LOCUS BC143975 4308 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ATPase, Cu++ transporting, beta polypeptide, mRNA
(cDNA clone MGC:177510 IMAGE:9052493), complete cds.
ACCESSION BC143975
VERSION BC143975.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4308)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4308)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 16 Row: H Column: 6.
FEATURES Location/Qualifiers
source 1..4308
/db_xref="H-InvDB:HIT000502414"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177510 IMAGE:9052493"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GCAATATC"
gene 1..4308
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
CDS 75..4238
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/codon_start=1
/product="ATP7B protein"
/protein_id="AAI43976.1"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
/translation="MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGY
EGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKY
VPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSS
IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS
LGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE
ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGS
GTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISV
SLAEGTATVLYNPAVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTD
GTPTSLQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIER
NLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNI
ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEE
IGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSM
VLDHNIIPGLSILNLIFFILCTFVQSKTSEALAKLMSLQATEATVVTLGEDNLIIREE
QVPMELVQRGDIVRVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGS
INAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTL
TLVVWIVIGFIDFGVVQKYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATP
TAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVAT
LPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSN
VEGILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSVLIGNREWLRRNGLTISSDVS
DAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNR
KTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGV
AIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAA
GVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYEAQAHGHMKPLTAS
QVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLL
NGRDEEQYI"
BASE COUNT 1047 a 1121 c 1183 g 957 t
ORIGIN
1 cgctctcctc caccgaccag gtgacctttt gctctgagcc agatcagaga agaattcggt
61 gtccgtgcgg gacgatgcct gagcaggaga gacagatcac agccagagaa ggggccagtc
121 ggaaaatctt atctaagctt tctttgccta cccgtgcctg ggaaccagca atgaagaaga
181 gttttgcttt tgacaatgtt ggctatgaag gtggtctgga tggcctgggc ccttcttctc
241 aggtggccac cagcacagtc aggatcttgg gcatgacttg ccagtcatgt gtgaagtcca
301 ttgaggacag gatttccaat ttgaaaggca tcatcagcat gaaggtttcc ctggaacaag
361 gcagtgccac tgtgaaatat gtgccatcgg ttgtgtgcct gcaacaggtt tgccatcaaa
421 ttggggacat gggcttcgag gccagcattg cagaaggaaa ggcagcctcc tggccctcaa
481 ggtccttgcc tgcccaggag gctgtggtca agctccgggt ggagggcatg acctgccagt
541 cctgtgtcag ctccattgaa ggcaaggtcc ggaaactgca aggagtagtg agagtcaaag
601 tctcactcag caaccaagag gccgtcatca cttatcagcc ttatctcatt cagcccgaag
661 acctcaggga ccatgtaaat gacatgggat ttgaagctgc catcaagagc aaagtggctc
721 ccttaagcct gggaccaatt gatattgagc ggttacaaag cactaaccca aagagacctt
781 tatcttctgc taaccagaat tttaataatt ctgagacctt ggggcaccaa ggaagccatg
841 tggtcaccct ccaactgaga atagatggaa tgcattgtaa gtcttgcgtc ttgaatattg
901 aagaaaatat tggccagctc ctaggggttc aaagtattca agtgtccttg gagaacaaaa
961 ctgcccaagt aaagtatgac ccttcttgta ccagcccagt ggctctgcag agggctatcg
1021 aggcacttcc acctgggaat tttaaagttt ctcttcctga tggagccgaa gggagtggga
1081 cagatcacag gtcttccagt tctcattccc ctggctcccc accgagaaac caggtccagg
