LOCUS BC143973 4340 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ATPase, Cu++ transporting, beta polypeptide, mRNA
(cDNA clone MGC:177508 IMAGE:9052491), complete cds.
ACCESSION BC143973
VERSION BC143973.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4340)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4340)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 16 Row: H Column: 2.
FEATURES Location/Qualifiers
source 1..4340
/db_xref="H-InvDB:HIT000502412"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177508 IMAGE:9052491"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GCCAGCAG"
gene 1..4340
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
CDS 75..4277
/gene="ATP7B"
/gene_synonym="PWD"
/gene_synonym="WC1"
/gene_synonym="WD"
/codon_start=1
/product="ATP7B protein"
/protein_id="AAI43974.1"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
/translation="MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGY
EGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKY
VPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSS
IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLS
LGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE
ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGS
GTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISV
SLAEGTATVLYNPAVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTD
GTPTSLQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIER
NLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNI
ELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEE
IGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSM
VLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIA
YVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL
QATEATVVTLGEDNLIIREEQVPMELVQRGDIVRVVPGGKFPVDGKVLEGNTMADESL
ITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQ
QLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQKYFPIKTVMFDKTGTITHGVP
RVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQ
AVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAAPQTFSVLIGNREW
LRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQS
MGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGV
NDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVL
ALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYE
AQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSA
AADDDGDKWSLLLNGRDEEQYI"
BASE COUNT 1048 a 1115 c 1190 g 987 t
ORIGIN
1 cggtctcctc caccgaccag gtgacctttt gctctgagcc agatcagaga agaattcggt
61 gtccgtgcgg gacgatgcct gagcaggaga gacagatcac agccagagaa ggggccagtc
121 ggaaaatctt atctaagctt tctttgccta cccgtgcctg ggaaccagca atgaagaaga
181 gttttgcttt tgacaatgtt ggctatgaag gtggtctgga tggcctgggc ccttcttctc
241 aggtggccac cagcacagtc aggatcttgg gcatgacttg ccagtcatgt gtgaagtcca
301 ttgaggacag gatttccaat ttgaaaggca tcatcagcat gaaggtttcc ctggaacaag
361 gcagtgccac tgtgaaatat gtgccatcgg ttgtgtgcct gcaacaggtt tgccatcaaa
421 ttggggacat gggcttcgag gccagcattg cagaaggaaa ggcagcctcc tggccctcaa
481 ggtccttgcc tgcccaggag gctgtggtca agctccgggt ggagggcatg acctgccagt
541 cctgtgtcag ctccattgaa ggcaaggtcc ggaaactgca aggagtagtg agagtcaaag
601 tctcactcag caaccaagag gccgtcatca cttatcagcc ttatctcatt cagcccgaag
661 acctcaggga ccatgtaaat gacatgggat ttgaagctgc catcaagagc aaagtggctc
721 ccttaagcct gggaccaatt gatattgagc ggttacaaag cactaaccca aagagacctt
781 tatcttctgc taaccagaat tttaataatt ctgagacctt ggggcaccaa ggaagccatg
841 tggtcaccct ccaactgaga atagatggaa tgcattgtaa gtcttgcgtc ttgaatattg
901 aagaaaatat tggccagctc ctaggggttc aaagtattca agtgtccttg gagaacaaaa
961 ctgcccaagt aaagtatgac ccttcttgta ccagcccagt ggctctgcag agggctatcg
1021 aggcacttcc acctgggaat tttaaagttt ctcttcctga tggagccgaa gggagtggga
1081 cagatcacag gtcttccagt tctcattccc ctggctcccc accgagaaac caggtccagg
