LOCUS BC143410 3409 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens transmembrane channel-like 3, mRNA (cDNA clone
MGC:176934 IMAGE:9051917), complete cds.
ACCESSION BC143410
VERSION BC143410.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3409)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3409)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: M Column: 6.
FEATURES Location/Qualifiers
source 1..3409
/db_xref="H-InvDB:HIT000501865"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176934 IMAGE:9051917"
/tissue_type="Lung and heart, PCR rescued clones"
/clone_lib="NIH_MGC_317"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GTATGACT"
gene 1..3409
/gene="TMC3"
/db_xref="GeneID:342125"
/db_xref="HGNC:HGNC:22995"
CDS 38..3340
/gene="TMC3"
/codon_start=1
/product="transmembrane channel-like 3"
/protein_id="AAI43411.1"
/db_xref="GeneID:342125"
/db_xref="HGNC:HGNC:22995"
/translation="MKTSKASQRYRGIRRNASQCYLYQESLLLSNLDDSFSADETGDS
NDPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAG
AELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTG
AFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERK
IGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWD
YLIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLLSLAGSI
YLIYFVVDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTL
RFQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFATRTAPEE
EKWSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEM
LKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLHLVY
NQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAML
LFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISS
PVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQ
EESTKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQSMPQSPRPG
DRAPSSPLPGVPKSRLEHETNRYLHGLCASTSDLHRNRSRTPMTFTTHIEDVHSEPLF
RKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINEYDSYKKKHLNVWPERHFKIDAS
GDIVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPPRSLIDLRRAPHF
YIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAYVPRKPRSRNFQYPQPPLKPRG
KPRFEPSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRRKAKSGQEL
TVDLDDLICSNV"
BASE COUNT 891 a 901 c 851 g 766 t
ORIGIN
1 tggccagctt ctgattgtta gcagtgggtt agctcccatg aaaacctcga aggcatccca
61 gcgctataga ggcatccgga gaaatgccag ccagtgctac ctctaccagg aatctctgct
121 gctcagcaac ttggatgaca gctttagtgc tgatgaaaca ggggacagca atgatccgga
181 acaaatcttc cagaatatac agttccagaa agatctcatg gcaaacattc gctgcagacc
241 ctggactatg ggacagaagc tgagggcatt gagacaagcg aagaacattg tgctgaagtt
301 tgaagggagg ctgaccagga cccgaggcta ccaagcagca ggtgcagagc tctggcggaa
361 atttgctcgt ctcgcctgta actttgtggt catcttcatt ccctgggaaa tgaggataaa
421 gaaaatcgag agtcattttg gatctggcgt tgcctcctat ttcatattct tgagatggtt
481 atttggaatt aatattgtgc tcaccattat gacaggtgct tttattgtca ttccagagct
541 gattgcaggc cagccctttg gaagcacagc caggaagacc atccccaagg agcaggtttc
601 gtctgcccaa gacctggaca ccgtctggtc tctggggggc tacctccagt actctgtcct
661 cttctacgga tattacggca gggagaggaa gatcgggaga gctggctacc ggctgccctt
721 ggcgtatttc ctagtgggga tggcagtgtt tgcttacagc ttcatcattc ttttaaaaaa
