LOCUS BC143529 3590 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens mastermind-like 2 (Drosophila), mRNA (cDNA clone
MGC:177055 IMAGE:9052038), complete cds.
ACCESSION BC143529
VERSION BC143529.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3590)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3590)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: N Column: 17.
FEATURES Location/Qualifiers
source 1..3590
/db_xref="H-InvDB:HIT000501980"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177055 IMAGE:9052038"
/tissue_type="Lung and heart, PCR rescued clones"
/clone_lib="NIH_MGC_314"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: CTCCCTGG"
gene 1..3590
/gene="MAML2"
/gene_synonym="MAM-3"
/gene_synonym="MAM2"
/gene_synonym="MAM3"
/gene_synonym="MLL-MAML2"
/db_xref="GeneID:84441"
/db_xref="HGNC:HGNC:16259"
/db_xref="MIM:607537"
CDS 39..3497
/gene="MAML2"
/gene_synonym="MAM-3"
/gene_synonym="MAM2"
/gene_synonym="MAM3"
/gene_synonym="MLL-MAML2"
/codon_start=1
/product="MAML2 protein"
/protein_id="AAI43530.1"
/db_xref="GeneID:84441"
/db_xref="HGNC:HGNC:16259"
/db_xref="MIM:607537"
/translation="MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARI
AVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATT
TAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPAST
PGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGG
LQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCS
KHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATI
KQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFS
MANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQ
QHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSK
VMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQ
ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ
QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPL
QQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNS
QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYK
DQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSL
STAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSN
NNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ
EALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQ
TLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQ
SSRVFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLDE
ILGNNS"
BASE COUNT 1070 a 1054 c 798 g 668 t
ORIGIN
1 tcaccatccc agaggcagca atcattgtgt ccggtaagat gggggacaca gcgcccccgc
61 aggcccccgc aggagggcta gggggggcct ctggggcggg gctccttgga gggggctcag
121 tcaccccgag agtgcacagt gctatcgtgg agcgcctccg ggctcggatc gctgtctgcc
181 gccaacacca cctgagctgt gaaggacgat atgaacgagg tagggccgag agctcagacc
241 gggaaagaga aagcaccttg cagctcctga gccttgtaca gcatggccag ggggcaagga
301 aagctggcaa acacaccaag gccaccgcca ctgctgccac cactacagcc cctccaccgc
361 cccctgctgc ccctcctgcg gcctcccaag cagcagcaac agcagcccca ccgcccccac
421 cagactatca ccatcaccac cagcagcacc tgctgaacag tagcaataat ggtggcagtg
481 gtgggataaa cggagagcag cagccgcccg cttcaacccc aggggaccag aggaactcag
541 ccctgattgc gctccagggt tccttgaaaa gaaaacaggt agttaaccta tctcctgcca
601 acagcaagcg acccaatggc tttgtggaca actcatttct tgatatcaaa agaattcgtg
661 ttggggagaa tctctctgca ggacaaggtg gcctccaaat aaacaatgga caaagtcaga
721 ttatgtcagg gaccttgcct atgagccaag cacccctgcg aaagactaac actctgccat
