga
2461 aagtcctgga aggcaatacc atggctgatg agtccctcat cacaggagaa gccatgccag
2521 tcactaagaa acccggaagc actgtaattg cggggtctat aaatgcacat ggctctgtgc
2581 tcattaaagc tacccacgtg ggcaatgaca ccactttggc tcagattgtg aaactggtgg
2641 aagaggctca gatgtcaaag gcacccattc agcagctggc tgaccggttt agtggatatt
2701 ttgtcccatt tatcatcatc atgtcaactt tgacgttggt ggtatggatt gtaatcggtt
2761 ttatcgattt tggtgttgtt cagagatact ttcctaaccc caacaagcac atctcccaga
2821 cagaggtgat catccggttt gctttccaga cgtccatcac ggtgctgtgc attgcctgcc
2881 cctgctccct ggggctggcc acgcccacgg ctgtcatggt gggcaccggg gtggccgcgc
2941 agaacggcat cctcatcaag ggaggcaagc ccctggagat ggcgcacaag ataaagactg
3001 tgatgtttga caagactggc accattaccc atggcgtccc cagggtcatg cgggtgctcc
3061 tgctggggga tgtggccaca ctgcccctca ggaaggttct ggctgtggtg gggactgcgg
3121 aggccagcag tgaacacccc ttgggcgtgg cagtcaccaa atactgtaaa gaggaacttg
3181 gaacagagac cttgggatac tgcacggact tccaggcagt gccaggctgt ggaattgggt
3241 gcaaagtcag caacgtggaa ggcatcctgg cccacagtga gcgccctttg agtgcaccgg
3301 ccagtcacct gaatgaggct ggcagccttc ccgcagaaaa agatgcagtc ccccagacct
3361 tctctgtgct gattggaaac cgtgagtggc tgaggcgcaa cggtttaacc atttctagcg
3421 atgtcagtga cgctatgaca gaccacgaga tgaaaggaca gacagccatc ctggtggcta
3481 ttgacggtgt gctctgtggg atgatcgcaa tcgcagacgc tgtcaagcag gaggctgccc
3541 tggctgtgca cacgctgcag agcatgggtg tggacgtggt tctgatcacg ggggacaacc
3601 ggaagacagc cagagctatt gccacccagg ttggcatcaa caaagtcttt gcagaggtgc
3661 tgccttcgca caaggtggcc aaggtccagg agctccagaa taaagggaag aaagtcgcca
3721 tggtggggga tggggtcaat gactccccgg ccttggccca ggcagacatg ggtgtggcca
3781 ttggcaccgg cacggatgtg gccatcgagg cagccgacgt cgtccttatc agaaatgatt
3841 tgctggatgt ggtggctagc attcaccttt ccaagaggac tgtccgaagg atacgcatca
3901 acctggtcct ggcactgatt tataacctgg ttgggatacc cattgcagca ggtgtcttca
3961 tgcccatcgg cattgtgctg cagccctgga tgggctcagc ggccatggca gcctcctctg
4021 tgtctgtggt gctctcatcc ctgcagctca agtgctataa gaagcctgac ctggagaggt
4081 atgaggcaca ggcgcatggc cacatgaagc ccctgacggc atcccaggtc agtgtgcaca
4141 taggcatgga tgacaggtgg cgggactccc ccagggccac accatgggac caggtcagct
4201 atgtcagcca ggtgtcgctg tcctccctga cgtccgacaa gccatctcgg cacagcgctg
4261 cagcagacga tgatggggac aagtggtctc tgctcctgaa tggcagggat gaggagcagt
4321 acatctgatg acttcaggca ggcgggccgg ggcagggact tgcctccact caccacaagc
4381 tgagcaggac agccagca
//