LOCUS BC143347 3850 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10-like,
mRNA (cDNA clone MGC:176869 IMAGE:9051852), complete cds.
ACCESSION BC143347
VERSION BC143347.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3850)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3850)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: O Column: 23.
FEATURES Location/Qualifiers
source 1..3850
/db_xref="H-InvDB:HIT000501805"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176869 IMAGE:9051852"
/tissue_type="Colon, PCR rescued clones"
/clone_lib="NIH_MGC_294"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: TCATCGCC"
gene 1..3850
/gene="ARHGEF10L"
/gene_synonym="GrinchGEF"
/gene_synonym="RP11-473A10.1"
/db_xref="GeneID:55160"
/db_xref="HGNC:HGNC:25540"
/db_xref="MIM:612494"
CDS 34..3756
/gene="ARHGEF10L"
/gene_synonym="GrinchGEF"
/gene_synonym="RP11-473A10.1"
/codon_start=1
/product="Rho guanine nucleotide exchange factor (GEF)
10-like"
/protein_id="AAI43348.1"
/db_xref="GeneID:55160"
/db_xref="HGNC:HGNC:25540"
/db_xref="MIM:612494"
/translation="MASSNPPPQPAIGDQLVPGVPGPSSEAEDDPGEAFEFDDSDDEE
DTSAALGVPSLAPERDTDPPLIHLDSIPVTDPDPAAAPPGTGVPAWVSNGDAADAAFS
GARHSSWKRKSSRRIDRFTFPALEEDVIYDDVPCESPDAHQPGAERNLLYEDAHRAGA
PRQAEDLGWSSSEFESYSEDSGEEAKPEVEVEPAKHRVSFQPKMTQLMKAAKSGTKDG
LEKTRMAVMRKVSFLHRKDVLGDSEEEDMGLLEVSVSDIKPPAPELGPMPEGLSPQQV
VRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH
SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTK
PAFLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLA
LTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTETV
YGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYVVKWNTAL
PQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGPPRLFQELQDLQKDL
AVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGK
PDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFW
CPILACCIPAFSSRALSLQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGG
QVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTIC
LGLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTS
GGVLWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQD
EAVSVTHMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIATRTTFLLPGQKHLCVT
SLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSILA
PDILRSDQEEAEGPRAEEDKPDGQAHEPMPDSHVGRELTRKKGILLQYRLRSTAHLPG
PLLSMREPAPADGAALEHSEEDGSIYEMADDPDVWVRSRPCARDAHRKEICSVAIISG
GQGYRNFGSALGSSGRQAPCGETDSTLLIWQVPLML"
BASE COUNT 741 a 1248 c 1195 g 666 t
ORIGIN
1 gggacggtgc tggtctgagc tggaccttgt ctgatggctt cctccaaccc tcctccacag
61 cctgccatag gagatcagct ggttccagga gtcccaggcc cctcctctga ggcagaggac
121 gacccaggag aggcgtttga gtttgatgac agtgatgatg aagaggacac cagcgcagcc
181 ctgggcgtcc ccagccttgc tcctgagagg gacacagacc ccccactgat ccacttggac
241 tccatccctg tcactgaccc agacccagca gctgctccac ccggcacagg ggtgccagcc
301 tgggtgagca atggggatgc agcggacgca gccttctccg gggcccggca ctccagctgg
361 aagcggaaga gttcccgtcg cattgaccgg ttcactttcc ccgccctgga agaggatgtg
421 atttatgacg acgtcccctg cgagagccca gatgcgcatc agcccggggc agagaggaac
481 ctgctctacg aggatgcgca ccgggctggg gcccctcggc aggcggagga cctaggctgg
541 agctccagtg agttcgagag ctacagcgag gactcggggg aggaggccaa gccggaggtc
601 gaggtcgagc ccgccaagca ccgagtgtcc ttccagccca agatgaccca gctcatgaag
661 gccgccaaga gcgggaccaa ggatgggctg gagaagacac ggatggccgt gatgcgcaaa
721 gtctccttcc tgcacaggaa ggacgtcctc ggtgactcgg aggaggagga catggggctc
781 ctggaggtca gcgtttcgga catcaagccc ccagccccag agctgggccc catgccagag
841 ggcctgagcc ctcagcaggt ggtccggagg catatcctgg gctccatcgt gcagagcgaa
