LOCUS BC143902 1803 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens angiopoietin 2, mRNA (cDNA clone MGC:177437
IMAGE:9052420), complete cds.
ACCESSION BC143902
VERSION BC143902.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1803)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1803)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 16 Row: P Column: 1.
FEATURES Location/Qualifiers
source 1..1803
/db_xref="H-InvDB:HIT000502342"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177437 IMAGE:9052420"
/tissue_type="Colon, PCR rescued clones"
/clone_lib="NIH_MGC_295"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GCCCACTC"
gene 1..1803
/gene="ANGPT2"
/gene_synonym="AGPT2"
/gene_synonym="ANG2"
/db_xref="GeneID:285"
/db_xref="HGNC:HGNC:485"
/db_xref="MIM:601922"
CDS 58..1545
/gene="ANGPT2"
/gene_synonym="AGPT2"
/gene_synonym="ANG2"
/codon_start=1
/product="angiopoietin 2"
/protein_id="AAI43903.1"
/db_xref="GeneID:285"
/db_xref="HGNC:HGNC:485"
/db_xref="MIM:601922"
/translation="MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYT
FLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQ
DNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQL
LEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQV
LVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSKDPTVAKEE
QISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDF
QRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLS
SEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACG
PSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF"
BASE COUNT 599 a 390 c 408 g 406 t
ORIGIN
1 ctggacgtgt gtttgccctc aagtttgcta agctgctggt ttattactga agaaagaatg
61 tggcagattg ttttctttac tctgagctgt gatcttgtct tggccgcagc ctataacaac
121 tttcggaaga gcatggacag cataggaaag aagcaatatc aggtccagca tgggtcctgc
181 agctacactt tcctcctgcc agagatggac aactgccgct cttcctccag cccctacgtg
241 tccaatgctg tgcagaggga cgcgccgctc gaatacgatg actcggtgca gaggctgcaa
301 gtgctggaga acatcatgga aaacaacact cagtggctaa tgaagcttga gaattatatc
361 caggacaaca tgaagaaaga aatggtagag atacagcaga atgcagtaca gaaccagacg
421 gctgtgatga tagaaatagg gacaaacctg ttgaaccaaa cagcggagca aacgcggaag
481 ttaactgatg tggaagccca agtattaaat cagaccacga gacttgaact tcagctcttg
541 gaacactccc tctcgacaaa caaattggaa aaacagattt tggaccagac cagtgaaata
601 aacaaattgc aagataagaa cagtttccta gaaaagaagg tgctagctat ggaagacaag
661 cacatcatcc aactacagtc aataaaagaa gagaaagatc agctacaggt gttagtatcc
721 aagcaaaatt ccatcattga agaactagaa aaaaaaatag tgactgccac ggtgaataat
781 tcagttcttc agaagcagca acatgatctc atggagacag ttaataactt actgactatg
841 atgtccacat caaactctaa ggaccccact gttgctaaag aagaacaaat cagcttcaga
901 gactgtgctg aagtattcaa atcaggacac accacgaatg gcatctacac gttaacattc
961 cctaattcta cagaagagat caaggcctac tgtgacatgg aagctggagg aggcgggtgg
1021 acaattattc agcgacgtga ggatggcagc gttgattttc agaggacttg gaaagaatat
1081 aaagtgggat ttggtaaccc ttcaggagaa tattggctgg gaaatgagtt tgtttcgcaa
1141 ctgactaatc agcaacgcta tgtgcttaaa atacacctta aagactggga agggaatgag
1201 gcttactcat tgtatgaaca tttctatctc tcaagtgaag aactcaatta taggattcac
1261 cttaaaggac ttacagggac agccggcaaa ataagcagca tcagccaacc aggaaatgat
1321 tttagcacaa aggatggaga caacgacaaa tgtatttgca aatgttcaca aatgctaaca
1381 ggaggctggt ggtttgatgc atgtggtcct tccaacttga acggaatgta ctatccacag
1441 aggcagaaca caaataagtt caacggcatt aaatggtact actggaaagg ctcaggctat
1501 tcgctcaagg ccacaaccat gatgatccga ccagcagatt tctaaacatc ccagtccacc
1561 tgaggaactg tctcgaacta ttttcaaaga cttaagccca gtgcactgaa agtcacggct
1621 gcgcactgtg tcctcttcca ccacagaggg cgtgtgctcg gtgctgacgg gacccacatg
1681 ctccagatta gagcctgtaa actttatcac ttaaacttgc atcacttaac ggaccaaagc
1741 aagaccctaa acatccataa ttgtgattag acagaacacc tatgcaaaga tgaacccgag
1801 gct
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