781 cccatacaca ttctcctggc aatggcctgt ttaacatggg cttaaaggag gtaaagaagg
841 agccaggaga gactctgtct tgcagtaagc acatggatgg ccaaatgacc caagagaata
901 tttttcctaa taggtacgga gacgaccctg gagaacaact gatggatcct gagctgcagg
961 aactgttcaa tgaactgacc aacatatctg tgcctcccat gagtgacctt gaactggaga
1021 acatgatcaa tgccaccata aagcaggatg acccatttaa cattgacttg ggtcagcaaa
1081 gccagaggag cacacctagg ccctccttac ccatggagaa aatagtgatc aaaagtgaat
1141 actcaccggg cttgactcag ggcccctcag gctctcctca gctgaggccc ccatcagctg
1201 gccccgcatt ctccatggcc aactctgccc tctccacttc gtctccaatc ccttcagtcc
1261 ctcagagcca ggctcagcct cagacaggct ccggagcaag ccgggccttg ccaagctggc
1321 aggaagtatc ccatgcccag cagctcaaac agatagctgc taatcgtcag cagcatgccc
1381 ggatgcagca gcaccagcag cagcaccagc ctaccaactg gtcagccttg ccctcctctg
1441 ctggaccatc accaggtcca tttgggcagg agaaaatccc cagcccttct tttggtcagc
1501 agacattcag cccacagagc tcccccatgc ctggggtagc tggcggcagc ggccagtcga
1561 aagtaatggc taactacatg tacaaggccg gcccctcagc ccagggtggg cacctagatg
1621 tcctcatgca gcaaaagcct caggatctca gtcgaagttt tattaacaac ccgcacccag
1681 ccatggagcc ccgtcagggc aacaccaagc ctttgtttca ttttaactca gatcaagcga
1741 accagcagat gccttctgtt ttgccttccc agaacaagcc ttctctccta cactacaccc
1801 aacagcaaca gcagcaacag cagcagcagc agcagcagca gcagcagcaa cagcagcagc
1861 agcaacagca acagcaacag caacagcaga gttcaatttc agctcaacaa cagcaacagc
1921 agcagagctc aatttcagcc caacagcagc agcagcagca acaacagcag cagcagcagc
1981 aacaacaaca gcaacaacag cagcagcagc agcagcaaca accatcttct cagcctgccc
2041 aatctctacc aagccagcct ttgctaaggt cacctttgcc acttcagcaa aagctcctac
2101 ttcagcaaat gcagaatcag cccattgcag gaatgggata ccaagtctcc caacaacaga
2161 gacaggatca acactctgtg gtaggccaga acacaggccc cagtccaagt cctaacccct
2221 gctcaaatcc aaacactgga agtggttaca tgaactccca gcaatcactg ttgaatcagc
2281 aattgatggg aaagaagcag actctacaga ggcagatcat ggagcagaaa cagcaacttc
2341 ttctccagca gcagatgctg gctgacgcgg agaaaattgc tccacaagat cagataaacc
2401 gacatttgtc aaggccacct ccagattata aagaccaaag aagaaatgtg ggcaatatgc
2461 aaccaactgc tcagtattct ggtggctcat ccacaataag cttaaactct aaccaggctt
2521 tggcaaaccc agtttcaaca cacaccattt taactcccaa ttccagcctc ctgtctactt
2581 ctcacgggac aagaatgcca tcattatcta cagcagttca gaatatgggg atgtatggaa
2641 atctgccttg taatcaacct aacacataca gtgtcacttc aggaatgaat caattgaccc
2701 aacagagaaa cccaaagcaa ttgttagcaa atcaaaacaa ccctatgatg ccacggccac
2761 ctaccttagg gccaagtaat aataacaatg tagccacttt tggagctgga tctgttggta
2821 attcacaaca attgagacca aatttaaccc atagtatggc aagcatgcca ccacagagaa
2881 catcaaacgt aatgatcaca tccaacacaa ctgcaccaaa ctgggcctct caagaaggaa
2941 caagcaaaca gcaagaagcc ctgacgtctg caggagtccg cttccccaca ggtacacctg
3001 cagcctatac cccaaatcag tcactgcaac aggcagtagg tagccagcaa ttttcccaga
3061 gggcagtggc tcctcctaac cagttaacac cagcagtgca aatgagaccc atgaaccaaa
3121 tgagccaaac actaaatggg caaaccatgg gtcccctcag gggtctgaat ctcagaccca
3181 atcagctaag cacacagatt ttgcctaatt tgaatcagtc aggaacaggg ttgaatcagt
3241 cgaggacggg catcaaccag ccaccatccc tgacgcccag caattttcct tcacccaacc
3301 aaagttccag ggtttttcaa ggaactgacc acagcagtga cttagctttt gacttcctca
3361 gccaacaaaa tgataacatg ggccctgccc taaacagtga tgctgatttc attgattctt
3421 tattgaagac agagcctggt aatgatgact ggatgaaaga catcaatctt gatgaaatct
3481 tggggaacaa ttcctaaaga agaaagggaa gacaatttac aaactccaag cactaaaagg
3541 cagtatatta cagaaactct gtagaggctg aactgttgat gttcaggtgg
//