1141 gcacatgcag taccactctg attgccattg ccggcatgac ctgtgcatcc tgtgtccatt
1201 ccattgaagg catgatctcc caactggaag gggtgcagca aatatcggtg tctttggccg
1261 aagggactgc aacagttctt tataatcccg ctgtaattag cccagaagaa ctcagagctg
1321 ctatagaaga catgggattt gaggcttcag tcgtttctga aagctgttct actaaccctc
1381 ttggaaacca cagtgctggg aattccatgg tgcaaactac agatggtaca cctacatctc
1441 tgcaggaagt ggctccccac actgggaggc tccctgcaaa ccatgccccg gacatcttgg
1501 caaagtcccc acaatcaacc agagcagtgg caccgcagaa gtgcttctta cagatcaaag
1561 gcatgacctg tgcatcctgt gtgtctaaca tagaaaggaa tctgcagaaa gaagctggtg
1621 ttctctccgt gttggttgcc ttgatggcag gaaaggcaga gatcaagtat gacccagagg
1681 tcatccagcc cctcgagata gctcagttca tccaggacct gggttttgag gcagcagtca
1741 tggaggacta cgcaggctcc gatggcaaca ttgagctgac aatcacaggg atgacctgcg
1801 cgtcctgtgt ccacaacata gagtccaaac tcacgaggac aaatggcatc acttatgcct
1861 ccgttgccct tgccaccagc aaagcccttg ttaagtttga cccggaaatt atcggtccac
1921 gggatattat caaaattatt gaggaaattg gctttcatgc ttccctggcc cagagaaacc
1981 ccaacgctca tcacttggac cacaagatgg aaataaagca gtggaagaag tctttcctgt
2041 gcagcctggt gtttggcatc cctgtcatgg ccttaatgat ctatatgctg atacccagca
2101 acgagcccca ccagtccatg gtcctggacc acaacatcat tccaggactg tccattctaa
2161 atctcatctt ctttatcttg tgtacctttg tccagagcaa aacctcagaa gccctggcta
2221 aactcatgtc tctccaagcc acagaagcca ccgttgtgac ccttggtgag gacaatttaa
2281 tcatcaggga ggagcaagtc cccatggagc tggtgcagcg gggcgatatc gtcagggtgg
2341 tccctggggg aaagtttcca gtggatggga aagtcctgga aggcaatacc atggctgatg
2401 agtccctcat cacaggagaa gccatgccag tcactaagaa acccggaagc actgtaattg
2461 cggggtctat aaatgcacat ggctctgtgc tcattaaagc tacccacgtg ggcaatgaca
2521 ccactttggc tcagattgtg aaactggtgg aagaggctca gatgtcaaag gcacccattc
2581 agcagctggc tgaccggttt agtggatatt ttgtcccatt tatcatcatc atgtcaactt
2641 tgacgttggt ggtatggatt gtaatcggtt ttatcgattt tggtgttgtt cagaaatact
2701 ttcctaaccc caacaagcac atctcccaga cagaggtgat catccggttt gctttccaga
2761 cgtccatcac ggtgctgtgc attgcctgcc cctgctccct ggggctggcc acgcccacgg
2821 ctgtcatggt gggcaccggg gtggccgcgc agaacggcat cctcatcaag ggaggcaagc
2881 ccctggagat ggcgcacaag ataaagactg tgatgtttga caagactggc accattaccc
2941 atggcgtccc cagggtcatg cgggtgctcc tgctggggga tgtggccaca ctgcccctca
3001 ggaaggttct ggctgtggtg gggactgcgg aggccagcag tgaacacccc ttgggcgtgg
3061 cagtcaccaa atactgtaaa gaggaacttg gaacagagac cttgggatac tgcacggact
3121 tccaggcagt gccaggctgt ggaattgggt gcaaagtcag caacgtggaa ggcatcctgg
3181 cccacagtga gcgccctttg agtgcaccgg ccagtcacct gaatgaggct ggcagccttc
3241 ccgcagaaaa agatgcagcc ccccagacct tctctgtgct gattggaaac cgtgagtggc
3301 tgaggcgcaa cggtttaacc atttctagcg atgtcagtga cgctatgaca gaccacgaga
3361 tgaaaggaca gacagccatc ctggtggcta ttgacggtgt gctctgtggg atgatcgcaa
3421 tcgcagacgc tgtcaagcag gaggctgccc tggctgtgca cacgctgcag agcatgggtg
3481 tggacgtggt tctgatcacg ggggacaacc ggaagacagc cagagctatt gccacccagg
3541 ttggcatcaa caaagtcttt gcagaggtgc tgccttcgca caaggtggcc aaggtccagg
3601 agctccagaa taaagggaag aaagtcgcca tggtggggga tggggtcaat gactccccgg
3661 ccttggccca ggcagacatg ggtgtggcca ttggcaccgg cacggatgtg gccatcgagg
3721 cagccgacgt cgtccttatc agaaatgatt tgctggatgt ggtggctagc attcaccttt
3781 ccaagaggac tgtccgaagg atacgcatca acctggtcct ggcactgatt tataacctgg
3841 ttgggatacc cattgcagca ggtgtcttca tgcccatcgg cattgtgctg cagccctgga
3901 tgggctcagc ggccatggca gcctcctctg tgtctgtggt gctctcatcc ctgcagctca
3961 agtgctataa gaagcctgac ctggagaggt atgaggcaca ggcgcatggc cacatgaagc
4021 ccctgacggc atcccaggtc agtgtgcaca taggcatgga tgacaggtgg cgggactccc
4081 ccagggccac accatgggac caggtcagct atgtcagcca ggtgtcgctg tcctccctga
4141 cgtccgacaa accatctcgg cacagcgctg cagcagacga tgatggggac aagtggtctc
4201 tgctcctgaa tggcagggat gaggagcagt acatctgatg acttcaggca ggcgggccgg
4261 ggcagggact tgcctccact caccacaagc tgagcaggac agccagca
//