1141 gcacatgcag taccactctg attgccattg ccggcatgac ctgtgcatcc tgtgtccatt
1201 ccattgaagg catgatctcc caactggaag gggtgcagca aatatcggtg tctttggccg
1261 aagggactgc aacagttctt tataatcccg ctgtaattag cccagaagaa ctcagagctg
1321 ctatagaaga catgggattt gaggcttcag tcgtttctga aagctgttct actaaccctc
1381 ttggaaacca cagtgctggg aattccatgg tgcaaactac agatggtaca cctacatctc
1441 tgcaggaagt ggctccccac actgggaggc tccctgcaaa ccatgccccg gacatcttgg
1501 caaagtcccc acaatcaacc agagcagtgg caccgcagaa gtgcttctta cagatcaaag
1561 gcatgacctg tgcatcctgt gtgtctaaca tagaaaggaa tctgcagaaa gaagctggtg
1621 ttctctccgt gttggttgcc ttgatggcag gaaaggcaga gatcaagtat gacccagagg
1681 tcatccagcc cctcgagata gctcagttca tccaggacct gggttttgag gcagcagtca
1741 tggaggacta cgcaggctcc gatggcaaca ttgagctgac aatcacaggg atgacctgcg
1801 cgtcctgtgt ccacaacata gagtccaaac tcacgaggac aaatggcatc acttatgcct
1861 ccgttgccct tgccaccagc aaagcccttg ttaagtttga cccggaaatt atcggtccac
1921 gggatattat caaaattatt gaggaaattg gctttcatgc ttccctggcc cagagaaacc
1981 ccaacgctca tcacttggac cacaagatgg aaataaagca gtggaagaag tctttcctgt
2041 gcagcctggt gtttggcatc cctgtcatgg ccttaatgat ctatatgctg atacccagca
2101 acgagcccca ccagtccatg gtcctggacc acaacatcat tccaggactg tccattctaa
2161 atctcatctt ctttatcttg tgtacctttg tccagctcct cggtgggtgg tacttctacg
2221 ttcaggccta caaatctctg agacacaggt cagccaacat ggacgtgctc atcgtcctgg
2281 ccacaagcat tgcttatgtt tattctctgg tcatcctggt ggttgctgtg gctgagaagg
2341 cggagaggag ccctgtgaca ttcttcgaca cgccccccat gctctttgtg ttcattgccc
2401 tgggccggtg gctggaacac ttggcaaaga gcaaaacctc agaagccctg gctaaactca
2461 tgtctctcca agccacagaa gccaccgttg tgacccttgg tgaggacaat ttaatcatca
2521 gggaggagca agtccccatg gagctggtgc agcggggcga tatcgtcagg gtggtccctg
2581 ggggaaagtt tccagtggat gggaaagtcc tggaaggcaa taccatggct gatgagtccc
2641 tcatcacagg agaagccatg ccagtcacta agaaacccgg aagcactgta attgcggggt
2701 ctataaatgc acatggctct gtgctcatta aagctaccca cgtgggcaat gacaccactt
2761 tggctcagat tgtgaaactg gtggaagagg ctcagatgtc aaaggcaccc attcagcagc
2821 tggctgaccg gtttagtgga tattttgtcc catttatcat catcatgtca actttgacgt
2881 tggtggtatg gattgtaatc ggttttatcg attttggtgt tgttcagaaa tactttccta
2941 taaagactgt gatgtttgac aagactggca ccattaccca tggcgtcccc agggtcatgc
3001 gggtgctcct gctgggggat gtggccacac tgcccctcag gaaggttctg gctgtggtgg
3061 ggactgcgga ggccagcagt gaacacccct tgggcgtggc agtcaccaaa tactgtaaag
3121 aggaacttgg aacagagacc ttgggatact gcacggactt ccaggcagtg ccaggctgtg
3181 gaattgggtg caaagtcagc aacgtggaag gcatcctggc ccacagtgag cgccctttga
3241 gtgcaccggc cagtcacctg aatgaggctg gcagccttcc cgcagaaaaa gatgcagccc
3301 cccagacctt ctctgtgctg attggaaacc gtgagtggct gaggcgcaac ggtttaacca
3361 tttctagcga tgtcagtgac gctatgacag accacgagat gaaaggacag acagccatcc
3421 tggtggctat tgacggtgtg ctctgtggga tgatcgcaat cgcagacgct gtcaagcagg
3481 aggctgccct ggctgtgcac acgctgcaga gcatgggtgt ggacgtggtt ctgatcacgg
3541 gggacaaccg gaagacagcc agagctattg ccacccaggt tggcatcaac aaagtctttg
3601 cagaggtgct gccttcgcac aaggtggcca aggtccagga gctccagaat aaagggaaga
3661 aagtcgccat ggtgggggat ggggtcaatg actccccggc cttggcccag gcagacatgg
3721 gtgtggccat tggcaccggc acggatgtgg ccatcgaggc agccgacgtc gtccttatca
3781 gaaatgattt gctggatgtg gtggctagca ttcacctttc caagaggact gtccgaagga
3841 tacgcatcaa cctggtcctg gcactgattt ataacctggt tgggataccc attgcagcag
3901 gtgtcttcat gcccatcggc attgtgctgc agccctggat gggctcagcg gccatggcag
3961 cctcctctgt gtctgtggtg ctctcatccc tgcagctcaa gtgctataag aagcctgacc
4021 tggagaggta tgaggcacag gcgcatggcc acatgaagcc cctgacggca tcccaggtca
4081 gtgtgcacat aggcatggat gacaggtggc gggactcccc cagggccaca ccatgggacc
4141 aggtcagcta tgtcagccag gtgtcgctgt cctccctgac gtccgacaag ccatctcggc
4201 acagcgctgc agcagacgat gatggggaca agtggtctct gctcctgaat ggcagggatg
4261 aggagcagta catctgatga cttcaggcag gcgggccggg gcagggactt gcctccactc
4321 accacaagct gagcaggaca
//