901 ggcagctacg tggagtctct gaagcggata ctccaggact accgcaaccc cctgatggag
961 atggagccca aggcgctgag cgcccgcaag tgccaggtgg tgttcttccg cgtgaaggag
1021 atcctgcact gccactccat gttccagatc gccctgtcct cccgcgtggc tgagtgggat
1081 tccaccgaga agatcgggga cctcttcgtg gcctcgtttt ccaagtccat ggtgctagat
1141 gtgtacagtg actacgtgaa caacttcacc agtgccatgt ccatcatcaa gaaggcctgc
1201 ctcaccaagc ctgccttcct cgagttcctc aagcgacggc aggtgtgcag cccagaccgt
1261 gtcaccctct acgggctgat ggtcaagccc atccagaggt tcccacagtt catactcctg
1321 cttcaggaca tgctgaagaa cacccccagg ggccatccgg acaggctgtc gctgcagctg
1381 gccctcacag agctggagac gctggctgag aagctgaacg agcagaagcg gctggctgac
1441 caggtggctg agatccagca gctgaccaag agcgtcagtg accgcagcag cctcaacaag
1501 ctgttgacct caggccagcg gcagctgctc ctgtgtgaga cgttgacgga gaccgtgtac
1561 ggtgaccgcg ggcagctaat taagtccaag gagcgtcggg tcttcctgct caacgacatg
1621 cttgtctgtg ccaacatcaa cttcaagcct gccaaccaca ggggccagct ggagatcagc
1681 agcctggtgc ccctggggcc caagtatgtg gtgaagtgga acacggcgct gccccaggtg
1741 caggtggtgg aggtgggcca ggacggtggc acctatgaca aggacaatgt gctcatccag
1801 cactcaggcg ccaagaaggc ctctgcctca gggcaggctc agaataaggt gtacctcggc
1861 cccccacgcc tcttccagga gctgcaggac ctgcagaagg acctggccgt ggtggagcag
1921 atcacgcttc tcatcagcac gctgcacggc acctaccaga acctgaacat gactgtggct
1981 caagactggt gcctggccct gcagaggctg atgcgggtga aggaggaaga gatccactcg
2041 gccaacaagt gccgtctcag gctcctgctt cctgggaaac ccgacaagtc cggccgcccc
2101 attagcttca tggtggtttt catcaccccc aaccccctga gcaagatttc ctgggtcaac
2161 aggttacatt tggccaaaat cggactccgg gaggagaacc agccaggctg gctatgcccg
2221 gatgaggaca agaagagcaa agccccattc tggtgcccga tcctggcctg ctgcatccct
2281 gccttctcct cccgggcact cagcctgcag cttggggccc tggtccacag tcctgtcaac
2341 tgtcccctgc tgggtttctc agcagtcagc acctcccttc cacagggcta cctctgggtc
2401 gggggcggac aggaaggcgc agggggccag gtggaaatct tttccttgaa ccggccctcg
2461 ccccgcaccg tcaagtcctt cccactggca gcccctgtgc tctgcatgga gtatatcccg
2521 gagctggagg aggaggcgga gagcagagac gagagcccga cagttgctga cccctcggcc
2581 acggtgcatc caaccatctg cctcgggctc caggatggca gcatcctcct ctacagcagt
2641 gtggacactg gcacccagtg cctggtgagc tgcaggagcc caggtctgca gcctgtgctc
2701 tgcctgcgac acagcccctt ccacctgctc gctggcctgc aggatgggac ccttgctgct
2761 taccctcgga ccagcggagg tgtcctgtgg gacctggaga gccctcccgt gtgcctgact
2821 gtggggcccg ggcctgtccg caccctgttg agcctggagg atgccgtgtg ggccagctgt
2881 gggccccggg tcactgtcct ggaagccacc accctgcagc ctcagcaaag cttcgaggcg
2941 caccaggacg aggcagtgag cgtgacacac atggtgaagg cgggcagcgg cgtctggatg
3001 gccttctcct ccggcacctc catccgcctc ttccacactg agaccctgga gcatctgcaa
3061 gagatcaaca tcgccaccag gaccaccttc ctcctgccag gccagaagca cttgtgtgtc
3121 accagcctcc tgatctgcca gggtctgctc tgggtgggca ctgaccaggg tgtcatcgtc
3181 ctgctgcccg tgcctcggct ggaaggcatc cccaagatca cagggaaagg catggtctca
3241 ctcaatgggc actgtgggcc tgtggccttc ctggctgtgg ctaccagcat cctggcccct
3301 gacatcctgc ggagtgacca ggaggaggct gaggggcccc gggctgagga ggacaagcca
3361 gacgggcagg cacacgagcc catgcccgac agccacgtgg gccgagagct gacccgcaag
3421 aagggcatcc tcttgcagta ccgcctgcgc tccaccgcac acctcccggg cccgctgctc
3481 tccatgcggg agccggcgcc tgctgatggc gcagctttgg agcacagcga ggaggacggc
3541 tccatttacg agatggccga cgaccccgac gtctgggtgc gcagccggcc ctgcgcccgc
3601 gacgcccacc gcaaggagat ttgctctgtg gccatcatct ccggcgggca gggctaccgc
3661 aactttggca gcgctctggg cagcagtggg aggcaggccc cgtgtgggga gacggacagc
3721 accctcctca tctggcaggt gcccttgatg ctatagcgcc tcccctctcc cctcagaggg
3781 cacagctgca ggcctgacca aggccacgcc cggctctcgt gctctaggac ctgcacggga
3841 cttgtggatg
//