781 gatggctaag aactcccgca cgagtcttgc cagtgcttcc aatgaaaact ataccttctg
841 ctggcgggtg ttctgtgcct gggattacct cattggaaac ccagaggctg cagagagcaa
901 aacagctgcc atagtgaaca gcatcaggga agctatattg gaagaacagg agaaaaagaa
961 aagcaaaaac ctggcagtga ccatctgcct gaggattatt gccaacatcc tggtgcttct
1021 ctcactggct gggagcattt atctcatcta ctttgtggtg gaccggtccc agaagctgga
1081 gcagtcgaag aaggagctga cactttggga aaagaatgag gtcagtgtgg tggtctccct
1141 cgtcaccatg atagcaccat cagcctttga cctcattgct gccttagaga tgtaccaccc
1201 caggaccacg ctgcgcttcc agcttgcaag ggtccttgtg ctgtatttgg gaaatctcta
1261 cagcctgatc attgctctcc tggacaaagt taacagcatg agcattgagg aaatggctac
1321 caaaaataac acaagtcatt ggatagattc caccaccttc tttgcaacca ggacagctcc
1381 tgaagaagag aaatggtcca catctcggcc tggaatgggg ctcaggagaa acaacacatg
1441 ggccttggaa gagaccagca tttcagctta taccatgcct cttataaagg ccaacaagac
1501 tagcctccac actcagagtc cacaagacca gtgctgggag acatacgttg gtcaggagat
1561 gctgaagctc tccatcattg acatgctctt caccgtggcg agcattctgc tcatagactt
1621 cttccgagga cttttcgtgc ggtacttaag tgactactgg tgttgggatc tggaaagcaa
1681 gtttcctgaa tatggagaat tcaaaatagc tgagaatgtg ctacatttag tctacaacca
1741 aggaatgatt tggatggggg ccttcttctc cccatgtctc ccagcgttca acgttctcaa
1801 actcattggg ctcatgtacc tgagaagctg ggctgtgctg acctgcaatg tgccccacca
1861 gcaagtattt cgagcctcaa gatccaacaa cttctacttg gcaatgctcc tgtttatgct
1921 gtttctgtgc atgctgccaa ccatttttgc tattgtccga tacaagccat ctctaaactg
1981 tgggccattc agtggacaag agaaaattta tgacattgtg tcagaaacga ttgagaaaga
2041 ctttcctgtg tggtttggct ccgtggttgg acacatcagt agccccgtgg tcatcctgcc
2101 cgcagtactc ctgcttttca tgctcatcta ttatctccag agcatcgcac ggtctctaaa
2161 gctcagcaac caccagctca aaatgcagat ccaaaacgca agatcagagg ataagaaaaa
2221 ggttgcccag atggtagaag cccgaatcca gacccaggaa gaaagcacca agaagcttcc
2281 aaacgacagt gatcttacca gccagctgtc ctcagcgcac tcgggcacac cccaaaacaa
2341 cggcaacgtg gcccattttg actcagggag cagcaagagt ggcaggatag agacagtcgc
2401 acagtccatg ccccagagcc cgaggccagg ggacagggct cctagctcac ctctccctgg
2461 ggtccccaaa tccaggctag agcatgaaac taacaggtat ctgcacggtc tgtgtgcaag
2521 caccagtgac cttcacagga acagatcgcg cacacctatg acatttacaa cgcacatcga
2581 agatgtacac tcagaacctc ttttccgaaa agactttcag caaatcaacc ctcctcaccg
2641 tggaccacag gcctcgactt tgctggcaca gggtcccagg ccccacgccc ccagatacta
2701 tgtcattaat gaatatgact cttacaagaa aaaacatcta aatgtctggc cagaaagaca
2761 tttcaagata gatgcttcag gtgacattgt ggagctgtac cccaggaacg tgcgacaata
2821 tgcatcccgg gtcccccgcc agcctccctc cccacagctg agtgaagaag aggaggagac
2881 gccaagcaga gattggatca aacggtctct tcccccacgc tccctgatag acctccgtcg
2941 ggctcctcat ttttatattg gggagaggtc cgaaagtcag acccgggatc ccgagcacca
3001 ggggagggtg cactacaagt cgtggaatga agattttgag ggtcaccttg agaggccagc
3061 ctatgtgccc agaaagccac gatcccggaa tttccaatac ccacagcccc ctctgaagcc
3121 cagagggaag cccaggttcg agccatccct cacggaatct gactccgtgt cggcagcatc
3181 cagcagtgac cagcagaaca gcagcgctga ccagtacctg caggtcaccc acagccaggg
3241 caggttcccg aggtccgtgg gccagcccag caggaggaag gccaagtcgg ggcaggagct
3301 gaccgtggat ctggatgact tgatttgttc aaatgtctag gcttcctcca gtgtcccgtt
3361 cctagaggtc aggcccctgt tggagtgctg ggccagcaca tggcatctc
//