LOCUS BC143586 1368 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens potassium channel, subfamily K, member 2, mRNA (cDNA
clone MGC:177114 IMAGE:9052097), complete cds.
ACCESSION BC143586
VERSION BC143586.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1368)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1368)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: F Column: 18.
FEATURES Location/Qualifiers
source 1..1368
/db_xref="H-InvDB:HIT000502036"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177114 IMAGE:9052097"
/tissue_type="Lung, PCR rescued clones"
/clone_lib="NIH_MGC_299"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: AGCACccc"
gene 1..1368
/gene="KCNK2"
/gene_synonym="hTREK-1c"
/gene_synonym="hTREK-1e"
/gene_synonym="K2p2.1"
/gene_synonym="TPKC1"
/gene_synonym="TREK"
/gene_synonym="TREK-1"
/gene_synonym="TREK1"
/db_xref="GeneID:3776"
/db_xref="HGNC:HGNC:6277"
/db_xref="MIM:603219"
CDS 61..1296
/gene="KCNK2"
/gene_synonym="hTREK-1c"
/gene_synonym="hTREK-1e"
/gene_synonym="K2p2.1"
/gene_synonym="TPKC1"
/gene_synonym="TREK"
/gene_synonym="TREK-1"
/gene_synonym="TREK1"
/codon_start=1
/product="potassium channel, subfamily K, member 2"
/protein_id="AAI43587.1"
/db_xref="GeneID:3776"
/db_xref="HGNC:HGNC:6277"
/db_xref="MIM:603219"
/translation="MAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKW
KTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDEL
IQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCI
IYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFG
CVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWF
WILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSV
EIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYL
NGLTPHCAGEEIAVIENIK"
BASE COUNT 360 a 313 c 333 g 362 t
ORIGIN
1 aaagccgggg aaaatgcctg cccgtgcagc tcggagcgcg cagcccgtct ctgaataaga
61 atggcggcac ctgacttgct ggatcctaaa tctgccgctc agaactccaa accgaggctc
121 tcgttttcca cgaaacccac agtgcttgct tcccgggtgg agagtgacac gaccattaat
181 gttatgaaat ggaagacggt ctccacgata ttcctggtgg ttgtcctcta tctgatcatc
241 ggagccaccg tgttcaaagc attggagcag cctcatgaga tttcacagag gaccaccatt
301 gtgatccaga agcaaacatt catatcccaa cattcctgtg tcaattcgac ggagctggat
361 gaactcattc agcaaatagt ggcagcaata aatgcaggga ttataccgtt aggaaacacc
421 tccaatcaaa tcagtcactg ggatttggga agttccttct tctttgctgg cactgttatt
481 acaaccatag gatttggaaa catctcacca cgcacagaag gcggcaaaat attctgtatc
541 atctatgcct tactgggaat tcccctcttt ggttttctct tggctggagt tggagatcag
601 ctaggcacca tatttggaaa aggaattgcc aaagtggaag atacgtttat taagtggaat
661 gttagtcaga ccaagattcg catcatctca acaatcatat ttatactatt tggctgtgta
721 ctctttgtgg ctctgcctgc gatcatattc aaacacatag aaggctggag tgccctggac
781 gccatttatt ttgtggttat cactctaaca actattggat ttggtgacta cgttgcaggt
841 ggatccgata ttgaatatct ggacttctat aagcctgtcg tgtggttctg gatccttgta
901 gggcttgctt actttgctgc tgtcctgagc atgattggag attggctccg agtgatatct
961 aaaaagacaa aagaagaggt gggagagttc agagcacacg ctgctgagtg gacagccaac
1021 gtcacagccg aattcaaaga aaccaggagg cgactgagtg tggagattta tgacaagttc
1081 cagcgggcca cctccatcaa gcggaagctc tcggcagaac tggctggaaa ccacaatcag
1141 gagctgactc cttgtaggag gaccctgtca gtgaaccacc tgaccagcga gagggatgtc
1201 ttgcctccct tactgaagac tgagagtatc tatctgaatg gtttgacgcc acactgtgct
1261 ggtgaagaga ttgctgtgat tgagaacatc aaatagccct ctctttaaat aaccttaggc
1321 atagccatag gtgaggactt ctctatgctc tttatgactg ttgctggt
//