LOCUS BC143456 2797 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens calcium/calmodulin-dependent serine protein kinase
(MAGUK family), mRNA (cDNA clone MGC:176981 IMAGE:9051964),
complete cds.
ACCESSION BC143456
VERSION BC143456.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2797)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2797)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: L Column: 1.
FEATURES Location/Qualifiers
source 1..2797
/db_xref="H-InvDB:HIT000501910"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176981 IMAGE:9051964"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_310"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: GTCCGAAT"
gene 1..2797
/gene="CASK"
/gene_synonym="CAGH39"
/gene_synonym="CMG"
/gene_synonym="LIN2"
/gene_synonym="MICPCH"
/db_xref="GeneID:8573"
/db_xref="HGNC:HGNC:1497"
/db_xref="MIM:300172"
CDS 20..2713
/gene="CASK"
/gene_synonym="CAGH39"
/gene_synonym="CMG"
/gene_synonym="LIN2"
/gene_synonym="MICPCH"
/codon_start=1
/product="calcium/calmodulin-dependent serine protein
kinase (MAGUK family)"
/protein_id="AAI43457.1"
/db_xref="GeneID:8573"
/db_xref="HGNC:HGNC:1497"
/db_xref="MIM:300172"
/translation="MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVD
VAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFE
IVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKL
GGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLP
FYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWL
KERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSED
PTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQI
RNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEA
LRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCI
VARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYR
TQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDD
HNWWQGKLENSKNGTAGLIPSPVLQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDK
YLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAY
PIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIH
EQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRT
YAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY"
BASE COUNT 856 a 592 c 663 g 686 t
ORIGIN
1 ccgctatccc ctccggacca tggccgacga cgacgtgctg ttcgaggatg tgtacgagct
61 gtgcgaggtg atcggaaagg gtcccttcag tgttgtacga cgatgtatca acagagaaac
121 tgggcaacaa tttgctgtaa aaattgttga tgtagccaag ttcacatcaa gtccagggtt
181 aagtacagaa gatctaaagc gggaagccag tatctgtcat atgctgaaac atccacacat
241 tgtagagtta ttggagacat atagctcaga tggaatgctt tacatggttt tcgaatttat
301 ggatggagca gatctgtgtt ttgaaatcgt aaagcgagct gacgctggtt ttgtgtacag
361 tgaagctgta gccagccatt atatgagaca gatactggaa gctctacgct actgccatga
421 taataacata attcacaggg atgtgaagcc ccactgtgtt ctccttgcct caaaagaaaa
481 ctcggcacct gttaaacttg gaggctttgg ggtagctatt caattagggg agtctggact
541 tgtagctgga ggacgtgttg gaacacctca ttttatggca ccagaagtgg tcaaaagaga
601 gccttacgga aagcctgtag acgtctgggg gtgcggtgtg atccttttta tcctgctcag
661 tggttgtttg cctttttacg gaaccaagga aagattgttt gaaggcatta ttaaaggaaa
721 atataagatg aatccaaggc agtggagcca tatctctgaa agtgccaaag acctagtacg
781 tcgcatgctg atgctggatc cagctgaaag gatcactgtt tatgaagcac tgaatcaccc
841 atggcttaag gagcgggatc gttacgccta caagattcat cttccagaaa cagtagagca
901 gctgaggaaa ttcaatgcaa ggaggaaact aaagggtgca gtactagccg ctgtgtcaag
961 tcacaaattc aactcattct atggggatcc ccctgaagag ttaccagatt tctccgaaga
1021 ccctacctcc tcaggagcag tctcacaggt gctggacagc ctggaagaga ttcatgcgct
1081 tacagactgc agtgaaaagg acctagattt tctacacagt gttttccagg atcagcatct
1141 tcacacacta ctagatctgt atgacaaaat taacacaaag tcttcaccac aaatcaggaa
1201 tcctccaagc gatgcagtac agagagccaa agaggtattg gaagaaattt catgttaccc
1261 tgagaataac gacgcaaagg aactaaagcg tattttaaca caacctcatt tcatggcctt
1321 acttcagact cacgacgtag tggcacatga agtttacagt gatgaagcat tgagggtcac
1381 acctcctccc acctctccct atttaaacgg cgattctcca gaaagtgcta acggagacat
1441 ggatatggag aatgtgacca gagttcggct ggtacagttt caaaagaaca cagatgaacc
1501 aatgggaatc actttaaaaa tgaatgaact aaatcattgt attgttgcaa gaattatgca
1561 tgggggcatg attcacaggc aaggtacact tcatgttggt gatgaaattc gagaaatcaa
1621 tggcatcagt gtggctaacc aaacagtgga acaactgcaa aaaatgctta gggaaatgcg
1681 ggggagtatt accttcaaga ttgtgccaag ttaccgcact cagtcttcgt cctgtgagga
1741 cttgccatca actacccaac caaaaggacg acagatctat gtaagagcac aatttgaata
1801 tgatccagcc aaggatgacc tcatcccctg taaagaagct ggcattcgat tcagagttgg
1861 tgacatcatc cagattatta gtaaggatga tcataattgg tggcagggta aactggaaaa
1921 ctccaaaaat ggaactgcag gtctcattcc ttctcctgta cttcaggaat ggcgagtagc
1981 ttgcattgcc atggagaaga ccaaacagga gcagcaggcc agctgtactt ggtttggcaa
2041 gaaaaagaag cagtacaaag ataaatattt ggcaaagcac aatgcagtgt ttgatcaatt
2101 agatcttgtc acatatgaag aagtagtaaa actgccagca ttcaagagga aaacactagt
2161 cttattaggc gcacatggtg ttgggagaag acacataaaa aacactctca tcacaaagca
2221 cccagaccgg tttgcgtacc ctattccaca tacaaccaga cctccaaaga aagacgaaga
2281 aaatggaaag aattattact ttgtatctca tgaccaaatg atgcaagaca tctctaataa
2341 cgagtacttg gagtacggca gccacgagga tgcgatgtat gggacaaaac tggagaccat
2401 ccggaagatc cacgagcagg ggctgattgc aatactggac gtggagcctc aggcactgaa
2461 ggtcctgaga actgcagagt ttgctccttt tgttgttttc attgctgcac caactattac
2521 tccaggttta aatgaggatg aatctcttca gcgtctgcag aaggagtctg acatcttaca
2581 gagaacatat gcacactact tcgatctcac aattatcaac aatgaaattg atgagacaat
2641 cagacatctg gaggaagctg ttgagctcgt gtgcacagcc ccacagtggg tccctgtctc
2701 ctgggtctat taggcctctc cccagatatc tgagcataac tgggagcacc tcatttgtgg
2761 aaaagcctct ttgttatcgg ccttgtgtca gcaggtc
//